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Eka Nurul Qomaliyah
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INDONESIA
BIOCITY: Journal of Pharmacy Bioscience and Clinical Community
Published by Universitas Bumigora
ISSN : -     EISSN : 29640733     DOI : https://doi.org/10.30812/biocity
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
BIOCITY: Journal of Pharmacy Bioscience and Clinical Community aim to promote innovative research, theory and practical application that can solve pharmaceutical and clinical science challenges both laboratory and community based. Biocity Journal mainly focuses on a current topic in Pharmaceutical Sciences are also considered for publication by the Journal. Discussions on a topic in Pharmaceutical Sciences, detailed scopes of articles accepted for submission to Biocity are: Pharmacy Bioscience, Pharmaceutical sciences, Technology of Herbal Formulations, Extract and Herbal Standardizations, Pharmacological activity determination on natural sources, Health and Environmental issues, Pharmacy Clinical Community.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 45 Documents
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Analysis of Physicochemical Properties of Bidara Leaves (Ziziphus spina-christi L.) Dried using Tray Dryer at Different Temperatures Al Fira Safitri; Devi Tanggasari
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 2 No 1 (2023): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v2i1.3160

Abstract

The Bidara plant (Ziziphus spina-christi L) is a kind of small evergreen tree. Bidara plants are easy to find in Indonesia, especially in Sumbawa Regency, West Nusa Tenggara. Bidara leaves have many pharmacological potentials, including antioxidants, antibacterial, antiparasitic and anti-cancer. Bidara leaves can be developed into efficacious herbal products. The drying process greatly affects the quality of bidara leaves. Temperature in the drying process is an important factor because it can affect the content of bioactive compounds in bidara leaves. The purpose of this study was to determine the effect of drying temperature on physical and chemical properties. The dryer used in this drying is a tray dryer. The experimental design used in this study was a completely randomized design (CRD) with one factor. The temperatures used were 45, 50 and 55°C with a drying time of 3 hours. The results showed that the drying temperature affected the physical and chemical properties of bidara leaves. The best treatment for drying bidara leaves is drying at 55°C for a weight loss of 90.8%; water content 33.8% and temperature 45℃ for protein content 14.23%; Flavonoid content 11.71%.
Pengaruh Perbedaan Suhu Pengeringan Menggunakan Tray Dryer terhadap Karakteristik Fisik dan Kimia Cabai Rawit (Capsicum frutescens L.) Susilawati Susilawati; Devi Tanggasari
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 2 No 1 (2023): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v2i1.3161

Abstract

Cayenne pepper (Capsicum frutescens L.) is a potential vegetable crop that has high economic value and has the potential to continue to be developed, but cayenne pepper is a type of fruit that is easily damaged, therefore proper post-harvest handling is needed, one of which is drying. The purpose of this study was to determine the effect of different drying temperatures on physical analysis (weight loss) and chemical analysis (moisture content, vitamin C and capsaicin content). The dryer used in this study was a tray dryer. The experimental design used was a one-factor Completely Randomized Design (CRD) with 3 treatments. The temperatures used in this study were 40, 50, and 55°C. Based on the results of the study, it was found that the best decrease in weight loss in drying cayenne pepper was at 55°C with a decrease in weight loss of 62.67%. The best decrease in water content for drying cayenne pepper was at 55°C with a total moisture content of 50.3%. The best vitamin C content was found at 45°C, which was 0.65%, and the best capsaicin content for drying cayenne pepper was found at 45°C, which was 244.4702 ppm with an SHU level of 730.776.
Analisis Adverse Drug Reactions (ADRs) Penggunaan Antibiotik Terhadap Penyakit Community Acquired Pneumonia (CAP) Pada Balita Di RSUD Kota Mataram Fanny Dwi Febriyana; Fitry Apriliany; Muh. Isnaini Zuhri
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 2 No 1 (2023): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v2i1.3229

Abstract

Pneumonia is an infection that causes inflammation of the lung tissue so that the lung sacs are filled with infectious agents and are the main cause of infant mortality in the world. The initial therapy for pneumonia is the use of antibiotics. Irrational use of antibiotics can lead to ADRs. Adverse Drug Reactions (ADRs) often cause obstacles in the implementation of treatment. The purpose of this study was to see how ADRs influence the use of antibiotics on the clinical outcomes of pneumonia patients. The method analytic observational study using a cross-sectional design which is carried out prospectively, by collecting data on inpatients. Data were obtained from interviews with patients and/or patient families using the Naranjo questionnaire, as well as searches of patient medical records during the period January - March 2023. Analysis of ADRs on the use of antibiotics on outcomes was analyzed by the Likelihood ratio. This study was dominated by patients aged <2 years (61.5%) with improved outcomes (97.15%). The results obtained showed that there was no significant relationship between ADRs using antibiotics and patient outcomes with a p>0.05 (p=0.798). The conclusion of this study is that there is no effect of ADRs using antibiotics on patient outcomes.
Analisis Efek Samping Penggunaan Vaksin COVID-19 (Booster) Moderna COVID19 Vaccine® Pada Tenaga Kesehatan Di Puskesmas Santong, Kecamatan Kayangan, Kabupaten Lombok Utara Tahun 2023 Handini Mulianti; Muhammad Isnaini Zuhri; Widani Darma Isasih
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 2 No 1 (2023): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v2i1.3284

