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The Journal of Society Medicine (JSOCMED)
Published by PT. CoinReads Media Prima
ISSN : -     EISSN : 29645565     DOI : https://doi.org/10.47353/jsocmed.v2i1
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience
The Journal of Society Medicine (JSOCMED) | ISSN (e): 2964-5565 is a leading voice in the Indonesia and internationally for medicine and healthcare. Published continuously, JSOCMED features scholarly comment and clinical research. JSOCMED is editorially independent from and its The Editor-in-Chief (EIC) is Prof. dr. Aznan Lelo, PhD, SpFK. JSOCMED offers many attractive features for authors, including free online access to all research articles, online publication ahead of print, and online responses to articles published as Quick Comments. In addition, as befitting a publication of the Journal of Society Medicine, JSOCMED implements best practice in scientific publishing with an open peer review process, declarations of competing interests and funding, full requirements for patient consent and ethical review, and statements of guarantorship, contributorship, and provenance.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 5 Documents
 1 
Search results for , issue "Vol. 3 No. 7 (2024): July" : 5 Documents clear
The Aryl Hydrocarbon Receptor (AhR) Level Based on Age and Clinical Type of Melasma Danil, Rezkyana; Jusuf, Nelva Karmila; Putra, Imam Budi
Journal of Society Medicine Vol. 3 No. 7 (2024): July
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i7.153

Abstract

Introduction: Melasma is the most common pigmentation condition on the face due to excessive melanin production and release. The main predisposing factor for melasma is UV exposure. Aryl Hydrocarbon Receptor (AhR) is a ligand-dependent transcription factor that regulates the expression of a very large number of target genes in humans. Facial hyperpigmentation is increased in people living in air-polluted areas with particulate matter2.5  (PM2.5) concentrations. Dioxin compounds contained in PM2.5  can activate AhR signaling. This study aims to determine the aryl hydrocarbon receptor (AhR) level based on age and clinical type of melasma. Methods: This study was an observational study with a cross-sectional design of 30 women with melasma at Prof. CPL Hospital. This study was conducted after obtaining ethical clearance from the Research Ethics Commission of the University of North Sumatra and has obtained permission from the research field of Prof. Chairuddin Panusunan Lubis Hospital. All subjects underwent history taking, physical examination, dermatological examination, and blood sampling to assess AhR levels by ELISA test. Data were analyzed with Chi square test to assess AhR levels based on age, and to assess AhR levels based on clinical type of melasma with Kruskal Wallis test. Results: This study shows that the majority of melasma age is 41-50 years with the highest mean AhR level is 882,61 ng/mL, while the lowest AhR level is in the age range of 20-30 years with a mean of 271,5 ng/mL. Chi square test showed that there was a significant relationship between AhR levels and age (p < 0,001). The highest mean AhR levels in melasma subjects were centrofacial type with a mean of 795,50 ng/mL, while the lowest mean AhR levels were found in melasma subjects with malar type with a mean of 623,36 ng/mL. The Kruskal Wallis test showed that there was no significant difference in AhR levels based on the clinical type of melasma (p = 0,930). Conclusion: That increased the age, the highest AhR levels. The highest average AhR level was centrofacial type of melasma. There was no significant difference in AhR levels based on the clinical type of melasma.
The Relationship of Blood Eosinophils Levels with Degree of Exacerbation in COPD Patient at Usu General Hospital Deneuve, Olivia Monica; Pradana, Andika; Tarigan, Amira P.
Journal of Society Medicine Vol. 3 No. 7 (2024): July
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i7.155

Abstract

Introduction: During acute exacerbations of chronic obstructive pulmonary disease (COPD), blood eosinophil count has the potential to predict treatment response. Nevertheless, there hasn't been enough research done to determine whether blood eosinophil numbers in a stable state can forecast an eosinophilic exacerbation. Methods: This study was a retrospective cohort analysis performed July-August 2022 to July-August 2023. Subject were 44 COPD patients who were treated at the outpatient clinic. Blood samples measured blood eosinophil levels. We determined an absolute cut-off point for blood eosinophil count at stable COPD in order to identify the rate of exacerbation. Results: Based on the Kruskal-Walli’s test, there was a significant relationship between blood eosinophils and the level of exacerbations in COPD patients (p value = 0.003). Conclusion: We established a relationship between the rate of exacerbation and blood eosinophil counts during stable COPD. The rate of exacerbation and eosinophil counts showed a strong positive relationship. Our findings should be confirmed by prospective and further research in different populations.
Correlation between Tumor Location and Size in Intracranial Tumor Patients and Seizure Types Kurniawan Ritonga, Ilham; Kemala Nasution, Irina; Muhammad Iqbal, Kiki
Journal of Society Medicine Vol. 3 No. 7 (2024): July
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i7.156

