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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
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A Morphological Study and a New Species Registration of Genus Xerophloea Germa, 1839 Sp.nov. From sub-family Ledrinae Fairmai, 1855 of the Leafhopper (Hemiptera: Cicadellidae) in Iraq Rawa' J. H. Al-Kaissy
Journal of Global Pharma Technology Volume 11 Issue 07
Publisher : Journal of Global Pharma Technology

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Abstract

The external morphology was studied and registered for a new species of genus Xerophloea Germa, 1839 where the samples were collected during the seventh month in 2018 of the Adhamiyah region in Baghdad city, Iraq and 3♀ using the light trap. The samples were diagnosed using taxonomic keys and the parts of insect were described and photographed successively, the adult insect, vertex, head, pronotum, mesonotum, abdomen, the front wing, as well as female genitalia, using Lucida’s camera.Keywords: Hemiptera, Cicadellidae, Ledrinae.
Improvement the Photo Catalytic Properties of ZnS nanoparticle with Loaded Manganese and Chromium by Co-Precipitation Method Luma Majeed Ahmed
Journal of Global Pharma Technology Volume 10 Issue 07: (2018) July 2018
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Abstract

This work aims to study the photocatalytic decolorization of Reactive black 5 as the commercial azo reactive dye was studied  with  a presence prepared  ZnS nanopowder and metalized by manganese and chromium (1:1)%. These prepared catalysts were have been made by using a co-precipitation method. The characteristics of prepared samples were investigated by X-ray  diffraction(XRD), AFM and fluorescence spectrometry, XRD data were  helpful to calculate the mean crystal size by the using Scherrer equation , the mean crystal  size for prepared bare ZnS is more  value compared with that value for prepared Mn: ZnS: Cr  and equal to19.986 and 17.114 respectively.  The AFM images explained that the shapes for prepared samples are semispherical and the number of particle sizes of them that equal to 93.740, 51.020 for bare ZnS and metalized (Mn, Cr) ZnS respectively. The Crystallinty index was calculated by depending on particle sizes attained from AFM and mean crystallite sizes obtained from XRD and results indicated to the particle sizes for them contain (5-3) crystals. The results of measured Bg of prepared samples were obtained, that the Bg of prepared ZnS was a small value (3.558 eV) at λ max =348.5while the Bg of metalized ZnS was (3.568 eV) at λ max =347.5. Atomic absorption spectrometry was used to ensure if all the loaded amounts from Mn: Cr were completed that, so, the loaded process is successful. The effect of temperature was estimated the calculated activation energies for prepared ZnS and prepared Mn: ZnS: Cr ( 14 ∆Ea=20.760 kJmole"> & 14∆Ea=13.420 kJmole)">  respectively. The  Efficiency (E %) of decolourization for reactive black 5 dye with prepared samples under the UV- A light whose intensity is equal to   (1.46 x 1410-7"> ) Einstein. s-1  was calculated for all prepared sample and indicated tothe effect of the metal loaded to increase the  efficiency % for metalized ZnS 87.128% compared with prepared ZnS E% 73.394%.Keyword: Textile wastewater, Advanced oxidation processes, Reactive Black 5 dye.
Effect of Using the Innovative Light Zone to Develop the Accuracy of Performance the Forehand and Backhand Skills for Female in Tennis Mohammed Naji Shaker Abugneam
Journal of Global Pharma Technology .
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Abstract

The researchers designed an electric-powered appliance with different light-colored signs. These signs are shown on a wooden base. Exercises were used to develop motor precision and to perform forehand and backhand in tennis. The playing area was divided into several zones, and according to the direction of each skill, the tag was used. Thus, students were able to perform two skills accurately. The game of tennis requires visual kinetic compatibility between the eye, arm, eye and foot compatibility, a visual marker designed to make students more focused and accurate on performance in difficult areas of skills. The exercises were carried out by the experimental group for 12 weeks with two training units with 24 training modules. Arteries in the variables of the statistical results showed experimental superiority over control.Keywords: Tennis exercises, Light zone appliance, Motor accuracy, Forehand and backhand in tennis.
Determination of the Fungicidal Properties of Plants and Herbal Combinations against Ascosphaera Apis l. Fitrat Yumaguzhin
Journal of Global Pharma Technology Volume 12 Issue 01
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Abstract

