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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
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Nanoemulsion Preparation, Identification and Evaluation Review Mustafa R. Abdulbaqi
Journal of Global Pharma Technology Volume 11 Issue 07
Publisher : Journal of Global Pharma Technology

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Abstract

Nanoemulsions consist of two immiscible liquids combined with emulsifying agents (surfactants and co-surfactants) in a thermodynamically stable, colloidal dispersion system, in order to form the same phase. Nanoemulsions have been thoroughly investigated as drug delivery systems. This review is aimed at providing comprehensive information on various techniques of nanoemulsion preparation and identification. There are two different methods for formulating nanoemulsions, the method of persuasion and the method of brute force. Different identification techniques for nanoemulsions include determination of trap efficiency, particle size, polydispersity index, zeta potential as well as characterization by differential scanning calorimetry, Fourier-transform infrared spectroscopy and transmission electron microscopy. Nanoemulsions are further assessed by studying in vitro release of drugs, in vitro permeation, stability and thermodynamic stability, shelf life, dispersibility, viscosity, surface tension, refractive index, percentage of transmittance, pH and osmolarity.Key words: Nanoemulsions, Nanoemulsion preparation, Identification techniques
Predictors of Quality of Life in Patients with Heart Failure: A Literature Review Ah. Yusuf
Journal of Global Pharma Technology Volume 12 Issue 09 (2020) Sept. 2020
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Abstract

Heart failure (HF) is a chronic disease characterized by reduce heart efficiency affecting patients’ quality of life (QoL). Patients with HF report lower QoL compared with general population and other patients with chronic disease. There are multidimensional factors affecting QoL. Therefore, it is important to identify factors that could be associated with changes in QoL to improve outcomes. The aim of this study was to identify significantly factors related to QoL in patients with HF according to the available literatures. The literatures were searched in appropriate database, using PICO framework, from January 2012 until August 2018. Eighteen relevant articles were found and reviewed. Factors that are significantly related to QoL in patient with HF can be grouped into 5 categories, i.e. physical factors include physical symptoms, physical activity, functional status, duration of HF, and multiple hospitalization; psychosocial factors include depression, optimism, exercise self-efficacy, and living independently; behavioral factors include self-care engagement, water and sodium restriction; spiritual factors include acceptance of illness and existensial well-being; and demographic characteristics include age, sex, education, economic and employment status. This review provides insight on potentially factors affecting QoL. Proper intervention in modifying those factors is expected to improve the quality of life. Keywords: Heart failure, Quality of life, Health-related quality of life, Predictors.
The Relationship between Employees’ Work Commitment and Organizational Policies (Housing and Urban Development Office of Chaharmahal and Bakhtiari Province) Meisam Jamalzadeh
Journal of Global Pharma Technology Vol. 9 Issue 7 : 2017
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Abstract

Today, organizations' attention to maximize the capabilities of their employees has substantially grown. However, it should be noted that employees do not necessarily apply all their capabilities to accomplish the objectives of the organization. One of the most important reasons for this is the lack or shortage of organizational commitment of the staff. Accordingly, this study strived to investigate the relationship between employees’ commitment and organizational policies in the Housing and Urban Development Office of Chaharmahal and Bakhtiari province. The research method is applied in terms of the type of research and is a survey method in terms of data collection method. To achieve the research objectives, among from 456 employees of the Housing and Urban Development Office of Chaharmahal and Bakhtiari province, 243 individuals were selected as the study sample. Using a researcher-made questionnaire, employees' commitment and organizational policies were assessed. In order to test the research hypothesis, LISREL software and the structural equation modeling analysis method were used. The results of the study indicated the relationship between different components of organizational policies such as role clarity and role conflict with organizational commitment of the employees.Keywords: Employees’ Organizational Commitment, Organizational Policies, Housing and Urban Development.
Efficacy of Dialectical behaviour Techniques (DBT) in Reduction of Anxiety of Students in Tehran- Iran Shahrbanoo Ghahari
Journal of Global Pharma Technology .
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Abstract

