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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
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Estimation Some Heavy Elements in Drinking Water in Baghdad City / Al Rusafa Salem Saleh Al-Tamimi
Journal of Global Pharma Technology Volume 11 Issue 03
Publisher : Journal of Global Pharma Technology

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Abstract

This study aimed to identify the drinking water content of bacteria, yeast, mildew colon bacteria and heavy metals in Baghdad city /Al-Rusafa. Fifteen water samples were collected from different cities including (Al-Karrada, Al-Dora, Palestine street , Obeidi, Zafaraniyah, Kamaliyya, Zayouna, Adhamiya, Ur district, Talbiya, Jamila, Al-Bnouk district, Shaab, Baladiyat, Al- Mustansiriya district), Heavy elements were estimated in these samples, which including (Chrome Co, Lead pb, Copper CU, Cadmium Cd and Nickel Ni), Some microbiological tests were performed including detection of the total number of bacteria, Yeasts and Mildew and colon bacteria by using Bac Trac device. Results showed that heavy elements concentrations ranged from 0.1000-2.787 ppm for chrome element and 0.021-0.338 ppm for Lead, 0.0096-0.2461 ppm for copper, 0.2108-0.3308 ppm for Cadmium, and 0.0065-0.6556 ppm for Nickel. Clearly it was shown that concentrations of lead, chrome and cadmium higher than the Iraqi standard specifications specified No. 417 on 2009 related with drinking water. The results of this study showed that all samples were free from all microbial content and this result were matching by the Iraqi standard specifications above mentioned.Keywords: Iraqi drinking water-Microbial content-heavy metal.
Corrosion Inhibition Efficiency and Adsorption of Azo Schiff Base Chelate Surfactant at Carbon Steel in Hydrochloric Acid Interface Mohammed Abdulhussin Enad
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
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Abstract

The aromatic Schiff base with azo linkage (CHMB) has been synthesized and characterized by FT-IR, 1H NMR and 13C NMR spectroscopic techniques. The compound (CHMB) has been evaluated as carbon steel corrosion inhibitor at different concentrations (0.1, 0.5, 1 and 5 mM) and different temperatures (298-318 K). The corrosion inhibition efficiency was studied by Potentiodynamic polarization. The effects of concentration and temperature on the inhibition efficiency were studied by Potentiodynamic polarization measurements, the results showed that increasing concentration of (CHMB) increases the inhibition efficiency while increasing the temperature decreases it, the highest corrosion inhibition efficiency, 93.58% was recorded with 5 mM of CHMB at 298 K in 1 M HCl. The adsorption process was found to obey Langmuir isotherm, and the adsorption thermodynamic parameters were studied.Keywords: Carbon steel, Corrosion inhibitors, Azo, Schiff base, Organic inhibitors.
Some Natural Plant Extracts can be used as Leishmania Stains Nidaa Mohammed Sulaiman
Journal of Global Pharma Technology .
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Abstract

Visceral leishmaniasi is a chronic disease caused by Leishmania donovani. Staining method is an effective way for identification of parasites by using synthetic or natural dyes. In this study Morus nigra, Punica granatum and Quercus infectoria extracts were used as natural dyes to investigate their staining activity to stain L. donovani promastigote in comparison with geimsa stain. Results: the three extracts showed a good staining ability, M.nigra was the best followed by P. granatum and Q. infectoria. Conclusion: according to the results, dying with natural dyes is cheap, safe and could be alternative for synthetic dyes.                                   Keywords: Natural dyes, Synthetic dyes, L. donovani, Extrac.
HEALTH AS A CORE CHARACTERISTIC OF HUMAN EXISTENCE A.G. Madzhuga
Journal of Global Pharma Technology Volume 08 Issue 08
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Abstract

Nowadays the humanity has reached the limits of its physical existence and such unprecedented impairment of harmonious relationships between nature and mind that it is impossible to keep neglecting natural biological foundations of a human body anymore, as split human integrity inevitably leads to the loss of his essential certainty and his disappearance.
Salivary Alpha Amylase Enzyme and Calcium Changes with the Age and Their Effect on Dental Caries Haider A Naji
Journal of Global Pharma Technology .
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Abstract

Introduction: Saliva is a clear, slightly acidic oral secretion, mainly produced by the major and minor salivary glands. Saliva plays an important role in the oral health and the levels of its constituents alter with age [1]. The study comprise α-amylase enzyme and Ca in saliva , and follow the changes occured in their levels according to age changes, and explain the effect of these changes on dental and periodontal tissue health. Materials &Methods: Ninety samples of saliva were collected from different age groups, which are divided into three study groups; group I (20-35 years), group II ( 36-50 years) and group III (51years and above) Amylase Alpha I and Calcium are analyzed by ELISA technique. Results: Results show that Mean ± S.D of Amylase Alpha I of the Age group I is (110.35±66.42), while that in the age group II is (71.19±58.53) and in age group III is (85.87±56.62). The level of α-amylase I among study groups is decreasing with the age, but not significant (P≥0.05). For salivary Ca, Mean & S.D of salivary calcium  for the age group I  is (6.04±1.87), Mean & S.D for age group II is (5.67±0.79), and for age group III is (8.07±0.56) which shows significant increasing with the age (P≤0.05). Conclusion: The level of salivary Amylase Alpha I enzyme is decreasing with age, therefore there is less adhesion of bacteria to tooth surface, while the level of salivary Ca, is increasing with age, which aid in remineralization process and reduce development of dental caries with age.Keywords: Saliva, Α-amylase enzyme, Ca.
Characterizations of Lavender Flowers Extracts and Study of their Effects on Peroxidase Activity and Some Microorganisms Falah S. Al-Fartusie
Journal of Global Pharma Technology Volume 11 Issue 07
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Abstract

