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Journal of Clinical Pharmacy and Pharmaceutical Science
Published by Politeknik Katolik Mangunwijaya
ISSN : 28293452     EISSN : 28293460     DOI : 10.61740
Core Subject : Health,
Medicine & Pharmacology
spek ilmu Farmasi Sains dan Klinis meliputi: Ilmu Farmasi, Farmasi-Biologi, Farmasi-Kimia, Farmasi-Fisika, Farmakognosi, Mikrobiologi Farmasi,
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 42 Documents
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Pengaruh Edukasi Dengan Audio Visual Terhadap Pengetahuan Ibu Tentang Stunting Desa Teluti Baru Tahun 2023 Maritje S.J Malisngorar; Ety Dusra; Siti Nadya Silawane
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 4 No. 2 (2025): Oktober : Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v2i2.45

Abstract

Stunting is a condition of growth failure that occurs in children under five years of age (bavi under five years) as a result of chronic malnutrition so that children look short at their age. Stunting occurs in the critical period from the womb, 1000 HPK to the age of two years. if not addressed it will have a permanent impact because stunting is irreversible or cannot be corrected. This study is to determine the effect of education with audio visual media on mothers' knowledge about stunting in Telutih Baru Village, Tehoru District.This study used Pre-Experiment method with one group pre-test and post-test design. The population in this study were 45 mothers who had a 2-year-old bailta. While the sample in this research is 45 mothers who have toddlers aged 2 years in Teluti Baru Village, Tehoru District. The sampling technique used total sampling technique The research instrument used a questionnaire in the form of statements, the variable in this study was a single variable, namely maternal knowledge. The analysis used in this study was the Wilcoxon Test.analysis of the effect of education with Audio Visual media on maternal knowledge about stunting in Teluti Baru Village, Tehoru District in 2023 from the results of the Wilcoxon Test Respondents' knowledge decreased 0, knowledge remained 0, Respondents' knowledge increased 45.
Faktor-Faktor Yang Mempengaruhi Kesehatan Reproduksi Pada Remaja SMP Di Wilayah Kerja Puskesmas Tanjung Unggat Kota Tanjungpinang Kepulauan Riau Redayanti Redayanti; Sri Muharni; Rachmawaty M.Noer
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 4 No. 2 (2025): Oktober : Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v2i2.47

Abstract

The biggest problem faced by teenagers in Indonesia is adolescent reproductive health problems, including unwanted pregnancy (UTD), abortion, early marriage and marriage, STDs or STDs and HIV/AIDS (Marmi et al, 2020). The aim of this research is to determine the factors that influence reproductive health in junior high school adolescents in the Tanjung Unggat Community Health Center working area. This type of research is quantitative descriptive with a cross sectional approach. The sampling method in this research is total sampling or saturated sampling. The sample in this study consisted of 83 junior high school teenagers. Data collection methods and tools use questionnaires. The conclusion from the data analysis is that there is a relationship between knowledge and family support and reproductive health in junior high school adolescents in the Tanjung Unggat Community Health Center Working Area, Tanjungpinang City with a significant p value = 0.000 <0.05. Suggestions for health workers to provide education about adolescent reproductive health, so that adolescents avoid problems related to adolescent reproductive health.
Identifikasi Senyawa Tanin Dan Evaluasi Ekstrak Kulit Alpukat Persea Americana Mill Sebagai Lotion Silfi Arini Durri; Muhammad Walid
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 3 No. 1 (2024): April : Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v3i1.49

Abstract

Avocado is a fruit that is rich in vitamin content including vitamin A, vitamin B, vitamin C and also vitamin E which can be beneficial for body health and can be used as a cosmetic to maintain skin moisture. Therefore, in this study, lotion will be made from avocado fruit extract. The purpose of this research was carried out in an experimental way. Extraction was carried out by maceration method using 96% ethanol then lotion preparation formulation test was carried out and to determine the stability of physical quality, then organoleptic test, homogeneity test, pH test, spreadability test and phytochemical screening and tannin test were carried out. The results showed that avocado skin extract contains tannin compounds using 3 different reagents, using fecl3 reagent produces a blackish green color then with gelatin reagent produces a white precipitate and the last with pb acetate reagent produces a white endapat so from these 3 reagents it can be concluded that it positively contains tannins. In the lotion dosage formulation, the evaluation results consist of organoleptical tests, the results obtained in replicates 1 to 3 have no difference in terms of shape, color, and odor, homogeneity test results obtained in replicates 1 to 3 obtained homogeneous dosage forms, ph test results obtained in replicates 1 to 3 obtained an average result of ±7.0, irritation test results obtained in respondents 1 to 5 the results are not irritating to the skin and the spreadability test results obtained in replicates 1 to 3 obtained an average result of ±7.63 from all evaluations there are still
Pengembangan Metode Identifikasi Sianida Pada Bahan Pangan Fransiska Ayuningtyas Widyastani; Gerda Erina Ayu Widyastuti; Endang Hariyani; Fransisca Probo Setyoningrum
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 4 No. 1 (2025): April : Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v3i1.50