Abstract

Introduction: Brain tumors are rare with a worldwide incidence of 296,851 cases worldwide. A large tumor size indicates a long duration of silent growth, allowing more time for seizures to develop. The aim of this study was to determine the correlation between tumor location and size in patients with intracranial tumors and the type of seizure. Methods: This study used a cross-sectional design in patients who encountered seizure and had been diagnosed with intracranial tumors undergoing treatment at H. Adam Malik Hospital Medan We used Fisher Exact analysis test to determine the relationship of seizure generation type in intracranial tumor patients based on tumor location and Chi-Square analysis test to determine the relationship of seizure generation type in intracranial tumor patients based on tumor size. This study included 43 patients with intracranial tumors accompanied by seizures. Results: Statistical analysis showed insignificant results between tumor location and type of seizure with  p value of 0.543 was obstained, indicating that the relationship between tumor location and type of seizure was not significant (p < 0.05). The results of statistical analysis showed a significant result between tumor size and type of seizure with p value of 0.048. Conclusion: There was no association between tumor location in intracranial tumor patients and the type of seizure. However, there was a relationship between tumor size in intracranial tumor patients and the type of seizure.
The Relationship between Red Blood Cell Distribution Width and Coronary Artery Lesion Severity In Acute Myocardial Infarction Patients with Non-Elevation of ST-Segment (IMA-NEST) at Haji Adam Malik Hospital Alfuadi, T. Rifki Mirza; Mukhtar, Zulfikri; Sitepu, Andika
Journal of Society Medicine Vol. 3 No. 7 (2024): July
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i7.157

Abstract

Introduction: Red cell distribution width (RDW), a measure of erythrocyte size variability, is associated with acute inflammation. Elevated RDW predicts adverse outcomes in cardiovascular diseases like acute myocardial infarction. This study investigated the relationship between RDW and coronary lesion severity, assessed by the SYNTAX Score, in patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) undergoing coronary angiography. Methods: This retrospective analytical study included NSTE-ACS patients who underwent coronary angiography at H. Adam Malik General Hospital Medan. Baseline characteristics, laboratory parameters (including RDW), and angiography results were collected. The association between RDW and SYNTAX Score was analyzed. ROC/AUC curve analysis assessed RDW's predictive ability for coronary lesion severity, determining sensitivity and specificity. Results: In 160 patients, RDW was significantly associated with SYNTAX Score (p<0.001). TIMI score, GRACE score, and number of involved arteries also correlated with lesion severity. Conclusion: RDW is a promising predictor of coronary lesion severity in NSTE-ACS patients undergoing coronary angiography.
The Relationship between Heart Rate Recovery and Rate Pressure Product on Coronary Lesion Severity Using Syntax Score in Stable Angina Pectoris Patients at Haji Adam Malik Hospital Medan Adam, Faisal; Andra, Cut Aryfa; Lubis, Hilfan Ade Putra
Journal of Society Medicine Vol. 3 No. 7 (2024): July
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i7.158

Abstract

Introduction: RPP is used as a marker of cardiac function. RPP reflects the function of the heart in fulfilling oxygen demand stably and continuously during activity. Slow decline of HRR is associated with risk factors for atherosclerosis, similar to hypertension and dyslipidaemia There has not been much research on HRR and RPP in coronary heart disease. The aim of this study is to examine the relationship between RPP and syntax score in stable coronary heart disease. Methods: This study is an observational analytic study with a cross sectional design to determine the relationship between HRR and RPP to the severity of coronary lesions using the syntax score in stable angina pectoris patients. Sampling was carried out at the Haji Adam Malik Hospital Medan from February. HRR and RPP scores were obtained from cardiac exercise testing and syntax scores were obtained from coronary angiography after validation by an interventionist. EF data were taken from echocardiography results validated by consultant echocardiographers. Statistical data analysis using computer statistical tools, p value <0.05 was considered statistically significant. Results: From angiographic data in samples with syntax score ≥ 23, there were 23 (100%) LAD, 21 (91.3%) LCx, and 22 (95.7%) RCA involvement. In samples with Syntax score < 23, there were single vessel lesions as many as 11 (40.07%), two vessels as many as 12 (44.4%), and three vessels as many as 4 (14.8%). From the test results, there was a significant relationship between HRR and RPP and SYNTAX score with a p value <0.05 (<0.001) in both variables. Conclusion: There was a significant association in HRR scores and RPP scores between groups with SYNTAX scores ≥ 23 and SYNTAX scores < 23.

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