Herbal medicinal plants have been used traditionally to treat diseases in addition to commercial use. Therefore, this study is designed to extract the most important components of lavender flowers herbal and study their biological activities against some important species of bacteria and fungi as well as against peroxidase activity. The study also includes a description of Lavender flower extract using UV-Vis and GC-MS techniques. In this study, three extracts (ethanolic, cold aqueous and hot aqueous extracts) were prepared by maceration (1gm/50ml solvent). UV-Vis spectroscopy was revealed peaks embedded in a significant functional range (200-400) nm, which may be attributed to unsaturated functional groups and hetero atoms (S, N, O). The results showed an inhibitory effect of the cold and hot aqueous extracts on the activity of peroxidase. Kinetic study demonstrated that the cold extract caused a non-competitive inhibition while hot extract caused a mixed type inhibition. The kinetic parameters obtained by Lineweaver-Burk plot, in the presence and absence of lavender extracts respectively, indicated that the Km values were (0.0007, 0.001) mM while Vmax values were (95.23, 125) U/L for cold aqueous extract, while the Km values were (0.0028, 0.003) mM, and Vmax values were (80.64, 112.5) U/L for hot aqueous extract. Antibacterial and antifungal effects against isolates in our study showed that ethanolic extract is more potent than aqueous extracts which could be predominantly the result of highly account of active phenolic compounds that presence in Lavender herbal ethanolic extract. The results of the current work support the traditional use of the studied plant and suggest that some botanical extracts, particularly ethanolic extract, have compounds with antibacterial properties that can be used as antibacterial agents in new drugs to treat infectious diseases caused by pathogens. The most effective extracts can be subjected to therapeutic antibacterial isolation and further medical evaluation.Keywords: Lavender; GC-MS; UV-Vis; Peroxidase; Antibacterial; Antifungal.
A Midwife: Professional Ethics in Midwifery Practices, Managing Pregnancy and Childbirth Complications, and Legal Rights for Nursing Mothers Ayesha Hendriana Ngestiningrum; siska diana sari; Rizka Rizka; Taadi Taadi; Sofyan Wimbo agung Pradnyawan; Sigit Sapto Nugroho; Dewi Iriani
Journal of Global Pharma Technology Volume 12 Issue 09 (2020) Sept. 2020
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Abstract

This study aims to discuss a midwife as a health professional, professional ethics in midwifery practices, the management of pregnancy and childbirth complication, and legal rights for nursing mothers. This qualitative research utilizes interview as a main instrument. The data are collected from interviews conducted with: 1.) pregnant women who gave premature birth, 2.) nursing women and families supporting breastfeeding program, and 3.) Public Health Office staffs. The study reveals that legal ethics between midwives and patients is significantly crucial. There is a need for effective communication between midwives and patients. Patients have the right to obtain information as clearly as possible and midwives also have the right to get the trust of patients to perform medical procedures without any interventions. In addition to the aforementioned result, this study reports that there is pregnancy and premature childbirth complication. It is a maternal health issue occurred during pregnancy causing premature birth. This study also highlights a breach of guarantee to nursing mothers who breastfeed up to 2 years of age. The results of study conclude three points. First, it reports informed consent. It is a process for getting permission before conducting a healthcare intervention on a person, or on disclosing personal information. Second, legal practice regulating rights for nursing mothers and its legal sanctions for someone who prohibits breastfeeding for working women or health workers who provide formula milk to newborns without medical indication. Third, the authorized party will conduct an investigative audit of cases of complications of pregnancy and childbirth that cause infant mortality.
Relationship between Thyroid Hormones and TSH, FSH, LH, LH/FSH Ratio, Prolactin and Testosterone Hormones in Infertile Patient Women with Hyperthyroidism in Reproductive Age Dalal Abdul Hussain Kadium
Journal of Global Pharma Technology Volume 10 Issue 05: (2018) May2018
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Abstract