Abstract

The Coronavirus Disease 2019 (COVID-19) is an infectious condition caused by the SARS-CoV-2 virus. This virus has undergone mutations, leading to new variants that have contributed to the increase in COVID-19 cases. Governments have initiated vaccination efforts as part of their strategies to curb the spread, particularly among healthcare workers. However, concerns have arisen regarding the occurrence of post-vaccination side effects. The objective of this study is to identify and categorize the side effects that arise after administering the COVID-19 (booster) vaccine, specifically the Moderna COVID-19 Vaccine®. The study employs a cross-sectional approach, collecting data through interviews and questionnaire completion among medical staff at Puskesmas Santong in April 2023. The study's findings reveal that out of 69 respondents, 94.2% experienced side effects following vaccination, while 5.8% did not encounter any. The majority of these side effects fall into the "probable" category (69.6%) according to the Naranjo Scale Algorithm. Common systemic side effects include fever (60.9%), dizziness (43.5%), fatigue (33.3%), muscle aches (31.9%), joint pain (13%), chills (11.6%), headache (10.1%), nausea (4.3%), runny nose (1.4%), and sneezing (1.4%). Local side effects, such as injection site pain, were reported by 34.8% of the respondents. The majority of these side effects persisted for 2 days (42%).
The Effect of Variations in HPMC and Carbopol Bases on The Physical Stability of Okra (Abelmoschus esculentus L.) Fruit Gel Formulations Irman Idrus; Rahayu Apriyanti; Syaiful Katadi; Nurfitriyana Rahmat; Sabda Wahab; Dzul Asfi
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 2 No 1 (2023): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v2i1.3399

Abstract

Okra fruit (Abelmoschus esculentus L.) is a vegetable that is often used as medicine. Okra fruit contains flavonoids which are antioxidants. Gel formulation with a concentration of 5%, and various combinations of HPMC and carbopol bases. This research aims to determine the physical stability of gel preparations and the effect of variations in the concentration of gelling ingredients in the preparations. The gel formulation consists of 4 formulas, namely F0, F1, F2, and F3. Physical stability tests include organoleptic tests (odor, color and texture), homogeneity, pH, spreadability, stickiness, viscosity and synergy. Tests were carried out for 14 days of storage, namely on days 1, 3, 5, 7, and 14 at room temperature (25℃). The observation results showed that in the organoleptic test there was no change in color, odor and texture in the gel preparation during 14 days of storage. The four gel formulas are homogeneous and there is no synergy. Variations in the combination of HPMC and carbopol bases affect the physical properties of the gel, including pH, viscosity, spreadability and adhesion. HPMC and Carbopol affect the pH of the preparation, the higher the Carbopol content and the lower the HPMC content, the more acidic it is. Carbopol and HPMC affect the values of spreadability, viscosity and adhesion because the higher the concentration of carbopol and HPMC produces a thick gel preparation so that the spreadability decreases, viscosity increases and adhesion also increases.
Hubungan Kejadian Gastritis dengan Riwayat Penggunaan Obat Anti Inflamasi Non Steroid (OAINS) pada Pasien yang Melakukan Pemeriksaan Endoskopi Nirmala Putri, Kintan Nandini; Apriliany, Fitri; Ramdhany, Muh. Wisda Praja
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 2 No 2 (2024): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v2i2.3319

Abstract

Gastritis is inflammation of the gastric mucosa, one of which is caused by the use of non-steroidal anti-inflammatory drugs (NSAIDs). It is very common that NSAIDs are used to treat pain, fever, and inflammatory processes. This study aims to examine the relationship between the incidence of gastritis and a history of NSAIDs use. The research method use in this study is a retrospective cohort design of which the data is collected through interview of patients and their families. The patients medical records at the Mataram City Regional Hospital was also collected. Testing was carried out using the Pearson Correlation test. The result shows that gastritis patients were dominated by people aged 36-55 years (46.43%) and 49 of them were female (58.33%). The Pearson Correlation test shows no significant relationship between the incidence of gastritis and a history of NSAID use, with a p-value> 0.05 and an r-value < 1. This indicates a weak relationship between gastritis and the use of NSAIDs. Therefore, the history of NSAIDs use is insignificant as the main reason for gastritis. Gastritis can also be caused by other factors such as age, lifestyle, and stress levels.
Pengaruh Reminding melalui Whatsapp Terhadap Kepatuhan Minum Obat pada Pasien Tuberkulosis Paru Saputra, Yovi Agus; Apriliany, Fitri; Ramdhany, Muh. Wisda Praja
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 2 No 2 (2024): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v2i2.3320

