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Journal of Health Management and Pharmacy Exploration (JOHMPE)
Published by shm publisher
ISSN : 29854814     EISSN : 29855543     DOI : https://doi.org/10.52465/johmpe
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health Veterinary
Journal of Health Management and Pharmacy Exploration (JOHMPE) P-ISSN: 2985-4814 | e-ISSN: 2985-5543 is a journal that contains research material related to health management and pharmacy. Articles devoted to discussing any and all aspects of the most recent and noteworthy advancements in the fields of the development of health management science and pharmacy is possible to get the benefits of the application in life, especially from the perspective of the community, educational, and health institutions. The JOHMPE accepts manuscripts that are closely related to the health sector, including research articles, systematic reviews, and meta analyses. The Journal of Health Management and Pharmacy Exploration (JOHMPE) publishes contributions from a wide range of disciplines including: Health Policy Health Management Health Economics Health policy analysis Health policy ethics Politics of health Epidemiology Public health Phytochemistry social public policy Philosophy of health Clinical Pharmacy Community Pharmacy Pharmaceutics Pharmaceutical Chemistry Pharmacognosy
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 5 Documents
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Search results for , issue "Vol. 2 No. 1 (2024): February 2024" : 5 Documents clear
Potential of purple eggplant skin fraction (Solanum Melongena Var. Serpentinum L.) as an in vitro sunscreen Sari, Salza Laila; Wulandari, Wulandari; Mutiara, Erlita Verdia
Journal of Health Management and Pharmacy Exploration Vol. 2 No. 1 (2024): February 2024
Publisher : Surya Hijau Manfaat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52465/johmpe.v2i1.131

Abstract

Sunscreen is a product that is used as skin protection against sun exposure. The skin of purple eggplant is known to contain secondary metabolites which are used as sunscreens. This study aims to determine the activity of sunscreen fraction of the purple eggplant (Solanum melongena var. serpentinum L.) in vitro. Testing of sunscreen activity was carried out by calculating the value of SPF (Sun Protection Factor), %TE (Percent Transmission of Erythema) and %TP (Percent Transmission of Pigmentation) using the UV-Vis Spectrophotometry method. The purple eggplant skin fractionation method is by using LVC (Liquid Vacuum Chromatography). The results of the fractionation were identified using phytochemical screening and combined TLC. The fraction results were tested for SPF (Sun Protection Factor), %TE and %TP values. The results showed that the extract yield was 26.33%. The fractions used are fraction 9; 10; 11; and 12 which showed the same stain after being evaporated, which was a brownish yellow stain with a yield of 21,24%. The purple eggplant skin fraction (Solanum melongena var. serpentinum L.) has SPF, %TE and %TP values with optimal protection at a concentration of 400 ppm with each value obtained being 19; 1.35 and 9.79. The results of the statistical test of the purple eggplant skin fraction showed that the data were normally distributed but not homogeneous. The results of the homogeneity test for each concentration of results showed that the data were not significantly different.
Differences in drug availability levels before and during the covid19 pandemic in the pharmaceutical installation of NTB provincial hospital Wisnu, M. Ari; Herowati, Rina; Harsono, Samuel Budi
Journal of Health Management and Pharmacy Exploration Vol. 2 No. 1 (2024): February 2024
Publisher : Surya Hijau Manfaat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52465/johmpe.v2i1.192

Abstract

Health services are now increasingly needed during the COVID-19 pandemic which threatens public health. The need for public medicines that must be available such as flu, cough, vitamin c, antibiotics and antimalarials and antivirals for health services makes hospitals must try to fulfil and currently the COVID-19 pandemic situation is still continuing so hospitals must be ready to provide health services to patients.This study aims to determine the differences in drugs in the Pharmacy Installation of the NTB Provincial Hospital before the COVID-19 pandemic in 2019 and during the COVID-19 pandemic in 2020. This study is a descriptive-evaluative study with retrospective data collection in 2019 which represents the period before the COVID-19 pandemic and 2020 which represents the COVID-19 pandemic. The samples used in the study consisted of drug data from the Pharmacy Installation of the NTB Province Regional General Hospital (RSUD) and were analyzed using the Wilcoxon test. The results obtained are the level of drug availability in the pharmaceutical installation of the NTB Provincial Hospital obtained based on the results of observing data in 2019 and 2020, namely 19 and 37 months. There is a significant difference (Asymp. Sig (2-tailed) 0.000) the level of drug availability in the Pharmacy Installation of the NTB Provincial Hospital before and during the COVID-19 pandemic in 2020 with a difference of 18 months.
Phytochemical contents and diuretic activity of ethanolic extract of the red leaf lettuce (Lactuca Sativa l.) Lestari, Ratih Guswinda; Amin, Muhammad Saiful; Kusuma, Eka Wisnu
Journal of Health Management and Pharmacy Exploration Vol. 2 No. 1 (2024): February 2024
Publisher : Surya Hijau Manfaat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52465/johmpe.v2i1.201

