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Jurnal MedScientiae
Published by Universitas Kristen Krida Wacana
ISSN : -     EISSN : 28291166     DOI : https://doi.org/10.36452/jmedscientiae
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Jurnal MedScientiae adalah jurnal yang dikelola oleh Fakultas Kedokteran dan Ilmu Kesehatan Universitas Kristen Krida Wacana. Jurnal ini mempublikasikan artikel-artikel secara open access dalam lingkup bidang kedokteran dan kesehatan seperti kedokteran dasar, bioetika kedokteran, biologi sel, biologi molekuler, genetika, fisiologi, biokimia, bioinformatika, anatomi, farmakologi, kesehatan masyarakat, dan ilmu biomedik lainnya. Tim editorial menerima naskah berupa artikel penelitian, literature dan systematic review, dan laporan kasus. Naskah yang dikirimkan hendaknya belum pernah diterbitkan sebelumnya di jurnal maupun media yang lain dan disiapkan sesuai dengan template atau format yang telah ditentukan. Setiap naskah yang memenuhi kriteria jurnal akan direview oleh pakar yang sesuai (peer reviewer). Jurnal MedScientiae tidak mengenakan biaya selama proses mulai dari penerimaan naskah hingga publikasi. Jurnal MedScientiae terbit 3 kali dalam satu tahun, yaitu pada bulan April, Agustus dan Desember dengan cakupan keilmuan yang telah disebutkan di atas. Edisi pertama jurnal akan diterbikan di bulan Mei tahun 2022 dengan nomor ISSN 2829-1166.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 249 Documents
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Pengaruh Pemberian Steroid Topikal Terhadap Tekanan Intra Okular : Sebuah Tinjauan Pustaka Lauw, Jessica Amelia; Muthia, Annisa Sri Rachma; Pangaribuan, Beatric Ruth Fransiska; Anugrahsari, Santi
Jurnal MedScientiae Vol 3 No 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3162

Abstract

The use of topical corticosteroids, especially in the periocular area, has been associated with increased intraocular pressure (IOP), potentially leading to glaucoma and other eye complications. This study evaluated the risk of IOP elevation due to topical corticosteroid use and its influencing factors. This study is a literature review investigating the relationship between topical corticosteroid use and IOP elevation. Data were collected from studies reporting the effect of topical corticosteroids on IOP, including the type of steroid, duration of use, frequency of administration, and patient age. The findings suggest that the use of topical corticosteroids can lead to a significant increase in IOP, with the risk varying depending on the type of steroid, duration, and frequency of use, as well as individual patient characteristics such as age. Although some studies showed a significant increase in risk, other results showed minimal risk, suggesting the need for close monitoring of IOP in patients using topical corticosteroids. The use of topical corticosteroids in the periocular area requires careful consideration of the potential risk of increased IOP. It is important to choose steroids with low anti-inflammatory potential and monitor IOP regularly to reduce the risk of IOP-related side effects. Further studies are needed to fully understand the risks associated with using periocular topical corticosteroids and develop guidelines for safe use.
Tinjauan Pustaka Penggunaan Gawai dengan Kejadian Miopia Anugrahsari, Santi; Nugraha, Abraham William; Septrilla, Gladys; Veronica Agrippina
Jurnal MedScientiae Vol 3 No 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3164

