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All Journal Current Biochemistry Folia Medica Indonesiana Journal of Natural Sciences and Mathematics Research Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Biotek Jurnal Keperawatan Terpadu (Integrated Nursing Journal) Jurnal Ners Jurnal Ilmiah Pharmacy Jurnal Pijar MIPA Jurnal Medical Laboratory Jurnal Ilmiah Pengabdian dan Inovasi Jurnal Multidisiplin Sahombu PCJN Pharmaceutical and Clinical Journal of Nusantara Darma Diksani: Jurnal Pengabdian Ilmu Pendidikan, Sosial, dan Humaniora BIOCITY: Journal of Pharmacy Bioscience and Clinical Community Alamtana Indonesian Journal of Health Research Innovation

Kresnapati, I Nyoman Bagus Aji

Universitas Bumigora

Author-ID : 5804655

Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Ethanol Extract of Marigold Flower (Tagetes Erecta L.) Decreases The Total Cholesterol, Low Density Lypoprotein (LDL), Malondialdehyde (MDA), and Apoliprotein B (APOB) on Hyperlipidemia Rat Models I Nyoman Bagus Aji Kresnapati; Siti Khaerunnisa; Indri Safitri
Folia Medica Indonesiana Vol. 57 No. 3 (2021): September
Publisher : Universitas Airlangga

This study aimed to determine the effect of ethanol extract of gemitir flower (Tagetes erecta L.) on total cholesterol levels, Low-Density Lipoprotein C (LDL), Malondialdehyde (MDA), Apolipoprotein B (ApoB). Forty-eight Rattus norvegicus were randomly divided into 6 groups, groups were given standard feed (K-) and 5 groups of hyperlipidemia models (K +, P1, P2, P3, P4) were given High Fat Diet (HFD) for 35 days. On the 36th day, the total cholesterol levels were checked through the tail of Rattus norvegicus, and from day 37 to day 50 were given a normal diet (K-), HFD (K +), simvastatin 10 mg/kgBW (P1), ethanol extract of gemitir flowers (Tagetes erecta L.) 200 (P2), 400 BW (P3), and 800 mg/kgBW (P4). On day 51, the total cholesterol, LDL-C, MDA, and ApoB blood serum levels were checked. The results showed total cholesterol, Low-Density Lipoprotein (LDL), Malondialdehyde (MDA), and Apolipoprotein B (ApoB) given ethanol extract of gemitir flowers 200 and 400 mg/kgBW (P2) had a significant reduction (P < 0.05). Giving ethanol extract of gemitir flower (Tagetes erecta L.) could reduce levels of total cholesterol, LDL, MDA, and Apo B.

UJI EVALUASI FITOKIMIA TUMBUHAN HERBAL BERDASARKAN INFORMASI EMPIRIS PADA MASYARAKAT LOMBOK Nurul Indriani; MUHAMMAD EKA PUTRA RAMANDHA; I Nyoman Bagus Aji Kresnapati
Jurnal Medical Laboratory Vol. 2 No. 1 (2023): Januari: Jurnal MedLab
Publisher : Sekolah Tinggi Ilmu Kesehatan Kesetiakawanan Sosial Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/medlab.v2i1.131

Tujuan dari penelitian ini adalah untuk mengetahui potensi tumbuhan khas sasak dapat dijadikan bahan pengobatan atau obat alternatif oleh masyarakat. Uji yang dilakukan yaitu uji kulaitatif yaitu skrining fitokimia. Skrining dilakukan untuk mengetahui kandungan, alkaloid, flavonoid, terpenoid, tanin dan saponin. Penelitian ini merupakan penelitian dasar atau penelitian permulaan untuk menseleksi kandungan-kandungan obat dalam tumbuhan khas sasak. Preparasi sampel dilakukan pengeringan untuk mengurangi kadar air, dan masing-masing tumbuhan obat dilakukan maserasi dengan pelarut metanol 96% selama 2 x 24 jam. Ekstrak kental dilakukan pengujian menggunakan reagen menghasilkan warna tertentu. Hasil penelitian yaitu seluruh tumbuhan obat yang diuji berpotensi dijadikan obat dan dapat digunakan sebagai saran pengobatan oleh masyarakat.

