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Eka Nurul Qomaliyah
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BIOCITY: Journal of Pharmacy Bioscience and Clinical Community
Published by Universitas Bumigora
ISSN : -     EISSN : 29640733     DOI : https://doi.org/10.30812/biocity
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
BIOCITY: Journal of Pharmacy Bioscience and Clinical Community aim to promote innovative research, theory and practical application that can solve pharmaceutical and clinical science challenges both laboratory and community based. Biocity Journal mainly focuses on a current topic in Pharmaceutical Sciences are also considered for publication by the Journal. Discussions on a topic in Pharmaceutical Sciences, detailed scopes of articles accepted for submission to Biocity are: Pharmacy Bioscience, Pharmaceutical sciences, Technology of Herbal Formulations, Extract and Herbal Standardizations, Pharmacological activity determination on natural sources, Health and Environmental issues, Pharmacy Clinical Community.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 60 Documents
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Analisis Profil Pemberian Obat Golongan Proton Pump Inhibitor (PPI) pada Penanganan Gastritis Amalia, Aini; Indriani, Nurul; Kresnapati, I Nyoman Bagus Aji
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 3 No 2 (2025): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v3i2.5339

Abstract

Gastritis is an inflammation of the gastric mucosa that is commonly found in healthcare facilities, including Tripat Regional General Hospital. One of the main therapies for gastritis is the use of Proton Pump Inhibitor (PPI) medications, which work by reducing gastric acid secretion. This study aims to understand the profile of PPI administration in gastritis patients at Tripat Regional General Hospital in 2023. This study uses a retrospective descriptive approach, collecting data from the medical records of outpatient and inpatient patients in 2023. The results show that the number of gastritis cases reached 574 patients. The most commonly used PPI medication is omeprazole (38.4%), with the most frequently prescribed dosage being 20 mg (52.3%), and the most common administration frequency is once a day (93.0%). The conclusion of this study indicates that the use of PPI in gastritis patients at Tripat Regional General Hospital is mostly in accordance with guidelines
Analisis Tingkat Kepatuhan Minum Obat terhadap Kejadian Kekambuhan pada Pasien Gastroesophageal Reflux Disease (GERD) Rasyid, M. Gazali Abdul; Indriani, Nurul; Kresnapati, I Nyoman Bagus Aji
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 3 No 2 (2025): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v3i2.5367

Abstract

:  Gastroesophageal Reflux Disease (GERD) is a digestive tract disorder with a rising prevalence both globally and in Indonesia. Recurrence among GERD patients is often linked to medication adherence. This study aims to analyze the relationship between medication adherence and recurrence in GERD patients at RSUD Tanjung in 2024. A qualitative method was used, with data collected from medical records of patients undergoing regular treatment. A total of 84 patients were selected using Slovin's formula from a population of 538 patients. Data were analyzed descriptively and followed by Chi-Square, Homogeneity, and ANOVA tests. The results showed that the recurrence rate among GERD patients was 66%, while the medication adherence rate was only 34%. The Chi-Square test showed no significant relationship between gender and visit frequency. The Homogeneity test indicated that the data variances among groups were homogeneous, and the ANOVA test showed a significant difference based on visit frequency. The study concludes that medication adherence among GERD patients at RSUD Tanjung remains low, contributing to a high recurrence rate. Educational and interventional efforts are needed to improve patient adherence to therapy in order to reduce GERD recurrence rates.
Analisis Kejadian Dispepsia terhadap Faktor Pemicunya Saputri, Syarifa Anita; Indriani, Nurul; Kresnapati, I Nyoman Bagus Aji
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 3 No 2 (2025): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v3i2.5383

Abstract

Analysis of Dyspepsia Incidence Against Trigger Factors in Patients at the Narmada  Health Center. Dyspepsia is a common condition characterized by discomfort or pain in the upper abdomen, and can affect a person's quality of life and have a negative impact on the sufferer's productivity. The purpose of this study was to analyze the incidence of dyspepsia against its triggering factors in Narmada Health Center. This study used a quantitative method with a cross-sectional research design, with a questionnaire instrument that was valid (0.612 - 0.951) and reliable (> 0.90). Results The prevalence of dyspepsia in this study was 164 people based on data from the Narmada Health Center. The frequency of knowledge levels, consuming frogs, exercising on an empty stomach, smoking habits, and the begibung tradition did not show a significant relationship with the incidence of dyspepsia in the community (p-value> 0.05). Meanwhile, the incidence of dyspepsia has a significant relationship with the frequency of consumption of spicy foods, sour foods, fatty foods, raw foods, consuming coffee with a value (p-value <0.05). The conclusion of this study is that the frequency of consumption of spicy foods, sour foods, fatty foods, raw foods, consuming caffeine and drugs are risk factors for the incidence of dyspepsia in the patients at Narmada Health centers
Pola Penggunaan dan Rasionalitas Terapi Obat pada Pasien Gagal Jantung Kongestif Angkasa, Adelya Putri; Wulandari, Prihastini Setyo; Listina, Osie
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 3 No 2 (2025): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v3i2.5470

