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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
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Factor Analysis of Patient with Hypertension on Self-Regulation Based on Self-Belief Riza Fikriana
Journal of Global Pharma Technology Volume 11 Issue 08 (2019) Aug. 2019
Publisher : Journal of Global Pharma Technology

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Abstract

Objective: The purpose of this study was to analyze the factors that influence self-regulation based on the self-beliefs of hypertension patients. Methods: The design of the study used observational analytics with a cross-sectional study approach. The sample size consisted of 108 patients with hypertension in health centers in Malang Regency, East Java, Indonesia. The independent variables were physical activity, food consumption, medication adherence, control in health care and stress management. The dependent variable was self-regulation. Data were collected using a questionnaire tested for validity and reliability. Logistic regression was used to analyze the results. Results: Age (p = 0.014) and support of health workers (p = 0.004) had an effect on the self-regulation of food consumption. Age (p = 0.008), gender (p = 0.006), family history (p = 0.004), family support (p = 0.014) and health insurance (p = 0.028) had an effect on the self-regulation of medication adherence. Age (p = 0.022) affected the self-regulation of control to health services. Peer support (p = 0.008) was significantly associated with stress management. Conclusion: The consolidation of social support and health services is important to improve self-regulation based on self-beliefs in patients with hypertension.Keywords: Self-regulation, Confidence, Hypertension.
Contamination of Tea and Coffee by Ochratoxin A in Hilla City, Iraq Mohammad J Al-Jassani
Journal of Global Pharma Technology Volume 10 Issue 06: (2018) June 2018
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Abstract

Analysis of several ground coffee and black tea samples sold in Hilla city market for Ochratoxin A (OTA) contamination. Ten of the most common Black tea and 10 Coffee samples were collected from the local ‎market. OTA was extracted following a standard technique then subjected to TLC analysis. All tested tea samples were found contaminated with OTA (100%). Five (50%) of coffee samples were found contaminated with OTA. This might indicate of bad quality tea have been ‎imported and/or with bad processing and packaging.‎ Iraq as a big importer and consumer of black tea is appeared ‎subjected to a high danger of OTA contamination. A very urgent concern need to be ‎directed and OTA safety level determination using HPLC for both imported and consumed tea ‎and coffee before marketing.Keywords: Coffee, Tea, Ochratoxin A, TLC.
C-Reactive Protein a Suitable Marker for Heavy Metal Toxicity: A Comparative Study for Two Freshwater Fish Species Response to Cadmium Alaa J. Hassan
Journal of Global Pharma Technology Volume 9 Issue 10
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Abstract

The present study estimate some blood parameters including, total and differential white blood cells (WBCs) count, red blood cells (RBCs) count, hemoglobin (Hb) level and packed cell volume percentage (PCV%), as well as the concentrations of serum total protein and C – reactive protein (CRP) in two species of Iraqi freshwater fishes (CyprinusCarpio and Hypophthalimchthyes molitrix) exposed to two concentration of cadmium (cd) (0.5 and 1) pep. Fishes exposed to cd in glass basins  for 7 and 14 days with five replicate for each treatment and control groups .Results: The results showed that there was a significant differences (p<0.05)  in the total WBCs count, monocytes (MON),granulocytes (GRA) and RBCs between individuals of both treated species in each period and treatment , but there was a significant decreases (p<0.05)  for this parameters in  treated silver carp group  compared with silver control group, furthermore , there was a significant decrease PCV% in silver fishes treated with cd , as well as there was a significant decrease in the level of Hb  for both  treated species  compared with healthy subject . The data revealed that there is a significant differences (p<0.05) in the concentration of total serum protein between individuals of both treated species in each period and treatment, but there was a significant decrease (p<0.05) in the level of this parameter in treated H. molitrix groups compared with control group, furthermore, the level of CRP revealed that significant increase in different periods and level of pollutant in both treated fishes groups compared with healthy subject. Conclusions:  The results displays that there is a significant differences (p<0.05) in the levels of blood parameters between treated species of fishes, and H. molitrix fish was more sensitive to cd in comparison with treated C. carpio and control group, also there was a significant difference in the levels of total serum protein and CRP in treated fishes compared with control groups.Keywords: Cyprinus Carpio, Hypophthalimchthyes molitrix, Cadmium, Hematology, Immunology
EFFECT OF WATER STRESS ON GROWTH, METABOLIC ACTIVITIES OF WITHANIA SOMNIFERA-AN IMPORTANT PHYTOCEUTICAL PLANT: AMELIORATIVE EFFECTS OF VAM Haripriya M
Journal of Global Pharma Technology Volume 02 Issue 03: (2010) March 2010
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Abstract

