cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
I Wayan Sudarsa
Contact Email
sudarsa@unud.ac.id
Phone
-
Journal Mail Official
globalpharmatechnology@gmail.com
Editorial Address
India
Location
Kota denpasar,
Bali
INDONESIA
Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
 76   77   78   79   80 
Antibacterial Activity of Origanumvulgare Leaves against Different Types of Bacteria Isolated from Urinary Tract Infection Patients in Baghdad/Iraq Hayfaa M. Fahad
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (511.261 KB)

Abstract

In the gift study, antibacterial drug potency of Origanumvulgare was studied on four sorts of morbific microorganism isolated from urinary tract infection patient samples, Staphylcoccus aureus, E. coli, Klebsiella pneumonia, and Sallmonellatyphi by agar well diffusion assay. The repressive effects of this leaves extract were compared with control distilled water. The inhibition result of Origanumvulgare in numerous concentration against microorganism growth were studied, the results showed that there's an excellent inhibition growth on all studied microorganism isolates except Klebsiella pneumonia. This study conclude that the data ensure the antibacterial drug potential and highlight the promising role of oregano as new lead structure within the explore for novel antibacterial drug agents. Therefore, any experiment involving a bigger sample size and extract a concentration is deserve analysis.Keywords: antibacterial drug, Vulgare.
Assessment of Lipid Profile and Cytokine (IL-13, TGF-β) with sICAM-1in Patients Infected with Intestinal Parasite (Entamoeba histolytica, Giardia lamblia and Blastocystis hominis) Esra I. Wahid-Aldeen
Journal of Global Pharma Technology Volume 11 Issue 03
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (635.278 KB)

Abstract

Tests were assessed in sera of 150 patients infected with intestinal parasites of E.histolytica (50 case), Giardia lamblia (50 case) and Blastocystis hominis (50 case), as well as 20 apparently healthy controls whom attended to Children Hospital , Kirkuk General Hospital And Azadi teaching Hospital in Kirkuk city-Iraq, from February- August 2017. Biochemical parameters include a lipid profile, while immunological parameters include serum level of IL-13, TGF-β and soluble intracellular adhesion molecule-1) sICAM-1 (. Biochemical parameters showed a significant correlation between low serum lipid levels in infected intestinal parasites especially in the level of cholesterol was significantly decreased in patients infected with G.lamblia (107.36 ± 10.82 mg/dl) and E.histolytica(110.88 ± 9.45 mg/dl) compared to control group and patients infected with B.hominis (P ≤ 0.05) . The level of T.G. and VLDL also showed significantly decreased in patients infected with E.histolytica(57.52 ±8.73 mg/dl) compared to control and patients infected with B.hominis, while all patients showed a significant decrease in HDL level. Serum level of IL-13 and sICAM-1were significantly increased in all patients infected with intestinal parasite, while there was a significantly increased serum level of TGF-β in patients infected with B.hominis and E.histolytica, the current study conclude that intestinal parasite work to consumed fat from the host because it cannot synthesize it by itself , and this result suggest ­­a role of IL-13 pathogenesis of intestinal parasitic infection ,also the  increase in the level of TGF-β and sICAM-1 in B.hominis patient may suggest that TGF-β causes increased expression of endothelial ICAM-1and neutrophil-mediated intestinal injury.Keywords: Entamobea histolytica, Giardia lamblia, Blastocystis hominis, sICAM-1, IL-13, TGF-β, Lipid Profile.
Effect of Adding Zirconia and Alumina Nanoparticles on the Tensile and Flexural Properties of Polymer Blend Based on Polypropylene Teeb Adnan Mohameed
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (921.627 KB)