Abstract

Lifestyle changes during the pandemic has impacted the lives of almost every human being in the world. This lifestyle changes, especially the increase in the duration and frequency of gadget use for everyday routine can cause various unwanted side effects such as refractive disorders, especially myopia. This study aims to evaluate the correlation between gadget use and myopia and other relevant ocular biometric parameters such as axial length (AL) and spherical equivalent (SE). The literatures used in this study is taken from an electronic database using NCBI, ProQuest and Google Scholar with English keywords “Gadget”, “Myopia”, and “Vision Impairment” and in Indonesian “Gawai”, “Miopi”, dan “Kelainan Refraksi ”. The articles found was published between January 2012 and Juni 2022, which was then sorted according to the objective of this study and we found fifteen journals that we include in this study. The distance in which gadgets were used was found to have a correlation with myopia. Laying down while using gadgets was also found to be correlated with myopia. Meanwhile, the duration of gadget use has not been found to be correlated with myopia. Gadget use can be one of the risk factors for refractive disorders. Based on the literature we collected, it was found that gadget use distance less than 30 cm and laying down while using gadgets has a correlation with refractive disorders meanwhile the duration of gadget use was found to not be correlated with refractive disorders.
Inhibitor Transient Receptor Potential Vanilloid Type 1: Penggunaan Topikal pada Berbagai Dermatosis Muhammad, Parikesit; Paramitha Wibawa, Larisa; Keumala Budianti, Windy; Legiawati, Lili; Menaldi, Sri Linuwih; Rosdiana, Dewi Selvina
Jurnal MedScientiae Vol 3 No 2 (2024): August
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3179

Abstract

Transient receptor potential vanilloid type 1 (TRPV1) plays an important role in the pathophysiology of pruritus and pain. TRPV1 inhibitors can reduce the sensation of itching and pain by blocking nociceptive signals from peripheral nerve fibers to the central nervous system. Topical TRPV1 inhibitors is also thought to improve skin barrier function. Therefore, TRPV1 inhibitors are considered as potential therapy in various dermatoses. Topical TRPV1 inhibitors that are currently being studied are asivatrep for atopic dermatitis and trans-4-tert-butylcyclohexanol for various dermatoses associated with sensitive skin. Further studies with better quality and longer duration are needed to assess the efficacy and safety profile of TRPV1 inhibitors.
Prevalensi Kista Ovarium Di RS Swasta di Jakarta Barat pada tahun 2017-2021 Lauw, Jessica Amelia; Christina, Shintia; Pasaribu, Donna Mesina
Jurnal MedScientiae Vol 3 No 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3189

Abstract

Ovarian cysts are generally divided into functional cysts, endometriosis, and neoplasm cysts with benign, borderline and malignant properties. Ovarian cysts occur in 82% of women of productive age. In general, ovarian cysts found are benign and the rest are a journey to malignancy. Detailed prevalence rates regarding ovarian cysts for each type of ovarian cyst have not been found in Indonesia, especially at Hermina Daan Mogot Hospital This type of research is descriptive, using a cross sectional design. This research was carried out at Hermina Daan Mogot Hospital from 2017 – 2021.From the results obtained, the most histopathological diagnosis was endometriosis with a total of 117 subjects (45.5%). The largest age group is 36.7 – 45.6 years old with 96 subjects and the least age category is ≥ 65.7 years old with 8 subjects. The most common type of ovarian cyst is endometriosis. The highest age range is 36.7 – 45.6 years.
Persepsi Mahasiswa Kedokteran Ukrida Angkatan 2020 terhadap Proses Pembelajaran Daring Arsana, Gabriel Ferdinan; Hartono, Budiman; Josephine, Jodie
Jurnal MedScientiae Vol 3 No 2 (2024): August
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3204

Abstract

Online learning is leaning that utilizes online media or the internet in learning. The learning process that is carried out online makes students’ psychological and mental activities trained in the environment, which results in a pile of changes in knowledge and understanding, skills and attitude values. Perception is a point of view or understanding of material or information received during learning activities. This study has four operational definitions, namely online learning, problem-based learning, skills lab, and integration. From the results of this study, it was concluded that students have perceptions of online learning satisfaction because students can study anywhere during the pandemic and can understand the material presented by lecturers. Based on the level of achievement of student respondents, they can take part in online learning without affecting the learning process or behavior.
Effectiveness of Prednisolone Acetate Eye Drops 1% in Improving the Final Vision of Anterior Uveitis Patients Anugrahsari, Santi; Celine, Callysta; Saragih, Putri Arsya; Arsana, Gabriel Ferdinan
Jurnal MedScientiae Vol 3 No 2 (2024): August
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3206