Abstract

Cyanide (CN-) is a compound that is commonly found in food and can cause health problems and reduce the bioavailability of nutrients in the body and even death, so the presence of cyanide needs to be controlled.Ninhydrin functions as a cyanide complexing reagent formed from the oxidation of thiocyanate which can be used to identify the presence of cyanide. This study aims to develop a cyanide identification method using the ninhydrin cyanide test kit. The test kit is a tool that can be used to detect levels of a compound quite accurately which is easy to use and operate by various groups. The reaction of ninhydrin with cyanide forms hydrindantine which will give a red color to the strip containing Na2CO3. This study uses a qualitative method with the type of pre-experimental research. The results of the data obtained were analyzed using a descriptive test that uses a pie chart frequency so that the results for cassava were positive at 93.3%, while the results were negative at 6.67%. So from this research it can be concluded that the development of a cyanide examination method using the Ninhydrin Test Kit method can be used to identify samples that are suspected to contain free cyanide qualitatively.
Gambaran Penggunaan Obat Golongan Narkotika dan Psikotropika di Rumah Sakit X Indra Mukti; Rita Septiana; Khotimatul Khusna
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 3 No. 2 (2024): Oktober : Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v3i2.55

Abstract

Narcotics and Psychotropics were substances that were managed with strict laws by the government. Based on a survey by the National Narcotics Agency (BNN) and the Indonesian Institute of Sciences (LIPI), 2.3 million students in Indonesia have consumed narcotics. This study aims to see the types of narcotic and psychotropic drugs given to outpatients at Hospital X, Sragen Regency. This study was a descriptive study, research data was taken from outpatient medical records. The sample in this study were outpatients aged 18-60 years, receiving narcotic and oral psychotropic drugs with complete medical record data. The results of the study showed that most of the patients were female at 75%, the largest age group in the range of >25-45 years at 47%, the most common diagnosis was coronary heart disease at 81%, and the most common main complaint was muscle pain and cramps at 50%. The type of narcotic drugs given to patients at hospital x in Sragen district was codeine at 19%, while the types of psychotropic drugs that were often given were opineuron 46%, analsik 27% and alprazolam 8%. For further researchers, it is necessary to evaluate the use of narcotic and psychotropic drugs.
Analisis Deskriptif Ketepatan Penggunaan Antihipertensi di Salah Satu Puskesmas di Kabupaten Boyolali Arvita Sari; Rita Septiana; Risma Sakti Pambudi
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 3 No. 2 (2024): Oktober : Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v3i2.56

Abstract

The Silent Killer was a nickname for hypertension. Hypertension was a dangerous disease that can attack anyone even without any complaints. Providing appropriate therapy can guarantee the success of therapy for hypertensive patients. This study aims to determine the percentage of correct drugs, correct indications, correct doses and correct patients regarding the administration of antihypertensive drugs at one of the Community Health Centers in Boyolali for the period January-June 2021. This was a type of retrospective descriptive research, with 106 samples taken from medical record data. The results of the study showed that 69.81% of hypertensive patients were female, 30.19% of patients were aged ≥65 years, 90.57% had no comorbidities and 74.53% were diagnosed with grade 1 hypertension. The antihypertensives given to the patients were adequate. The criteria for correct indication were 100%, correct patient was 96.23%, correct drug was 81.13% and correct dose was 93.40%.
Penetapan Kadar Cemaran Logam Kadmium (Cd) dalam Jamu Pegal Linu Sediaan Serbuk Secara ICP-OES Najla Putri Adelaida; Ruth Elenora Kristanty; Ai Emalia Sukmawati; Siti Nur Aliza Fauziah
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 3 No. 2 (2024): Oktober : Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v3i2.51

