cover
Contact Name
Lantip Rujito
Contact Email
smhj@unsoed.ac.id
Phone
+6281343880797
Journal Mail Official
smhj@unsoed.ac.id
Editorial Address
Address: Jl. Dr. Gumbreg, Medical Street, Mersi, Purwokerto Central Java 53122 Telp. (0281) 622022, Fax. (0281) 624990
Location
Kab. banyumas,
Jawa tengah
INDONESIA
Medical and Health Journal
ISSN : -     EISSN : 28073541     DOI : https://doi.org/10.20884/1.mhj.2023.2.2.8053
Core Subject : Health,
Medical and Health Journal (EISSN. 2807-3541) is containing various articles/ manuscripts in the forms of research article, systematic reviews, case reports in the field of medicine focusing on basic medicine, clinical medicine, biomedical sciences, medical biotechnology, and public health. This journal is published by Universitas Jenderal Soedirman, Purwokerto, Indonesia.
Articles 152 Documents
Pediatric Submandibular Abscess: Diagnostic Challenges and Comprehensive Management – A Literature Review Rein, Virjinea Hawani; Wardhana, Arroyan; Rahmi, Hastuti
Medical and Health Journal Vol 5 No 2 (2026): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.5.2.18252

Abstract

Submandibular abscess in children is a rare deep neck space infection but can be fatal if diagnosis and management are delayed. Most cases (70–85%) originate from odontogenic infections of the mandibular molars, with Staphylococcus aureus and Streptococcus viridans as the predominant pathogens. This article reviews the etiology, early diagnosis, and management of pediatric submandibular abscesses based on recent literature (2020–2025) from Google Scholar, PubMed, and ScienceDirect. Anatomical and immunological differences in children lead to faster infection spread with nonspecific early symptoms; therefore, careful clinical examination and the use of CT scans or ultrasonography are crucial for early diagnosis. Management includes airway stabilization, culture-based broad-spectrum antibiotics, and timely surgical drainage. Multidisciplinary collaboration among dentists, ENT specialists, and pediatric anesthesiologists is essential to reduce morbidity and mortality. Prospective studies are needed to evaluate the effectiveness of minimally invasive approaches and current antibiotic resistance patterns in children. Early diagnosis, rational therapy, and interdisciplinary cooperation remain the key factors in achieving successful outcomes in pediatric submandibular abscess management.
Exclusive Breastfeeding and the Risk of Complicated Pneumonia in Toddlers: A Literature Review Angelita, Puja Rizkina; Sandhi Parwata, Wayan Sulaksmana; Kurniawaty, Titi Pambudi
Medical and Health Journal Vol 5 No 2 (2026): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.5.2.18385

Abstract

Pneumonia is a leading cause of morbidity and mortality in children under five worldwide. The World Health Organization (WHO, 2019) reports that pneumonia accounts for approximately 14% of all infant deaths, with more than 740,000 deaths per year. In Indonesia, the prevalence of pneumonia in infants remains high, including in West Nusa Tenggara Province, which recorded 32,128 cases in 2023, with 4,183 cases in West Lombok Regency. One protective factor believed to reduce the risk of pneumonia is exclusive breastfeeding during the first six months of life. Breast milk contains various immunological components such as secretory immunoglobulin A (sIgA), lactoferrin, lysozyme, and oligosaccharides, which play a role in protecting against lower respiratory tract infections (Lyons et al., 2020; Moraes-Pinto et al., 2021). This literature review was compiled using a narrative literature review method using relevant national and international sources, including journals from PubMed, ScienceDirect, and official WHO and UNICEF reports. The literature reviewed was published between 2015 and 2024, focusing on the relationship between exclusive breastfeeding and the incidence of pneumonia in toddlers. The analysis was conducted descriptively and thematically, reflecting the content of previous studies. Based on the study results, exclusive breastfeeding has been shown to have a significant protective effect against the incidence of pneumonia. Infants who are not exclusively breastfed have a two to five times higher risk of developing lower respiratory tract infections (Popovsky, E.Y. and Florin, T.A., 2021). A global study by Victora et al. (2016) found that exclusive breastfeeding reduces the risk of severe pneumonia by up to 64% and has the potential to prevent 820,000 child deaths annually. However, the incidence of complicated pneumonia is also influenced by other factors such as nutritional status, basic immunizations, exposure to cigarette smoke, and home environmental conditions (Dean & Florin, 2018; Saunders, 2017). Exclusive breastfeeding plays a crucial role in preventing pneumonia in toddlers through immunological mechanisms and protection of the respiratory mucosa. However, because pneumonia is a multifactorial disease, the effectiveness of exclusive breastfeeding needs to be supported by improved nutritional status, immunization coverage, and environmental improvements. Comprehensive promotive and preventive efforts are needed to reduce the incidence of pneumonia and its complications in the community.
Overview of Adherence Diet Management in Type 2 Diabetes Mellitus Patients at Kabila Public Health Center Jusuf, Nurain; Yusuf, Zuhriana K.; Arsad, Sitti Fatimah
Medical and Health Journal Vol 5 No 2 (2026): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.5.2.18802

