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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
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The Study of Overweight and Obesity Predictors in Children Beginning Elementary School in Rasht City Nasrin Mokhtari
Journal of Global Pharma Technology Volume 08 Issue 07
Publisher : Journal of Global Pharma Technology

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Abstract

چمقدمه : نحوه ارتباط والدین با فرزندان با سبک فرزندپروری آنان ارتباط دارد.سبکهای فرزندپروری نقش مهمی در شکل گیری شخصیت بهنجار و نابهنجار در کودکان داشته و در صورت بکار گیری سبکهای ناکارآمد در تربیت کودکان می تواند منجر به پیامدهای منفی متعددی از جمله مشکلات رفتاری در آنان گردد.Introduction: Overweight and obesity is one of health related problems that its prevalence in developed and developing countries is on rise and has become a public health problem. Objective: This study aimed to determine the predictors of overweight and obesity in children beginning elementary schools in the city of Rasht. Methods: This descriptive cross - sectional study was conducted on 426 children aging 6-7 years old, who were selected by stratified randomized method from two districts of Rasht city from all children who referred to National program of children health measurement. Data collection instrument consisted of a researcher made questionnaire to assess predictors of overweight and obesity and sample’s demographic characteristics. Data were analyzed using t-test and ANOVA and Pearson correlation test.Rیافته ها: نتایج نشان داد که سبک فرزندپروری مقتدرانه هم با نمره کل مشکلات رفتاری درونی سازی (003/RResults: The results showed that 8.6% of boys and 14 percent of children were overweight and 19% of boys and 15.3% of girls were obese. There was a positive relationship between children’s overweight and obesity with family history of obesity (p<0.001), maternal BMI (p<0.02), amount of food eaten in comparison with same age children (p<0.001) and the amount of physical activity for children (p=0.02).Conclusions: Four variables of family history of obesity, maternal body mass index, and parents’ view on food taken compared with other children of the same age and hours of physical activity were shown as predictors of overweight and obesity in children entering elementary school. Keywords: Overweight, Pediatric Obesity, Child.
Information Processing in Accordance with the Rule of Cerebrovascular Mid-Term and Their Relationship to the Level of Performance of Some Scouting Skills for Studies Aqeel Yahya Hashim Abdulaziz
Journal of Global Pharma Technology .
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Abstract

The study of the mental and physiological aspects of the player and learner by the teachers and trainers today has become of great importance. The interest in the study of information processing and treatment levels has emerged as one of the types of learning that has to do with the individual learner himself and to guide him self-directed towards learning by drawing on his knowledge and there is a close connection and according to the type of mental sovereignty or the dominant style of thinking of the athlete whether he has cerebral dominance in the right half or left or there is integrated between the functions of the two halves, and recent years have seen a remarkable interest in the study And the importance of identifying the differences between the two halves of the brain, which contribute to the identification of many things related to human behavior and learning Scouting skills.The researchers followed the following steps in the research procedures:The descriptive approach was used in the method of interconnectivity.The study was conducted on the students of the first stage in the Department of Physical Education College of Education for Girls - University of Kufa for the academic year 2017-2018 The sample (33)The sample was divided according to the test of brain sovereignty to three groups represented the first group (right half), the second group represented (left half), and the third group represented (integrated system).The research requires the use of several tests, including the following:Information processing test.Test the level of information processing systems (right half, left half, integrated system).Skillful skill tests (nodular node, horizontal node).The results of the research:The level of information processing and accuracy of horizontal node performance of the right-hand system is better than those of the left and integrated system.The level of processing information undermining the tent for the right-wing system is better than those of the left and integrated system.Information processing is an important and essential role for people with right, left and integrated systems and the performance of horizontal node and node nodes.Keywords: Information processing, Cerebral dominance, Temporal node and horizontal node.
Role of-Added Sugar in Pediatric-Obesity Ayad Thabt Noaman
Journal of Global Pharma Technology Volume 11 Issue 6.
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Abstract

