cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Wulandari
Contact Email
wulandari@stifar.ac.id
Phone
+6289635924667
Journal Mail Official
johmpe@shmpublisher.com
Editorial Address
https://shmpublisher.com/index.php/johmpe/about/contact
Location
Kota semarang,
Jawa tengah
INDONESIA
Journal of Health Management and Pharmacy Exploration (JOHMPE)
Published by shm publisher
ISSN : 29854814     EISSN : 29855543     DOI : https://doi.org/10.52465/johmpe
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health Veterinary
Journal of Health Management and Pharmacy Exploration (JOHMPE) P-ISSN: 2985-4814 | e-ISSN: 2985-5543 is a journal that contains research material related to health management and pharmacy. Articles devoted to discussing any and all aspects of the most recent and noteworthy advancements in the fields of the development of health management science and pharmacy is possible to get the benefits of the application in life, especially from the perspective of the community, educational, and health institutions. The JOHMPE accepts manuscripts that are closely related to the health sector, including research articles, systematic reviews, and meta analyses. The Journal of Health Management and Pharmacy Exploration (JOHMPE) publishes contributions from a wide range of disciplines including: Health Policy Health Management Health Economics Health policy analysis Health policy ethics Politics of health Epidemiology Public health Phytochemistry social public policy Philosophy of health Clinical Pharmacy Community Pharmacy Pharmaceutics Pharmaceutical Chemistry Pharmacognosy
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 5 Documents
 1 
Search results for , issue "Vol. 3 No. 2 (2025): August 2025" : 5 Documents clear
Activity test cream anti aging extract ethanol 70% star fruits leaves (Averrhoa bilimbi l.) on skin new zealand rabbit backs exposed to UV-A light Puspitasari, Iliananda; Saraswati, Maulita; Sari, Gigih Kenanga
Journal of Health Management and Pharmacy Exploration Vol. 3 No. 2 (2025): August 2025
Publisher : Surya Hijau Manfaat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52465/johmpe.v3i2.542

Abstract

Skin is an organ that protects humans from external influences. Damage to the skin can interfere with human health and appearance. One of the most feared things is premature aging, the main cause of skin aging and malignant melanoma is the entry of ultraviolet (UV) rays from the sun. One of the plants, namely starfruit leaves, has antioxidant content that can change or reduce free radicals and also as an anti-free radical such as flavonoids, saponins, alkaloids, and tannins. Cream can be used by applying it to the skin of the face to prevent anti aging. Objective: To determine the activity of anti-aging cream of 70% ethanol extract of starfruit leaves (Averrhoa bilimbi L.) on the back skin of New Zealand rabbits exposed to UV-A light. Methodology: Extract starfruit leaves using the maceration method with 70% solvent and make a cream preparation to test anti-aging activity with concentrations of 3%, 5%, and 7%. Results: Formulation 3 with a concentration of 7 % of starfruit leaf extract cream can provide optimal effects as an anti-aging agent when exposed to UV-A rays, seen from the average value which is almost the same as the positive control.
Preliminary identification of N-Acetyltransferase 2 (NAT2) gene polymorphisms in the dayak population Dewi, Lutfiana Aswindra; Peranginangin, Jason Merari; Dewi, Lucia Vita Inandha
Journal of Health Management and Pharmacy Exploration Vol. 3 No. 2 (2025): August 2025
Publisher : Surya Hijau Manfaat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52465/johmpe.v3i2.612

Abstract

Polymorphism is a change or mutation in a gene that does not cause a change in the protein structure. The N-Acetyltransferase NAT enzyme is encoded by the N-Acetyltransferase 2 (NAT2) gene, the N-Acetyltransferase 2 (NAT2) gene, several variations of DNA known as single nucleotide polymorphisms (SNPs) that alter the genotype, haplotype, and phenotype. The NAcetyltransferase 2 (NAT2) genotype was classified into three phenotypes, namely fast acetylators, intermediate acetylators, and slow acetylators. The purpose of this study was to determine the type of polymorphism and the type of polymorphism of the NAT2 gene of the Dayak tribe. In this study, blood samples from the Dayak tribe were isolated from the Wizard Genomic DNA Purification kit and then identified Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP). With stages 1. Denaturation 2. Anneling and 3. Extension using NAT2 N4 and N5 primers then RFLP with restriction enzymes KpnI, TaqI and BamHI then electrophoresed with 2% agarose gel. The results of the initial identification of the N-Acetyltransferase 2 (NAT2) gene polymorphism in the Dayak tribe obtained 5 types of genotypes NAT2*4/*5B (20%), NAT2*4/*6A (33.3%), NAT2*4/*7B (20%), NAT2*5B/5B (13.3%) and NAT2*7B/7B (13.3%). From the phenotype of the Dayak tribe, there are two medium acetylators (73.3%) and slow acetylators (26.3%).
Management physiotherapy for cervical root syndrome with ultrasound, nerve mobilization and exercise: a case report Salsabila, Dika Tiara; Pristanto, Arif; Fauzan, Muhammad
Journal of Health Management and Pharmacy Exploration Vol. 3 No. 2 (2025): August 2025
Publisher : Surya Hijau Manfaat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52465/johmpe.v3i2.552

