cover
Contact Name
Rina Priastini Susilowati
Contact Email
rina.susilowati@ukrida.ac.id
Phone
+6285311980272
Journal Mail Official
medscientiae.jurnal@ukrida.ac.id
Editorial Address
Gedung A Lantai 1, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Kristen Krida Wacana Jl. Arjuna Utara No. 6, Duri Kepa, Kebon Jeruk, Jakarta Barat, Jakarta 11510
Location
Kota adm. jakarta barat,
Dki jakarta
INDONESIA
Jurnal MedScientiae
ISSN : -     EISSN : 28291166     DOI : https://doi.org/10.36452/jmedscientiae
Core Subject : Health, Science,
Jurnal MedScientiae adalah jurnal yang dikelola oleh Fakultas Kedokteran dan Ilmu Kesehatan Universitas Kristen Krida Wacana. Jurnal ini mempublikasikan artikel-artikel secara open access dalam lingkup bidang kedokteran dan kesehatan seperti kedokteran dasar, bioetika kedokteran, biologi sel, biologi molekuler, genetika, fisiologi, biokimia, bioinformatika, anatomi, farmakologi, kesehatan masyarakat, dan ilmu biomedik lainnya. Tim editorial menerima naskah berupa artikel penelitian, literature dan systematic review, dan laporan kasus. Naskah yang dikirimkan hendaknya belum pernah diterbitkan sebelumnya di jurnal maupun media yang lain dan disiapkan sesuai dengan template atau format yang telah ditentukan. Setiap naskah yang memenuhi kriteria jurnal akan direview oleh pakar yang sesuai (peer reviewer). Jurnal MedScientiae tidak mengenakan biaya selama proses mulai dari penerimaan naskah hingga publikasi. Jurnal MedScientiae terbit 3 kali dalam satu tahun, yaitu pada bulan April, Agustus dan Desember dengan cakupan keilmuan yang telah disebutkan di atas. Edisi pertama jurnal akan diterbikan di bulan Mei tahun 2022 dengan nomor ISSN 2829-1166.
Articles 257 Documents
The Role of Vitamin D in Viral Infection Arsita, Elli; Laksana, Prasetya Agung; Darmawan, Guntur
Jurnal MedScientiae Vol. 5 No. 1 (2026): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v5i1.4035

Abstract

Vitamin D deficiency occurs in almost 50% of the population worldwide. The role of vitamin D in the immune system can be seen in both innate and adaptive immunity. Coronavirus Disease 2019 or COVID-19 is a new type of disease that has never been previously identified by humans. Many efforts have been made to prevent the spread of COVID-19 such as consumption of vitamin D3. This literature review aims to determine the role of vitamin D3 in COVID-19 infection. Based on a literature review of 10 studies with primary data, this literature review shows that patients with vitamin D deficiency accompanied by COVID-19 infection have higher CRP levels, clinical severity, and mortality rates. The endocrine society recommends a daily dose of Vitamin D3 supplementation in the range of 1500-2000 IU/day for adolescent adults. The administration of a single high dose of vitamin D (200,000 IU) has been shown to be ineffective in accelerating the hospitalization of COVID-19 patients in hospitals. It can be concluded that low vitamin D levels are associated with high CRP. It has been proven that Vitamin D3 plays a role in reducing mortality, preventing cytokine storms, and preventing long COVID-19 because the dose, daily requirement, comorbidities, and vitamin D deficiency are different for each individual.
Studi Komparatif Antara Magnesium Sulfate-Nifedipine dan Isoxsuprine-Nifedipine dalam Manajemen Persalinan Prematur Antonius, Antonius; Sondakh, Ivan Maurits; Siagian, Ruthsuyata
Jurnal MedScientiae Vol. 5 No. 1 (2026): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v5i1.4101

