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Lantip Rujito
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Medical and Health Journal
Published by Universitas Jenderal Soedirman
ISSN : -     EISSN : 28073541     DOI : https://doi.org/10.20884/1.mhj.2023.2.2.8053
Core Subject : Health,
Medicine & Pharmacology
Medical and Health Journal (EISSN. 2807-3541) is containing various articles/ manuscripts in the forms of research article, systematic reviews, case reports in the field of medicine focusing on basic medicine, clinical medicine, biomedical sciences, medical biotechnology, and public health. This journal is published by Universitas Jenderal Soedirman, Purwokerto, Indonesia.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 188 Documents
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Expectative Management of a Late-Diagnosis Twin Reversed Arterial Perfusion Sequences (TRAPS) - A Rare Case Report Velika Devina; Herman Sumawan; Muhammad Alamsyah Aziz; Mohamad Fakih
Medical and Health Journal Vol 5 No 2 (2026): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.5.2.19785

Abstract

Twin Reversed Arterial Perfusion Sequence (TRAPS) is a rare and severe complication unique to monochorionic twin pregnancies, characterized by retrograde perfusion of a nonviable acardiac twin by a structurally normal pump twin. Management of TRAPS diagnosed in late gestation remains controversial due to limited interventional options and an unpredictable clinical course. While early fetal intervention is generally recommended, evidence supporting expectant management in late-diagnosed cases, particularly in resource-limited settings, remains scarce. We report a 31-year-old gravida 2, para 1 woman with a monochorionic diamniotic twin pregnancy complicated by TRAPS, who was referred to a maternal–fetal medicine clinic at 29–30 weeks of gestation. Given stable pump twin hemodynamics, late gestational age, and unavailability of fetal therapy, expectant management with intensive ultrasound surveillance was pursued. At 32 weeks, signs of evolving cardiac compromise prompted delivery by cesarean section. The pump twin survived with prematurity-related complications and was discharged in stable condition. This case highlights that expectant management may be a reasonable option in carefully selected late-diagnosed TRAPS cases when fetal therapy is unavailable, provided that close surveillance and timely delivery are ensured.
The Role of Rumination in University Students’ Mental Health: A Mediation Analysis of Depression and Anxiety Nisaul Maghfiroh; Ernasiwi Astri Oktavilia; Arfi Nurul Hidayah; Isran Kamal; Hajid Rahmadianto Mardihusodo; Muhammad Zaenuri Syamsu Hidayat
Medical and Health Journal Vol 5 No 2 (2026): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.5.2.19800

Abstract

This study examined the relationship between rumination and mental health among university students by testing the mediating roles of depression and anxiety. Rumination refers to a repetitive and passive focus on negative experiences and emotions that may influence psychological functioning. A quantitative correlational design was employed. A total of 113 students completed the Ruminative Response Scale (RRS), Beck Depression Inventory-II (BDI-II), Beck Anxiety Inventory (BAI), and General Health Questionnaire (GHQ-12). Parallel mediation analysis indicated that rumination significantly predicted depression (β = .6197, p < .001) and anxiety (β = .5830, p < .001). Depression significantly predicted mental health (β = .2893, p = .025), whereas anxiety was not a significant predictor (β = .1186, p = .343). The direct effect of rumination on mental health was not significant (β = −.0940, p = .427), nor was the total effect (β = .1544, p = .098). However, the indirect effect through depression was significant (β = .1793, p = .031; 95% CI [.00464, .0957]), whereas the indirect path through anxiety was not significant (β = .0692, p = .347). These findings indicate that depression fully mediates the relationship between rumination and mental health. Thus, the influence of rumination on students’ mental health primarily operates through increased depressive symptoms.
ALT and AST Enzyme Levels in Chronic Kidney Disease Patients Undergoing Hemodialysis Najla Nur Asyifa; Ariadi Humardhani; Syafruddin A. R. Lelosutan
Medical and Health Journal Vol 6 No 1 (2026): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.6.1.17853