The urgency of the problem under investigation is due to the need to develop plant means for the prevention and treatment of fungal diseases in bee colonies. The aim of the article is: * to search for medicinal plants with fungistatic activity in relation to the causative agent of chalkbrood; * to create herbal combinations and to comparatively evaluate their activity in laboratory and production conditions with the chemical compounds recommended for chalkbrood treatment. The main laboratory method for assessing the fungistatic activity of plants and herbal combinations is comparing the zones of delayed growth of the chalkbrood causative agent in experimental and control media. In the production environment, the influence of herbal combinations was assessed by comparing the quality of wintering of bee colonies, the rate of their spring development, the reduction of bee larvae infected with chalkbrood and the amount of collected honey. Laboratory conditions revealed that alcohol extracts of celandine (Chelidonium majus), fir needles (Abietis sibiricae) and pot marigold, or calendula (Calendula officinalis), had a pronounced fungistatic effect (comparable to that of the chemical compounds) on the growth of the mycelium of Ascosphaera apis. Several herbal combinations were prepared which, in vitro, also had a pronounced fungistatic effect. Under their influence, the preservation of bee colonies during wintering was improved, the incidence decreased, and honey production increased. The materials of the article can be of use for scientists working on developing drugs for the prevention and treatment of fungal diseases in bee colonies, as well as for beekeepers who do not use chemical compounds in their produce.Keywords: Medicinal plants, Wintering of bee colonies, Catalase, Spring development, Chalkbrood.
The Effect of Special Exercises in the Diamond Style in Some Physiological Variables and the Basic Skills of Futsal Players Abbas Mahdi Saleh
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

As the importance of research in the preparation of special exercises and knowledge of their impact in some physiological variables and basic skills of futsal players. The problem of research: researchers see the problem of research is slow to move the player of the station from the attack to defend when the loss of the ball and this generates pressure by the opposing team because of the numerical increase of the players of the opposing team, especially in the case of possession of the ball begins to weaken in this style of midfield Will cause serious problems in defending the goal of the team and will work researchers put physical exercises and skills to develop the basic skills, variables and physiology to promote the reality and development of this method.Research ObjectivesPreparation of exercises in the style of diamond for futsal players.To identify the effect of the exercises in the diamond style in some physiological variables and the basic skills of futsal players.Research HypothesisThere is an impact of the exercises in the diamond style in some physiological variables and the basic skills of futsal players.As for the research methodology and its field procedures, researchers used the experimental method to solve the problem of research. The research society was determined by the players of the University of Kufa for the halls of futsal, and they were divided into two groups (experimental and control) in the simple random way (Lottery).As for the most important conclusions and recommendations, the most important conclusions are the following:The exercise of the diamond method helped to develop some physiological variables (the concentration of lactic acid, the enzyme L.D.H) in the members of the experimental group.Diamond-style exercises have helped to develop the basic skills of members of the futsal group of the gyms.The main recommendations included the following:Recommend the researchers to pay attention to the use of special exercises in accordance with the diamond style when training the futsal players.Researchers recommend conducting similar studies on different age groups.Keywords: Special exercises, Diamond style, Physiological variables and basic skills.
Anti-obesity effect of Dunaliella salina: Study on the gastric inhibitory polypeptide, ROS, DNA damage and metabolic gene expression in rats Howaida Ibrahim Abd-Alla
Journal of Global Pharma Technology Volume 11 Issue 04.
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Abstract

This study aimed to identify the gene expression profiling of lipid related genes in animal model of obesity and the role of microalgal Dunaliella salina (alga) in modulating the expression of these genes during the initial period of obesity. The diet-induced obesity model was used using fifty male Wistar albino rats (weighing 150-160 g) that have obesity caused by being fed high-fat diet (HFD) for 12 weeks. These rats were randomly divided into 2 groups (10 rats each) and treated with D. salina extract and orlistat for 6 weeks. The anti-obesity effect of this halophilic unicellular green alga was compared to orlistat, a standard anti-obesity drug promoting weight loss as a gastric and  pancreatic lipase inhibitor. Treatment with the alga and orlistat showed significant effect in reducing gastric inhibitory polypeptide (GIP). Also, the treatment of obesity-induced rats with the alga increased significantly the mRNA expression levels of lipid catabolic genes (peroxisome proliferator-activated receptor PPAR-α and carnitine palmitoyltransferase CPT-1) and decreased significantly the expression levels of lipid anabolic gene (SCD-1) compared with obesity-induced rats. In addition, D. salina extract was able to decrease ROS generation and inhibit the rate of DNA damage in obese rats. The study was extended to evaluate the phytochemical composition of  microalgal extract. The fatty acid methyl esters were analyzed by GLC. The extract contained considerable level of omega-3 fatty acids. The presence of  palmitic (62.5%), linolenic (9%), oleic (8.6%) and linoleic (7.4%) was revealed. The percentage of saturated and unsaturated fatty acids were 67.7 and 32.1%, respectively. D. salina extract administration which is rich in omega-3 fatty acids, has anti-obesity properties. Results suggested that D. salina might be available as functional alga and bioactive diet supplement for the treatment of obesity.
Purify and Characterize the Xylanase from the Local Isolation of Trichoderma Longibrachiatum Shimal Younis Abdel-Hadi
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
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Abstract