Abstract

Congestive Heart Failure (CHF) is one of the cardiovascular diseases with high prevalence and significant morbidity and mortality rates, including in RSUD dr. Soeselo Tegal Regency. Rational pharmacotherapy management is crucial to reduce hospitalization rates and improve patient quality of life. This study aims to evaluate the use of drugs in hospitalized CHF patients based on the parameters of correct diagnosis, correct indication, correct drug, and correct dose. The design of this study was descriptive observational with a retrospective approach, using medical record data of CHF patients treated at RSUD Dr. Soeselo Tegal Regency during the period July-December 2023. The samples analyzed were 79 patients. The results showed that the most widely used drug classes were loop diuretics (furosemide), beta-blockers (bisoprolol, carvedilol), aldosterone antagonists (spironolactone), ARBs (candesartan), and ACE-I (ramipril, captopril). The majority of patients received therapy at doses appropriate for standard CHF therapy and the longest inpatient stay was 7 days. The evaluation showed that all patients had received therapy that met the four indicators of rational use of drugs (100% correct diagnosis, 100% correct indication, 100% correct drug, and 100% correct dose). The conclusion of this study indicates that the use of CHF drugs in hospitalized patients at RSUD Dr. Soeselo Tegal Regency has been carried out rationally and in accordance with national therapeutic guidelines
Pengukuran Quality of Life Menggunakan Kuesioner SF-36 pada Pasien Hipertensi Fahamsya, Arifina; Listina, Osie; Maulinda, Yanda Rizqi
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 3 No 2 (2025): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v3i2.5485

Abstract

A rise in arterial blood pressure of 140/90 mmHg or higher is referred to as hypertension. One statistic used to assess how well health services are being prevented and treated is quality of life. Determining the characteristics of hypertension patients at the Talang Community Health Center, assessing their quality of life there, and identifying the factors affecting their quality of life were the goals of this study. This kind of study was quantitative, descriptive, and employed a cross-sectional technique. There were eighty responders in the study sample. Non-probability sampling using a successive sampling method was the sampling strategy used. The findings of the bivariate analysis indicated that the physical component summary was significantly correlated with age, gender, and duration of suffering, whereas the mental component summary was correlated with education and duration of suffering (p <0.05). The multivariate analysis's findings indicated that the physical component summary was influenced by age, gender, and length of suffering. On the other hand, the mental component summary was influenced by the length of suffering. Neither the mental nor the physical components were impacted by education. With physical component summary scores of 42.23 and mental component summary scores of 43.10, respondents with hypertension at the Talang Health Center experienced a low quality of life.
Tingkat Pengetahuan terkait Efek Samping Dextromethorphan Hydrobromide pada Komunitas Cosplay: Studi Deskriptif Lalu Dea Nune Idham; Novitarini; Mia Ariasti
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 4 No 2 (2026): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Universitas Bumigora

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v4i2.5569

Abstract

Dextromethorphan Hydrobromide (DMP HBr) is one of the active ingredients in cough medicine, acting as an antitussive, and is widely used by the public because it is easy to obtain. Inappropriate use of the dosage can cause various side effects, such as drowsiness, dizziness, hallucinations, and the risk of abuse. This study aims to determine the level of knowledge among cosplay community members in Mataram City regarding the side effects and risks of abusing DMP HBr in cough medicine. The study used a qualitative, cross-sectional, Post-TestOnly design. Data were collected through questionnaires and interviews with 100 respondents from three cosplay communities in Mataram City, namely Banzai Mataram Japan Community, Wibufest Mataram, and Anime no Sekai Mataram. The results showed that 45% of respondents hadknowledge at the sufficient level, 23% at the good level, and 32% at the poor level. Therefore, it can be concluded that cosplay community members in Mataram City have a sufficient level of knowledge regarding the side effects and risks of abuse of DMP HBr, but further education is still needed regarding the rational and safe use of drugs.
Uji Validitas dan Reabilitas Kuesioner Naranjo untuk Mengukur Adverse Drug Reactions (ADRs)Pasien Aterosklerosis I Nengah Satria Wirananda; Fitri Apriliany; Novitarini
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 4 No 2 (2026): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Universitas Bumigora

