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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
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Some Ratios of Blood Components and their Correlation to the Special Endurance of the Block Skill in Volleyball Bassem Hassan Ghazi
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

The research included four sections as the research dealt with some physiological problems that affect the level of players to the skill of block when repeated several times during the game.The Aim of Research is toIdentify the levels of endurance to the block and blood components of the players of the Faculty of Physical Education and Sports Sciences in the volleyball / University of Kufa.To identify the relationship between the components of blood in search and endurance of the block in the volleyball.As for the imposition of the research, there is a significant correlation between the blood components and endurance of the block in the volleyball.The researcher chose the descriptive approach to suit the nature and problem of the research. The researcher selected the research sample from the research society represented by the players of the Faculty of Physical Education and Sports Sciences / Kufa University in the volleyball for the academic year 2017-2018 and the number of (12) player was selected (8)players ,they represent (66.66%) of the research community. And thus represent it genuinely.The Most Important ConclusionsThe proportion of hemoglobin in volleyball players has to do with the endurance of the block.The blood viscosity of volleyball players has to do with the special endurance of the block.There is no significant correlation between the endurance of the block and the number of white blood cells and red platelets.As for hypothesis of the research, there is a significant correlation between the blood components and endurance of the block in the volleyball.The Most Important RecommendationsEmphasis on the level of health of players, especially blood components because of the impact on the levels of players in various skills.Conduct periodic tests and tests for the players to check their blood components.The use of medical treatment when there is a weakness in the proportions of blood components by specialists.Keywords: Blood components, Special endurance and block skill.
Molecular Analysis of Type 1 Fimbriae Operon in E. coli Isolated from UTI Duaa Al-Musawi
Journal of Global Pharma Technology Volume 11 Issue 04.
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Abstract

One hundred E.coli isolates wascollected from urinary tract infections. Patients aged between 2 and 73 years, 66 females, 34 males. E. coli's commitment to urinary epithelial cells appears to be 100% in local isolates and the ability of bacteria to form biofilm was detected by using conjured-plate method and result showed that 96% of these isolated capable to form biofilm and only 4 isolates non-producer. Types1 fimbrial adhesions are encode by a fimgene clusters, include nine gene essential for the biosynthesis. ( FimB, Fim E, fim A , FimI, Fim C, FimD, FimF, FimG, FimH )  according to this study all the above mentioned genes were  detection using PCR technique but there percentage were differ with (93% , 85% , 98%, 98% , 100% , 100% , 100% ,100% ,98%) respectively . the results indicated that isolates were negative for fim H gene may be negative for biofim formation this indicated the importance of type 1 fimbriae in biofilm formation.Keywords: Uropathogenic Escherichiacoli (UPEC); Bioflim, (PCR); Type1fimbriae.
The Comparative Analysis of Asthma Treatment in Pediatric Patients of Russia and China Yue Li
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
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Abstract

The correctly prescribed treatment regimen plays a key role in a successful control of asthma symptoms. Therefore, the monitoring studies aimed to facilitate rational medicine use for asthma treatment are relevant. The analysis of drug prescription patterns for asthma in pediatric outpatient care of Russia and China, as well as evaluation of the prescribed therapy conformity with the modern international standards on asthma treatment. This is a retrospective pharmacoepidemiological study on medical histories of asthma patients under the age of 18. The study involved 720 children’s medical records (327 Russian and 393 Chinese) and prescribed medications for asthma within the period of 2018. The short-acting beta-2-agonists in Russia and China were typically prescribed as quick-relief drugs for treating asthma attacks in pediatric patients (in 78.6% and 83.7% of cases, respectively (p> 0.05)). Inhaled corticosteroids (in 65.1% of cases) and leukotriene receptor antagonists (in 18.6% of children) were most frequently prescribed for a long-term control of asthma symptoms in China. In Russia, the rate of commonly prescribed long-term relievers ranged as follows: inhaled corticosteroids -54.1%, cromones-19.6%, inhaled corticosteroids in combination with long-acting beta-2-agonists -15.4%. The drug prescribing patterns for bronchial asthma management in pediatric patients of Russia and China conformed to the modern treatment standards. Still, some differences in asthma therapy (relatively short anti-inflammatory therapy courses, unreasonably prescribed cromons in Russia) were found, which required deeper pharmacoepidemiological monitoring in that field. Keywords: Commonly prescribed asthma medications in pediatric patients, Mistakes in pediatric asthma management, Asthma medication prescribing in China and Russia.
Antibiofilm Activity of Intracellular Extracts of Westiellopsis prolifica Isolated From Local Environment in Baghdad Shurooq Latif Al-Tmimi
Journal of Global Pharma Technology .
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Abstract