Abstract

Polypropylene is an important material used in many structural applications, including automotive and aircraft parts as well as machine parts.  In this paper, the properties of polypropylene were improved by blending it with 5% ratio of poly methyl methacrylate (PMMA) and adding nanoparticles powders of zirconia (ZrO2) and alumina (Al2O3) in different ratios (0.3, 0.5 and 0.7%) to polymer blend, which consists of [PP: 5% PMMA and adding 1% of (polypropylene-grafted-malic anhydrated (PP-g-MA) as compatibilizing agent)]. Polymer blend and its nanocomposites were prepared by melt blending technique using twin screw extruder. Investigation of some mechanical properties and the morphology structure test of the nanocomposites samples was studied. The results illustrated that the mechanical properties increased when adding nanoparticle (ZrO2 and Al2O3) to polymer blend (PP: 5%PMMA: 1%(PP-g-MA)) and the highest values were obtained for tensile strength, modulus of elasticity, flexural strength and flexural modulus, at 0.3% ratio of (ZrO2 and Al2O3) nanoparticles in the blend. The fracture surface morphology showed that the addition of nanoparticles led to reduce the micro pores that exist in the morphology structure of polymer blend.Keywords: Polymer blend, Nanocomposite, PP, PMMA.
Assessment of Heavy Metals in Some Ground Water Wells at Baghdad City /Iraq Husam Saleem Khalaf
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Occurrence the heavy metals in water is one of the most important concerns. may cause savior health problems. In this work we made an attempt to know the quantity of six heavy metals in groundwater in different locations of Baghdad city. Examinations were made on groundwater of the review region to assess the heavy metals. Groundwater samples were gathered and analyzed utilizing Atomic Absorption Spectrophotometer for their Manganese, Iron, Zinc, Cadmium, Copper and Lead content and their levels compared with World Health Organization (WHO) specified maximum contaminant level. In order to accomplish this, water samples were obtained from 10 randomly selected wells in the region, in February and August, 2016. The study showed that the groundwater in the study area were generally alkaline (moderate) and contained Cu+2, Fe+2, Pb+2, Cd+2, Cu+2 and lead concentrations that are higher than the permissible limits suggested by the (WHO). The study can then be concluded to be contaminated with some heavy metals because of the effect of many activities in the survey area. Decreased the operation of Industrial treatment, laws and the integrated management led to deteriorating the groundwater quality. Also the study inclusion the TDS and EC in the groundwater in these locations.Keywords: Determination, Heavy metal, Atomic absorption, Groundwater wells.
STUDY OF THE SYSTEM OF CYTOKINES IN CASE OF HERPETIC AND CHLAMYDIA-HERPETIC INFECTION E.V. Markelova
Journal of Global Pharma Technology Volume 08 Issue 09: (2016) September 2016
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The levels of TNF-α, TFN-β, IFNγ and IL-10 in the venous blood serum and the ejaculate from 80 men with sexually transmitted infections – the main group (MG) were studied. All men of OG were divided into 2 groups: 40 men with chronic viral urethritis (genital herpes – herpetic urethritis (HU)) and 40 men with viral-bacterial urethritis (genital herpes in conjunction with clamidiosis – herpetic-chlamydial urethritis (HCU)). The comparison group (control group) consisted of 20 apparently healthy male volunteers. More pronounced disorders of local and systemic immunity in the group of men with urethritis of viral and bacterial origin were found in both in venous blood serum and in the ejaculate. Keywords: cytokines, ejaculate, herpes, clamidiosis.
Synthesis, Spectral Characterization and Studies of New Heterocyclic Azo Dye Compound Derived From Imidazole with Some Transition Metal Complexes Zainab. J. Mohammed
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