Abstract

Pulmonary tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. M. tuberculosis enters the body through inhaled air and spreads in the lungs. In 2021, Mataram City detected a total of 739 tuberculosis cases. Many tuberculosis patients still exhibit low adherence to taking their medication. This research investigates the influence of WhatsApp reminders on medication adherence in pulmonary tuberculosis patients. This is an analytical observational study with a quasi-experimental design that employs a prospective pre-test and post-test approach. The data for this study was collected from outpatient patients at RSUD Kota Mataram. The result indicates a significant improvement in medication adherence among pulmonary tuberculosis patients, with a significant value of the Wilcoxon test (p = 0.000, <0.05). The conclusion drawn from this study is that reminders through WhatsApp influence medication adherence in pulmonary tuberculosis patients at RSUD Kota Mataram.
Analisis Penggunaan Antibiotik Profilaksis pada Pasien Bedah Sesar (Sectio Caesarea) Monica, Anggi; Ramdhany, Muh. Wisda Praja; Putra, Made Sandhi Pratama
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 2 No 2 (2024): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v2i2.3326

Abstract

Cesarean section (C-section) is a delivery method involving surgical incisions on the abdomen and uterus. C-section carries the risk of postoperative complications such as surgical site infection (SSI). Hence, there is a need for prophylactic antibiotic administration. Prophylactic antibiotics are used to prevent infection complications resulting from surgery and are administered before, during, and after the operation. The selection of antibiotics is crucial because inappropriate antibiotic use can lead to resistance. This research aims to analyze the usage profile and evaluate the rationality of prophylactic antibiotics in C-section procedures at Wira Bhakti Hospital. This study is a non-experimental descriptive research in which retrospective data collection was conducted in the form of medical records of C-section patients. Also, the rationality assessment was performed using the Gyssens method. The research findings show that the most used antibiotics are ceftriaxone (70.6%), cefotaxime (25%), and cefoperazone (4.4%). Meanwhile, the rationality assessment using Gyssens' method shows that all prophylactic antibiotic use falls under the categories of IVA (more effective alternative) and IVD (narrower spectrum alternative).
Hubungan Karakteristik dengan Tingkat Pengetahuan Keluarga Pasien terkait Beyond Use Date (BUD) Obat Sirup Kering Atmi, Nur Azizah; Rhamdany, Muh. Wisda Praja; Putra, Made Sandi Pratama
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 2 No 2 (2024): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v2i2.3327

Abstract

Most households in Indonesia keep a stock of medicines, but the public's knowledge of medicine storage remains low. The term BUD in drug storage is very important to know because BUD is related to the stability and quality of drugs. If drug storage is not appropriate, it can result in irrational drug use. This research aims to determine the relationship between characteristics and the patient's family's level of knowledge about the BUD of dry syrup at the Mataram City Regional Hospital. This research is a type of analytical observational research with a cross-sectional design that uses a valid (0.411-0.780) and a reliable (>0.06) questionnaire instrument. The respondents involved in this study were 60 guardians of patients who received dry syrup medication. The level of knowledge of the patient's guardians regarding BUD for dry syrup is dominated by the excellent category. The highest results of filling out the questionnaire were 56 people, with a correct answer of 76% - 100%. The bivariate analysis using chi-square shows that the characteristic that is related to the level of knowledge about BUD dry syrup medicine is the level of education (p=0.007). The domain of information sources supporting BUD for dry syrup medicine also relates to the respondents' knowledge level of BUD for dry syrup (p=0.000). This study concludes that only the characteristics of the level of education have a relationship with the level of knowledge of the patient's guardians regarding BUD dry syrup.
Profil Fitokimia dan Aktivitas Antibakteri Bunga Kekara Laut (Canavalia rosea) Menggunakan Metode Difusi Cakram Idrus, Irman; Nasrun, Efa Kelya; Ramandha, Muhammad Eka Putra
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 2 No 2 (2024): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v2i2.3988

Abstract

Bacterial infection is one of the leading causes of chronic diseases and ongoing risks of mortality that continuously threaten public health globally. Improper use of antibiotics can lead to pathogenic bacteria developing resistance to antibiotics and cause dangerous side effects. Therefore, searching for alternative antibiotic sources derived from natural materials is essential. One type of plant that has the potential as an antibacterial agent is Canavalia rosea. This research aims to qualitatively assess the phytochemical content using tube methods and evaluate the antibacterial activity of the ethyl acetate fraction of Canavalia rosea extract using the disc diffusion method. Canavalia rosea leaves were extracted using a maceration method using 96% ethanol, and fractionation was done using ethyl acetate. Phytochemical analysis showed alkaloid, saponin, flavonoid, polyphenol, and tannin compounds in the Canavalia rosea flower extract. The antibacterial activity of the ethyl acetate fraction of the extract showed a significant inhibition zone against the growth of Staphylococcus aureus bacteria. At a concentration of 9 mg/mL, the inhibition zone reached 20.31 ± 0.27 mm, falling into the moderate to strong category. While at a concentration of 1.5 mg/mL, the inhibition zone reached 5.13 ± 0.32 mm, indicating lower inhibitory effects. Statistical analysis showed that the ethyl acetate fraction of Canavalia rosea extract has significant antibacterial activity, with each concentration having different effects in inhibiting the growth of S. aureus.

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