Abstract

Preterm labor, defined as the onset of labor before 37 weeks of gestation, is a leading cause of neonatal morbidity and mortality. Effective management strategies are essential to delay delivery and improve neonatal outcomes. This study aims to compare the effectiveness and safety of Magnesium Sulfate-Nifedipine and Isoxsuprine-Nifedipine in managing preterm labor, focusing on success rates of tocolysis, maternal and neonatal outcomes, and associated side effects. A prospective randomized trial was conducted at Tangerang City General Hospital, involving 64 pregnant women with preterm labor. Participants were divided into two groups: Group 1 (Magnesium Sulfate-Nifedipine) and Group 2 (Isoxsuprine-Nifedipine), with 32 patients in each. Magnesium Sulfate-Nifedipine showed a significantly higher success rate of tocolysis (93.75%) compared to Isoxsuprine-Nifedipine (81.25%; p=0.002). In cases with cervical dilatation >1 cm, success rates were 90.0% for Group 1 and 44.4% for Group 2 (p=0.033). Similarly, for effacement >25%, success rates were 85.7% for Group 1 versus 16.7% for Group 2 (p=0.009). None showed cardiovascular side effects such as tachycardia or hypotension. Magnesium Sulfate-Nifedipine shows superior efficacy in treating preterm labor, especially in patients with advanced cervical changes. Both regimens were safe, with minimal side effects.
Perbandingan Proporsi Hipertensi pada Pasien DMT2 Obesitas dan Non Obesitas di RS UKRIDA Massie, Naomi; Dharmawan, Guntur; Winaktu, Gracia JMT
Jurnal MedScientiae Vol. 5 No. 1 (2026): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v5i1.4181

Abstract

Type 2 diabetes mellitus (T2DM) is a major global health burden with rising prevalence and complications, including hypertension as a key comorbidity that increases cardiovascular risk in both obese and non-obese patients. This study aimed to analyze differences in hypertension proportions between obese and non-obese T2DM patients at UKRIDA Hospital from January 2022 to May 2025 and to describe variations by age and gender. Using a comparative analytical cross-sectional design and total sampling, the study included 348 eligible patients. Data were analyzed using the Pearson Chi-square test, revealing a significant association between nutritional status and hypertension (p = 0.024; OR = 1.656; φ = 0.121). Obese T2DM patients were 1.6 times more likely to develop hypertension than non-obese ones, though the relationship was weak. Hypertension prevalence was similar across age (<65 and ≥65 years) and gender groups. In conclusion, hypertension was common in both obese and non-obese T2DM patients, suggesting that factors beyond obesity contribute to elevated blood pressure in this population.
Clinical Risk Factors Associated with Kidney Stones in Adult Patients at Tarakan Regional General Hospital Putri, Mega Indira Rajan; Kumar, Bhanu; Pandapotan, Roy Akur; Arsita, Elli
Jurnal MedScientiae Vol. 5 No. 1 (2026): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v5i1.4203

Abstract

Kidney stones are a common health probem that can cause various complications. Various clinical factors are thought to play a role in the occurrence of kidney stones, particularly metabolic conditions and urinary tract disorders. This study aims to analyze the relationship between diabetes mellitus, hypertension, obesity, urinary tract infections, and urinary tract obstruction with the occurrence of kidney stones in adult patients. This study is an analytical observational study with a cross-sectional design using medical record data of adult patients at Tarakan Central Hospital in Central Jakarta. Data analysis was performed univariately, bivariately using the Chi-Square test, and multivariately using binary logistic regression. The results of the analysis showed that hypertension and diabetes mellitus were significantly associated with the occurrence of kidney stones. Hypertension was the most dominant factor with an odds ratio (OR) of 3.924 (95% CI: 1.249–12.330), while diabetes mellitus had an OR of 3.860 (95% CI: 1.259–11.850). Obesity and urinary tract infection did not show a statistically significant association. It can be concluded that hypertension and diabetes mellitus are risk factors associated with kidney stones in adult patients, with hypertension being the dominant factor.
Analisis Pengaruh Jenis Air Terhadap Pembusukan Daging Sapi Untuk Memperkirakan Waktu Kematian Seseorang Irab, Imelda Margaretha; Yen, Liauw Djai; Hartono, Budiman; Antoni, Marcel
Jurnal MedScientiae Vol. 5 No. 1 (2026): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v5i1.4208

