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Jurnal MedScientiae
Published by Universitas Kristen Krida Wacana
ISSN : -     EISSN : 28291166     DOI : https://doi.org/10.36452/jmedscientiae
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Jurnal MedScientiae adalah jurnal yang dikelola oleh Fakultas Kedokteran dan Ilmu Kesehatan Universitas Kristen Krida Wacana. Jurnal ini mempublikasikan artikel-artikel secara open access dalam lingkup bidang kedokteran dan kesehatan seperti kedokteran dasar, bioetika kedokteran, biologi sel, biologi molekuler, genetika, fisiologi, biokimia, bioinformatika, anatomi, farmakologi, kesehatan masyarakat, dan ilmu biomedik lainnya. Tim editorial menerima naskah berupa artikel penelitian, literature dan systematic review, dan laporan kasus. Naskah yang dikirimkan hendaknya belum pernah diterbitkan sebelumnya di jurnal maupun media yang lain dan disiapkan sesuai dengan template atau format yang telah ditentukan. Setiap naskah yang memenuhi kriteria jurnal akan direview oleh pakar yang sesuai (peer reviewer). Jurnal MedScientiae tidak mengenakan biaya selama proses mulai dari penerimaan naskah hingga publikasi. Jurnal MedScientiae terbit 3 kali dalam satu tahun, yaitu pada bulan April, Agustus dan Desember dengan cakupan keilmuan yang telah disebutkan di atas. Edisi pertama jurnal akan diterbikan di bulan Mei tahun 2022 dengan nomor ISSN 2829-1166.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 220 Documents
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Efektivitas Tanaman Sambiloto (Andrographis Paniculata) dan Senyawa Andrographolide dalam Menghambat Infeksi COVID-19 : Literature Review Shintia Christina; Kristin Natalia Meta Kali; Reni Angeline
Jurnal MedScientiae Vol. 1 No. 1 (2022): August
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscie.v1i1.2496

Abstract

Sambiloto (Andrographis paniculata) has long been used as a herbal medicine by local Indonesian people, especially because it is easy to find in the yard of the house. Since the onset of the COVID-19 pandemic, various handling efforts have been carried out, ranging from pharmacological and non-pharmacological. Various herbal plants that have the potential to be used as COVID-19 treatments have begun to be tested, including A. paniculata. To find out the benefits and mechanisms of A. paniculata in the treatment of COVID-19, a literature review study was conducted by tracing data in the form of scientific journals published in the last 2 years since the pandemic began. At the end of the results of this study, A. paniculata demonstrated its function in inhibiting COVID-19 through the mechanism of preventing virus attachment to surface receptors and inhibiting viral replication.
Faktor Risiko yang Behubungan dengan Swamedikasi Demam pada Anak di Desa Lubuk Empelas Kecamatan Muara Enim, Privinsi Sumatera Selatan Fedora Jolie Jolie; Djap Hadi Susanto
Jurnal MedScientiae Vol. 1 No. 1 (2022): August
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscie.v1i1.2505

Abstract

Self-medication is a community action in overcoming symptoms of the disease by using over-the-counter drugs without going to a doctor. Self-medication by the community is generally obtained from generation to generation from previous experience. Symptoms of illness that are treated, generally are fever. The study aims to determine the factors associated with self-medication for fever in children. The research method used is a cross-sectional approach, data were collected using a questionnaire obtained by interviewing and filling out a questionnaire. Subjects are children aged 1-12 years, questionnaire to the child’s mother. Data were analyzed using univariate and bivariate. Results: The proportion of fever self-medication behavior was 69%. The average education level of high school graduates, and family income is below the regional minimum wage. The majority of children were in the range of 5-9 years. Self-medicated by their mothers with fever due to common illnesses such as colds. There was a relationship between the mother's level of knowledge (p = 0.000), information sources (p = 0.044), and the number of children (p = 0.027) with fever self-medication behavior in their children.
Hubungan Tingkat Stres dengan Tekanan Darah Menjelang Ujian OSCE pada Mahasiswa Fakultas Kedokteran UKRIDA Ainullah Nurrahmah; Anna Maria Dewajanti; Winarsi Rudiharso
Jurnal MedScientiae Vol. 2 No. 1 (2023): April
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v2i1.2506

