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Jurnal MedScientiae
Published by Universitas Kristen Krida Wacana
ISSN : -     EISSN : 28291166     DOI : https://doi.org/10.36452/jmedscientiae
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Jurnal MedScientiae adalah jurnal yang dikelola oleh Fakultas Kedokteran dan Ilmu Kesehatan Universitas Kristen Krida Wacana. Jurnal ini mempublikasikan artikel-artikel secara open access dalam lingkup bidang kedokteran dan kesehatan seperti kedokteran dasar, bioetika kedokteran, biologi sel, biologi molekuler, genetika, fisiologi, biokimia, bioinformatika, anatomi, farmakologi, kesehatan masyarakat, dan ilmu biomedik lainnya. Tim editorial menerima naskah berupa artikel penelitian, literature dan systematic review, dan laporan kasus. Naskah yang dikirimkan hendaknya belum pernah diterbitkan sebelumnya di jurnal maupun media yang lain dan disiapkan sesuai dengan template atau format yang telah ditentukan. Setiap naskah yang memenuhi kriteria jurnal akan direview oleh pakar yang sesuai (peer reviewer). Jurnal MedScientiae tidak mengenakan biaya selama proses mulai dari penerimaan naskah hingga publikasi. Jurnal MedScientiae terbit 3 kali dalam satu tahun, yaitu pada bulan April, Agustus dan Desember dengan cakupan keilmuan yang telah disebutkan di atas. Edisi pertama jurnal akan diterbikan di bulan Mei tahun 2022 dengan nomor ISSN 2829-1166.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 21 Documents
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Search results for , issue "Vol. 3 No. 2 (2024): Agustus" : 21 Documents clear
DESCRIPTION OF THE USE OF EYE PROTECTION EQUIPMENT AND THE DIRECT EFFECT OF USE OF WELDING ON THE EYES OF WELDER WORKERS Saputri, Novricia Agnes
Jurnal MedScientiae Vol. 3 No. 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.2974

Abstract

A welder is anyone, amateur or professional, who uses welding equipment. A metalsmith who specialize input the ingredients together and usually metal. In carrying out their work, workers will be constantly exposed to high-intensity welding light. Welding workers who do not use proper eye protection can experience direct effects from welding. This literature review is a literature review that uses the method of searching articles in databases, such as PubMed, Google Scholar and manual searches which are then analyzed as many as 10 of the 137 journals obtained. The results showed that the most common use of eye protection was welding goggles with the highest prevalence of eye protection in welding workers, namely 98.4%. The prevalence of complaints in the eyes of welders with the largest prevalence is 74.5%. Welders experience eye complaints in the form of watery eyes, red eyes, eye strain, corneal injuries, and conjunctival disorders and presbyopia. The immediate effect that often occurs is in the form of complaints of watery eyes and then experiencing red eyes.
Prevalensi Miopia pada Mahasiswa FKIK UKRIDA Angkatan 2019 dan Hubungannya dengan Pembelajaran Daring selama Masa Pandemi Putri, Dhenisa Eka Kurnia
Jurnal MedScientiae Vol. 3 No. 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3006

Abstract

Myopia is a common vision condition in which a person can see nearby objects clearly, but objects further away are blurry. In Indonesia, the prevalence of refractive errors ranks first, covering 25% of the population or around 55 million people. In December 2019, the novel coronavirus spread rapidly in China and around the world. Social restriction and regional quarantine policies have the potential to limit people from carrying out activities, especially in educational institutions. Purpose: to determine the prevalence of myopia sufferers and their relationship with online learning. Methods: using a total sampling technique with a cross sectional method with 162 respondents. Results: It was found that respondents who used devices for a duration of <4 hours and a distance of <30 cm tended not to experience myopia (P>0.05). By looking at the results obtained through the Chi-Square test, it can be concluded that there is no relationship between online learning and myopia. Conclusion: it can be concluded that there is no relationship between online learning and myopia in active students of FKIK UKRIDA class of 2019 and the prevalence of myopia in active students of FKIK Ukrida class of 2019 is 60.1%.
Potensi Tepezza (Teprotumumab) dalam Pengobatan Penyakit Mata Tiroid Aktif (TED) Rukmana, Dewi Samudra Putri Aliffa; Ramzi, Rani Nurmala; Dhuarte, Jevon; Jaya, Fitra; Anugrahsari, Santi
Jurnal MedScientiae Vol. 3 No. 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3010