Abstract

Decomposition is a natural process that occurs as soon as the physiological functions of the body cease, at a rate that is influenced by the condition of the body and the environment in which it is located.  This study is a descriptive experimental study with a cross-sectional approach that aims to describe the effect of different types of water media, namely fresh water, brackish water, and sea water, on the process of beef spoilage. Air media was used as a comparison control group. The results showed that beef spoilage took place fastest in brackish water media, followed by fresh water, sea water, and slowest in closed air media. Decomposition in closed air media is inhibited due to low humidity, which triggers desiccation and natural mummification. The remaining connective tissue underwent slower decomposition due to the structural stability of collagen which is more resistant to enzymatic degradation. Different types of media significantly affected the rate of beef spoilage, in the order of fastest in brackish water, followed by freshwater, seawater, and slowest in closed air. This finding shows that the old rule of thumb does not always apply, because the rate of spoilage is more determined by environmental characteristics, especially salinity, pH, and water activity that affect the process of autolysis and tissue degradation.  
KARAKTERISTIK PASIEN PENYAKIT GINJAL KRONIK DI RUMAH SAKIT TARAKAN JAKARTA PADA TAHUN 2025 Djaja, Tobias; Kumar, Bhanu; Winaktu, Gracia JMT
Jurnal MedScientiae Vol. 5 No. 1 (2026): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v5i1.4239

Abstract

Chronic Kidney Disease (CKD) is a growing global health problem, and understanding patient characteristics is essential for improving clinical management. This descriptive study analyzed 131 medical records of CKD patients at Tarakan General Hospital in 2025. Most patients were male (54.2%), with the largest age group being 60–70 years (29.8%) and the most common occupation being homemakers (32.1%). CKD stage 5 was the most prevalent (84.4%), and 67.2% of these patients underwent hemodialysis. The most common risk factor was hypertension (68.7%), followed by cardiovascular disease (51.1%) and diabetes mellitus (46.6%). The majority of patients had anemia (78.6%; mean hemoglobin 9.2 g/dL), normal potassium levels (55.7%), and low bicarbonate levels (66.4%). These findings provide a comprehensive overview of CKD patient characteristics at Tarakan General Hospital and can serve as a basis for improving clinical care and guiding future research.
Menjembatani Teori dan Praktik: Tinjauan Naratif Early Clinical Exposure dalam Pendidikan Kedokteran Tahap Pre-Klinik Josephine, Jodie
Jurnal MedScientiae Vol. 5 No. 1 (2026): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v5i1.4250

Abstract

Early Clinical Exposure (ECE) has become an essential component of integrated medical curricula, aiming to bridge the long-standing divide between basic science teaching and clinical practice. This narrative review synthesised fourteen studies published in the past five years to examine the educational rationale, implementation models, and outcomes of ECE for undergraduate medical students. Evidence shows that ECE enhances integration of basic and clinical sciences, strengthens motivation, and supports early professional identity formation. Students also gain confidence and foundational clinical skills when ECE includes structured supervision and opportunities for guided practice. Different implementation models, hospital-based, classroom-integrated, community-based, and hybrid, offer distinct benefits aligned with specific learning mechanisms. However, substantial variability in programme design, supervision quality, and learning environments contributes to inconsistent outcomes. Common barriers include large cohort sizes, limited clinician availability, overcrowded clinical settings, and reliance on brief or observational exposure. These issues highlight a persistent gap between the strong theoretical foundations of ECE and its uneven practical execution. Optimising ECE requires intentional, longitudinal design; structured reflection; adequately prepared supervisors; and alignment with experiential, social, and contextual learning principles. When effectively implemented, ECE can serve as a transformative element of early medical training.