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Journal Of Carbazon
Published by Universitas Syiah Kuala
ISSN : 29885744     EISSN : 29885744     DOI : 10.24815/jocarbazon
Core Subject : Science,
Biochemistry, Genetics & Molecular Biology Chemistry Materials Science & Nanotechnology
Journal of Carbazon is a journal published by Chemistry Department, Faculty of Science and Mathematics, USK Banda Aceh. The journal aims to disseminate cutting-edge research in all areas of chemistry both theoretical and experimental studies. Journal of Carbazon provides readers with original research articles and reviews. We welcome articles coming from Indonesia and overseas, capturing the rapid development of chemistry, including: Theoretical and computation chemistry Environmental chemistry Material, composite and polymer chemistry Organic synthesis and natural product chemistry Inorganic Chemistry Food and medical chemistry Biochemistry Analytical chemistry The author is solely responsible for the content of published articles and understood that submitted work is based on original results which has not been published previously. All accepted articles are reviewed by a team of experts.
Arjuna Subject : Kimia(semua kategori) - Kimia (Lain-Lain)
Articles 5 Documents
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Search results for , issue "Vol 2, No 2 (2024): December 2024" : 5 Documents clear
Characterization of Thermophilic Novel-Rare Actinobacteria from Hot Springs and Compost as an Unique Secondary Metabolite Producer Maghfirah, Ruhul; Kemala, Pati; Astryna, Syarifah Yanti
Journal of Carbazon Vol 2, No 2 (2024): December 2024
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jocarbazon.v2i2.42883

Abstract

This review aims to explain in more detail about the Actinobacteria and it secondary metabolites. Some species of Actinobacteria can live in extreme environments such as high acid, high base, high salt and even high temperatures. Actinobacteria mainly of the genus Streptomyces sp. has been known to produce bioactive compounds such as antibacterial, antifungal, anticancer, antitumor, anticytotoxic, anti-inflammatory, anti-parasitic, anti-malarial, antiviral and antioxidant. This study reviews various research findings on Actinobacteria species and their ability to thrive in extreme environments. It also reviews the findings of bioactive compounds isolated from Actinobacteria and their potential applications. Some species in the genera Streptomyces, Thermonospora, and Thermoactinomyces have optimal growth temperatures above 55C and are categorized as thermophilic. More than 30,000 bioactive compounds that have been isolated are derived from Actinobacteria and 80% are from the genus Streptomyces sp. Benzastatin C and 3-Chloro-Tetrahidroquinolon are new antivirals isolated from Streptomyces nitrosporeus. Essramycin is a novel antibiotic that shows activity against Gram positive and Gram negative bacteria. Chandrananimycin A isolated from Actinomadura sp. and N-(2-hydroxyphenyl)-2-Phenazinamin (NHP) isolated from Nocardia dassonvillei are novel antibiotics that can be used as antifungals, antialgas, antibacterials and anticancer. The potential of Actinobacteria in producing bioactive compounds can advance the field of science and technology in the future and become an alternative to overcome the problem of resistance to pathogenic microorganisms are increasing.
The potential of fly ash-based geopolymers as an environmentally friendly construction material solution: A review Mazwan, Mazwan; Fajri, Fajri
Journal of Carbazon Vol 2, No 2 (2024): December 2024
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jocarbazon.v2i2.43510

Abstract

The use of environmentally friendly construction materials has been increasing in response to the demand for sustainable development. Fly ash-based geopolymers have emerged as an innovative and sustainable solution in the construction industry. This article discusses the potential use of fly ash-based geopolymers, covering their characteristics, synthesis process, advantages, challenges, and future development prospects. This research adopts a literature review approach, referencing various international and national journals. The study findings reveal that fly ash geopolymers possess high mechanical strength, corrosion resistance, and significantly lower carbon emissions compared to conventional concrete. This potential provides significant opportunities in supporting more environmentally friendly infrastructure development.
Montmorillonite-Chitosan as a Biocomposite Encapsulation for Ibuprofen in Drug Release Afifi, Muhammad Ridho; Irwandi, Dodi; Safitri, Eka; Syafei, Dedri; Ngapa, Yulius Dala
Journal of Carbazon Vol 2, No 2 (2024): December 2024
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jocarbazon.v2i2.42149

