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Jurnal Ilmiah Sains
Published by Universitas Sam Ratulangi
ISSN : 14123770     EISSN : 25409840     DOI : https://doi.org/10.35799/jis.v22i2.40961
Core Subject : Science, Education, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Mathematics Physics
Jurnal Ilmiah Sains (Journal of Scientific Sciences) is the Journals Published by Faculty of Mathematics and Natural Sciences, Sam Ratulangi University. Jurnal Ilmiah Sains Published Twice a Year, i.e April and October. Jurnal Ilmiah Sains  welcomes full research articles in the area of Mathematics and Natural Sciences from the following subject areas: Mathematics Statistics Computer Science Physics Chemistry Biology
Arjuna Subject : Umum - Umum
Articles 8 Documents
 1 
Search results for , issue "Volume 23 Nomor 1, April 2023" : 8 Documents clear
Antihyperglycemic Activity Test of Ethanol Extract, Methanol and n-Hexane Fraction of Taro Leaves (Colocasia esculenta (L) Schott) Rachma Nurhayati; Nadia Pramasari; Rosa Hesturini
Jurnal Ilmiah Sains Volume 23 Nomor 1, April 2023
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jis.v23i1.43998

Abstract

Taro leaf (Colocasia esculenta (L) Schott) is a plant from the Araceae family that has antihyperglycemic activity because it contains secondary metabolites such as flavonoids, tannins, saponins, polyphenols and alkaloids. This study was aimed to determine the antihyperglycemic activity of ethanol extract, methanol fraction and n-hexane fraction of taro leaves given to male white rats after streptozotocin and alloxan were induced. The experimental research method used 55 male white rats with 6 treatments. Group 1 normal, group 2 negative control CMC-Na, group 3 positive control metformin 500 mg, group 4 ethanol extract at a dose of 200 mg/Kgbb (streptozotocin induction), group 5 methanol fraction at a dose of 38, 1 mg/KgBW (streptozotocin induction), group 6 n-hexane fraction at a dose of 9,2 mg/KgBW (streptozotocin induction), group 7 ethanol extract at a dose of 200 mg/Kgbb (aloxan induction), group 8 methanol fraction at a dose of 38, 1 mg/KgBW (aloxan induction) and group 9 n-hexane fraction at a dose of 9,2 mg/KgBW (aloxan induction). Glucose levels were checked using an Easy Touch glucometer. The results showed that statistically the ethanol extract of taro leaves at a dose of 200 mg/KgBW was the most effective in lowering blood glucose in male white rats. Keywords: Antihyperglycemia; extract; fraction; taro leaves
An antioxidant capacity of ethanol and ethyl acetate extracts of areca nut (Pinanga ceasia Blume), a plant endemic to Central Sulawesi Elizabeth B.E Kristiani; Jeanelsin A.P Langgori
Jurnal Ilmiah Sains Volume 23 Nomor 1, April 2023
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jis.v23i1.46097