Abstract

Abstract Active Thyroid Eye Disease (TED) is a medical condition involving swelling of the muscles, tissues, and fats around the eyes. This can lead to serious symptoms including double vision and vision loss. Tepezza (Teprotumumab) is an innovative therapy that inhibits the insulin-like growth factor 1 receptor (IGF-1R) and has been approved for TED treatment. Teprotumumab works by reducing inflammation and TED symptoms. Pharmacokinetic studies indicate that this drug can be effectively administered via intravenous infusion. Various studies have shown that teprotumumab can significantly reduce proptosis, diplopia, and clinical activity of TED. This therapy has proven effective in various patient groups, including those with long-standing TED and those unresponsive to other treatments. Teprotumumab holds a promising breakthrough in TED management, improving the quality of life for individuals affected by this disease. Further studies are needed to fully understand the mechanism and potential of teprotumumab in TED treatment.
Relations Between Stress Level and the Occurrence of Constipation to Medical Students Arsita, Elli; Wician, Fendra; Mamudi, Chrispian Oktafbipian; Mahonny, Glorie Libertikha
Jurnal MedScientiae Vol. 3 No. 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3069

Abstract

Stress can be experienced by anyone. The number of events is increasing every year. This isevidenced from the results of Basic Health Research in 2013 and 2018, namely an increase in theprevalence of mental emotional disorders in Indonesian population aged ≥ 15 years from 6percent to 9.8 percent. Stress can have a negative impact on the human body both physically andpsychologically. One of the effects of stress on the body is constipation. Unfortunately not muchliterature discusses stress and constipation in more detail. This study aims to determine whetherthere is a relationship between stress levels and constipation in the seventh semester students ofthe 2016 Faculty of Medicine and Health Sciences at Ukrida. This research uses analytic studymethod with cross-sectional approach. Sampling is done by consecutive sampling method. Thestudy was conducted in December 2019 at the Ukrida’s medical campus. 150 out of 206 studentsof 2016 from Ukrida Faculty of Medicine and Health Sciences who are in their seventh semester,are included in the inclusion criteria. The research material is primary data in the form of aConstipation Scoring System questionnaire and Perceived Stress Scale. The results showed arelationship between stress levels and constipation. This was obtained from the Chi Square testcalculation which was calculated using the SPSS computer program, where the p value was 0.01(p <0.05).
Current Management of Fluorometholone Steroids in Pediatric Vernal Conjunctivitis: A Literature Review Fajar, Muhammad Fauzi; Siallagan, Maria; Nabighah, Gladis Salsabila Najla; Wijaya, Pande I Gede Indra; Anugrahsari, Santi
Jurnal MedScientiae Vol. 3 No. 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3079

Abstract

Vernal conjunctivitis is a rare allergic eye disease, usually affecting children in the prepubertal years and can last between 5 to 10 years. Treatment of this condition is often challenging, requiring effective therapies to reduce symptoms. This literature review, conducted between 2015 and 2023, aimed to evaluate the effectiveness of fluorometholone steroid use in the treatment of pediatric vernal conjunctivitis. Recent studies comparing the effectiveness of Fluorometholone 0.1% in the treatment of Vernal Keratoconjunctivitis (VKC) were analyzed. The results showed that Fluorometholone was effective compared to Cyclosporine in reducing VKC symptoms. However, the use of Fluorometholone should be done with caution due to potential side effects such as increased intraocular pressure and risk of infection.Fluorometholone is an effective treatment option for vernal conjunctivitis in children. However, it is important to have close monitoring by an ophthalmologist to avoid serious side effects. With careful monitoring and proper dose adjustment, Fluorometholone can be a safe and effective therapy in managing this condition.  
Pharmacotherapy Study Of Albendazole And Mebendazole For Soil Transmitted Helminths Infections In Children Susanto, Inneke Kusumawati; William, William; Agatha, Nabila
Jurnal MedScientiae Vol. 3 No. 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3109

Abstract

Soil Transmitted Helminths (STH) infection is a nematode infection of the intestine that requires soil for its transmission. The worms that cause Soil Transmitted Helminths infection include; Ascaris lumbricoides, Trichuris trichiura, hookworms (Necator americanus and Ancylostoma duodenale. The incidence of STH infection is quite high with the highest spread of STH infection in the child age group. Treatment of cases of STH infection is by administering antihelmintic drugs or worming drugs. Although there are four The drugs recommended by WHO, only the two drugs most often used in the treatment of STH infections, namely albendazole and mebendazole. Both drugs have been used for more than 30 years, but cases of STH infection still have a high incidence. That is why this literature review was written aims to describe the efficacy of the two drugs for STH infection in children so that their effectiveness can be assessed.The research method used was a literature review, a literature search was sourced from Proquest, Google scholar, Pubmed, Elsevier and Europe PMC. keywords Albendazole, Mebendazole, Soil Transmitted Helminths Infections, Children. There are 10 selected literatures to be studied in this literature review. The results showed that albendazole had satisfactory efficacy in STH infections caused by Ascaris lumbricoides and hookworms, but reduced efficacy in Trichuris trichiura worms. Mebendazole has satisfactory efficacy in STH infections caused by Ascaris lumbricoides and Trichuris trichiura, but reduced efficacy in hookworms. Albendazole and mebendazole does not cause side effects.
Potensi Sekretom Mesenchymal Stem Cell pada Terapi Regeratif Penyakit Paru Fibrosis Kartika, Ronald Winardi; Timotius, Kris Herawan
Jurnal MedScientiae Vol. 3 No. 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3142