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v4i2.5842

Abstract

Patients with atherosclerosis receive concomitant cardiovascular medications, and the use of multiple medications can increase the risk of adverse drug reactions (ADRs). ADRs assessment is crucial to differentiate drug side effects from other conditions, like comorbidities, drug interactions, or environmental factors. ADRs are generally measured using the Naranjo algorithm questionnaire. The purpose of this study is to determine the validity and reliability of the Naranjo questionnaire for measuring ADRs in patients with atherosclerosis. This study used a non-experimental, descriptive-analytical design with a cross-sectional approach and prospective observation. The subjects in this study were 30 patients with atherosclerosis, and data were collected using the Naranjo algorithm questionnaire. The results showed that the Naranjo algorithm questionnaire was valid, as the content validity test yielded a Pearson Correlation coefficient of >0.361. This instrument was deemed reliable because its Cronbach’s alpha was>0.60. Therefore, the Indonesian version of the Naranjo algorithm questionnaire is valid and reliable, and can be used to measure adverse drug reactions in patients with atherosclerosis.
Analisis Kadar Vitamin C pada Selai Buah Naga Merah (Hylocereus polyrhizus) dengan Penambahan Ekstrak Daun Kelor (Moringa oleifera) sebagai Sumber Antioksidan Rida Astria; Salsabila Ardelia; Saepudin Rahmatullah
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 4 No 2 (2026): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Universitas Bumigora

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v4i2.6052

Abstract

Vitamin C is a water-soluble vitamin essential for the body and is known as a powerful antioxidant capable of reducing free radicals and protecting cells from oxidative damage. However, vitamin C is very easily degraded, so its levels in food often decrease during processing and storage. This study aims to analyze vitamin C levels in red dragon fruit (Hylocereus polyrhizus) jam, with and without the addition of moringa leaf extract (Moringa oleifera), using the iodometric titration method. The results showed that the vitamin C level in the standard jam was 38.04 mg/100 g, while the jam with moringa leaf extract decreased to 20.43 mg/100 g. This decrease was influenced by the degradation of ascorbic acid due to heat, oxidation, the presence of bioactive compounds and metal ions in the moringa extract, and possible matrix interference in the titration analysis. The complexity of the jam’s color and viscosity can also affect the accuracy of the titration endpoint determination. Thus, the addition of moringa leaf extract did not increase vitamin C retention, and a more selective analytical method is recommended for further research.
Uji Aktivitas Antibakteri Ekstrak Daun Tempuyung (Sonchus arvensis L.) terhadap Pseudomonas aeruginosa dan Bacillus cereus Amrina Rosada; Baiq Yulia Hasni Pratiwi; Lalu Busyairi Muhsin
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 4 No 2 (2026): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Universitas Bumigora

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v4i2.6256

Abstract

Pseudomonas aeruginosa and Bacillus cereus are two dangerous pathogenic bacteria that are often resistant to antibiotics. This study aims to determine the antibacterial activity of the ethanol extract of tempuyung leaves (Sonchus arvensis L.) against Pseudomonas aeruginosa and Bacillus cereus bacteria. The antibacterial activity test used the well-diffusion method at extract concentrations of 10%, 25%, 50%, and 75%, with ciprofloxacin as the positive control and 10% DMSO as the negative control. The results of the antibacterial test showed that the extract did not produce an inhibition zone at any concentration against either bacterium, whereas the positive control showed a strong inhibition zone. Thus, the ethanol extract of tempuyung leaves was ineffective against Pseudomonas aeruginosa and Bacillus cereus under the tested conditions, with inhibition zones not exceeding the strong category. Further research is recommended to identify the active compounds using GC-MS and to test them on other types of bacteria.
Perbandingan Eksperimental Parafin dan Palm Wax terhadap Kualitas Lilin Aromaterapi Melati Aniza Istichomah; Febiana Rustiana Dewi; Eka Nurul Qomaliyah; Fika Erdina Azzahro; Intan Nadia; Muhammad Huda Najaya
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 4 No 2 (2026): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Universitas Bumigora

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v4i2.6267

Abstract

This study aims to compare the physical and organoleptic characteristics of aromatherapy candles made from paraffin and palm wax, both infused with jasmine essential oil (Jasminum sambac). Using a laboratory experimental approach, two formulas were prepared: Formula 1 (paraffin) and Formula 2 (palm wax). Each formulation was mixed with cooking oil in a 1:1 ratio and supplemented with 25 mL of jasmine essential oil. Quality was assessed by 11 panelists through organoleptic tests (color, shape, texture, and aroma) and physical tests (melting point and burning time) in accordance with SNI 0386-1989-A/SII 0348-1980 standards. Results showed that palm wax-based candles had a higher melting point (57oC), longer burning time (±270 minutes), and were preferred by panelists, especially for aroma and texture, compared to paraffin wax candles (melting point 54oC, burning time ±180 minutes). In summary, palm wax is better suited for aromatherapy candles due to its superior physical properties, sensory qualities, and extended burn time.

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