A greenhouse experiment was conducted to study the influence of arbuscular mycorrhizal (VAM) fungus inoculation on Withania somnifera, a medicinal plant under water stress. Root and Shoot lengths, total plant dry and fresh weights, root and shoot dry and fresh weights, number of leaves, leaf area, chlorophyll content, lipid content, carbohydrate content, DNA and RNA content were evaluated at 12 days, 20 days and 28 days after stress. Study of all the above parameters was made in four treatments T1 (control), T2 (mild stress), T3 (severe stress), T4 (severe stress with VAM treatment). We observed in all the characteristic features of the study, that there was a decrease in them during severe stress conditions compared with those of control plants. The VAM treatment helped the plants to with stand the water stress and to yield maximum biomass.Keywords: Water stress, growth, biochemical aspects, Withania somnifera.
Correlation between Body Mass Index and Cartilage Oligomeric Matrix Protein Levels in Woman with Postmenopausal Symptomatic Osteoarthritis IGN Wien Aryana
Journal of Global Pharma Technology Volume 11 Issue 04.
Publisher : Journal of Global Pharma Technology

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Abstract

Background: Measurement of serum cartilage oligomeric matrix protein (sCOMP) concentration is expected to be new approach  for osteoarthritis early detection. Osteoarthritis has been linked to obesity as its risk factor. This study aimed to determine relationship between BMI and sCOMP in woman with symptomatic osteoarthritis. Methods: : A cross-sectional study was done using consecutive sampling. The study population comprised of female patients age 50-70 y.o who had menopause since last 1 year and symptomatic knee arthritis. Osteoarthiris were comfirmed by genu imaging. sCOMP concentration were determined in Clinical Phatology Laboratorium of Sanglah Hospital using ELISA technique. The body mass index was calculated using the standarized formula. Correlation test was used to determine the correlation between body mass indexes with sCOMP level. Results: From total of 68 participants, the mean age was 73.66 (SD 9.356), the mean BMI was 21.97 (SD 4.66), and the mean sCOMP concentration was 7.935 (SD 10.11). Significant correlations (p <0.01) occured for this sample. However, Spearman’s rho was quite low (r = -0.382), indicating only weak correlations. A higher BMI was associated with lower sCOMP concentration. Conclusion: The results prove the relationship between BMI and sCOMP concentration. Further research is needed to reveal causality between both variables.Keywords: Osteoarthitis, Women, BMI, sCOMP concentration.
Nanoparticles Suspensions as Optical Power Limiting Synthsization and Characterization Gofran Hadi
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
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Abstract

In this study, the investigation of the nonlinear and optical properties of nanoparticles (AgNPs) in distilled water with gold nanoparticles (AuNps) was investigated. The non-linear absorption coefficient of nanotubes was measured by Z-scan. Nanonuclear AuNps with AgNPs under exposure to nano-laser pulses at 532 nm as well as 405 nm and 650 nm. The results showed that nonlinear diffusion can increase the performance of the optical marker. A theoretical analysis is proposed Investigate non-linear behavior observed from AgNPs with AuNPs. Shows that the dispersion of non-linear light occurs at high intensity because of the inverse refractive mismatch between silver nanoparticles with gold and water. TheZ- scan experimental data were provided with the proposed theoretical model, allowing the extraction of nonlinear absorption coefficients and linear and nonlinear propagation coefficients for AgNP suspension with AuNPs.
Monitoring (Biodiversity) Aquatic Plants of Iraqi Marshland Hadeel Radawi Al-Newani
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