Abstract

Cervical Root Syndrome (CRS) is an abnormal condition caused by irritation or compensation of the cervical nerve roots, which can occur due to trauma. Arthritis, or compression of the intervertebral discs in the neck area. This research is to determine the benefits of providing ultrasound (US) modalities, nerve mobilization, isometric exercises, and stretching in CRS cases. The measurements used are pain measurement using the Numerical Rating Scale (NRS), Range of Motion (ROM) measurement using a goniometer, muscle strength measurement using Manual Muscle Testing (MMT), and functional activity measurement using the Neck Disability Index (NDI). The research was carried out directly on a patient with CRS condition by administering therapy in three meetings with physiotherapy intervention.  After 3 therapy meetings carried out by the physiotherapy program for Cervical Root Syndrome with physiotherapy modalities in the form of US, nerve mobilization, isometric exercises and stretching, significant changes were seen in reducing pain, increasing joint range of motion, muscle strength and functional ability.
Counselling on the correct use of antibiotics to prevent antibiotic resistance and the use of family medicinal plants (toga) for health Astuty, Meilinda Windy; Solehah, Santi; Ambarwati, Suci; Rahman, Zihni Mahira; Silpia, Rena; Ramdani, Qisti Cahya Putri; Ramdhani, Salma Fitria
Journal of Health Management and Pharmacy Exploration Vol. 3 No. 2 (2025): August 2025
Publisher : Surya Hijau Manfaat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52465/johmpe.v3i2.558

Abstract

A significant increase in the use of antibiotics in the community is often not matched by a proper understanding of their use, potentially leading to antibiotic resistance. This research aims to educate the community about the importance of proper antibiotic use and the utilization of Family Medicinal Plants (TOGA) as alternative medicine. Community service activities were carried out on November 24, 2024 in Salam Mulya Village, Pondok Salam District, Purwakarta Regency, in collaboration with Holistic Purwakarta Hospital. The methods used included education and discussion, with the distribution of brochures containing information on the use of antibiotics and TOGA. The results of the activity showed that the community showed high enthusiasm for the education provided, with 50 participants attending and actively participating in the discussion. The positive response from the community showed an increased understanding of the importance of the correct use of antibiotics and the utilization of herbal medicines. It is hoped that this activity can be continued and developed to increase public awareness about health.
Effects of Moringa Leaf Extract on a Mouse Model of Dementia on Spatial Memory, MDA Levels, and Hippocampal Pyramidal Cell Count (CA1 & CA3) Melati, Fitri; Purwidyaningrum, Ika; Harmastuti, Nuraini
Journal of Health Management and Pharmacy Exploration Vol. 3 No. 2 (2025): August 2025
Publisher : Surya Hijau Manfaat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52465/johmpe.v3i2.633

Abstract

Antioxidants are substances needed by the body to neutralize free radicals and prevent damage caused by free radicals. Moringa leaves contain flavanoids, alkaloids, saponins and tannins that are antioxidants because of their ability to capture free radicals. This study aims to determine the effect of moringa leaf fractions on spatial memory ability using the Radial Arm Maze method, a decrease in malondialdehyde levels and inhibition of damage to the number of hippocampal pyramidal cells in CA1 & CA3 areas. Moringa leaves were extracted using the maceration method with 70% ethanol solvent. Then the ethanol extract of Moringa leaves was fractionated using the liquid-liquid method with n-hexane, ethyl acetate and water as solvents. Next, the mice were subjected to induction treatment with lead acetate, then observed for 21 days with the Radial Arm Maze, then the mice underwent surgery and their brains were removed for MDA level testing and histopathological observation. Data were analyzed statistically using one-way ANOVA (p<0.05) followed by Tukey's test. Based on the results obtained, the ethyl acetate fraction, n-hexane fraction and water fraction can influence the improvement of spatial memory by reducing latency time and type B errors, reducing malondialdehyde levels with TBARS and inhibiting damage to CA1 and CA3 hippocampal pyramidal cells which are characterized by pknotic neuron nuclei (shriveled), dark, solid, and vacuolized.

Page 1 of 1 | Total Record : 5

 1 

Filter by Year

2025 2025


Reset
Filter By Issues
All Issue Vol. 4 No. 1 (2026): February 2026 Vol. 3 No. 2 (2025): August 2025 Vol. 3 No. 1 (2025): February 2025 Vol. 2 No. 2 (2024): August 2024 Vol. 2 No. 1 (2024): February 2024 Vol. 1 No. 2 (2023): August 2023 Vol. 1 No. 1 (2023): February 2023