Abstract

Ibuprofen is a type of anti-inflammatory drug. However, its use faces challenges in the medical field due to its rapid degradation, low bioavailability, limited solubility, and high permeability. One approach to address these issues is the encapsulation of ibuprofen by coating it with Montmorillonite (MMT) and Chitosan (CS) to control the released dosages of Ibuprofen. MMT and CS were used to coat ibuprofen using four methods. These methods were compared through dispersing MMT in water, mixing with chitosan, and combining ibuprofen under different conditions. Subsequently, tests were conducted on ibuprofen coated with MMT-CS, including morphology, efficiency, and release profile. The most effective method for controlling ibuprofen release was shown in the third method, where MMT-CS was first modified, and then ibuprofen was added to the modified MMT-CS. This method showed the highest encapsulation efficiency of 61.51%, the best release profile with 21.59% ibuprofen release within 90 minutes, and the most uniform encapsulation morphology. These studies indicated that the MMT-CS biocomposite effectively improves ibuprofen release efficiency, potentially enhancing therapeutic outcomes while reducing side effects of ibuprofen.
Modification of Montmorillonite with Chitosan as Mercury Metal Adsorbent Julinawati, Julinawati; Nisa, Salasatun; Fathurrahmi, Fathurrahmi; Mustafa, Irfan; Saleha, Sitti; MZ., Kartika; Suryati, Suryati
Journal of Carbazon Vol 2, No 2 (2024): December 2024
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jocarbazon.v2i2.42230

Abstract

Modification of montmorillonite with chitosan as an adsorbent of mercury (Hg) metal has been carried out. This study aims to determine the characteristics of the adsorbent, the optimum adsorption capacity of Hg metal, and its adsorption isotherm equation. The optimum conditions for Hg metal adsorption are determined by varying the contact time and pH of the solution. Variations in adsorbate concentration are carried out to determine the adsorption isotherm. Characterization of the adsorbent using FTIR shows the presence of -OH, Si-O, Al-O, C-C, and N-H groups. The optimum conditions for mercury metal adsorption by montmorillonite modified with chitosan occur at a contact time of 80 minutes, and a pH of 4. The adsorption process of mercury metal ions using montmorillonite adsorbent modified with chitosan satisfies both isotherm models, namely the Langmuir and Freundlich isotherms with R2 values of 0.971 and 0.967 respectively, and a maximum adsorption capacity of 13.513 mg/g. The regeneration test showed that the adsorbent can be reused for the absorption of mercury metal ions.
Evaluation of Antifeedant Activity in Methanol Extracts of Zingiberaceae Species Against Epilachna sparsa Purnama, Agnia; Nurdin, Nurdin; Ratna, Ratna; Farida, Mutia
Journal of Carbazon Vol 2, No 2 (2024): December 2024
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jocarbazon.v2i2.42458

Abstract

Cellulosenanofibrils (CNF) is a new generation material that has high performance, good physics and medical properties and is a renewable material that has been developed from various sources using the acid hydrolysis method. CNF synthesis is generally obtained from logs that have a high amount of cellulose fiber. Cellulose nanofibrils (CNF) from arabica coffee skins have great potential to be developed as raw materials for medicines, which function as wound healing agents, surgical sutures, diet medicines, and skin softeners. CNF is produced from Arabica coffee skin through delignification, namely the removal of lignin and hemicellulose by extraction with alkali until -cellulose is obtained, then CNF is synthesized through hydrolysis using dilute acid. From the coffee skin extraction results, a high cellulose yield was obtained, reaching above 24.30% and crystallinity reaching 79.60%. Hydrolysis by 10%, 12% and 15% HCl with a reaction time of 2 hours, the respective crystallinity was 80.66; 79.06; and 77.69%.

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