Abstract

Diet is a crucial part of managing type 2 diabetes mellitus. One way to achieve this is by following the 3J (Type, Amount, and Schedule) of dietary management. Dietary adherence remains variable, even though patients receive regular education through the PROLANIS program. Dietary non-compliance can result in uncontrolled blood glucose levels and an increased risk of chronic complications. This study aims to describe the 3J diet management compliance in type 2 Diabetes Mellitus patients at the Kabila Community Health Center. This study used a descriptive quantitative design. The research variable was 3J diet management compliance. The population was 289 type 2 DM patients, and a sample of 75 respondents selected using accidental sampling techniques. The instrument used was a 3J diet compliance questionnaire. Data were analyzed univariately using frequency distribution to describe the level of respondent compliance. The results of the study based on indicators, compliance with the type of diet showed that 45 respondents (60.0%) were non-compliant, the number of calories showed that 41 respondents (54.7%) were non-compliant, while the meal schedule showed that 47 respondents (62.7%) were compliant. These findings illustrate that most patients still experience difficulties in managing the type and amount of food, even though they have been quite good at complying with the meal schedule. The Community Health Center is advised to conduct monitoring activities and further research is suggested to develop peer tutoring-based intervention methods.
Quality of Life Among Older Adults Living with HIV: A Literature Review Saniyya, Shinta Elrica; Ardianto, Nova; Trisiswati, Maya
Medical and Health Journal Vol 5 No 2 (2026): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.5.2.18831

Abstract

Advances in antiretroviral therapy have extended the life expectancy of people living with HIV, leading to a growing population of older adults with this condition who face age-related biological decline alongside persistent psychosocial pressures that may reduce their quality of life. This review was conducted to describe the quality of life of older adults living with HIV and to examine the psychosocial factors influencing it based on research published in the past five years. A literature review approach was employed by searching several online databases and selecting studies published between 2019 and 2025 that focused on quality of life and psychosocial aspects among individuals aged 50 years and older living with HIV. Six studies met the inclusion criteria and show a consistent pattern indicating that the quality of life of older adults with HIV is shaped by psychosocial conditions such as stigma, depression, and limited social support, all of which contribute to diminished well-being. Conversely, protective factors such as resilience and community support play a crucial role in enhancing psychological health and improving overall quality of life. These findings highlight that the well-being of older adults living with HIV is strongly influenced by their psychosocial environment, and emphasize the need for interventions that strengthen social support and foster resilience to promote better quality of life within this population.
Synthesizing The Evidence: TP53 Mutations as a Prognostic and Predictive Biomarker in Breast Cancer Chuvita, Laila; Wibowo, Syifa Sofia
Medical and Health Journal Vol 5 No 2 (2026): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.5.2.19146

