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Fahruddin Kurdi
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INDONESIA
Jurnal Kesehatan Komunitas Indonesia
Published by Al-Hijrah Indonesia
ISSN : 29853435     EISSN : 25032801     DOI : https://doi.org/10.58545/jkki
Core Subject : Health, Social,
Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health
The Jurnal Kesehatan Komunitas Indonesia (JKKI) is an open access scientific journal managed by EBSINA and published by Al-Hijrah Indonesia. JKKI focuses on public health and nursing research, epidemiology, pharmacy, reproductive health, health management, environmental health, health promotion, occupational safety, community nutrition, health policy, and others related to health in the community. JKKI welcomes original articles, review articles, and case studies on various professional health services. Health workers are subjects at JKKI, but writers outside the health subject are also welcome to be able to send articles as long as the article is within the scope of JKKI, especially its implications for public health. The Indonesian Community Health Journal (JKKI) is published in April, August and December.
Arjuna Subject : Kedokteran - Kesehatan Masyarakat, Kesehatan Lingkungan dan Pekerjaan
Articles 133 Documents
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Micronutrient Deficiency and Autophagy Dysregulation in Pulmonary Tuberculosis Pathogenesis: A Systematic Review Salma Winda Aufa; Delmi Sulastri
Jurnal Kesehatan Komunitas Indonesia Vol 6 No 2: August 2026
Publisher : Al-Hijrah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58545/jkki.v6i2.778

Abstract

Pulmonary tuberculosis remains a critical global health burden, with Indonesia ranking second in the world for the highest TB burden. Autophagy is an essential innate immune mechanism for eliminating intracellular Mycobacterium tuberculosis (Mtb) in macrophages, but it is susceptible to dysregulation by micronutrient deficiencies, which are highly prevalent in populations with active TB. This systematic review aims to synthesize scientific evidence on the effects of deficiencies in vitamin D, vitamin A, zinc, and selenium on the dysregulation of the autophagy pathway and its implications for the pathogenesis of pulmonary tuberculosis. Literature searches were performed in PubMed and ScienceDirect for studies published from 2006 to 2025, using a combination of MeSH terms and free-text keywords. A total of 11 studies were included in the final synthesis. The results of the synthesis indicate that vitamin D deficiency inhibits the transcription of autophagy genes (LC3, Beclin-1, ATG5) by disrupting VDR signaling. Combined zinc and vitamin D deficiency reduces autophagy capacity by up to 85% and correlates with worse clinical outcomes of TB. Specifically, zinc and vitamin D deficiencies act synergistically to inhibit autophagy, representing the most significant interaction. Micronutrient deficiencies were shown to dysregulate autophagy through distinct yet synergistic molecular pathways, facilitating Mtb persistence and exacerbating the pathogenesis of pulmonary TB. Micronutrient supplementation holds potential as an adjuvant host-directed therapy strategy in the management of pulmonary tuberculosis.
Predicting E-Cigarette Adoption Among University Students: A Theory of Planned Behavior Approach in a Collectivist Context Siti Fatimah; Chandra Kartika Dewi; Adila Nur'aini Az Zahra; Muhammad Yasin Al-Fath
Jurnal Kesehatan Komunitas Indonesia Vol 6 No 2: August 2026
Publisher : Al-Hijrah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58545/jkki.v6i2.853

Abstract

E-cigarette use has become an increasingly prevalent trend among university students, accompanied by ongoing debates regarding its long-term health effects. This trend is linked to the perception that e-cigarettes contain lower levels of nicotine and otherharmful substances compared to conventional tobacco cigarettes. This study aimed to examine the factors influencing students' adoption of e-cigarettes by applying the Theory of Planned Behavior(TPB). The research was conducted among students at UIN Sunan KalijagaYogyakarta. Data were collected via an online survey distributed through the university's academic system, with respondents recruited through accidental and snowball sampling. A total of 105 students completed the questionnaire and were included in the analysis. The results showed that the TPB model explained only 12.1% of the variance in students' intention to adopt e-cigarettes, a notably low value indicating the influence of factors beyond the standard TPB constructs. Attitude toward behavior (β= 0.251) and perceived behavioral control (β= 0.169) were positively associated with intention, whereas subjective norm was negatively associated. This finding indicates that social referents tended to discourage rather than promote the adoption of e-cigarettes. The attitude toward behaviorconstruct was primarily driven by items reflecting social acceptance rather than health-risk perceptions. These findings suggest that students' adoption of e-cigarettes as an alternative to conventional tobacco cigarettes is influenced more by social factors than by perceptions of reduced health risks
Kingella denitrificans as a Mimicker of Neisseria meningitidis in Carriage Surveillance Delly Chipta Lestari; Puspa Andhia Kemalasari; Rifka Kamila; Chesya Ejoli; Wisnu Tafroji; Ibnu Agus Ariyanto; Selvi Nafisa Shahab; Bebby Shelby; Alana Arumsari
Jurnal Kesehatan Komunitas Indonesia Vol 6 No 2: August 2026
Publisher : Al-Hijrah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58545/jkki.v6i2.871

Abstract

Background: Meningitis caused by Neisseria meningitidis remains a significant public health concern. A carriage study is crucial for understanding the distribution of Neisseria meningitidis serogroups in the community. The presence of Kingella denitrificans may lead to misidentification as N. meningitidis due to phenotypic similarity on blood agar. However, the prevalence of K. denitrificans in nasopharynx and oropharynx remains unclear. Objective: This study aimed to determine the prevalence of K. denitrificans as a mimicker of N. meningitidis in a carriage surveillance setting and to evaluate the role of MALDI-TOF MS in ensuring accurate bacterial identification. Methods: A cross-sectional study was conducted from September to December 2025 among unvaccinated adults in Jakarta with meningococcal disease. Oropharyngeal and nasopharyngeal swabs were collected and cultured on VCNT-supplemented blood agar. Preliminary identification was performed using colony morphology, Gram staining, and oxidase and catalase tests. Definitive identification was carried out using MALDI-TOF MS. Results: Among 228 participants, 11 (4.8%) carried Kingella spp. in the nasopharynx and/or oropharynx. All carriers were females aged 19–33 years (median age: 25 years). The isolates exhibited colony morphology similar to N. meningitidis, potentially leading to misidentification. However, they could be differentiated by their Gram staining morphology and catalase test results. MALDI-TOF MS identified 5 of 11 isolates (45.5%) as K. denitrificans with high-confidence log scores. Conclusion: K. denitrificans phenotypically might mimicked N. meningitidis in carriage surveillance but can be distinguished with Gram staining. The integration of MALDI-TOF MS is essential to improve diagnostic accuracy and prevent false-positive results. Further studies are needed to assess the feasibility of implementing this technology in resource-limited settings.

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