cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
I Wayan Sudarsa
Contact Email
sudarsa@unud.ac.id
Phone
-
Journal Mail Official
globalpharmatechnology@gmail.com
Editorial Address
India
Location
Kota denpasar,
Bali
INDONESIA
Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,438 Documents
 240   241   242   243   244 
PHYTOCHEMICALS AND ANTIMICROBIAL STUDIES ON COSTUS SPECIOSUS Dash, Deepti Prangya; Mohanty, Rajashree; Ray, Jassaswi
Journal of Global Pharma Technology Volume 16 Issue 12 (2024) Dec. 2024
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The aim of the present study was to investigate antimicrobial activity of methanolic extract of Costus Speciosus (CS). The percentage yield and physical status of the methanolic leaf extract (MECS) and chloroform (CSC) and aqueous fractions Costus Speciosus (CS) are showed. The antibacterial activity of a compound is expressed in terms of its ability to inhibit the growth of bacteria in nutrient broth or agar media. The bacterial growth inhibition can be measured by two methods (Cup plate method and Serial dilution method ) . Nutrient broth has been used for the preparation of inoculum of the bacteria and nutrient agar is used for the evaluation of antibacterial activity. All the Extracted compounds (BMC & BMQ), were found to be effective antibacterial agents. Antifungal activity evaluation against C. Albicans showed that compound BMH also did not possess significant antifungal properties. The study confirms that Costus Speciosus (CS) and all possess antimicrobial activity with different potency against variety of selected microorganisms. The differentiating activities of these extracts encourage developing an ovel broad spectrum antimicrobial herbal formulation in future. Costus Speciosus (CS), Antimicrobial Activity, Antifungal Activity, MECS, BMC & BMQ, BMH, Albicans.
PREVALENCE OF HELICOBACTER PYLORI IN OBESE PATIENT Altaee, Mohammed J.; Mohammed, Bilal; Jasim, Ahmed S.; Abdulkadhm, Hasanin
Journal of Global Pharma Technology Volume 16 Issue 12 (2024) Dec. 2024
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Helicobacter pylori is a widely recognized pathogen that exhibits a high prevalence among the global population. The infection caused by H. pylori poses significant health risks due to its association with various gastrointestinal disorders, including gastric ulcers, duodenal ulcers, chronic gastritis, and gastric carcinoma. The regulation of gastric hormones, such as ghrelin and leptin, plays a crucial role in energy homeostasis. Ghrelin, secreted by P/D1 cells in the stomach during periods of hunger, stimulates appetite and promotes food consumption. Conversely, leptin, released by P cells in the stomach and adipocytes after food intake, reduces appetite and fosters a sense of fullness. Individuals infected with H. pylori tend to have lower plasma levels of both ghrelin and leptin compared to those who are not infected. Consequently, the reduced serum leptin levels can delay the sensation of satiety during meals, leading to increased energy intake and a potential development of obesity. Aim: Our study has been proposed and structured to achieve the below objectives: Prevalence of H. pylori associated with overweight. Presence or absence of some clinical signs among patient. Prevalence of infection among age group. Methods: Blood seem were collected from 30 person during the period from February to April 2023 and both gender were participate in this study with age ranging from 20-50 years old.Blood tests were used to measure the antibodies against H pylori. The sample were collected and small amount of it applied in to well In the test line area, anti-human IgG is rendered immobile. Following its addition to the device's specimen well, the specimen reacts with the test's H. pylori antigen-coated particles. This mixture interacts with the immobilized anti-human IgG and migrates chromatographically over the course of the test. A colored line will show up in the test line region, signifying a positive result, if the samples contain H. pylori antibodies. A colored line indicating a negative result won't show up in this area if the specimen is devoid of H. pylori antibodies. To act as a methodical. Result: Our study shows that Middle age group were the highest percentage among other age group (35 %). In another hand the overweight patient suffering from H. pylori infection constitutes about 36.7 %. Keywords: Helicobacter Pylori, Obese Patient, Infection.
AN OVERVIEW ON DOSAGE FORM: SUPPOSITORY Jain, Anvesh; Panwar, Mangal Singh
Journal of Global Pharma Technology Volume 17 Issue 01 (2025) Jan 2025
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