Sosialisasi Meningkatkan Kesadaran Pentingnya Menabung Sejak Dini di TK Yarsi Mataram Puspita Ayu, Baiq Dinda; Aryani , R . Ayu Ida; I Nyoman Bagus Aji Kresna; Ana Rahmatyar; Muhammad Haris Nasri
Jurnal Ilmiah Pengabdian dan Inovasi Vol. 1 No. 2 (2022): Jurnal Ilmiah Pengabdian dan Inovasi (Desember)
Publisher : Insan Kreasi Media

The service program is one of the obligations of the implementation of the tri dharma of higher education that must be carried out. The Bumigora University service team has successfully carried out service at Yarsi Mataram Kindergarten. This result is to increase awareness of the importance of saving from an early age, the team provides socialization through playing and singing, storytelling (media storytelling) which in the story adds to the benefits of saving for children in the future, and quizzes. Teaching the importance of saving from an early age can shape children's character, children will be more responsible for the money they have, can save more, introduce the value of money later on, children will be able to distinguish which are priority needs and which are not.

Aktivitas Antimikroba Ekstrak Etanol Daun Sirsak (Annona muricata L) Terhadap Bakteri Gram Negatif Eschericia coli I Nyoman Bagus Aji Kresnapati; Sri Winarni Sofya
Jurnal Ners Vol. 7 No. 1 (2023): APRIL 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v7i1.12996

Sirsak (Annona muricata L) merupakan salah satu tanaman herbal yang bermanfaat bagi kesehatan, diantaranya dimanfaatkan sebagai antimikroba. Penelitian ini bertujuan menguji kandungan senyawa fenolik yang memiliki aktivitas antimikroba bakteri gram negatif Eschericia coli. Daun-daun yang telah dikeringkan di ekstraksi maserasi dengan dilarutkan dengan pelarut etanol 96% selama 3x24 jam. Hasil maserat pertama dan kedua di pekatkan dengan rotary evaporator. Hasil ekstrak di tes fitokimia untuk mengetahui kandungan senyawa fenolik pada daun sirsak. Uji aktivitas antimikroba dilakukan dengan metode difusi sumuran sebanyak 4 lubang pada media yang telah di inokulasi bakteri gram negatif Eschericia coli yang masing-masing lubang terdiri lubang A disuspensi etanol 96%, lubang B antibiotik standar 0,5 %, lubang C ekstrak etanol daun sirsak (EtDS 0,5%) dan lubang D EtDS 1%. Hasil penelitian berupa daerah jernih disekitar sumuran yang diameternya di ukur dengan penggaris. Hasil penelitian berupa rerata diameter antara kelompok A, B, C, dan D yang kemudian di bandingkan zona yang lebih luas dan kekuatan aktivias zona hambatnya. Hasil penelitian menunjukkan diantara 4 kelompok perlakuan, lubang sumuran yang di suspensi antibiotik 0,5% (A) memiliki diameter zoba hambat lebih luas dengan diameter 19,5 mm, kemudian EtDS 1% (D) 11,35 mm, EtDS 0,5% (C) 6,49 dan Et (A) 1,25 mm. Hasil penelitian menunjukkan aktivitas ekstrak etanol daun sirsak 1% (D) berpotensi sebagai antimikroba bakteri gram negatif Eschericia coli, namun tidak lebih efektif dibandingkan antibiotik standar 0,5%.

Familiar Edible Flowers in Indonesia I Nyoman Bagus Aji Kresnapati; Muhammad Eka Putra Ramandha; Nurul Indriani
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 1 No. 01 (2022): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : Nusantara Scientific Medical

Flowers besides being used as ornamental plants, they can also be consumed. Flowers that can be consumed are called Edible Flowers. Edible flowers in general can be consumed directly, usually in tea or can be served in the form of processed food. Edible flowers contain phytochemical compounds such as anthocyanins, flavonoids, phenolics, carotenoids which are useful as antioxidants. Indonesia is rich in biodiversity with a variety of plant species that can grow, including edible flowers. There is diversity, but only a few edibles that can grow and are familiar to Indonesian people will be reviewed in this article.