Abstract

The purpose of this study to measure the antioxidant ability and content of phenolic and flavonoid compounds in ethanol and ethyl acetate extracts of areca nut (Pinanga ceasia Blume) taken from the Central Sulawesi region. The fruit were divided in the skin, seeds, and flesh. Samples were extracted by maceration using two types of solvents, namely ethanol and ethyl acetate. The parameters of the study were measured spectrophotometrically using specific reagents. The reagents used were DPPH for antioxidant activity test, Folin-Ciocalteu reagent for testing phenolic compound levels, and AlCl3 reagent for flavonoid level testing. The phenolic content of the ethanolic extract of the seeds and fruit flesh was in the range of 3,500 – 4,500 g equivalent of gallic acid/g extract, while the flavonoid content was in the range of 1,700 – 1,800 g equivalent of quercetin/g of extract. This value is much higher than other extracts in the range of 170 – 740 g bioactive equivalent/g extract. The antioxidant ability of the ethanol extract of the seeds and fruit pulp increased with increasing concentration of the extract, while the other extracts were relatively the same at all test concentrations. Keywords: antioxidant; flavonoid; maceration; phenolic; Pinanga ceasea Blume Kapasitas Antioksidan Ekstrak Etanol dan Etil Asetat Buah Pinang (Pinanga ceasia Blume), Tanaman Endemik Sulawesi Tengah ABSTRAK Penelitian ini bertujuan untuk untuk mengukur kemampuan antioksidan dan kadar senyawa fenolik dan flavonoid pada ekstrak etanol dan etil asetat buah pinang (Pinanga ceasia Blume) yang diambil dari daerah Sulawesi Tengah. Buah pinang dipisahkan bagian kulit, biji, dan daging buah. Sampel diekstraksi secara maserasi menggunakan dua jenis pelarut yaitu etanol dan etil asetat. Parameter uji diukur secara spektrofotometri menggunakan reagen spesifik. Reagen yang digunakan yaitu DPPH untuk uji aktivitas antioksidan, reagen Folin-ciocalteu untuk uji kadar senyawa fenolik, dan reagen AlCl3 untuk uji kadar flavonoid. Kadar fenolik ekstrak etanol biji dan daging buah pada kisaran 3.500 – 4.500 µg ekivalen asam galat/g ekstrak sedangkan flavonoid pada kisaran 1.700 – 1.800 µg ekivalen kuersetin/g ekstrak. Nilai tersebut jauh lebih tinggi dibanding ekstrak lain yang ada pada kisaran 170 – 740 µg ekivalen bioaktif/g ekstrak. Kemampuan antioksidan ekstrak etanol biji dan daging buah meningkat seiring meningkatnya konsentrasi ekstrak sedangkan ekstrak lain relative sama pada semua konsentrasi uji. Ekstrak etanol biji dan daging buah Pinanga ceasea Blume memiliki kadar flavonoid dan flavonoid lebih dari dari kulit buah. Kemampuan antioksidan ekstrak etanol biji dan daging buah Pinanga ceasea Blume lebih tinggi dibandingkan ekstrak lain. Kata kunci: Antioksidan; fenolik; flavonoid; maserasi; Pinanga ceasea Blume
Evaluation of Growth Response of Superwin Rice Variety to Salinity at The Germination Phase Billy Deivico Manis; Susan Marlin Mambu; Song Ai Nio
Jurnal Ilmiah Sains Volume 23 Nomor 1, April 2023
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jis.v23i1.45076

Abstract

Evaluation of the salinity resistance of Superwin as a local rice of North Sulawesi, is still very limited. This study aimed to examine the growth response of Superwin compared with Ciherang variety to various levels of seawater salinity at the germination phase. The research commenced with planting rice seeds using the Roll Paper Test method, then growing them under salinity treatments of 0, 10, and 20% seawater. The observed rice growth responses were the percentage of germination, the length of seminal root and shoot, the ratio of seminal root length: shoot length and the vigor index. The results of analysis of variance (ANOVA) showed that the percentage of germination, the length of seminal root and shoot, and vigor index were significantly different between two varieties and among salinity treatments. The interaction between factors of variety and salinity treatment caused differences in the ratio of seminal root length: shoot length. Superwin showed higher percentage of germination, the length of seminal root and shoot as well as vigor index than Ciherang. The 0% and 10% salinity treatments showed a higher percentage of germination, the length of seminal root and shoot as well as vigor index than the 20% treatment. The ratio of seminal root length and shoot length was a potential indicator of salinity stress in Superwin rice. Keywords: Germination; rice; salinity; superwin
Analysis of Hydroquinone and Kojic Acid Content in Three Brand Body Lotions Using High Performance Liquid Chromatography Yessy Dwi Anggraini; Khoirul Anwar; Aqnes Budiarti
Jurnal Ilmiah Sains Volume 23 Nomor 1, April 2023
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jis.v23i1.45703