A new heterocyclic azo ligand (E)-2-((4,5-bis(4-methoxyphenyl)-1H-imidazol-2-yl)diazenyl) benzoic acid, (CPMI=HL) was prepared by coupling diazotized of anthranilic acid with 4,5-bis(4-methoxyphenyl)-1H-imidazole in alkaline ethanolic solution. Eight complexes with Mn(II) , Fe(II), Co(II) ,Ni(II) ,Cu(II) ,Zn(II) ,Cd(II) and Hg(II) ions. These complexes and ligand were characterized by elemental analyses, IR, U.V-Vis spectra, mass spectra, (ligand and its Copper (II) complex), magnetic moments, Atomic absorption and molar conductance measurements. The IR data show that, the azo molecule behaves as a mono negative tridentate(N, N,O) ligand and linked through the carboxlicoxygen atom, azomethanic nitrogen of heterocyclic imidazole molecule and nitrogen atom of azo group, produces colored chelates with transition metal ions.The molar conductance data for all complexes are nonelectrolyte. Based on analytical and spectral data we proposed a monomeric octahedral geometry for all chelate complexes and d2sp3 or sp3d2 hybridization.Keywords: Azo imidazole, Chelate complexes, Characterization. 
Cyperus Rotundus L. Phenols Extracts Enhance the Anticancer Effect of Oncolytic Newcastle Disease Virus on Digestive System Neoplasms Ahmed Majeed Al-Shammari
Journal of Global Pharma Technology Volume 11 Issue 07
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (754.267 KB)

Abstract

This study created novel cancer therapy consist of a combination of Secondary metabolites compound (Phenols) extracted from Cyperus rotundus L. and oncolytic Newcastle disease virus (NDV) which showed cytotoxic activity against different cancer cell lines in vitro. Moreover, it is safe and less toxic on normal cell lines. Three cancer cell lines were used, esophagus cancer cell line (SKG), mouse hepatocellular carcinoma cell line (HC), Human rectal cancer cell line (HRT), and normal cell line Rat Embryo Fibroblast (REF). MTT cell viability assay was used and analyzed for possible synergism using the Chou-Talalay analysis method. In vitro study showed that combination therapy of NDV with Phenols extract had enhanced synergistic anticancer activity on all cancer cell lines tested. Moreover, combination therapies showed antagonism and less cytotoxic effect on normal REF cell line.Keywords: Cancer cell line, Combination therapy, Newcastle virus, phenols, Cyperus rotundus.
Quality of Life of Hypertensive Patients with Candesartan and Candesartan-Amlodipine Combination Therapy at a Governmental Hospital in Yogyakarta, Indonesia Faridah Baroroh
Journal of Global Pharma Technology Volume 12 Issue 09 (2020) Sept. 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (486.898 KB)

Abstract

Many types of antihypertensive drugs produce different efficacies, and their use in therapy is often associated with unpleasant side effects that diminish the quality of life. This prospective cohort study intended to compare the impacts of two different treatments, namely candesartan and the combination of candesartan and amlodipine, on the quality of life of hypertensive outpatients at a government hospital in Yogyakarta, Indonesia. Starting with preliminary data survey, the analysis continued to measuring the quality of life of 100 respondents, which had met the inclusion and exclusion criteria, after three months of therapy. In the EQ5D questionnaire on quality of life, the EQ5D dimension was converted to EQ5D Index. The data analysis involved chi-square and correlation tests. The EQ-5D index ranged from 0.540 to 0.933 with an average of 0.819. Based on gender and complications, the quality of life of the patients who underwent candesartan therapy was not significantly different from those who took candesartan and amlodipine (p> 0.05). Meanwhile, based on age, occupation, income, and education, a significant difference was detected (p <0.05). The quality of life significantly correlated with age, employment, income, and education (p <0.05) but insignificantly with gender and complications (p> 0.05). As a conclusion, candesartan and candesartan-amlodipine therapies do not affect the quality of life of the patients differently, and the type of treatment is a factor that does not significantly affect the quality of life of the patients (RR; 95% CI = 1.135; 0.812-1.587). Keywords: Quality of life, Candesartan, Candesartan-Amlodipine, Hypertension, Outpatient.
Morphological Component of Uterine Leiomyoma Pathogenesis Andrey Gayday
Journal of Global Pharma Technology Volume 10 Issue 05: (2018) May2018
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