Added sugars, sweeteners of calories brought to the office or throughout processing and then training on foods, are the most important taxpayer for energy according to aged 2 years but older comes from added sugars. This level is higher than estimated due to 1976-1977 (12.1%), although it is significantly below the estimated 16.9% for 1998 after 2001, it exceeds encouraging guidelines. The biggest contributors to sugars brought in according to American diet are sugar-sweetened beverages, and adolescents are the biggest consumer. Since the devastation about added sugar linked to including weight problems as well as a lot of poor eating or physical repercussions, it is critical that pediatricians, after being aware of this amount, help this association and then after staying familiar with techniques that may Additionally use counseling for at risk patient and their family.
Role of PPAR-Α Signaling Pathway on the Protection of Antituberculosis-Induced Liver Damage by Purple Sweet Potato Extract i gusti ayu artini
Journal of Global Pharma Technology Volume 12 Issue 08
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Abstract

Background: Peroxisome proliferator activated receptor-α (PPAR-α) participates in protecting the liver from many cases of liver damage. It is involved in reducing lipid accumulation, oxidative stress and inflammation. Purple sweet potato extract is one of herbal extract that posses hepatoprotector activity related to its antioxidant and antiinflammatory action. Its hepatoprotective effect on isoniazid and rifampicin induced hepatic injury has not been established yet, as well as its effect on PPAR-α expression and activation in the liver. The aim of this research was to investigate the hepatoprotective effect of purple sweet potato extract on hepatic injury induced by isoniazid and rifampicin, as well as the effect of purple sweet potato on PPAR-α expression and activation in the liver. Methods: The study design was randomized post test only control group design. We included male Wistar rats, age 8-12 weeks, weight 180-220 gram (divided into 3 groups: control, intervention and normal group). The extraction was performed with masseration technique. PPAR-α expression was measured with ELISA; activated PPAR-α was detected using immunohistochemistry; ALT level was measured with spectrophotometry. Data were analyzed using One Way Anova test, continued with Post Hoc test. Results: The result represented that PPAR-α expression in intervention group was significantly higher than control (1.344±0.249 vs. 0.587±0.306; p
Investigation of Anti-Inflammatory Potentials of Terminalia Tomentosa Wight & Arn. Bark - An In-Vitro Approach Richard Lobo
Journal of Global Pharma Technology Volume 09 Issue 08
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Abstract

Terminalia tomentosa bark. Belongs to the family Combretaceae. Bark is astringent and useful in the treatment of ulcers, vata, fractures, hemorrhages, bronchitis and diarrhea.This study establish the anti-inflammatory activity of ethanolic (TEA) and aqueous (TEW) of T. tormentors aback extracts in in-vitro methods by Inhibition protein denaturation (BSA),Inhibition of Egg Albumin denaturationand The human HRBC membrane stabilization method., alcoholic and aqueous extracts exhibited significant protein denaturation inhibition in egg albumin assay with IC50 values TEA113µg/mL, TEW 112.67µg/mL in comparison with Standard (Diclofenac sodium) 236.7µg/ml. In bovine serum albumin denaturation assay with IC50 values TEA 16.91µg/mL and TEW 17.67µg/mL respectively when compared with standard (Diclofenac sodium) 67.21µg/mL. Both alcoholic and aqueous extracts were shown to have membrane stabilization properties with the IC50 values TEA 92.95µg/mL, TEW 37.68µg/mL respectively, in comparison with standard (Diclofenac sodium) 47.48µg/mLTo conclude, this study shows that the T. tormentors, possess significant anti-inflammatory activity.Keywords: Terminalia tomentosa, Anti-inflammatory, Combretaceae, HRBC, Egg albumin Protein denaturation. 
Some of Optical Properties to Titanum Dioxide thin Films at different Calcined Temperatures Khadijh. S. Mohan
Journal of Global Pharma Technology Volume 11 Issue 09: (2019) September 2019
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Abstract

The thin films of titanium dioxide were prepared by sol-gel technique and were deposited by using spin coating method. Some of the optical properties were diagnosed at different annealing temperatures.  Films prepared have been calcined at various temperatures degree for 1 hours or less for each film. The changes of optical properties with the effect of temperatures like optical absorption, optical transmittance and optical reflectivity have been diagnosed and characterized by ultra violet-visible spectrophotometer device. By the way the optical refractive index and optical energy gap were calculated from the relationship mathematical equations that will be mentioned in the results and discussion. It is worth noting that the curves were modified by using polynomial correction. Optical absorptions have been  increased with annealing temperatures, optical reflectivity and  optical refractive index with increasing of annealing temperature at the wavelengths confined between ~ 600nm to ~800nm, while the optical  transmittance showed an opposite results  of the optical  absorbance and  optical energy gaps decreasing with increasing of calcined temperatures.Keywords: Sol-gel, Calcined temperatures and optical transmittance.
The Biological Action of Some Natural Additives Rajaa K. Baqir
Journal of Global Pharma Technology Volume 10 Issue 05: (2018) May2018
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Abstract