Abstract

Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were commonly used as indicators of liver function. In patients with chronic kidney disease (CKD), particularly those undergoing hemodialysis (HD), levels of these enzymes were often found to be lower than in non-HD patients. This literature review aimed to examine changes in AST and ALT levels among CKD patients undergoing HD. Articles published between 2015 and 2025 were identified through Google Scholar and PubMed using the keywords "ALT AND AST AND Chronic Kidney Disease AND Hemodialysis." A total of nine studies met the inclusion criteria and were analyzed. Overall, AST and ALT levels were found to be consistently lower in HD patients compared with non-HD patients. Enzyme levels tended to increase following dialysis sessions, a change that was attributed to hemoconcentration and the removal of circulating enzyme inhibitors during the dialysis process. However, variation was observed across studies, which was linked to differences in dialysis protocols, timing of blood sampling, and patients' clinical conditions. These findings indicated that reduced liver enzyme levels in HD patients did not necessarily reflect normal liver function, but rather reflected dialysis-related factors and nutritional deficiencies commonly seen in this population. It was concluded that interpretation of liver function tests in CKD patients undergoing HD required careful consideration of dialysis-related variables and individual patient characteristics
Osteomeatal Complex variations and Maxillary Sinusitis: A CT-Based Cross-Sectional Study Siti Attamimi Al Ahdi; Tisna Sendy Pratama; Ary Nahdiyani Amalia; Wahyu Dwi Kusdaryanto; Ismiralda Oke Putranti
Medical and Health Journal Vol 6 No 1 (2026): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.6.1.19035

Abstract

Backgorund The osteomeatal complex (OMC) is the main drainage pathway of the paranasal sinuses, and anatomical variations, such as nasal septal deviation, may disrupt airflow and increase the risk of sinusitis; therefore, a CT Scan is the preferred modality for its evaluation. Objective: To determine the association between OMC anatomical variations and maxillary sinusitis based on head CT Scan results at Ajibarang Regional Hospital in 2024. Methodology: This analytic, observational, cross-sectional study used head CT Scan data, with OMC anatomical variations as independent variables and maxillary sinusitis as the dependent variable. Interobserver agreement was assessed using Fleiss’ Kappa, followed by univariate analysis to determine frequency distribution, and bivariate analysis using the Chi-square (χ²) test with a significance level of p < 0.05. Results: Interobserver agreement was substantial to perfect (κ = 0.76–1.00). Most patients presented with maxillary sinusitis (69.44%), and the most common anatomical variation was nasal septal deviation (52.78%), which was the only anatomical variation to show a significant association with maxillary sinusitis (p = 0.001). Conclusion: Nasal septal deviation is the only OMC anatomical variation significantly associated with maxillary sinusitis, while other variations showed no meaningful association.
Disposable Diapers and Incidence of Diaper Rash In Infants Damai Antar Suku Pakaya; Sri Andriani Ibrahim; Rini Wahyuni Mohamad
Medical and Health Journal Vol 6 No 1 (2026): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.6.1.19311

Abstract

A baby’s sensitive skin is highly susceptible to problems due to its structurally immature development. Diaper rash is a common skin problem in infants, particularly those under one year of age. This condition is characterized by redness, irritation, and even inflammation in the skin area covered by a diaper. Prolonged or frequent use of disposable diapers without proper changes can increase moisture and skin contact with urine or feces. This study aimed to determine the relationship between the use of disposable diapers and the incidence of diaper rash in infants at RSIA Sitti Khadijah Kota Gorontalo. This study employed a quantitative research design using an analytical survey method and a cross-sectional approach. The study population consisted of mothers with infants aged 0–12 months at RSIA Sitti Khadijah Kota Gorontalo who had diaper rash. The sample size was 40 respondents, and a non-probability sampling technique using total sampling was employed, meaning the entire population meeting the inclusion criteria was included in the study. Disposable diaper use was measured using a questionnaire, while the occurrence of diaper rash was assessed using an observation sheet. Data analysis was performed using the Chi-Square test, yielding a p-value of 0.001 < 0.05. These results indicate a significant association between the use of disposable diapers and the incidence of diaper rash in infants at RSIA Sitti Khadijah Kota Gorontalo. Parents need education through health education sessions led by healthcare workers particularly nurses conducted at the hospital regarding the prudent use of disposable diapers and the importance of proper infant skin care practices.
Family Socioeconomic Status and Risk of Stunting Among Children Under Five Years of Age Nur Safitri Yunus; Sri Andriani Ibrahim; Rini Wahyuni Mohamad
Medical and Health Journal Vol 6 No 1 (2026): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.6.1.19314