PERBEDAAN KADAR LIKOPEN PADA SAUS TOMAT YANG DIPRODUKSI SECARA TRADISIONAL DAN MODERN Bagus Aji Kresnapati; Baiq Yulia Hasni Pratiwi; Lalu Busyairi Muhsin
Jurnal Ilmu Kedokteran dan Kesehatan Vol 10, No 6 (2023): Volume 10 Nomor 6
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v10i6.10023

Abstrak: Perbedaan Kadar Likopen Pada Saus Tomat yang Diproduksi Secara Tradisional dan Modern. Likopen merupakan karotenoid yang mengandung pigmen dan dijumpai pada tumbuhan berwarna merah seperti pepaya, semangka, anggur merah, aprikot dan tomat. Likopen juga terdapat pada produk olahan tomat yang melalui proses pemanasan seperti saus tomat, sehingga lebih mudah diserap tubuh dibandingkan dengan tomat segar. Berdasarkan proses pembuatannya, saos tomat dibedakan 2 macam, saos tomat yang diproduksi secara modern dalam skala industri besar dan saos tomat tradisional yang diproduksi secara sederhana dalam skala industri rumahan. Salah satu kualitas saus tomat ditentukan oleh jumlah likopen yang terkandung di dalamnya. Tinggi rendahnya kadar likopen dapat menentukan tinggi rendahnya kualitas dan kuantitas tomat yang digunakan dalam pembuatan saus tomat. Tujuan dari penelitian ini adalah untuk mengetahui perbedaan kadar likopen pada saus tomat yang diproduksi secara tradisional dan yang diproduksi secara modern. Penelitian ini merupakan penelitian observasional analitik yang bertujuan untuk mengetahui perbedaan kadar likopen pada saus tomat tradisional dan modern. Hasil penelitian menunjukkan kadar likopen tertinggi pada saus tomat tradisional sebesar 3,90 mg/100 g dan terendah 0,55. mg /100 gram; kadar likopen tertinggi saus tomat modern 9,56 mg/100 g dan terendah 5,80 mg/100 g. Rerata kadar likopen saos tomat tradisional 2,54 mg/100 g dan saus tomat modern 7,75 mg/100 g. Hasil di analisis dengan menggunakan uji statistik Independent T-test yang menunjukkan adanya perbedaan yang bermakna antara kadar likopen yang dihasilkan dengan cara tradisional dan cara modern (p=0,000<0,05).

Anemia Megaloblastik: Sebuah Tinjauan Pustaka I Ketut Wisnuaji Jayawardhana; I Nyoman Bagus Aji Kresnapati
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 1 No 1 (2022): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v1i1.2422

Anemia megaloblastik merupakan anemia yang ditandai dengan membesarnya eritroblast di sumsum tulang sehingga menganggu pematangan inti sel dan pembelahan sel eritrosit. Kelainan utamanya disebabakan karena defisiensi vitamin B-12 dan asam folat sehingga sintesis DNA terganggu. Diagnosis anemia megaloblastik dilakukan melalui anamnesis, pemeriksaan fisik, dan pemeriksaan penunjang. Pengobatannya dilakukan berdasarkan etiologi yang mendasari. Semakin cepat didiagnosis, prognosisnya akan semakin baik. Penting untuk mengenali, mencegah, dan mengobati anemia megaloblastik.

The Correlation Between Smoking Behavior and The Use of “Used Cooking Oil” with Hypertension Incidences at Malimbu Coastal Area I Gede Angga Adnyana; I Nyoman Bagus Aji Kresnapati; I Putu Bayu Agus Saputra; Maruni Wiwin Diarti; Yunan Jiwintarum
Jurnal Keperawatan Terpadu (Integrated Nursing Journal) Vol 5, No 2 (2023): OKTOBER
Publisher : Jurusan Keperawatan, Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jkt.v5i2.518

Hypertension is the main risk factor that leads to cardiovascular disease such as heart attack, heart failure and stroke, which is the highest cause of death in the world. One area with high risk of hypertension is the coastal area. The famous coastal area in the Lombok is Malimbu, located in North Lombok, West Nusa Tenggara Province. This research is an analytical observational study with a cross sectional design. This study aims to determine the correlation between smoking behavior and use of “used cooking oil” and the incidence of hypertension. Samples in this study were 70 people (n=70), and was taken using accidental sampling technique. Data were analyzed using chi-square. The results showed that the incidence of hypertension was 48% of the 70 respondents. Most of the respondents (70%), had no history of hypertension in their family. This research shows that there is no correlation between smoking behavior and the incidence of hypertension (p=0.807) with PR=1.156 (0.354 - 3.797). The use of “used cooking oil” was also found to be not correlated with the incidence of hypertension (p=0.632) with PR=1.275 (0.486 - 3.345). Although several previous studies showed that the smoking behavior and the use of used cooking oil correlate to hypertension, but this study result shows different data. This can be caused by other factors. Future research needs to examine the characteristics of smokers that may be related to the incidence of hypertension