Background and objective: Dialectical Behavior Therapy techniques can be used as useful and effective method in reduction of many clinical symptoms. In this study, Efficacy of dialectical behavior therapy in reduction of   anxiety of students in Tehran City is investigated. Methods and materials: this study is in kind of empirical study with pretest and posttest design with control group. Statistical population in this study consists of all high school female students of Tehran (n=674) educating during academic year of 2015-2016. First, cluster sampling is used and 4 schools are selected from schools of Tehran and from each couple of schools, 2 classrooms were selected and the students with high score in Beck's Anxiety Inventory (BAI) were selected as sample. Then, 30 students were selected using random sampling method and were placed in two groups with 15 people in each group. Both groups fulfilled the BAI in basic step. Experimental group received 12 sessions’ intervention with dialectical behavior therapy techniques and control group remained in waiting list. Both groups fulfilled BAI again after the treatment. Obtained data are analyzed using MANCOVA. Results: obtained results from the study showed that Dialectical Behavior Therapy can affect reduction of anxiety of female students and mean values of both groups are significantly different from each other (p<0.01).Conclusion: Dialectical Behavior Therapy (DBT) techniques can lead to reduction of anxiety of female students.Keywords: Dialectical behavior therapy (DBT) techniques, Anxiety, Female students.
Biodegradable Chitosan Dyes for Clean Environment and Their Application as Alternative Green Dyes Shaimaa H Abdullah
Journal of Global Pharma Technology Volume 11 Issue 09: (2019) September 2019
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Abstract

This research aimed at preparing derivatives of natural polymer Chitosan (CS) carrying chromophoric chromatic groups, such as amine benzaldehyde groups (I, II, III) and aromatic azo dyes (I1-I5), (II1-II5), (III1-III4), which are characterized by their stability till the preparation of environment-friendly biodegradable polymers. The study identified polymers resulting from polymer (CS) interaction with three phenolic benzaldehydes and then the interaction of amine derivatives of these polymers with diazonium salts prepared simultaneously by some aniline in the infrared spectrum FT-IR, proton nuclear magnetic resonance, the X-ray spectrum (X-RD) and the change of physical properties.Keywords: Chitosan, Schiff Base, Azo Dyes, X-Ray, Chitin.
Nigella Sativa-Based Protection against Uterus and Ovary-Related Histological Damages Generated by Cimetidine in Mice Wafaa Sameer Abdullah
Journal of Global Pharma Technology Volume 10 Issue 08: (2018) August 2018
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Abstract

To generate protecting effects against the histopathological changes in uteri and ovaries in mice that are caused by cimetidine, this work was initiated using the aqueous suspension of Nigella sativa. In this experiment, 40 female mice were recruited that were randomly divided into 4 groups. Nigella sativa-cimetidine group (NCG) was given orally 1000mg/kg B.W of Nigella sativa-based aqueous suspension (NSAS) daily that was followed by administering cimetidine at 25mg/kg B.W. Nigella sativa group (NG) was administered orally 1000mg/kg B.W of NSAS daily. Cimetidine group (CTG) was exposed to 25mg/kg B.W of cimetidine daily. Control group (CG) received normal saline only. The experiment was run for 76 days. After the experiment was done, animals were sacrificed to obtain uteri and ovaries from all groups. These organs were subjected to histopathological-based processing and microscopically examination. The results of applying cimetidine alone in the CTG revealed harmful changes that interfered with the normal physiological activities in these organs that were ceased after using NSAS in the NCG. The study provides valued and important information about the use of Nigella sativa and its extracts in generating protection against the genital-based harmful changes induced by cimetidine.Keywords: Cimetidine, Nigella sativa, protection.
Sulforaphane and Bardoxolone (CDDO)-Induced Inhibition of Aflatoxin B1-Mediated Genotoxicity in Human Lymphocytes: Role of CYP3A4 and CYP1A1 Gene Expression Safa M. Abdulateef
Journal of Global Pharma Technology Volume 11 Issue 03
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Abstract