Acetone and hexane extracts of cyanobacteria Westiellopsis  prolifica was tested In vitro. Antibiofilm  activity was evaluated by biofilm production assay against six  pathogenic bacteria in which three are Gram- positive bacteria  "Staphylococcus aureus , B.subtilis, and Streptococcus sp. "  and three  are Gram- negative bacteria" Shigella sp., Proteus sp. and Pseudomonas aeruginosa " in additions two isolates of fungi "Aspergills niger  and Candida albicans".The results showed that crude acetone extract for W .prolifica better than hexane extract ,and  more efficient on negative gram bacteria than positive gram bacteria. The highest biofilm inhibition of acetone extract against Shigella sp. reached to (10 ) %, while lower biofilm inhibition ( 68)% against A. niger compared to hexane, with the highest biofilm inhibitory rate in C.albicans  (42 )% and lower biofilm inhibition against Proteus sp. reached to ( 98 )%.at concentration 100 µl. As well as  Congo red agar  method showed that acetone extract for W .prolifica better than hexane extract in the anti-biofilm formation at 50 µl, The best anti-biofilm activity of   acetone extract  against  B. subtilis , Shigella sp., Proteus sp. and C. albicans  (++ )While A. niger (+) showed slight  effectiveness .On the other hand the hexane extract showed little efficacy against biofilm for all studied isolates .Key words: Westiellopsis prolifica, Active compounds, Antibiofilm, Partial purification, GC/MS Analysis.
Improving Nursing Performance Quality in CPCR: A Cooperative Action Research Study Mohsen Shahriari
Journal of Global Pharma Technology Volume 08 Issue 06
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Abstract

Introduction: cardiopulmonary arrest is the major factor beneath many deaths in world every hour, which nurses can save more lives with fast and correct CPCR. All studies showed that Survival rate and outcome of CPCR correlates closely with performing the process fast and correctly. Hence, this research was designed and carried out to improve nursing performance quality in CPCR.Materials and Methods: this is a cooperative action research study using repeated cycles as Kemmis plan (plan, administration, evaluation & reflecting) in Motahari hospital affiliating with Jahrom university of Medical Sciences-2013-2014. 50 practitioner nurses participated in the study and were assessed by ER head nurse (1-week observation, pre-test knowledge and practice by questionnaire and OSCE test). Planning was done by 10 participants including staff and head nurses in 2 theory and clinical phases for 6 months. European Resuscitation Council and American heart association Guidelines has been used. Education was done in the form of workshop (6 nurses) for 10 groups, 70 sessions (2-4 hours), every group 6-8 sessions. Paired T-test was used to determine statistical significance in evaluation phase. This plan was changed, refined and developed through reflection phase.Findings: Mean of OSCE pre-test and post-test were (.3244) and (.9306), respectively, so that Paired samples T test (p=0.0001) revealed that there was a significant difference between them. Mean of theory pre- and post-test quiz were (.5093) and (.9181) respectively, so that Paired samples T test (p=0.0001) revealed that there was a significant difference between them.Conclusions: it appears that a comprehensive and operational plan by participant on the basis of their actual need is more effective than any other CNE plans. According to the results of this research, this method for CPCR education this method for CPCR education in all hospitals affiliated to Jahrom university medical sciences.Keywords: Action Research, Nursing, Cpcr, Quality
Degradation High Concentration of Eosin Yellowish Dye in Heterogeneous Catalyst Solution Ihab Abbas Taher
Journal of Global Pharma Technology .
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Abstract

Eosin yellowish was intended to be degraded by the use of photo catalysis process which is proposed to be mediated by ZnO and irradiated under visible light. Effects of variant swayful factors were studied for instance dosage of catalyst, concentration of dye and the incipient pH. A huge number of intermediates which yielded from photo degradation were disunited, identified, and distinguished via ultra performance to gain a well concept about the photo degradation of eosin yellowish dye assisted by ZnO and the mechanistic details related to this process which depends upon irradiation with visible light of low watt. As a photo catalyst, ZnO was depended in the current paper to perform the degradation process of eosin yellowish dye under UV light via a slurry reactor. Depending upon varying concentrations of catalyst and initial dye as (0.3 – 1.5 g/l) and (20 – 120 mg/l) respectively, different parameters optimum values were gained videlicet concentration of catalyst, initial substrate concentration that affects the eosin yellowish dye degradation rate and the type of catalyst. The diminishing of substrates and colour as concomitant with the diminution of total content of organic carbon was monitored.          Keywords:  Heterogeneous reaction; Eosin yellowish dye; Degradation dyes
Effect of Modified Form of Porcelanite Rocks to Remove Remazol Brilliant Blue Dye From Aqueous Solution and Adsorption Isotherm Model Studies Noor A. Al-Khazali
Journal of Global Pharma Technology Volume 11 Issue 07
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Abstract