Abstract

The Objective Structured Clinacal Examination (OSCE) is one of the clinical competency assessment method that has been tested and widely used especially in the field of medical education. The aim of this research is to find out the relationship between stress levels and blood pressure ahead of the OSCE exam for students of UKRIDA medical faculty. This research used cross sectional Study. Sampling in this study using total sampling technique is the whole of the population to be researched using questionnaires. To determine the relationship variables, this research used the statistical test Chi Square. The total sample obtained was 66 samples. The results of this study indicate that students aged 22 years experience more stress than older people and stress is more common in women than men. The level of stress experienced by students before the OSCE is a normal stress level. The blood pressure experienced by students is optimal blood pressure. Based on statistical tests, it shows that there is a relationship between stress levels and blood pressure before OSCE in UKRIDA FK students with p value = 0.004
Penggunaan Antibiotik pada ISPA Gambaran Penggunaan Antibiotik pada Anak Dibawah Usia Lima Tahun (Balita) dengan Infeksi Saluran Pernapasan Akut (ISPA) di Puskesmas Kelurahan Tanjung Duren Selatan Tahun 2020-2021: Antibiotik pada ISPA Balita William William; Axel Thio Wijaya; Donna Mesina Pasaribu; Johannes Hudyono
Jurnal MedScientiae Vol. 1 No. 2 (2022): Desember
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscie.v1i2.2510

Abstract

Acute respiratory infections (ARI) is a disease that attacks the respiratory tract with various symptoms. The biggest cause of ARI is a virus (90-95%), so there is no need for antibiotics because most of the causes of ISP are viruses. Irrational administration of antibiotics can lead to bacterial resistance. The purpose of this study was to describe the use of antibiotics in infants under five years of age with ARI at the Tanjung Duren Selatan Village Health Center in the 2020-2021 period. This research was conducted by descriptive observational on 50 subjects. Sampling by consecutive sampling. The results of this study indicate that the majority of ARI patients have cough symptoms (96%) with an age range of 1-3 years (52%) and birth weight < 15 kg (92%). Complete basic immunization status is only 30%. Most of children under five with ARI (80%) did not get antibiotics and as many as 20% of patients under five with ARI used antibiotics, namely amoxicillin. This study concluded that according to the etiology of ARI in children under five caused by a virus, most of the Toddler patients with ARI  not receive antibiotics (80%) and Toddlers who used antibiotics (20%).
Posisi dan Lama Duduk saat Bekerja dalam Menimbulkan Low Back Pain Hartanto Hartanto; Budiman Hartono; Theodora Margaret
Jurnal MedScientiae Vol. 1 No. 1 (2022): August
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscie.v1i1.2541

Abstract

Low back pain (LBP) is a pain sensation in the L1-S1 region that can radiate to the legs and feet. Position and long time sitting while working are one of the factors that cause LBP. The purpose of this study was to determine the position and long time sitting while working in causing LBP. The method used in the literature study was done by searching in the research journal databases, namely Google Scholar and Pubmed. The results obtained 11 articles that meet the inclusion and exclusion criteria. Sitting upright and hunched over increase complaints of LBP, because it affects the amount of pressure exerted on the spine. This pressure will cause microtrauma accompanied by inflammation, causing LBP. Sitting duration that more than 4 hours is sufficient to cause LBP and the risk of LBP increases when sitting for a longer time, ie 6–9 hours and >9 hours. Sitting for long time will cause the muscles to become tired, reducing muscle support to the spine. This causes the pressure on the ligaments and intervertebral discs to increase. In this literature study also found other factors that can cause LBP, namely: age, chair back, working period and stretching.
The KARAKTERISTIK KLINIKOPATHOLOGI BERDASARKAN LOKASI KANKER KOLOREKTAL DI RUMAH SAKIT BETHESDA, YOGYAKARTA: - Elbert Hansyah Wibowo Wibowo
Jurnal MedScientiae Vol. 2 No. 2 (2023): August
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v2i2.2543

Abstract

Colorectal cancer has prevalence about 10% of all cancer that can cause death. Incident number of colorectal cancer in the US in 2021 about 104.270 colon cancer cases and 45.230 rectal cancer cases with death number was 52.980 lives. There were 1.544 patients diagnosed with colorectal cancer in RSUP Dr. Sarjito between year 2008-2017 among of them 820 male and 724 female.  This research used retrospective descriptive using medical record data of colorectal cancer patients between year 2016-2020, and data were analyzed using univariat and were displayed in the form of tabel and diagram. This research  used research variables, including: location of colorectal cancer, stage, age, gender, histopathological picture, and clinical symptoms. Colorectal cancer There were a total of 60 patients with details of right colorectal cancer patients being male (5 patients), moderate age range (4 patients), stages 3 and 4 (2 patients each), histopathological type of adenocarcinoma (4 patients), and symptoms clinical abdominal pain (4 patients).  The most common colorectal cancer is left colorectal cancer, with male gender, 40-64 years old, histopathological type of adenocarcinoma, and stage 4.
Hubungan Usia dengan Benign Prostate Hyperplasia dan Adenokarsinoma Prostat di Rumah Sakit Bethesda Yogyakarta Jennifer Isabel Roberth; Jonathan Willy Siagian; Tejo Jayadi; Hariatmoko
Jurnal MedScientiae Vol. 1 No. 2 (2022): Desember
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscie.v1i2.2549