Evaluasi Tingkat Kepatuhan Penggunaan Obat Antiepilepsi (OAE) terhadap Fungsi Kognitif Anak Anida, Rizki Putri Ayu Dwi; Kresnapati, I Nyoman Bagus Aji; Pratiwi, Baiq Yulia Hasni
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 3 No 1 (2024): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v3i1.4366

Epilepsy is a chronic brain disorder with various causes characterized by recurrent attacks. Epilepsy can affect all ages, including children, which affects around 40%-50%. Epilepsy can have an impact on memory disorders, either caused by symptoms of epilepsy itself, antiepileptic drugs (AEDs), psychosocial factors, or comorbidities. Patients with epilepsy are generally advised to consume AEDs for more than 3 months. This antiepileptic treatment takes a long time, so it is very susceptible to causing patient non-compliance in taking AEDs. Therefore, this study aims to determine the level of compliance of pediatric epilepsy patients and whether there is a relationship between compliance and the cognitive function of pediatric patients. In this study, 54 respondents were used from the Mataram City Hospital polyclinic. Compliance was measured using the Morisky Medication Adherence Scale 8 item (MMAS-8) questionnaire and cognitive function measure using the Indonesian version of the Montreal Cognitive Assessment (MoCA-Ina). The result based on the MMAS-8 shows that 7.4% of respondents had high compliance, 61.1% had moderate compliance, and 31.5% had low compliance. Data analysis used the Chi-Square test with α = 0.01 and obtained a significance value (p-value = 0.329). Based on these results, it can be concluded that the level of compliance is moderate, and there is no relationship between compliance and cognitive function.

Ekstrak Buah Lerak (Sapindus rarak) sebagai Sabun Antibakteri yang Ramah Lingkungan Novitarini, Novitarini; Kresnapati, I Nyoman Bagus Aji; Akmi, Alfarizi Muzaifa
Jurnal Biotek Vol 12 No 2 (2024): DESEMBER
Publisher : Department of Biology Education of Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jb.v12i2.51245

Synthetic surfactants contribute to environmental pollution and can cause skin irritation, highlighting the need for natural biosurfactants. Lerak fruit (Sapindus rarak) shows promise as a biosurfactant due to its 28% saponin content and potential antibacterial activity. This study aimed to evaluate the antibacterial activity of lerak fruit extract using three parameters: inhibition zone, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) against Staphylococcus aureus (Gram-positive) and Pseudomonas aeruginosa (Gram-negative). The research utilized a Posttest Only Control Group Design to test the antibacterial activity of lerak fruit extract against skin-surface normal flora, specifically Staphylococcus aureus and Pseudomonas aeruginosa. All antibacterial activity results were analyzed using One-Way ANOVA in SPSS IBM version 22. The study found the MIC to be 6.25% for Gram-positive bacteria and 1.56% for Gram-negative bacteria. The MBC was determined to be 25% for Gram-positive bacteria and 50% for Gram-negative bacteria. At a 50% concentration, the inhibition zones against Gram-positive and Gram-negative bacteria were 21.53 mm and 22.13 mm, respectively. These results demonstrate that lerak fruit extract possesses strong antibacterial activity against both Gram-positive and Gram-negative bacteria. This research provides a foundation for developing environmentally friendly antibacterial soap formulations using lerak fruit extract.

Co-Authors Akmi, Alfarizi Muzaifa Ana Rahmatyar Anam, M Khairul Anida, Rizki Putri Ayu Dwi Anjani, Desak Sri Ayu Aryani , R . Ayu Ida Baiq Dinda Puspita Ayu Baiq Yulia Hasni Pratiwi Eka Nurul Qomaliyah Hairul Hairul I Gede Angga Adnyana I GEDE ANGGA ADNYANA I Ketut Wisnuaji Jayawardhana I Putu Bayu Agus Saputra Indri Safitri Jayawardhana, I Ketut Wisnuaji Kurniawan, Nadi Maharani, Reyna Maruni Wiwin Diarti Maruni Wiwin Diarti Muchsin, Lalu Busyairi Mudawil Qulub Muhammad Eka Putra Ramandha Muhammad Haris Nasri Muhsin, Lalu Busyairi Nikendra, Ni Nengah Naia Novitarini Novitarini Novitarini, Novitarini Nurul Indriani Ramadhani, Muhammad Wisda Pradja Rozikin Sabariah Salsabila Yunita Kurniawan Siti Khaerunnisa Sofya, Sri Winarni Sri Winarni Sofya Yunan Jiwintarum Yunan Jiwintarum

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