In this article we converse about various aspects of suppositories such as their introduction, formulations and therapeutic applications. Suppositories are those type of dosage forms that used to provide medication via the vaginal and rectal routes. Before the invention of suppository, liquid enema was used. Enema’s has a big disadvantage that it leaks out of the cavity where it is inserted. Therefore an alternate method of medication was needed and thus suppository was invented. Suppositories can be described as semi-solid dosage form to provide medications via rectal, vaginal routes where they will melt or dissolve and deliver localized or systemic action. Suppositories are preferred over other dosage form because it comes in different shapes and sizes. Suppositories are one of the very convenient modes for drug delivery. In this article we discuss the fundamental components of suppositories including suppository bases, along with the methods of preparation of suppository. This article also targets to fabricate descriptive information about the advancement of suppositories such as, Bi-layered Suppositories, Hollow Suppositories, Effervescent suppositories, etc. Keywords: Suppositories, Types of Bases, Methods of Preparation, Advancement in suppositories.
BIOLOGICALS AND BIOSIMILAR: ADVANCING HEALTHCARE THROUGH INNOVATION AND ACCESSIBILITY Pal, Pradeep; Chorasiya, Anjali; Jawani, Akanshag; Rathore, Chalsy; Panwar, Mangal Singh
Journal of Global Pharma Technology Volume 17 Issue 02 (2025) Feb. 2025
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