Fungi are well known for their ability to produce extracellular enzymes into their surrounding environment. Xylanases are an important class of hydrolytic enzymes involved in degradation of xylene a backbone of hemicellulose, in this study; we have isolated three isolates of xylene analytic fungi taken from five samples of sand gathered from different sites in the University of Mosul. Depending on the halo's diameter of analysis and by using the Congo red indicator, one isolate has got a high activity in producing the exocellular xylanase enzyme related to Trichoderma longibrachiatum on the base of morphological, microscopic and internal area (ITS) features. The xylanase has been purified from the raw extracted enzyme of the selected isolate throughout four subsequent steps included: sedimentation by Ammonium Sulphate, dialysis, gel filtration in column (Sephadex-G 100) and the Ionic exchanger (DEAE Cellulose). After this step, the number of filtrations is (49.22) with enzymatic outcome reaching to (33.93%). Studying the description of the filtered enzyme, PH the optimal for the enzyme activity is 0.5 and the optimal range of PH for enzyme stability is (4-6). Moreover, the optimal temperature degree for enzyme activity is (50 °C), whereas the optimal temperature degree for enzyme stability is (50-60 °C).Keywords:  Mosul university, Xylanase, Trichoderma longibrachiatum.
Azotation and Coupling Reaction of Amino Oxadiazole Ligands with (Characterization, Chromatography, Solubility) Study Muhammed Abdel Hasan Shallal
Journal of Global Pharma Technology Volume 10 Issue 01: (2018) Jan. 2018
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Abstract

This  paper  involved   reaction  between   two moles of   semicarbazide   with  mole  of  diethyl malonate which   refluxed   for ( 17 hrs ) in absolute  ethanol   then  added ( 4 ml ) of  H2SO4 to produce amino  oxadiazole  , the  resulting  compound   used     in  azotation  then  coupling   reaction with  various   coupling  derivatives   of  phenol ( p-hydroxy benzaldehyde , p-hydroxy benzoic acid , p-hydroxy  nitrobenzene , p- hydroxyl toluene , p- hydroxyl phenol )to produce novel  oxadiazole   derivatives   as  a ligands .The above  ligands  were investigated    through   their spectral  methods  (UV- Vis , FTIR  ,1HNMR  , Mass ) , Chromatography  technique   and  studying  of  solubility  in  series   solvents.Keywords: Soluble, Series, Hydroxyl.
Exploring of Insertion/deletion Polymorphism in the Vascular Endothelial Growth Factor Gene Associated with Type 2 Diabetic Patients in Al-Diwaniyah City Mohanad Jawad Kadhim
Journal of Global Pharma Technology .
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Abstract

Disease conditions that are related to the effects of the vascular endothelial growth factor (VEGF) are common such as nephropathy and promoting of cancer growth and metastasis. The current study was launched to explore the presence of VEGF gene-based polymorphism of the insertion/deletion (I/D) in blood samples of 25 diabetic and 25 clinically healthy people in Al-Diwaniyah City, Iraq. Using polymerase chain reaction (PCR), the results have shown the presence of these genotypes in these samples with higher significant (p˂0.05) occurrence. The homozygous DD was significantly (p˂0.05) affected by the sex factor. This genotypic characteristic was shown significantly (p˂0.05) in females more than that in males. Moreover, this feature was significantly higher (p˂0.05) when compared to the other genotypes II and I/D for each of the females or males separately. For the DD genotype, ages between 40 to 49 years of old have shown significantly (p˂0.05) higher presence of this genotype than that in other ages. It has been also shown by these results that this genotype is present significantly (p˂0.05) higher than that in the other genotypes when compared together in each age category. These results suggest current relationship between the VEGF I/D polymorphism occurrence and diabetes with deeper correlation with sex and age factors.Keywords: VEGF I/D polymorphism, diabetes, sex, age.    
The Use of Diuretics on Hepatic Cirrhosis Patient with Ascites Didik Hasmono
Journal of Global Pharma Technology Volume 11 Issue 6.
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Abstract

Background: Hepatic cirrhosis with ascites complication increases the mortality up to 50% in a matter of years. Diuretics are a class of drugs that are often used as choices. The pattern of diuretics use of hepatic cirrhosis patient with ascites in the hospital needs to be studied further because if the use is not appropriate, it will potentially lead to drug related problems that affect patient management. Aim: to examine the pattern of diuretics use of hepatic cirrhosis patient with ascites which undergoing treatment in the hospital inpatient unit. Method: a descriptive and retrospective study using medical records. Criteria for inclusion of the sample were (1) Hepatic cirrhosis patient with ascites complication (2) Age> 20 years (3) Receive diuretic therapy (4) Complete medical record. The exclusion criteria were patient who was hospitalized for less than 3 days. Study samples were recorded on the data collection sheet. Sampling with time limited sampling method. Result: The total number of patients who met the inclusion criteria was 45 patients. The diuretics which most used was furosemide, both in single doses and in combination with Spironolactone. The hepatic cirrhosis patient with ascites in this study not only received diuretic therapy, but patient also received other drugs that used to prevent and overcome complication. In drug interaction, the potential use of Spironolactone with Potassium (KCl or KSR) preparation increases the risk of hyperkalemia. Conclusion: Most of the diuretic therapies obtained by hepatic cirrhosis patient with those who were hospitalized which have been in accordance with the available guidelines.Keywords: As cites, Drug Related Problems, Diuretics, Hepatic Cirrhosis.

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