Abstract

Treatment of hyperpigmentation can be done with several compounds, including a combination of hydroquinone and kojic acid in cosmetic preparations that are considered safe and effective. This study aims to analyze the levels of hydroquinone and kojic acid in three trademarks of body lotion using HPLC.  The study used HPLC at a wavelength of 283 nm. The stationary phase used was C18, and the mobile phase was a mixture of acetonitrile:aquabidest (20:80, v/v) with a flow rate of 1.0 mL/min. Validation tests were carried out, including linearity, sensitivity (LOD and LOQ), selectivity, precision, and accuracy. The analytical method was applied to 3 body lotion preparations.  The linearity test of hydroquinone and kojic acid with a value of r = 0.999; Hydroquinone LOD 0.274 g/mL; LOQ of hydroquinone 0.913 g/mL; LOD of kojic acid 0.420 g/mL; LOQ of kojic acid 1,401 g/mL; selectivity test 1.5; the precision test of hydroquinone and kojic acid resulted in the value of %RSD 2%; hydroquinone accuracy 99.200-100.450%; kojic acid 99.454-100.450%. The content of hydroquinone body lotion brand A, 0.854%, B 0.470%, and C 1.557%, kojic acid content in body lotion brand A 0.823%, B 0.510%, and C 1.497%. The results showed that all the results of the validation test fulfill the requirements of the validation parameters and the results of the analysis of the content of hydroquinone and kojic acid in the three trademarks of body lotion fulfill the requirements. Keywords: Body lotion; hydroquinone levels; kojic acid  
Odd Harmonious Labeling of the Zinnia Flower Graphs Fery Firmansah; Tasari Tasari; Muhammad Ridlo Yuwono
Jurnal Ilmiah Sains Volume 23 Nomor 1, April 2023
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jis.v23i1.46771

Abstract

An odd harmonious graph is a graph that satisfies the odd harmonious labeling properties. In this study, a new graph class construction is presented, namely zinnia flower graphs and variations of the zinnia flower graphs. The research method used is qualitative and includes several phases, namely data collection, data processing and analysis, and verification of the results. The purpose of this research is to find a new class of graphs that is a family of odd harmonious graphs. We will prove that prove that the zinnia flower graph and its variations satisfy odd harmonious labeling properties. The result of this research is that the zinnia flower graph and its variations are odd harmonious graphs. Keywords: Flower graph; odd harmonious graph; odd harmonious labelling; zinnia flower  graph Pelabelan Harmonis Ganjil dari Graf Bunga Zinnia ABSTRAK Graf yang memiliki sifat pelabelan harmonis ganjil adalah graf harmonis ganjil. Pada penelitian ini akan didapatkan konstruksi graf bunga zinnia dan variasi graf bunga zinnia. Metode penelitian yang digunakan adalah penelitian kualitatif yang terdiri beberapa tahapan yaitu pengumpulan data, pengolahan dan analisis data, serta verifikasi hasil. Tujuan penelitian ini adalah menemukan kelas graf baru yang merupakan keluarga dari graf harmonis ganjil. Hasil penelitian ini diperoleh bahwa graf bunga zinnia dan variasi graf bunga zinnia merupakan graf harmonis ganjil. Kata kunci: Graf bunga; graf bunga zinnia; graf harmonis ganjil; pelabelan harmonis ganjil
Effect of Dalugha (Cyrtosperma merkusii) Debris Supplementation on Hemoglobin, Cholesterol and Blood Glucose Levels in Broiler Chickens Debby J.J. Rayer; Emma Mauren Moko; Dino Rahardiyan; Anita C.C Tengker; Christny F. Rompas; Livana Dethris Rawung
Jurnal Ilmiah Sains Volume 23 Nomor 1, April 2023
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jis.v23i1.47598