“Biologics” considered one of the fastest growing sectors of the pharmaceutical industry; “Biologics” have introduced many new treatments for life-threatening and rare diseases. The first generation of bio pharmaceutical products produced using recombinant technologies was launched in the 1980s and is now on the way to patent expiration. As a result, research and generic pharmaceutical companies are seizing the opportunity to develop “generic” substitutes for original biologics, referred to here as biosimilars. However, the process of introducing an innovator's biosimilar product is much more complex than the relatively straightforward process of introducing a generic equivalent of an innovator's product based on a new chemical entity. Biologics are produced by cells in culture or whole organisms, which are inherently more variable than chemical synthesis methods. Therefore, unlike generic drugs, it is not possible to create an identical or identical copy of the innovator product. In this way, biosimilars are "similar but not the same" or in other words biosimilars are "a twin but not a clone" of the original biologic innovator product. The field of biosimilars therefore presents several important challenges, including i) validation of similarity, ii) interchangeability of biosimilar and innovative products, iii) possible need for a unique nomenclature to distinguish different bio pharmaceutical products, iv) regulatory framework, v) business opportunities as well as guidance for assistance to manufacturers in product development, vi) intellectual property rights and vii) public safety. Keywords: Biosimilars, Biological drugs, Innovative product, Pharmacovigilance.
THE ROLE OF ARTIFICIAL INTELLIGENCE IN PHARMACEUTICAL RESEARCH AND INSTITUTIONAL EDUCATION: CURRENT CHALLENGES AND FUTURE PROSPECTS Panwar, M. S; Verma, Vaibhav; Sankala, Milan
Journal of Global Pharma Technology Volume 17 Issue 03 (2025) March 2025
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Artificial intelligence (AI) has emerged as a transformative tool in pharmaceutical research, enhancing drug discovery, development, and optimization. The integration of machine learning (ML) and deep learning (DL) models has expedited the identification of potential drug candidates, personalized medicine, and predictive analytics for clinical trials. However, despite its rapid advancement, AI in the pharmaceutical industry faces challenges such as data quality, regulatory compliance, and ethical considerations. This paper reviews the commonly used AI models in pharmaceutical research, current obstacles, and the future of AI-driven innovations in the field. Keywords: Artificial intelligence, Machine learning, Deep learning, Drug discovery, Pharmaceutical research, Clinical trials, Personalized medicine.
ROLE OF NANOTECHNOLOGY IN CURRENT ADVANCEMENT VACCINE DEVELOPMENT FOR COVID-19 Mohanty, R
Journal of Global Pharma Technology Volume 16 Issue 01 (2024) January 2024
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The most recent human coronavirus known as COVID-19(SARS-CoV-2) has already spread around the world. This review describes the accumulated knowledge of the previous SARS-CoV, MERS-CoV infections and aim to help understand the newly emerged SARS-CoV-2 infection. Advances in nanotechnology over the past decades to develop new nanomaterials and step forward in the application of new technology tools. Finally nanotechnology approach describes vaccine development and therapeutics drugs developed nanomedicines which are currently undergoing clinical trial to become innovative alternatives for overcoming COVID-19 vaccine. Nanoparticles are non-toxic antiviral showed great promise to provide nano vaccine against viral infection. Keywords: Nanotechnology, Vaccine Development, COVID-19.
EXPLORATION OF ANTI-EPILEPTIC PROPERTY OF METHANOLIC EXTRACTION OF OCIMUM BASILICUM Ray, J; Rout, M; Prusty, S; Mohanty, R; Sahu, P
Journal of Global Pharma Technology Volume 16 Issue 02 (2024) February 2024
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The goal of the current investigation was to determine if a methanolic extract of Ocimum Basilicum (O.B.) leaves could protect against phenytoin induced Epilepsy. Epilepsy was studied using dosages of 400mg/kg is more effective than 200 mg/kg of methanolic extract of O.B. The extract was administered, which improved improve behavioral disturbances, oxidative stress can be reduced and antioxidant enzymes can be recovered. The results of this investigation showed that rats treated with a methanol extract of O.B. leaves have neuroprotective potential. Therefore, it can be inferred that Ocimum basilicum may be useful in the treatment of Epilepsy disease. Keywords: Ocimum Basilicum (O.B), Leaves, Phenytoin, Rat.
CHROMATOGRAPHIC EVALUATION OF DIFFERENT EXTRACTS OF VENTILAGO MADERASPATANA GRAETN. Ahire, Sujeetkumar I.; Ahire, Sandhya S.; Jain, Akshata A.
Journal of Global Pharma Technology Volume 16 Issue 02 (2024) February 2024
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Chromatographic studies were carried out on leaves and stem extracts of Ventilago maderspatana Gaertn belonging to the family Rhamnaceae. It is an important and well known plant in the Indian system of medicine. Leaf and stem samples of V. maderspatana were subjected to maceration by using distilled water and ethanol. Aqueous and ethanolic extract were prepared from the leaf, stem of Ventilago maderspatana. Preliminary phytochemical analysis was carried out for all extracts. All extract were found to contain different phytoconstituents such as alkaloids, glycosides, steriods and sterols, saponins, flavonoids, carbohydrates, and tri- terpenoids and showed the absence of amino acids, proteins and acidic compounds. Extract were subjected to TLC and HPTLC analysis. Keywords: V. maderspatana, Leaf and Stem extract, Chromatographic evaluation.
EXPLORING POST-COMPRESSION PARAMETERS IN MARKETED VILDAGLIPTIN TABLETS Siva, P Krishna
Journal of Global Pharma Technology Volume 16 Issue 03 (2024) March 2024
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This study investigates the post-compression parameters of tablets produced by five prominent pharmaceutical brands. Tablets play a crucial role in drug delivery, and their quality is essential for ensuring therapeutic efficacy. The post-compression phase is a critical step in tablet manufacturing, influencing key parameters such as weight variation, hardness, friability, and disintegration. This research aims to assess and compare these parameters for tablets from five selected brands, confirming their adherence to quality standards. The tablets from Brand A, Brand B, Brand C, Brand D, and Brand E underwent a rigorous testing protocol to evaluate hardness using a calibrated hardness tester, friability through Roche friabilator, and disintegration employing a disintegration tester. The study utilized standardized testing methods to ensure consistency and reliability across all assessments. Results revealed that all five brands successfully met benchmarks for weight variation, hardness, friability, and disintegration time. The tablets demonstrated robust mechanical strength, minimal friability, and prompt disintegration of active pharmaceutical ingredients. Keywords: Post-compression, Hardness, Friability, Disintegration.
REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION-A REVIEW Sri, K. Bhavya; Banu, Shaheen; Sumakanth, Mogili
Journal of Global Pharma Technology Volume 16 Issue 03 (2024) March 2024
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The reverse transcription polymerase chain response is straightforward, powerful, and exquisite innovation in the discipline of molecular biology. It helps in determining the gene expression and amplifying the gene of interest in numerous fields used to locate and quantify the quantity of a given DNA collection. It entails three steps: reverse transcription, PCR amplification, and electrophoresis. Among PCR, the maximum commonly used PCR technique is reverse transcription polymerase chain reaction abbreviated as RT-PCR. it is way utilized in molecular biology & genetic research that allows the detection & quantification of mRNA. in this, RNA template is first converted into a complementary DNA by use of a reverse transcriptase enzyme and is further used for exponential amplification the use of the PCR method. Many genes are recognized to have their own promoter regions that inform cells where to begin transcribing the unique gene. RT-PCR first starts by using the usage of reverse transcriptase enzyme to make DNA out of RNA that has been extracted from cells or tissue samples. The RNA is in the shape of a polymer. The opposite transcriptase copies the RNA into an open-ended DNA strand, preventing it when it encounters a unique non-coding location known as a "poly-A tail" for each 20 to 23 nucleotides. The PCR method then begins by blending the newly made DNA with known primers to expand or reflect a selected piece of DNA. The pattern is then heated and cooled more than one instance, which causes the DNA to split into exclusive string sizes, brief and long. the quick string represents the newly copied RNA that can be visible as amplification, while the longer strand represents each the amplified RNA and all other non-amplified DNA portions collectively. The difference in the duration of DNA strands is what offers reverse transcriptase PCR its name. RT-PCR approach is performed in a thermocycler for the huge production of genetic fabric. It includes several wells, thermos regulators, a detector, and a gadget hooked up with appropriate software. Keywords: Amplification, Thermocycler, Gene expression, cDNA, Molecular biology, RT-PCR, Template.