It was shown that the pleonasm of myoma myocytes is one of the main processes that cause an increase in the mass of the tumor. In spite of the fact that momentous cells show similarity with cells of the myometrium, differences in the structure and metabolism of these tissues were unearthed. The paper presents an analysis of the morphological structure of uterine leiomyoma with a view to establishing its pathogenesis. 93 in-treatment patients diagnosed with uterine myoma took part in the research. 60 extirpated uteruses were morphologically investigated. The statistical processing of data included estimation of the arithmetic mean (M), the average error of mean (m) as well as the frequency of the occurrence of features with discrete values. Student’s t-test was used as well as Pearson’s chi-squared test and Fisher’s exact test, the method of multiple intergroup differences, multiple regression analysis and linear discriminant analysis. The modern studies substantially expand our idea of the risk factors and the mechanisms of development of uterine leiomyoma. A comprehensive approach to the study of the myoma provides new data on the prevalence and causes of this disease. One of the main outcomes of the analysis of contemporary data on uterine leiomyoma is the fairly clear interdependence between the character of the growth and the enlargement the tumor as well as the development of multifaceted changes on the systemic and local levels.Keywords: Myoma, Uterus, Reproduction, Histology, Histochemistry, Etiology, Degeneration, Cell Necrobiosis, Denervation.
Synthesis and Characterization of Cadmium-Copper Oxide (CdCu2O4) Nanoparticles by Chemical Co-Precipitation Method in the Presence of Oleic Acid as a Surfactant Abouzar Tahkor
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The present study intended to synthesize cadmium-copper oxide (CdCu2O4) nanoparticles by chemical co-precipitation method in the presence of oleic acidC17H33COOH as a surfactant to control the size of particles. The spherical CdCu2O4nanoparticles were synthesized with an average particle size of 44.79 nm at the calcination temperature of900˚C for 4 hours. The chemical co-precipitation method was utilized as an easy and inexpensive method to produce high-purity mixed oxides. The morphology, network parameters and particle size of the product was studied and characterized by Fourier transform infrared spectroscopy (FT-IR), X-Ray Diffraction (XRD) and Scanning Electron Microscopy (SEM) techniques. The XRD analysis showed the pattern of CdCu2O4corresponded to Perovskite structure and monoclinic symmetry. The average particle size synthesized by XRD almost matched with the particle size observed in SEM image. The results indicated that the amount of surfactant, pH and stirring rate of solution had a crucial role in the homogeneity and particle size of the product.Keywords: Cadmium-copper oxide nanoparticles, Co-precipitation method, nanoparticles, oleic acid, Surfactant.