The adsorption of Remazol Brilliant Blue dye from aqueous solutions by using (Porcelanite- Melamine-Urea) (PMUC) as an adsorbent .The characterization of (PMUC) was done by using FTIR spectroscopy, X-ray diffraction (XRD), (SEM) scanning electron microscopy and (AFM) Atomic force microscopy. Different experimental data such as contact time, pH, adsorbent dosage and ionic strength were studied. The equilibrium experimental data were analyzed by Langmuir, Freundlich and Temkin isotherm models. Thermodynamic parameters such as change in free energy (ΔG°), enthalpy (ΔH°), and entropy (ΔS°) were also determined.Keywords: Adsorption, Porcelanite rocks, Remazol Brilliant Blue, Isotherms, Langmuir, Freundlich, Temkin.
The Effect of Moringa oleifera Extract as Candidate Prebiotic to Increase the Growth of Lactobacillus acidophilus and Lactobacillus plantarum Probiotics Widya Paramita Lokapirnasari
Journal of Global Pharma Technology Volume 12 Issue 11 (2020) Nov. 2020
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Abstract

Objectives: The potential of probiotics can be increased by adding prebiotics, which are substances that cannot be digested, but can be used by probiotics to increase their growth. Prebiotics generally consist of oligosaccharides. Moringa oleifera has potential as a prebiotic candidate. This study aims to prove the use of Moringa oleifera (M. oleifera) extract as a prebiotic candidate to increase the growth of Lactobacillus acidophilus (L. acidophilus) and Lactobacillus plantarum (L. plantarum) probiotics. Methods: This study consisted of 4 treatments and each treatment was repeated 5 times. The treatments consisted of: P0: 0% Moringa oleifera extract, P1: 0.1% Moringa oleifera extract (v/v), P2: 0.2% M. oleifera extract (v/v), P3: 0.3% M. oleifera extracts (v/v). The probiotic concentration is 1.5x108CFU/ml. Results: The results showed that there was a significant difference (p
Estimation of Some Trace Elements and Antioxidant Status in Breast Cancer Patients Undergoing Radiotherapy Abdul Rahman R. Mahmood
Journal of Global Pharma Technology Volume 10 Issue 06: (2018) June 2018
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Abstract

Breast cancer (BC) is the most prevalent tract cancer in the world, including Iraq. The classified breast tumors to benign, malignant, and radiotherapy. Cancer treatment depends on certain stages such as mastectomy then chemotherapy alone or with radiation therapy or endocrine therapy according to the prognostic features obtained from the pathology report. The present study included 100 females. The women were split into two groups, control group that consisted of 50 apparently healthy females and 50 patients with BC group who undergo the radiotherapy. The current study highlighted on some of the anthropometric measurements, including the oxidative stress index malondialdehyde (MDA), the concentrations of total antioxidant capacity (TAC), serum albumin (Alb), serum uric acid (UA), and finally the concentrations of copper (Cu) and zinc (Zn) as trace elements were measured as well. The results were compared to control. There was a significant variation in MDA and albumin when comparing patient group with control, while uric acid was statistically insignificant when comparing control group with patients group. Cu concentration was statistically high when compared with control group. On the other side, a significant decrease of Zn concentration of patients was observed compared to control group .In this study, the evaluation of these parameters maybe used as a helpful tool in treatment of breast cancer.Keywords: Breast Cancer, Malondialdehyde, Total antioxidant capacity, Copper, Zinc
Clinical Aspects of Tetanus in Bali, Indonesia mahadewa gde bagus tjokorda
Journal of Global Pharma Technology .
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Tetanus is well known for its significant effects to human body. It may cause neurological deficit, systemic symptoms, and mortality in worse cases. The aim of this study was to describe comprehensive clinical aspects of tetanus in Sanglah Hospital. Tetanus prevalence in Sanglah Hospital, from June 2014 - December 2015, were 29 cases. The majority of age was less than 60 years old, predominantly were male patients. All of tetanus cases were classified as moderate-severe general tetanus. We recommended DAKAR classification in order to determine prognosis of tetanus. Most prevalent symptoms were trismus, rigidity and muscle spasm. All patients were hospitalized in isolation ward. There were tendencies to use more than one kind of antibiotics. Metronidazole and cephalosporin were the most frequently used as they were recommended by other researchers. This research showed critical period of treatment for general tetanus were on 6-7 days of admission. Mortality rate of tetanus cases in Sanglah Hospital were 27.6%. Factors that associated with mortality were incubation periods, aspiration pneumonia, sepsis, high fever and opistotonus.Keywords: Tetanus, Prevalence, Symptoms, Treatment, Mortality.

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