Page 242 of 244 | Total Record : 2438

 240   241   242   243   244 

Filter by Year

2010 2025


Reset
Filter By Issues
All Issue Volume 17 Issue 12 (2025) Dec. 2025 Volume 17 Issue 11 (2025) Nov.2025 Volume 17 Issue 10 (2025) Oct. 2025 Volume 17 Issue 04 (2025) April 2025 Volume 17 Issue 03 (2025) March 2025 Volume 17 Issue 02 (2025) Feb. 2025 Volume 17 Issue 01 (2025) Jan 2025 Volume 16 Issue 12 (2024) Dec. 2024 Volume 16 Issue 11 (2024) November 2024 Volume 16 Issue 10 (2024) October 2024 Volume 16 Issue 09 (2024) September 2024 Volume 16 Issue 08 (2024) August 2024 Volume 16 Issue 07 (2024) July 2024 Volume 16 Issue 06 (2024) June 2024 Volume 16 Issue 05 (2024) May 2024 Volume 16 Issue 04 (2024) April 2024 Volume 16 Issue 03 (2024) March 2024 Volume 16 Issue 02 (2024) February 2024 Volume 16 Issue 01 (2024) January 2024 Volume 14 Issue 05 (2022) May 2022 Volume 13 Issue 05 (2021) May 2021 Volume 13 Issue 04 (2021) April 2021 Volume 13 Issue 03 (2021) March 2021 Volume 13 Issue 02 (2021) Feb. 2021 Volume 13 Issue 01 (2021) Jan. 2021 Volume 12 Issue 12 (2020) Dec. 2020 Volume 12 Issue 11 (2020) Nov. 2020 Volume 12 Issue 10 (2020) Oct. 2020 Volume 12 Issue 09 (2020) Sept. 2020 Volume 12 Issue 08 (2020) Aug. 2020 Volume 12 Issue 07 (2020) July 2020 Volume 12 Issue 06 (2020) June 2020 Volume 12 Issue 05 (2020) May 2020 Volume 12 Issue 04 (2020) April 2020 Volume 12 Issue 03 (2020) March 2020 Volume 12 Issue 02 (2020) Feb. 2020 Volume 12 Issue 01 (2020) Jan. 2020 Volume 12 Issue 08 Volume 11 Issue 12 (2019) December 2019 Volume 11 Issue 11 (2019) November 2019 Volume 11 Issue 10 (2019) October 2019 Volume 11 Issue 09: (2019) September 2019 Volume 11 Issue 09 (2019) September 2019 Volume 11 Issue 08 (2019) Aug. 2019 Volume 11 Issue 07 (2019) July 2019 Volume 11 Issue 06 (2019) June 2019 Volume 11 Issue 05 (2019) May 2019 Volume 11 Issue 04 (2019) April 2019 Volume 11 Issue 03 (2019) March. 2019 Volume 11 Issue 02 (2019) Feb. 2019 Volume 11 Issue 01 (2019) Jan. 2019 Volume 11 Issue 2: 2019 Volume 10 Issue 12. Volume 11 Issue 6. Volume 10 Issue 12 (2018) December 2018 Volume 10 Issue 11 (2018) November 2018 Volume 10 Issue 10 (2018) October 2018 Volume 10 Issue 09: (2018) September 2018 Volume 10 Issue 08: (2018) August 2018 Volume 10 Issue 07: (2018) July 2018 Volume 10 Issue 06: (2018) June 2018 Volume 10 Issue 05: (2018) May2018 Volume 10 Issue 04: (2018) April 2018 Volume 10 Issue 02: (2018) Feb 2018 Volume 10 Issue 01: (2018) Jan. 2018 Volume 10 Issue 10: 2018 Volume 10 Issue 01 Volume 09 Issue 12 Volume 09 Issue 11 Volume 9 Issue 11 . Vol. 9 Issue 7 : 2017 Volume 9 Issue 10 Volume 09 Issue 09 Volume 09 Issue 08 Volume 9 Issue 07 Volume 09 Issue 05 Volume 09 Issue 04 Volume 09 Issue 03 Volume 09 Issue 02 Volume 08 Issue 11 Volume 08 Issue 07 Volume 08 Issue 06 Volume 08 Issue 05 Volume 08 Issue 04 Volume 08 Issue 03 Volume 08 Issue 02 Volume 08 Issue 01 Volume. 9 Issue 6 Volume 08 Issue 10: (2016) October 2016 Volume 08 Issue 09: (2016) September 2016 Volume 12 Issue 01 Volume 11 Issue 07 Volume 11 Issue 05. Volume 11 Issue 04. Volume 11 Issue 03 Volume 11 Issue 01. Volume 08 Issue 08 Volume 04 Issue 02: (2012) February 2012 Volume 03 Issue 06: (2011) June 2011 Volume 03 Issue 04: (2011) April 2011 Volume 02 Issue 10: (2010) Oct.2010 Volume 02 Issue 07: (2010) July 2010 Volume 02 Issue 05: (2010) May 2010 Volume 02 Issue 03: (2010) March 2010 More Issue