Abstract

Anterior uveitis is the most common classification of uveitis and can result in decreased vision, even blindness in sufferers. Therefore, this literature review was carried out to determine the effectiveness of topical steroids, namely prednisolone acetate 1%, in improving final vision in anterior uveitis patients. In this literature review, 6 articles were found from electronic databases in PubMed and Google Scholar, which were selected based on the specified inclusion and exclusion criteria. The study's results stated that prednisolone acetate 1% eye drops effectively improved final vision in anterior uveitis patients. Further research regarding the effectiveness of prednisolone acetate 1% needs to be carried out in a broader scope, with various patient characteristics, to make the research results more accurate.
Literature Review Exposure To Electric Cigarette Smoke (Vape) On Cerebrum And Rat Behavior Woen, Aurelia Wirasdita; Sumbayak, Erma Mexcorry
Jurnal MedScientiae Vol 3 No 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3209

Abstract

E-cigarettes are a modern form of conventional cigarettes, many have used them because they contain nicotine and various flavors so that young people like them. This literature aims to determine the effects of exposure to e-cigarettes containing nicotine or not on the cerebrum and behavior of experimental animals. The method of making literature in the form of literature review with a comprehensive approach. By searching for articles or journals in research journal databases, internet, articles. The database search used was Google Scholar, Pubmed, Proquest. Exposure to e-cigarette smoke can cause damage to the cerebrum, such as inflammation to necrosis, besides it can cause decreased cognitive abilities, behavior to emotional. E-cigarettes contain various components that are dangerous if consumed for a long time can cause dependence, decreased cognitive memory function and emotional changes. Exposure to secondhand smoke also causes inflammation, damage or necrosis. Nicotine also plays a role in this.
AN OVERVIEW OF KNOWLEDGE, ATTITUDE AND BEHAVIOR ABOUT USING SELF PROTECTIVE EQUIPMENT IN TOLL ROAD CONSTRUCTION WORKERS PT.X, LAMPUNG IN OCTOBER 2018 Winata, Susanty Dewi; Kurniawan, Hendrik; Sutanti, Yosephin Sri; Purnamawati, Purnamawati; Situmorang, Priscilla Revina
Jurnal MedScientiae Vol 3 No 2 (2024): August
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3221

Abstract

The behavior of using Personal Protective Equipment (PPE) in construction sector workers in Indonesia is still not good, this is indicated by the still high mortality and disability due to workplace accidents. There are still many workers who do not use PPE when working based on several factors, including the lack of company policy and supervision and aspects of the workers themselves. The purpose of this study was to see an overview of the knowledge, attitudes and behavior of construction workers about the use of PPE in PT. X, Lampung in 2018. The research design used in this study was a cross-sectional design that was descriptive in nature. This study used a sample of 50 people and analyzed univariately. The results of this study show a picture of knowledge, attitudes and good behavior about the use of PPE. In addition, the highest age for workers is> 30 years, the highest level of education is Higher Education and the lowest is elementary school and the highest level of education is high school / vocational school, the highest period of employment is ≤ 10 years. From the results of this study it can be concluded that respondents have a high level of awareness about the importance of using PPE to avoid the risk of workplace accidents.
Efektivitas COX-2 Inhibitor Sebagai Preemptive Analgesia pada Operasi Total Knee Arthoplasty Siriwa, Sultan Yosua; Suparto, Suparto; Ciulianto, Rudy
Jurnal MedScientiae Vol 3 No 2 (2024): August
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3247