Abstract

This study was conducted to evaluated of phytochemical content and diuretic activity of the red leaf lettuce. Red leaf lettuce were extracted by cold  maceration method using 70% ethanol for the 3 days and remaceration for 1 days. The phytocemical content  in ethanolic extract were evaluated by  qualitatif method. A total of 25 male rats were divided into 5 groups with CMC Na, a standard drug (furosemide 10 mg/kg), and three different doses (200, 300, and 400 mg/kg) of ethanol extract. Parameters used to determine diuresis activity include first urine latency, urine pH and cumulative urine volume. The ethanolic extract induced diuresis in a dose dependent manner as compared to the negative control. Extracts at doses of 200, 300, and 400 mg/kg produced significant diuresis effects (p<0.05) compared to negative controls with values of diuretic action 1.35; 1.43; and 1.53, respectively. In addition, there was a slightly change in the pH of urine samples of the extract-treated group compared with the negative control. Phytochemicals analysis revealed the presence of alkaloids, flavonoids, phenolics, and tannins.
Relationship between healthy house and smoking habits with afb (+) pulmonary tuberculosis cases at the singotrunan public health center, Banyuwangi district Fakhira, Amira Dhisa; Keman, Soedjajadi
Journal of Health Management and Pharmacy Exploration Vol. 2 No. 1 (2024): February 2024
Publisher : Surya Hijau Manfaat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52465/johmpe.v2i1.281

Abstract

Singotrunan Public Health Center has 65 cases of AFB (+) pulmonary TB, which means increased by 22.6% from the previous year. Healthy house and smoking habits are known to be some of the risk factors for pulmonary TB cases. This study aims to analyze the relationship between healthy house and smoking habits with AFB (+) Pulmonary Tuberculosis cases in the working area of the Singotrunan Public Health Center, Banyuwangi District. The method used is analytic research with a case-control type. This research was conducted on 28 samples, consist of 14 from the case group and 14 from the control group in the working area of the Singotrunan Health Center. Data were obtained from assessments using observation sheets and interviews using questionnaires. The data obtained were analyzed univariably using tabulation and bivariably using the Chi Square test using the Odds Ratio value to determine the dynamics of the independent and dependent variables. The results of the Chi Square test showed that there is a significant relationship between healthy houses (pvalue = 0.022) and smoking habits (pvalue = 0.002) with AFB pulmonary TB cases (+). The Odds Ratio value shows that unhealthy homes have a 6.6 times higher risk and smoking increases the risk 15 times higher for being diagnosed with AFB (+) Pulmonary TB. In conclusion, healthy homes and smoking habits have the potential to increase the risk of AFB (+) Pulmonary TB in the working area of the Singotrunan Public Health Center, Banyuwangi District.
Comparison of ethyl acetat fracination of ganitrie (Elaeocarpus sphearicus) seeds as anti bacterial of Staphylococcus aureus and determination of total flavonoid content Sari, Yunita Kurnia; Suharsanti, Ririn; Wulandari, Wulandari
Journal of Health Management and Pharmacy Exploration Vol. 2 No. 1 (2024): February 2024
Publisher : Surya Hijau Manfaat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52465/johmpe.v2i1.291

Abstract

Infectious disease is a disease coused by the presence pf pathogenic microbes. Stahpylococcus aureus is a gram positive aerobic bacterium that couses phyogenic infections on humans. Antibiotics are the best choise to treat an infections. The purpose of this study was to determine the antibacterial activity of ganitri seed (Elaeocarpus sphearicus) to determine the exstract ratio, the ethyl acetat fractination of ganitri seeds woth a concetration of 35% on the growth of staphylococcus aureus bacteria and to determine the total flavonoid content. Exctraction was carried out by maceration method for 3x24 hours with 96% ethanol as solvent. Exctraction fractination using 2 methods, the first method is using 30% ethanol, cloroform, and ethyl acetat as solvent. The second fractination method uses hot destiled water and ethyl acetat as solvents. The test result of total flavonoid content in ganitri (Elaeocarpus sphearicus) seeds in ethanol exstract were 38.009 mgEQ / g, fraction 1 of 99.512 mgEQ / g, fraction 2 of 68.235 mgEQ / g. From the result of the determinatoin of the ethyl acrtat fraction 1 had highest yield with an average value of 99,512 mgEQ/g. The antibacterial activity test was 35% in each sample ang using a positive control of ciprofloxcacin and a negative control of DMSO. Based on the result of the clear zone of the ethanol extract was 1.118 cm, the ethyl acetate 1 fraction was 1.170 cm, and the ethyl acetat 2 fraction was 0,956 cm.

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