Abstract

Stunting is a chronic nutritional issue among children under five, characterized by a height that is shorter than that of other children the same age. A low family socioeconomic status is a risk factor for stunting, as family finances are closely linked to the ability to secure adequate nutrition, nutritious food, and healthcare services for pregnant women and infants. This study aimed to determine the relationship between family socioeconomic status and the risk of stunting among children under five in Limboto District, Gorontalo Regency. A quantitative, observational-analytic study design with a cross-sectional approach was employed. The sample consisted of 97 children aged 0–24 months, selected using a purposive sampling technique. Data were collected using questionnaires assessing family socioeconomic status and stunting risk. Data analysis was performed using the Chi-square test, yielding a p-value of 0.001 (less than 0.05). These results indicate a significant relationship between family socioeconomic status and the risk of stunting among children under five in Limboto District, Gorontalo Regency. It is hoped that these findings will enhance parents' understanding of how family economic conditions influence stunting risk facilitated by health education at integrated health posts (Posyandu) thereby enabling them to take proactive measures to prevent stunting from an early stage.
Sleep Quality and Learning Concentration in School Age Children Ferdiyanto Hendra; Sri Andriani Ibrahim; Rini Wahyuni Mohamad
Medical and Health Journal Vol 6 No 1 (2026): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.6.1.19378

Abstract

Learning concentration is an individual’s ability to focus attention or thoughts during the learning process, leading to behavioral change. Good concentration allows students to understand the learning material more effectively and encourages greater enthusiasm and motivation during the teaching and learning process. This study aims to analyze the association between sleep quality and learning concentration among school-age children at SDN 16 Limboto Barat, Gorontalo Regency. This study employs a quasi-experimental design with a cross-sectional approach, using purposive sampling to obtain 83 respondents. Data were collected using a questionnaire and analyzed both manually and with SPSS version 21, using univariate and bivariate analyses. The results show that the majority of respondents have good sleep quality (70 respondents, 84.3%) and good learning concentration (63 respondents, 75.9%). The results also indicate that sleep quality is associated with learning concentration among school-age children at SDN 16 Limboto Barat, Gorontalo Regency with a value of 0.000 < α (0.05). These results are expected to serve as a foundation for efforts to improve the sleep quality of school-age children in order to support learning concentration.
Effectiveness of Bacteriocins in Yoghurt on Inhibiting the Growth of Escherichia Coli ATCC 25922 Rr. Berliana Dyah putri Anjani; IDSAP Peramiarti; Madya Ardi Wicaksono; Sutrisno Sutrisno
Medical and Health Journal Vol 6 No 1 (2026): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.6.1.19627