Since ancient times humans have been keen to improve their food taste by using natural or processed additives for example in Iraq people used to add stachys pseudopinardii to legumes and use of seidlitzia rosmarinus instead of sodium bicarbonate in the preparation of legumes and add Rhus coriaria to entremets and meat. This study investigated the anti-microbial activity of aqueous extract of the three plants against some bacteria and fungus 100, 500, 1000 mg/mL were the concentration which used in this study, Rhus coiaria has the highest activity than stachy pseudopinardii finally Seidlitzia romarinus.Keyword: Natural additives, biological, activity, bacteria, fungus.
Age Gender and Site Effect on Immunohistochemical Expression of TGF-β1 and IFN-γ in Hereditary Gingival Fibromatosis Ali Omran Mousa
Journal of Global Pharma Technology Volume 11 Issue 2: 2019
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Abstract

Back ground: Gingiva as other part of oral cavity has been effected with hereditary diseases. When navigate in the jungle of gingival disease hereditary gingival fibromatosis will appeared as vague hereditary condition and the pathogeneses of disease is not clearly understood.  Clinically it’s characterized by massively increasing in gingival tissue mass, which appeared more fibrous.  Transforming growth factor beta 1 (TGF-β1) is growth factor which had critical role in pathogeneses of (HGF) together with interferon gama (IFN-γ) which inflammatory cytokines the level of these cytokines may be changed according to gender, age or site distribution (generalized, localized). Aim:  To evaluate the level of TGF-β1and IFN-γ immunohistochemically in hereditary gingival fibromatosis according gender, age and site distribution. Methods: Immunohistochemistry for detection of TFG-β1 and IFN-γ in paraffin embedded tissue sections for 17 blocks of hereditary gingival fibromatosis. Result: Non-significant difference of TGF-β1 according to gender, age and site in .Also Non- significant difference of INF -γ according to gender and site. On other hand significant difference of INF-γ according to age. Conclusion: Age, gender and site have no effect on expression of TGF-β1 in hereditary gingival fibromatosis; same findings were for IFN-γ except the age which has an obvious effect on IFN-γ expression.Keywords: Hereditary Gingival Fibromatosis.
Evaluation of Antioxidant Efficiency of Nanosized Quercetin: An In Vitro Study Ghassan M. Sulaiman
Journal of Global Pharma Technology Volume 12 Issue 01
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Abstract

Quercetin is a bioactive compound that is widely used in botanical medicine due to its powerful antioxidant activity. This work aims at encapsulated of quercetin into PLGA nanoparticles by using the nano participation technique. Following by the valuation of their functionality as antioxidant activity. Quercetin and quercetin nanoparticles by using straight forward in vitro free radical scavenging systems including DPPH (1,1-diphenyl-2-picryl hydrazyl) free radical-scavenging assay and hydrogen peroxide radical scavenging. Quercetin nanoparticles showed strong scavenging effects against DPPH, hydrogen peroxide and this effect was more potent than pure quercetin. The scavenging activity of quercetin nanoparticles was concentrations dependent in the range of 4-12 µg mL-¹ showing maximum activity of 90% at 12 µg- mL-¹in similar way to Vit.C which was used as positive control. In conclusion, this work displayed that quercetin exhibited antioxidant activity and could be considered as a source of antioxidants from nature.Keywords: Quercetin nanoparticles, Antioxidants, DPPH, DNA damage.
Typing of Acinetobacter baumannii Isolates from some Iraqi Children infected with Head Lice Eman N. Najii
Journal of Global Pharma Technology Volume 9 Issue 10
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Abstract

Head lice invasion a worldwide health care problem, which obligatory human hematophagous ectoparasites belong to pediculide family, it caused by pediculus humans capitis [1] in fact the USA was recorded 6-12 million of head lice invasion appeared every year [2].

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