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Katon Abdul Fatah
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Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE)
Published by Lembaga Pengembangan Kinerja Dosen
ISSN : 2828934X     EISSN : 28289358     DOI : https://doi.org/10.55606/jurrike.v1i2
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health Veterinary
Jurnal Riset Rumpun Ilmu Kedokteran adalah jurnal yang ditujukan untuk publikasi artikel ilmiah yang diterbitkan oleh Pusat riset dan Inovasi Nasional, Universitas Sains dan Teknologi Komputer. Jurnal ini adalah jurnal Riset Rumpun Ilmu Kedokteran yang bersifat peer-review dan terbuka. Bidang kajian dalam jurnal ini termasuk sub rumpun Ilmu Kedokteran Spesialis, Ilmu Kedokteran Akademik, Spesialis Kedokteran gigi dan mulut, Kedokteran Gigi Akademik. Jurnal Riset Rumpun Ilmu Kedokteran menerima artikel dalam bahasa Inggris dan bahasa Indonesia dan diterbitkan 2 kali setahun: April dan Oktober.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 331 Documents
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Pengaruh Variasi Tween 80 dan Propilen Glikol terhadap Karakteristik Nanoemulsi Lotion Daun Ubi Jalar Ungu (Ipomoea batatas L.) Riska Amelia; Danang Raharjo; Bangkit Riska Permata
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 5 No. 2 (2026): Agustus: Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v5i2.10357

Abstract

Exposure to ultraviolet radiation and environmental pollution triggers an increase in free radicals in the skin, leading to oxidative stress and premature aging. Purple sweet potato leaves (Ipomoea batatas L.) contain high antioxidant compounds such as anthocyanins and flavonoids; however, conventional topical applications face stability and penetration challenges. Nanoemulsions serve as a solution to enhance the penetration and stability of active compounds. This study aimed to analyze the effect of Tween 80 and propylene glycol variations on the characteristics of nanoemulsion lotion from purple sweet potato leaves. This laboratory experimental research employed a completely randomized design (CRD) using five formulas with varying concentrations of Tween 80 (30-35%) and propylene glycol (5-15%). The extract was obtained through maceration using 96% ethanol and formulated into a nanoemulsion lotion using a high-speed homogenization method. Evaluations included organoleptic, homogeneity, pH, viscosity, spreadability, adhesion, particle size, and polydispersity index (PDI) tests. The results showed that all formulas produced semisolid, homogeneous preparations with pH of 5.21-6.31, viscosity of 2,063-3,075 cPs, spreadability of 6.17–7.88 cm, and adhesion of 4.63–5.96 seconds. Formula F4 (Tween 80:propylene glycol 55:15) exhibited the best characteristics with the smallest particle size of 128.54 nm and PDI of 0.187. Variations in Tween 80 and propylene glycol significantly influenced the characteristics of the nanoemulsion lotion. Formula F4 is recommended as the optimal formulation for developing nanoemulsion lotions based on purple sweet potato leaves.

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