Abstract

The journey to personalize breast cancer therapy increasingly navigates the complex landscape of somatic TP53 mutations, the most frequent genetic drivers of this disease. Moving beyond a simple prognostic badge, we now understand these mutations create a spectrum of clinical behaviors, deeply influenced by their specific functional impact and, critically, by their genetic companions. A systematic literature review was conducted across three major electronic databases: ScienceDirect, ProQuest, and Scopus. The search was restricted to peer-reviewed journal articles published in English between 2021 and 2024 to ensure the inclusion of recent evidence. The confluence of TP53 and PIK3CA mutations stands out as a devastating synergy that heralds a tumor phenotype with profound resistance to common chemotherapy regimens, especially taxanes, and the direst survival outcomes. This genetic context also subtly reshapes responses to HER2-targeted drugs, revealing that TP53's influence is both powerful and context-dependent. A more nuanced profiling, one that accounts for these critical genetic interactions, is no longer a future aspiration but a present necessity. These findings collectively advocate for the integration of comprehensive molecular profiling, including nuanced TP53 and PIK3CA assessment, into clinical decision-making.
Association Between Lumbar Vertebral MRI Findings and Neuropathic Pain in Patients With Low Back Pain at Prof. Dr. Margono Soekarjo General Hospital Rizki Adiputri, Hening Yanita; Kuncoro, Prasetyo Tri; Gunarto, Untung; Pratama, Tisna Sendy; Permatasari, Octavia; Wijayana, Kamal Agung; Setyanto, Muhamad Rifqy
Medical and Health Journal Vol 5 No 2 (2026): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.5.2.19165

Abstract

Background: Low back pain (LBP) is a common musculoskeletal condition that may be accompanied by neuropathic pain due to irritation or compression of lumbar neural structures, often associated with structural abnormalities detected on MRI. Objective: This study aimed to assess the association between lumbar MRI findings and neuropathic pain in patients with LBP at Prof. Dr. Margono Soekarjo General Hospital. Methods: An analytical observational study with a cross-sectional design was conducted involving 68 patients, using lumbar MRI data and neuropathic pain screening with the ID Pain questionnaire. Associations were analyzed using Chi-square tests and multivariate logistic regression with a significance level of p < 0.05. Results: The most frequent MRI findings are herniated nucleus pulposus (85.3%), spinal stenosis (57.4%), spondylosis (38.2%), and spondylolisthesis (19.1%), while neuropathic pain is identified in 66.2% of patients. Significant associations are observed between neuropathic pain and all MRI findings, with lumbar spinal stenosis identified as the strongest predictor. Conclusion: Lumbar MRI abnormalities are significantly associated with neuropathic pain in patients with LBP, and spinal stenosis represents the most influential factor, emphasizing the importance of radiological evaluation in the management of LBP with neuropathic components.
Basic Immunization Status and Incidence of Measles Among Toddlers in Working Area of Limboto Public Health Center, Gorontalo Regency Katili, Asra wati; Ibrahim, Sri Andriani; Mohamad, Rini Wahyuni
Medical and Health Journal Vol 5 No 2 (2026): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.5.2.19301

Abstract

Measles (campak) is a contagious disease that remains a health problem among toddlers and contributes to high morbidity and mortality rates in children. Globally, measles cases increased from 170,000 cases in 2022 to over 320,000 cases in 2023, with deaths occurring mainly in children who did not receive complete immunization. This condition indicates that basic immunization plays an important role in measles prevention. In Gorontalo Province, measles and rubella cases are still found in several districts/cities, with Gorontalo Regency having the highest number of cases. One of the preventive efforts is the provision of complete basic immunization to enhance immunity against the disease. This study aimed to determine the relationship between basic immunization status and the incidence of measles in toddlers in the working area of Limboto Health Center, Gorontalo Regency.This study was a quantitative study with an analytic observational design using a cross-sectional approach. The study population consisted of all toddlers in the working area of Limboto Health Center, Gorontalo Regency, with a total sample of 60 toddlers taken using a total sampling technique. The research instrument used a checklist sheet. Data analysis was conducted univariately and bivariately using the Chi-Square test. The study results showed that there was a relationship between basic immunization status and the incidence of measles in toddlers (p-value < 0.05). The conclusion of this study is that there is a relationship between basic immunization status and the incidence of measles in toddlers. Therefore, it is recommended that healthcare workers increase education for parents and improve complete basic immunization coverage as a preventive measure against measles in toddlers.
Phytochemical Characterization of the Chloroform Extract of Foeniculum vulgare Mill. Leaves with Implications for Antiparasitic Agent Development Ihtiaringtyas, Suci; Sari, Octavia Permata; Susiawan, Lieza Dwianasari; Firinda, Rizma Haidif; Amalia, Ary Nahdiyani; Fuady, Rhovee Ilmiawan
Medical and Health Journal Vol 5 No 2 (2026): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.5.2.19358