Abstract

Age is a risk factor for the occurrence of Benign Prostate Hyperplasia (BPH) and prostate adenocarcinoma. The prevalence of BPH increases as the size of the prostate gland itself increases in older men. Prostate adenocarcinoma is the most common type of prostate cancer. In 2020, the incidence of prostate cancer is fifth in the male sex. Older men show an increased incidence of BPH and prostate adenocarcinoma compared to younger men. This study was conducted to determine the relationship between age with BPH and prostate adenocarcinoma in Bethesda Hospital Yogyakarta. The design of this study was cross-sectional using 62 medical records belonging to Bethesda Hospital Yogyakarta in 2015-2019 which were taken using the consecutive sampling method. Data were analyzed using Fisher Exact Test and obtained p value=0.048 (p<0.05). The results of this study indicate there is a relationship between age and BPH and prostate adenocarcinoma.
Pengaruh Pemberian Probiotik pada Infeksi Clostridium Difficile Ade Dharmawan; Dhimas Garin Dewa Agista; Sinsanta Sinsanta; Nicolas Layanto; Deby Deby
Jurnal MedScientiae Vol. 1 No. 2 (2022): Desember
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscie.v1i2.2567

Abstract

Clostridium difficile (C. difficile) is a gram-positive, anaerobic, spore-forming bacterium, and is an important pathogen in antibiotic-associated diarrhea. These bacteria are normal flora in the human digestive tract but can become pathogenic and form toxins consisting of 2, namely toxin A and toxin B. Due to antibiotics including risk factors for C. difficile infection (CDI), the treatment that can be given is probiotics. Probiotics may be effective in the prevention and treatment of CDI in several ways: alteration of gut flora, enhancement of antimicrobial activity, and as immunomodulators. The effect of probiotics, the method of administration, and the varying duration of administration make probiotics unable to be used as a therapy for C. difficile infection. However, probiotics can still be an option for adjuvant therapy in the treatment of CDI.
Hubungan Indeks Massa Tubuh dengan Kejadian Kanker Prostat dan Gleason Score di Rumah Sakit Siloam Kupang Valerio Christopher Homalessy; Shintia Christina; Erma Mexcorry Sumbayak
Jurnal MedScientiae Vol. 1 No. 1 (2022): August
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscie.v1i1.2571

Abstract

Prostate cancer can be termed as the most commonly diagnosed cancer in men. The risk of prostate cancer increases with age. Knowing whether there is a relationship between Body Mass Index (BMI) with prostate cancer and gleason score at Siloam Hospital Kupang. Methods, qualitative research method with cross sectional design and using secondary data from medical records with consecutive sampling technique. Results, patients diagnosed with prostate cancer at Siloam Hospital for the 2017-2021 period were 80 cases and 60 cases were not prostate cancer. The BMI in the group of prostate cancer patients was 54 people (67.5%) in the non-obese group and 34 people (56.67%) in non-prostate cancer. The most cases of prostate cancer with histopathological degrees of High Gleason Score were 45 cases (56.25%), and histopathological degrees of Low Grade Score were 35 cases (43.75). The chi square analysis, it is known that there is no relationship between BMI and the incidence of prostate cancer having a p value = 0.189 (p > 0.05) and the Gleason Score has a p value = 0.764 (p > 0.05). Conclusion there was no relationship between BMI and the incidence of prostate cancer and gleason score at Siloam Hospital Kupang.
Interferon Gamma sebagai Deteksi Awal Infeksi yang Disebabkan oleh Toxoplasma gondii Monica Puspa Sari
Jurnal MedScientiae Vol. 1 No. 1 (2022): August
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscie.v1i1.2572

Abstract

Early diagnosis of Toxoplasma gondii infection is crucial for the efficacy of the treatment. The medicine only kill tachyzoite form but not in bradyzoite form that can be found in the cyst. As we know, the shorter the time that we use to detect the infection, the greater the chance of the treatment to success. However, a diagnostic method, the antibody-based serological tests, often is used to detect T. Gondii but have some limitations. Based on recent research, a test known as Interferon-gamma release assay (IGRA), was introduced to detect T. gondii infection. The test was based on T cellin vitro assays and can detect both acute and chronic infections. IGRA can detect the infection as early as day 3, while IgM and IgG serum can be detected on day 9 and 13 post-infection. IGRA accurately distinguish between infected and non infected individuals by showing an activation of lymphocytes after being stimulated via in vitro by T. gondii antigens, even on the first day of life. IGRA is an easy and inexpensivemethod to measure cell mediated immunity to T. gondii. Therefore, IGRA has the potential to be a diagnostic tool for the early detection of T.gondii infection.

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