Abstract

Post-operative pain, especially TKA procedures, is a problem that is often encountered. The use of adequate analgesics is the main treatment to reduce the side effects of pain, namely immobilization, decreased range of motion (ROM), increased risk of thromboembolism and decreased success rate of rehabilitation. Several previous studies reported the possibility of a significant therapeutic effect on the postoperative pain response by using preemptive analgesia methods with cyclooxygenase-2 inhibitors (COX-2 inhibitors). The aim of this study was to determine the effectiveness of COX-2 inhibitors using the preemptive analgesia method in total knee arthroplasty surgery through a literature study. Data searches were carried out on several electronic journal databases PubMed, ProQuest and Google Scholar, with the keywords "cyclooxygenase 2 inhibitors", "COX-2 inhibitor", "celecoxib", "valdecoxib", "rofecoxib", "etoricoxib", "non- steroidal anti-inflammatory drugs”, “preoperative analgesia”, and “total knee arthroplasty”. in 2013-2022. Overall, the study showed a significant response to the use of COX-2 inhibitors in preemptive analgesia methods to suppress the pain response at rest and during knee flexion after TKA when compared with the control group. The PA method with COX-2 inhibitors has also been proven to be successful in reducing the level of use of salvatory analgesics, which indirectly indicates that pain control has been successful. COX-2 inhibitors have been proven to be effective in reducing the pain response as a preemptive analgesia method in patients undergoing TKA procedures.
Perkiraan Usia Berdasarkan Tulang Belulang Arief, Pamela; Gozali, Rowen Jayadi; Mulyono, Bethea Manuela; Widiastuti, Tri; Marcella, Laurie; Arfandi, Hanif; Karupukaro, Aprilda Yulifa Thalia Thomas; Kristhazshana, Zshananda; Precious, Heunice; Ethanelle, Lourdes; Yen, Liauw Djai
Jurnal MedScientiae Vol 3 No 2 (2024): August
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3265

Abstract

Pendahuluan: Estimasi usia kerangka manusia merupakan aspek penting dalam profil biologis yang digunakan oleh antropolog forensik untuk identifikasi individu yang meninggal. Perkiraan usia dapat dilakukan melalui beberapa metode, seperti pemeriksaan makroskopis perkembangan dan erupsi gigi, penyatuan epifisis tulang panjang, degenerasi permukaan artikular panggul, ujung tulang rusuk, dan jahitan kranial, serta analisis mikroskopis struktur tulang. Tinjauan ini bertujuan untuk mengeksplorasi serta menganalisis berbagai teknik yang tersedia untuk tujuan ini. Metodologi: Tinjauan literatur ini menggunakan referensi melalui basis data PubMed dan ResearchGate. Pengambilan data dilakukan berdasarkan alur proses, dimana diperoleh 8 sumber literatur yang relevan dengan topik penelitian. Hasil dan Pembahasan: Metode estimasi usia sering menunjukkan bias di mana usia individu yang lebih muda cenderung dilebih-lebihkan, sementara usia individu yang lebih tua diremehkan. Perubahan degeneratif pada struktur seperti ujung tulang rusuk sulit untuk ditafsirkan secara akurat dan berkontribusi terhadap kesalahan dalam estimasi usia terutama setelah usia 60 tahun. Variasi ini kemungkinan terkait dengan perbedaan gaya hidup, lingkungan, dan aktivitas. Metode menggunakan simfisis pubis lebih akurat untuk individu dewasa muda. Permukaan aurikular dapat memberikan estimasi yang memadai pada kelompok usia menengah. Gigi monoartikular dan ujung sternal iga keempat ditemukan sebagai metode yang akurat untuk individu yang lebih tua. Simpulan: Metode estimasi usia osteologis memerlukan penyesuaian dan evaluasi terus-menerus berdasarkan populasi dan faktor-faktor spesifik terkait usia. Kombinasi beberapa metode dan analisis mendalam terhadap variabel morfologis dapat meningkatkan akurasi estimasi usia, meskipun bias tetap ada terutama pada kelompok usia tua dan muda. Kata kunci: Age Estimation, Skeletal Age, Anthropology, Forensic

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