Abstract

The development of antiparasitic agents derived from natural products continues to receive considerable attention due to increasing resistance and limitations of conventional therapies. This study aimed to examine the phytochemical profile of the chloroform extract of fennel leaves (F. vulgare Mill.) as a basis for antiparasitic agent development. The extract was obtained using a maceration method and analyzed using thin layer chromatography. Qualitative analysis was conducted based on the observation of visible spots after spraying with appropriate visualization reagents, while supporting analysis was performed based on the calculation of retention factor values for the detected spots. The results revealed the presence of several major groups of secondary metabolites, including flavonoids, terpenoids, alkaloids, and phenolic compounds, as indicated by specific color changes and retention factor values. The diversity of these metabolites suggests the possible involvement of multiple biochemical pathways related to antiparasitic mechanisms. Overall, the phytochemical profile of the chloroform extract of fennel leaves provides important preliminary data to support further research on natural product–based antiparasitic agents.
Effect of Level 1 Progressive Mobilization Therapy on Oxygen Saturation in Patients Diagnosed with Respiratory Failure in ICU of Prof. Dr. H. Aloei Saboe Hospital, Gorontalo City Patilima, Roni Mohammad A. R.; Yusuf, Zuhriana K.; Yusuf, Nur Ayun R.
Medical and Health Journal Vol 5 No 2 (2026): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.5.2.19371

Abstract

Level 1 progressive mobilization therapy is a non-pharmacological therapy using a complementary approach that can affect oxygen saturation. The purpose of this study was to determine the effect of level 1 progressive mobilization therapy on oxygen saturation in patients diagnosed with respiratory failure in the ICU of Prof. Dr. H. Aloei Saboe Regional Hospital, Gorontalo City. This study is a quantitative study with a quasi-experimental design using a one-group pre-post test design approach . which only involved one treatment group, namely the group of patients diagnosed with respiratory failure who were given level 1 progressive mobilization therapy intervention. The study population was 51 patients with an accidental sampling technique with a sample size of 45 patients. This research instrument used the SOP for level 1 progressive mobilization and an oxygen saturation observation sheet. Data analysis used the Wilcoxont-test. The results of the study obtained a p-value of 0.000 (α <0.05) meaning that there was an effect of level 1 progressive mobilization therapy on oxygen saturation in patients with respiratory failure at Prof. Dr. H. Aloei Saboe Regional Hospital, Gorontalo City. Level 1 progressive mobilization plays a crucial role in improving respiratory function, accelerating recovery, and maintaining the body's overall physiological balance. This research is expected to serve as a reference for providing nursing care, particularly level 1 progressive mobilization exercises for patients diagnosed with respiratory failure, as an effort to prevent decreased oxygen saturation.
The Relationship Between Peer Group Support and Snack Choosing Behavior Among School-Aged Children at Limboto 1 Public Elementary School H. Djafar, Stevilia Marcella; Hafid, Ridha; Mohamad, Rini Wahyuni
Medical and Health Journal Vol 5 No 2 (2026): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.5.2.19372

Abstract

School-age children, aged 6 to 12, are at a crucial developmental stage, where school experiences are a key aspect of their lives. Children's snack selection behavior is influenced by two factors: personal factors such as knowledge and habits, and environmental factors such as the role of family, peers (peer group), and school conditions. Peer group support is a form of social support provided by individuals within friendships to help and strengthen each other. This study aims to determine the relationship between peer group support and snack choice behavior among school-aged children at Limboto 1 Public Elementary School. This study used probability sampling, a technique that provides an equal opportunity for each member of the population to be selected as a sample. The method used in this study was proportionate stratified random sampling, a sampling technique used when the population has non-homogeneous members and is divided into strata with varying numbers. The results above indicate a relationship between peer group support and snack choice behavior among school-aged children. This was confirmed by statistical testing using Chi Square, which yielded a p-value of 0.009 <α = 0.05.