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Abstract

The study was conducted during December 2014 –December 2015 in ten mainly stations from Iraqi marshlands since been recorded dominated types of aquatic plants in study sites .Results showed that high intensity for aquatic plants  all months was observed at a rate of 73 % Typha sp. , followed Phragmitesaustralis impressive 65%  then Ceratophyllumdermersum 33 % less abundant for being non-indigenous , statistical results highest value to the standard appearance of species Mean±SD (0.999± 0.013 ) (0.480 ± 1). Evaluation of species of aquatic plants in marshes communities response to the change of climate, focusing on the type it , submerged ,emergent and floating and depending on differences and similarities with responses to factor , temperature , O2 , CO2 exposure, level rise water and other expected environmental alterations with natural weather in the region .Advantages environmental climate have an important influence on plant diversity of Iraqi marshes. Based on environmental factors ten ecological regions with the specific plant which is located   climate factors interact to plant influence distribution   and they play an important role in creating ecological biodiversity of Iraq.Keywords: Iraqi marsh, Bio monitoring, Distribution Aquatic plants.
Introduction of Red Soil (Ocher) of Hormoz Island as a Natural Adsorbent to Removal of Cadmium from Aqueous Solutions Hamed Biglari
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

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Abstract

Due to teem and low cost ocher red soil in Hormoz Island (south of Iran), this study was conducted to investigate the efficiency of red soil on adsorption of cadmium from aqueous solutions. a series of steps for adsorption of cadmium on ocher were conducted which included the ocher selection/preparation, determination of chemical and physical characteristics of adsorbent, preparation of cadmium stokes, determine the equilibrium time, the effect of cadmium concentration, adsorbent dose, the effect of environmental factors (pH and temperature), and determine the adsorption kinetic and isotherm. raw ocher had better adsorption efficiency than processed type (74.33% vs. 35%), the main component of adsorbent was Fe2O3 (59.58%). The optimum conditions as dose, pH and temperature which respectively were as (20 g/L; 10; and 35 oC), the adsorption reach to 96%. The study of isotherm and kinetics showed that Cd adsorption on raw Ocher is more fitted to Freundlich isotherm and pseudo second order models. natural ocher of the island of Hormoz would be appropriate to remove the heavy metal, as no need to processing it is economical to use. As temperature has positive effect on Cd adsorption on ocher, this adsorbent can act more effective in hot climate.Keywords: Cadmium, Red soil, ocher, adsorption, Hormoz Island, aqueous solutions
Scanning Electrochemical Microscopy: Activity Mapping of Ascorbate Oxidase Immobilized onto Glass Surface Ali Esmail Karim
Journal of Global Pharma Technology .
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Abstract

Glass-microscope slides were covalently modified with a common coupling agent of 3-aminopropyltriethoxysilane (APTES) by silanization reaction. After activated with glutaraldehyde, ascorbic oxidase was immobilized on microscope slides. The modified slides were examined before and after activation with glutaraldehyde by Fourier transform infrared spectroscopy (FTIR).The scanning electrochemical microscopy images of modified microscope slide have been used to detect the presence of the ascorbic acid oxidase as its confirm the direct electron transfer process in feedback mode experiments and provide that the enzyme is evenly immobilized on the modifies slide.Keywords: Catalytic activity, Ascorbate oxidase, Surface modification, APTES, Glutaraldehyde, SECM.
Effect of Chitosan-Lemongrass Essential Oil-Xanthan Gum Coating on the Shelf Life of White Mushroom (Pleurotus ostreatus) N. P. Minh
Journal of Global Pharma Technology Volume 11 Issue 07
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Abstract

Mushrooms (Pleurotus ostreatus) are rich in nutrients, such as minerals, vitamins, amino acids, carbohydrate. They have thin and porous epidermal structure with high respiration rate comparing to other fruits and vegetable. They are highly perishable and lose quality very quickly right after harvesting. Mushroom shelf-life is usually short under normal handling and distribution. Therefore, mushrooms must be taken care to maintain their freshness and commercial value. Chitosan has been found to be non-toxic, biodegradable, biofunctional, biocompatible, antimicrobial and antifungal activities. Lemongrass essential oil has stability properties of water vapor permeability of films made based on chitosan. Xanthan gum is one biopolymer promising for food packaging. Our present research focused on the effect of chitosan-lemongrass essential oil-xanthan gum coating on the shelf life of white mushroom (Pleurotus ostreatus). Results revealed that a composite of chitosan-lemongrass essential oil-xanthan gum coating (2.0%: 2.5%: 2.0%) could maintain the quality and extend the shelf-life of mushroom for 7 days of storage.Keywords: Pleurotus ostreatus, chitosan, lemongrass essential oil, xanthan gum, coating, shelf-life

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