Real-time PCR used to investigate the ability of sulforaphane (SFN) and Bardoxolone (CDDO) on inhibition of aflatoxin B1 genotoxicity in Human lymphocytes in vitro. Real time PCR analysis carried out for AFB1 treated lymphocytes with/without SFN and CDDO separately to assess its effects on global transcription through monitoring gene expression variation among genes responsible for AFB1 biotransformation including those involving in AFB1 bio activation like CYP1A1 and CYP3A4, calibrated with B-actin gene. Lymphocytes incubated with 10 and 100ng/ml of AFB1 separately and simultaneously with two different anti-proliferative, anti-inflammatory agents (SFN and CDDO). Protective effect of SFN and CDDO required co-treatments with AFB1. Human lymphocytes incubated with 10 and 100ng/ml AFB1 mixed with 10 and 50µM SFN respectively for 2 hr., on the other hand lymphocytes incubated with 10 and 100ng/ml AFB1 mixed with 10 and 50µ M CDDO respectively for 2hr. CYP1A1 expressed more than CYP3A4 in human lymphocytes; Transcriptional repression for genes involved in AFB1 bio activation was showed after treating with SFN and CDDO. SFN able to inhibit CYP1A1 expression more than CDDO, SFN inhibit CYP1A1 to (~4.32) fold comparing with separately AFB1 treated cells  (P<0.05*).
Implementation Development Of Work Climate To Better Worker Productivity Employee In Stikes Hang Tuah Surabaya Dedi Irawandi
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
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Abstract

Productive nurses are produced from qualified educational institutions. To achieve optimal work productivity growth required several supporting factors, one of them is the harmonious working climate.  This work purports to obtain a photo of the workplace climate and its relationship to employee productivity. The dimensions of the employment climate in search are (1) the concept of the psychological dimension of employees; (2) the structural proportions of employees; (3) social dimensions of employees; (4) employee bureaucratic dimension.  This research uses a quantitative and qualitative approach. The Result of research (1) Worker productivity at Stikes Hang Tuah Surabaya shows good work productivity (58%), unfavorable (42%), (2) Psychological dimension related to work productivity; (3) Structural dimension is not related to work productivity; (4) Social dimension related to work productivity; (5) The bureaucratic dimension is not related to work productivity. Recommendations for the management, need to be developed further standard performance of a team sharing development and application of a fair reward system for the achievers and penalties for the violators
Spectrophotometric Study of Dyes for Dye Sensitized Solar Cell (DSSC) Moneer K. Mohsen
Journal of Global Pharma Technology Volume 09 Issue 12
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Abstract

This paper described the absorption spectra of some dyes (N719, N3, N749 and SQ2) were measurements as sentesizeed materials for dye- sensitized solar cell (DSSC). It was used commercially dyes namely N719, N3, N749 and SQ2. All samples prepared as solutions at different concentrations (10-4, 10-5, 10-6M), by using ethanol as a solvent, exclude SQ2 used methanol as a solvent. The samples were evaluated spectrophometricaly;UV-Vis spectra results proved that there were two peaks for (N719, N749, and N3) at (390and530nm), (430and626nm) and (390and540nm), respectively. While SQ2 dye showed one peak at 650nm. The calibration curves for these dyes involved were created, and the molar extinction coefficient was calculated for samples involved. The molar extinction coefficients for N719, N749, N3 and SQ2 were determined at previous peaks, and its values were(16406 M-1cm-1and 14135M-1cm-1),(10000 M-1 cm-1and 9329M-1 cm-1),(11974 M-1 cm-1and 10032 M-1cm-1)and(22384 M-1 cm- 1)1respectively,which it was found that SQ2 have  high molar coefficients than previous dyes which was important in photon absorption and  DSSC device photocurrent increase.Keywords: Dye, Absorption, Molar Extinction Coefficient, Dye sensitized solar Cell.
The Effect of an E-Learning Design by Ruffini Model in Learning Passing and Lay Up Scoring Skills in Basketball for Female Students Hayder S. Mohseen
Journal of Global Pharma Technology .
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Abstract

The present study objectives to develop a pedagogical design in the Ruffini model for the correction of lay-up and the passing of basketball for female students. Learning the impact of the instructional design in the Ruffini model teaches you how to shoot the lay-up and the passing of the basketball for female students. The researcher used the experimental approach of two equal pretest and other measurement sets to fit the nature of the research problem and objectives. Researchers have used the experimental approach of two equal pretest and self-measurement sets to fit the nature of the research problem and objectives. The sample of research (30) was in the experimental group and the same as in the officer, and educational modules were prepared according to the instructional design of the Ruffini model for the skills examined and the main experience was applied to female students for 8 weeks with two educational units per week and with a time of capacity (90) Minutes for one educational unit. The design of the Ruffini model has contributed to the training of the passing and correction of the ladders of the first stage students in the experimental group. One of the most important findings of the researchers is that the design of the Ruffini model has contributed to the learning of the passing and correction of the foot ladders of the first stage students in the experimental group.Keywords: E-learning designs, Ruffini model, Shoot lay-up, the passing and basketball.

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