Page 78 of 244 | Total Record : 2439

 76   77   78   79   80 

Filter by Year

2010 2026


Reset
Filter By Issues
All Issue Volume 18 Issue 01 (2026) Jan. 2026 Volume 17 Issue 12 (2025) Dec. 2025 Volume 17 Issue 11 (2025) Nov.2025 Volume 17 Issue 10 (2025) Oct. 2025 Volume 17 Issue 04 (2025) April 2025 Volume 17 Issue 03 (2025) March 2025 Volume 17 Issue 02 (2025) Feb. 2025 Volume 17 Issue 01 (2025) Jan 2025 Volume 16 Issue 12 (2024) Dec. 2024 Volume 16 Issue 11 (2024) November 2024 Volume 16 Issue 10 (2024) October 2024 Volume 16 Issue 09 (2024) September 2024 Volume 16 Issue 08 (2024) August 2024 Volume 16 Issue 07 (2024) July 2024 Volume 16 Issue 06 (2024) June 2024 Volume 16 Issue 05 (2024) May 2024 Volume 16 Issue 04 (2024) April 2024 Volume 16 Issue 03 (2024) March 2024 Volume 16 Issue 02 (2024) February 2024 Volume 16 Issue 01 (2024) January 2024 Volume 14 Issue 05 (2022) May 2022 Volume 13 Issue 05 (2021) May 2021 Volume 13 Issue 04 (2021) April 2021 Volume 13 Issue 03 (2021) March 2021 Volume 13 Issue 02 (2021) Feb. 2021 Volume 13 Issue 01 (2021) Jan. 2021 Volume 12 Issue 12 (2020) Dec. 2020 Volume 12 Issue 11 (2020) Nov. 2020 Volume 12 Issue 10 (2020) Oct. 2020 Volume 12 Issue 09 (2020) Sept. 2020 Volume 12 Issue 08 (2020) Aug. 2020 Volume 12 Issue 07 (2020) July 2020 Volume 12 Issue 06 (2020) June 2020 Volume 12 Issue 05 (2020) May 2020 Volume 12 Issue 04 (2020) April 2020 Volume 12 Issue 03 (2020) March 2020 Volume 12 Issue 02 (2020) Feb. 2020 Volume 12 Issue 01 (2020) Jan. 2020 Volume 12 Issue 08 Volume 11 Issue 12 (2019) December 2019 Volume 11 Issue 11 (2019) November 2019 Volume 11 Issue 10 (2019) October 2019 Volume 11 Issue 09: (2019) September 2019 Volume 11 Issue 09 (2019) September 2019 Volume 11 Issue 08 (2019) Aug. 2019 Volume 11 Issue 07 (2019) July 2019 Volume 11 Issue 06 (2019) June 2019 Volume 11 Issue 05 (2019) May 2019 Volume 11 Issue 04 (2019) April 2019 Volume 11 Issue 03 (2019) March. 2019 Volume 11 Issue 02 (2019) Feb. 2019 Volume 11 Issue 01 (2019) Jan. 2019 Volume 11 Issue 2: 2019 Volume 10 Issue 12. Volume 11 Issue 6. Volume 10 Issue 12 (2018) December 2018 Volume 10 Issue 11 (2018) November 2018 Volume 10 Issue 10 (2018) October 2018 Volume 10 Issue 09: (2018) September 2018 Volume 10 Issue 08: (2018) August 2018 Volume 10 Issue 07: (2018) July 2018 Volume 10 Issue 06: (2018) June 2018 Volume 10 Issue 05: (2018) May2018 Volume 10 Issue 04: (2018) April 2018 Volume 10 Issue 02: (2018) Feb 2018 Volume 10 Issue 01: (2018) Jan. 2018 Volume 10 Issue 10: 2018 Volume 10 Issue 01 Volume 09 Issue 12 Volume 09 Issue 11 Volume 9 Issue 11 . Vol. 9 Issue 7 : 2017 Volume 9 Issue 10 Volume 09 Issue 09 Volume 09 Issue 08 Volume 9 Issue 07 Volume 09 Issue 05 Volume 09 Issue 04 Volume 09 Issue 03 Volume 09 Issue 02 Volume 08 Issue 11 Volume 08 Issue 07 Volume 08 Issue 06 Volume 08 Issue 05 Volume 08 Issue 04 Volume 08 Issue 03 Volume 08 Issue 02 Volume 08 Issue 01 Volume. 9 Issue 6 Volume 08 Issue 10: (2016) October 2016 Volume 08 Issue 09: (2016) September 2016 Volume 12 Issue 01 Volume 11 Issue 07 Volume 11 Issue 05. Volume 11 Issue 04. Volume 11 Issue 03 Volume 11 Issue 01. Volume 08 Issue 08 Volume 04 Issue 02: (2012) February 2012 Volume 03 Issue 06: (2011) June 2011 Volume 03 Issue 04: (2011) April 2011 Volume 02 Issue 10: (2010) Oct.2010 Volume 02 Issue 07: (2010) July 2010 Volume 02 Issue 05: (2010) May 2010 Volume 02 Issue 03: (2010) March 2010 More Issue