Abstract

Feed is an important factor that influences the chicken's development and growth. Meanwhile, dalugha debris is a by-product of dalugha processing which is expected to be a source of feed for the growth and development of broiler chickens. The good feed can optimize metabolic processes in the animal so that it can support the process of growth and development of the animal. This study aims to determine the levels of hemoglobin, cholesterol, and blood glucose in broiler chicken that is given dalugha debris supplementation. This study used a completely randomized design (CRD), where as many as 60 docs of unsex chicken used were divided into four treatments and three replications. Each replication consisted of five chickens. The treatment given was the concentration of dalugha debris at several doses: 0%, 0.065%, 0.13%, and 0.26%. The parameters observed were hemoglobin, cholesterol, and blood glucose levels. The results showed that the provision of dalugha debris in the feed significantly (p<0.05) affected the blood glucose level, but did not affect the cholesterol and hemoglobin levels (p>0.05) of the broiler chicken. Keywords: Broiler chicken; blood biochemistry; Cyrtosperma merkusii
Unit Linked Life Insurance Premium Reserve Modification Using Fackler and Point to Point Methods Sheren Rosari Monica Rachmad; Tohap Manurung; Chriestie E.J.C Montolalu
Jurnal Ilmiah Sains Volume 23 Nomor 1, April 2023
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jis.v23i1.46228

Abstract

The present study aims to investigate the use of the Fackler method in determining the reserve of unit-linked whole life insurance premiums. Unit-linked whole life insurance combines both protection and investment features, and to mitigate liquidity risks, it is crucial for the insurer to establish reserves. The insurer limits the value of the benefits obtainable through a minimum guarantee and stamp value to counteract losses that may arise due to fluctuations in share prices.The Fackler method is employed to calculate the reserve of unit-linked whole life insurance premiums by determining the cash value of annuities using a fixed interest rate in conjunction with the Indonesia Mortality Table 2019. Subsequently, an annual net premium is calculated. The calculation of the annual net premium necessitates the determination of a single net premium, which is computed using the Point to Point method with the result is . The outcome of this calculation yields the reserve value for a 40-year-old individual. It is noteworthy that the reserve value will increase with the lifespan of the individual or the duration of the policy contract. Keywords : Fackler method;  premium reserves; Unit-linked
Quality and Antioxidant Activity of Scrub Bath Soap with Addition of Eucheuma spinosum Algae Powder Firdayanti Paputungan; Lidya Irma Momuat; Edi Suryanto
Jurnal Ilmiah Sains Volume 23 Nomor 1, April 2023
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jis.v23i1.48540

Abstract

A study was conducted to evaluate the quality and antioxidant activity of solid body soap with the addition of Eucheuma spinosum powder as a scrub. Soap was made by the saponification method between oil (a mixture of olive oil (44%), coconut (24%), and palm (32%)) with NaOH. This study consisted of 4 treatments: (1) without adding algae powder (control) with cold process (TC), (2) adding algae powder with cold process (SC), (3) without adding algae powder (control) with hot process (TH), and (4) the addition of algae powder with a hot process (SH). Soap quality was evaluated using the Indonesian National Standard (SNI) 3532:2021 method, and antioxidant activity using the DPPH method. Parameters tested consisted of pH, total fat, water content, matter insoluble in ethanol, free fatty acids, chlorides, non-saponifiable fats, and the percentage of DPPH inhibition. The results showed that the quality of scrub soap complied with SNI for parameters of pH, content of water, matter insoluble in ethanol and chloride; and did not meet SNI for parameters of total fat, content of free fatty acid and unsaponifiable fat. The percentage of DPPH inhibition of each bath soap at a concentration of 150 µg/mL soap solution was 58.97% TC, 76.76% SC, 56.11% TH and 70.13% SH. Scrub soap with the addition of algae powder had higher antioxidant activity than without the addition of algae powder, both in cold and hot processes. Keywords: Antioxidant;  Eucheuma spinosum; scrub bath soap; SNI

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