Abstract

One aspect of safety that needs attention in traditional medicine is the presence of heavy metal contamination. Heavy metal contamination, specifically cadmium (Cd), can occur in herbal products. The presence of cadmium in herbal medicines is highly dangerous to humans due to its toxic nature, which can cause health problems such as bone fragility and breathlessness. Testing is limited to checking the labeling of the herbal medicine logo and determining the level of cadmium contamination in powdered formulations of herbal medicines using Inductively Coupled Plasma – Optical Emission Spectrometry (ICP-OES). The testing aims to determine whether the samples of powdered herbal medicine for joint pain meet the labeling requirements according to the Decree of the Head of the Indonesian Food and Drug Administration No. HK.00.05.4.2411 of 2004 and comply with the cadmium contamination level requirements according to the Regulation of the Indonesian National Agency of Drug and Food Control No. 29 of 2023. The herbal medicine logo on the samples meets the requirements. The cadmium content in the powdered herbal medicine samples is 0.184 mg/kg, which is below the requirement of 0.3 mg/kg. Therefore, it can be concluded that the samples Meet the Requirements (MS).
Penetapan Kadar Cemaran Logam Kadmium dalam Jamu Liver Sediaan Kapsul Secara Inductively Coupled Plasma–Optical Emission Spectrometry Lusi Veronika; Ruth Elenora Kristanty; Ai Emalia Sukmawati; Siti Nur Aliza Fauziah
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 3 No. 2 (2024): Oktober : Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v3i2.53

Abstract

Heavy metal contamination can cause health problems such as impaired brain, liver, kidney, lung and muscle function. One of the quality and safety checks for herbal medicine is heavy metal contamination analysis. Natural medicines can be contaminated from agriculture, production and distribution processes. Therefore, the test was carried out to determine the level of cadmium metal contamination in liver herbs in capsule preparations by Inductively Coupled Plasma - Optical Emission Spectrometry. The test aims to determine whether the capsule herbal liver samples meet the requirements for cadmium heavy metal levels in accordance with the Regulation of the Food and Drug Administration of the Republic of Indonesia Number 29 of 2023. This test uses samples of liver herbal medicine in capsule dosage form. The results of heavy metal contamination results were positive for cadmium with an average level of 0.4031 mg/kg. So it can be concluded that the sample does not meet the requirements (TMS) cadmium metal contamination levels.
Narrative Review of Anti-Retrovirals Used in COVID-19 Treatment Aditya Sindu Sakti; Irma Susanti; Djati Wulan Kusumo
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 3 No. 2 (2024): Oktober : Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v3i2.54

Abstract

The COVID-19 pandemic has necessitated the exploration of various therapeutic strategies, including the repurposing of existing antiviral drugs. This narrative review examines the use of anti-retroviral agents in the treatment of COVID-19, focusing on their mechanisms of action, efficacy, and safety profiles. Key antiretrovirals discussed include Remdesivir, Lopinavir/Ritonavir, Ribavirin, Oseltamivir, Favipiravir, and Sofosbuvir. These agents primarily act by inhibiting RNA-dependent RNA polymerase (RdRp), a critical enzyme in the replication cycle of SARS-CoV-2. Clinical trials and in vitro studies have provided mixed results regarding their effectiveness, with some agents showing promise in reducing mortality and improving recovery times, while others have demonstrated limited efficacy. The review highlights the urgent need for further clinical research to optimize antiviral regimens and improve patient outcomes in the ongoing battle against COVID-19.
Uji Aktivitas Antibakteri Fraksi Ekstrak Daun Jotang (Sphagneticola trilobata L) terhadap Bakteri Eschericia coli Ghalib Syukrillah Syahputra; Ibnu Rusyd; Arie Vonikartika; Zahara Zahara; Eka Febriyanti; Delladari Mayefis
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 4 No. 1 (2025): Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v4i1.58

Abstract

Jotang (Sphagneticola trilobata) is a wild plant that has antibacterial potential. This study aims to determine the antibacterial activity of the n-hexane, ethyl acetate and methanol fractions of jotang leaf extract against Escherichia coli bacteria. Jotang leaves were extracted using methanol by maceration extraction method, followed by the fractionation stage using Liquid-Liquid Extraction method. The fractionation process uses n-hexane, ethyl acetate and methanol as solvents. Next step, each fraction was tested for antibacterial activity using the disc diffusion method. The concentrations of each fraction used were 200 µg/disc, 400 µg/disc, and 1000 µg/disc, positive control used chloramphenicol and negative control used DMSO 10%. The Result showed the most potential antibacterial activity of the active fraction from jotang leaves extract was the n-hexane fraction.

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