Abstract

Background: Escherichia coli is an important indicator of food contamination and a foodborne pathogen capable of causing serious infections. Naturally produced antimicrobial metabolites in yoghurt, including bacteriocins, have attracted increasing attention as potential alternatives to synthetic food preservatives. This study aimed to evaluate the antibacterial activity of yoghurt against E. coli ATCC 25922 at different concentrations. Methods: A true experimental study with a posttest-only control group design was conducted. Antibacterial activity was evaluated using the agar well diffusion method against E. coli ATCC 25922. Yoghurt was tested at concentrations ranging from 5% to 50% with 5% intervals. Data were analyzed using the Shapiro–Wilk normality test, followed by the Kruskal–Wallis test and Mann–Whitney post hoc analysis. Results: Chemical analysis estimated bacteriocin, lactic acid, and hydrogen peroxide levels in yoghurt at 148.00 mg/L, 35.12 mg/L, and 11.75 mg/L, respectively. No antibacterial activity was observed at yoghurt concentrations below 25%. Inhibition zones first appeared at a concentration of 25% and increased progressively with increasing yoghurt concentration, reaching the largest inhibition zone at 50%. Significant differences in inhibition zone diameters were observed among treatment groups (p < 0.05), indicating a concentration-dependent antibacterial effect. Conclusions: Yoghurt exhibited concentration-dependent antibacterial activity against E. coli ATCC 25922, with 25% representing the minimum concentration capable of inhibiting bacterial growth. The observed antibacterial activity is likely attributable to the synergistic effects of bacteriocins, lactic acid, and hydrogen peroxide produced during yoghurt fermentation. These findings support the potential application of yoghurt-derived antimicrobial metabolites as natural biopreservatives for improving food safety.
Qur’an Recitation Intensity and Anxiety Among Third-Trimester Pregnant Women: A Cross-Sectional Study Nurul Fatimah; Dahliah Dahliah; Ronaldo August Rambulangi; Anna Sari Dewi; Muhammad Wirasto Ismail
Medical and Health Journal Vol 6 No 1 (2026): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.6.1.19819

Abstract

Anxiety in women during the third trimester of pregnancy remains high and may have negative impacts on both maternal and fetal health. Data from the World Health Organization and studies in Indonesia indicate a high prevalence of anxiety as childbirth approaches. Non-pharmacological spiritual-based interventions, such as reading the Qur’an, are believed to promote relaxation and reduce anxiety; therefore, their relationship with anxiety levels in pregnant women needs to be investigated. This study aimed to determine the level of anxiety among third-trimester pregnant women at Wihdatul Ummah Clinic in Makassar, to assess the intensity of Qur’an reading, and to analyze the relationship between the intensity of Qur’an reading and anxiety levels. This study employed a quantitative observational analytic method with a cross-sectional design. The results showed that most third-trimester pregnant women were in the non-anxious category (69.4%), although 30.6% experienced anxiety ranging from mild to very severe. The majority of participants had a moderate intensity of Qur’an reading (66.7%), while 33.3% had a high intensity, and none had a low intensity. Statistical analysis showed no significant relationship between the intensity of Qur’an reading and anxiety levels among third-trimester pregnant women (p = 0.95). It can be concluded that there is no significant relationship between the intensity of Qur’an reading and anxiety levels among third-trimester pregnant women at Wihdatul Ummah Clinic, Makassar.
Education and Application of Diabetic Foot Exercises in Ilotidea Village, Tilango Sub-District, Gorontalo Regency Mohamad Nurhidayat Ento; Nasrun Pakaya; Rachmawaty D. Hunawa; Svetlanikova Svetlanikova; Novita Angraeni; Sri Wahyuni Kasim; Indrawati Mamu
Medical and Health Journal Vol 6 No 1 (2026): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.6.1.20115

Abstract

Diabetes Mellitus is a chronic disease characterized by elevated blood glucose levels and has the potential to cause various complications if not properly managed. Lack of patient knowledge about the disease and the importance of physical activity is one of the factors affecting the success of Diabetes Mellitus management. One of the non-pharmacological efforts that can be implemented is through health education and the application of diabetic foot exercises. The purpose of this activity was to improve patients’ knowledge about Diabetes Mellitus and to train patients’ ability to perform diabetic foot exercises independently. The method used was health education about Diabetes Mellitus and demonstration of diabetic foot exercises followed by direct practice by participants. The results show an improvement in patients’ understanding of Diabetes Mellitus as well as their ability to perform diabetic foot exercises. Most participants are able to perform the movements correctly and independently. The conclusion is that education on Diabetes Mellitus and the implementation of diabetic foot exercises are effective in improving patients’ knowledge and skills as an effort for independent disease management.

Page 16 of 19 | Total Record : 188

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