Our   work  involved  studies  for  levels of thyroid  hormones (Triiodothyonine T3,Thyroxin T4) and thyroid stimulating hormone   (TSH),follicular stimulating hormone(FSH), luitienzing hormone(LH), prolactin(PRL) and testosterone hormone LH/FSH ratio  in infertile patients women with hyperthyroidism and sanitary fertile women and to find the relationship between thyroid  hormones (T3 ,T4) and TSH, FSH, LH, PRL and testosterone hormones and LH/FSH ratio, and correlation of TSH with T3,T4, FSH, LH, PRL and testosterone hormones and LH/FSH ratio in sterile women with hyperthyroidism in reproductive age. (60) sterile women with hyperthyroidism with age (19-41) years old and body weight (65. 60 ±  0.20 kg ) who recalculated Endocrine unity of Teaching Al-Sadr hospital in Al-Najaf Al-Ashraf Governorate from  1/ 9 / 2015 to 1 / 10 / 2016  , patients women group was compared with (30) fertile non- patients women with age(19-41) years old and body weight (72.35 ±  0.42 kg) as control group. The results pointed to a significant increasing(P<0.05)in levels of T3,T4, LH, PRL , testosterone  and LH /FSH ratio, while a significant decreasing (P<0.05) was in TSH and FSH levels in sterile patient women with hyperthyroidism when compared with control group, and there was a positive significant (P<0.05)correlation between T3,T4 and LH,PRL , testosterone and LH/FSH ratio  , while the relationship was negative significant (P<0.05)between T3,T4 and TSH and FSH in sterile patient women    and the results showed a positive significant(P<0.05) relationship between TSH and FSH, while there was a negative significant(P<0.05) correlation  between TSH and  T3,T4, LH, PRL , testosterone and LH/FSH ratio in sterile women  patients with hyperthyroidism.Key words: Thyroid hormones, Infertility, Hyperthyroidism, TSH, FSH, Prolactin.
The Effect of 12 Weeks of Using Stability Ball in Working Environment on the Intensity of Pain and Disability in the People with Chronic Low Back Pain Jafar Ketabchi
Journal of Global Pharma Technology .
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Abstract

Introduction: low back pain is common among the employees who sit at the table for long hours. Comparing to sitting on office chair, sitting on stability balls causes activation of the core muscles of the body. Increasing the activity of core muscles in the central part of the body causes the increase of stability in Lumbo-pelvic-Hip complex which can be efficient in improving the pain, signs and symptoms of the patients with chronic low back pain. The objective of the present study was the transitional use of 12 weeks of stability ball instead of office chairs on pain indexes and disability in the patients with chronic low back pain. Material and methods: 28 men suffering from chronic low back pain (mean± standard deviation of age 4/2±5/39،BMI,  9/1±2/24) were selected to take part in the study through convenient method. The participants of the present study used stability ball for 12 weeks instead of office chair during some hours of their working (maximum two hours) at the office. The pain intensity and disability of the subjects were measured through applying QUEBEC and OSWERTRY questionnaires. Dependent sample t-test was used at 0.05 levels to analyze the data. Findings: a significant difference was observed in the relationship between pain intensity and disability in the participant people (P<0.05). The mean of pain intensity and disability in the people participating in the pretest were 26.4±5.0 and 24.2±5.4 respectively. After administering therapeutic protocol, the mean of pain intensity and disability decreased to 18.6±4.7 and 21.2±4.7 which showed an improvement of 29% and 12% in the pain intensity and disability in these patients. Conclusion: sitting on stability ball leads to more activation of core muscles of the body especially deep stabilizers in this part. Activating deep stabilizers in the core part leads to the improvement of the condition of patients suffering from chronic low back pain. According to the results of the current study, sitting on stability ball instead of office chair in working hours can cause more activation of core muscles. Therefore it is recommended to use stability balls instead of office chairs. although just the improvement of working environment cannot lead to the treatment and improvement, so making such changes along with other therapy modalities can cause more effectiveness on the condition of the patients suffering from chronic low back pain.Keywords: Chronic low back pain, Stability ball, Quebec questionnaire, Core stability, Oswertry questionnaire.
Corrosion Protection and Biological Activity Studies for Electrochemical Polymerized Poly (N-benzothiozolyl tetrahydrophthalamic acid) on Stainless Steel Alloy Mayasa I. Ali
Journal of Global Pharma Technology Volume 11 Issue 09: (2019) September 2019
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Abstract

The present work reports the electrochemical synthesis of poly (N-benzothiozolyl tetrahydrophthalamic acid) on stainless steel 316 (S.S) which acts as working electrode by using electrochemical polymerization technique. The formed polymer film was characterized by Fourier Transform Infrared Spectroscopy (FT-IR) and Atomic Force Microscope (AFM). Corrosion protection tests for coated and uncoated S.S with polymer film were studied in 0.2 M of hydrochloric acid (HCl) solution by followed Tafel and potentiodynamic procedures. Kinetic and thermodynamic of activation parameters (Ea, A, ΔH*, ΔS* and ΔG*) were calculated. Also, investigations the effect of the synthesized polymer on some strain of bacteria a gram positive bacterium which is Staphylococcus aureus (Staph.Aure) and negative bacteria which is Escherichia coli (E.Coli). In addition the polymer film was modified with nanomaterials which are (ZnOn (nano) and Graphene).Keywords: Electrochemical polymerization, Conducting polymer, Stainless steel, Anticorrosion, Antimicrobial activity

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