Abstract

Fibrosis lung diseases such as chronic obstructive pulmonary disease, acute lung injury and post-Covid 19 fibrosis lung disease are considered as major health problems in the last decade. Cellular therapy with Mesenchymal Stem Cells (MSC) offers a novel therapeutic approach for fibrosis lung disease associated with anti-inflammatory, immunomodulatory, regenerative, pro-angiogenic and anti-fibrotic properties. Such therapeutic effects may be attributed to the MSC-secretome, which is made of free soluble proteins and extracellular vesicles (EVs). This review summarises some recent literature findings related to the efficacy and safety of MSC-derived products in pre-clinical models of lung diseases, demonstrating the biologically active substances contained in the MSC-secretome and its mechanisms involved in tissue regeneration. A perspective view is given on the secretome being a high-quality, safe and effective medicinal product,  
GAMBARAN FOTO THORAX DAN DISTRIBUSI BAKTERI PATOGEN PADA PASIEN PNEUMONIA Finaldi, Fauzan
Jurnal MedScientiae Vol. 3 No. 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3144

Abstract

Pneumonia is an acute infectious or inflammatory disease that affects the lung parenchyma which can be caused by microorganisms such as bacteria, viruses and fungi. This study aims to determine the chest x-ray picture and the distribution of pathogenic bacteria in pneumonia patients, as well as to look at the chest x-ray picture of certain pathogens. The method in this study is to search for articles via Google Scholar and Pubmed. The results showed that the distribution of pathogenic bacteria in pneumonia cases varied, but the most common bacteria that cause pneumonia were Streptococcus pneumoniae, Klebsiella pneumoniae, and Mycoplasma pneumonia. On chest x-rays, the chest x-ray images obtained are quite diverse, and the commonly found results are consolidation, infiltrates and pleural effusion. In patients with pneumonia due to Mycoplasma pneumoniae, the chest x-ray picture that is often found is lobar pneumonia or lobar consolidation.
Risk Factors for Urinary Incontinence in the Elderly Regina, Kezia; Tamba, Ernawaty; Soesanto, Aries
Jurnal MedScientiae Vol. 3 No. 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3145

Abstract

Individuals aged sixty years or older who require more care are referred to as seniors. Urinary incontinence in the elderly is a common problem. Uncontrolled urine production is known as urinary incontinence. Elderly people often experience this health problem. As we age, pelvic muscles weaken, resulting in changes in the anatomical function of the urinary tract organs and an increased risk of urinary incontinence. The aim of the research is to review related research on risk factors for urinary incontinence in the elderly. This research uses literature study. Where using a search for journals in Indonesian and English for 2013 - 2023 which was carried out using the WHO, PubMed, NCBI databases with the keywords Urinary incontinence in the elderly and found 10 journals selected according to the inclusion criteria with elderly subjects ≥ 45 years, cross sectional design and descriptive. The results show that urinary incontinence in the elderly has a significant relationship with risk factors for urinary incontinence such as diabetes, smoking, vaginal delivery and quality of life in the elderly. It can be concluded that there is a relationship between the two variables and most studies show that urinary incontinence is an important factor that can cause stress in the elderly.  
Inhibitor Transient Receptor Potential Vanilloid Type 1: Penggunaan Topikal pada Berbagai Dermatosis Muhammad, Parikesit; Paramitha Wibawa, Larisa; Keumala Budianti, Windy; Legiawati, Lili; Menaldi, Sri Linuwih; Rosdiana, Dewi Selvina
Jurnal MedScientiae Vol. 3 No. 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3179

Abstract

Transient receptor potential vanilloid type 1 (TRPV1) plays an important role in the pathophysiology of pruritus and pain. TRPV1 inhibitors can reduce the sensation of itching and pain by blocking nociceptive signals from peripheral nerve fibers to the central nervous system. Topical TRPV1 inhibitors is also thought to improve skin barrier function. Therefore, TRPV1 inhibitors are considered as potential therapy in various dermatoses. Topical TRPV1 inhibitors that are currently being studied are asivatrep for atopic dermatitis and trans-4-tert-butylcyclohexanol for various dermatoses associated with sensitive skin. Further studies with better quality and longer duration are needed to assess the efficacy and safety profile of TRPV1 inhibitors.

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