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INDONESIA
Jurnal Sains Farmasi dan Kesehatan
Published by CV ITTC Indonesia
ISSN : -     EISSN : 30249368     DOI : 10.47233/jfkes
Core Subject : Health, Science,
Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary
Jurnal Sains Farmasi dan Kesehatan (JFKES) E-ISSN : 3024-9368 is an open access journal which is a media of research publication and review article on all aspects of pharmaceutical science that is innovative, creative, original and based on scientific. Articles published in this journal include Pharmaceutical Technology, Pharmacology, Pharmaceutical Chemistry, Traditional Medicine, Food and beverages, and the field of public health
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 164 Documents
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Literatur Review : Toksikologi Industri Dan Keselamatan Kesehatan Kerja Dalam Pengendalian Paparan Bahan Kimia Pada Sektor Manufaktur Dan Rumah Sakit: Indonesia Mardiah Sitorus; Rezki Alya Mawaddah Sitorus; Selamat Ariady Tampubolon; Abdurrozzaq Hasibuan
Jurnal Sains Farmasi Dan Kesehatan Vol. 3 No. 3 (2026): Januari - April
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v3i3.4451

Abstract

Industrial toxicology is a branch of science that plays a crucial role in identifying, analyzing, and controlling the impact of chemical exposure on worker health, particularly in the manufacturing and hospital sectors, which have high risk levels. Exposure to chemicals such as organic solvents, heavy metals, disinfectants, and cytotoxic drugs can cause both acute and chronic health problems if not managed properly. This study aims to examine the role of industrial toxicology in controlling chemical exposure and the application of Occupational Safety and Health (OHS) principles to minimize worker health risks. The method used is a literature review by analyzing various national and international journals from the last five years that are relevant to the research topic. The results of the study indicate that effective control of chemical exposure must refer to the hierarchy of control, including elimination, substitution, engineering, administrative control, and the use of personal protective equipment (PPE). In addition, the implementation of a structured OHS management system, continuous worker training, and routine monitoring of the work environment have been proven to reduce exposure levels and the risk of occupational diseases. These findings confirm that the integration of industrial toxicology with a comprehensive OHS system is not merely a formality, but a fundamental necessity for creating a safe, healthy, and productive work environment. Without disciplined controls, long-term risks to workers will continue to be overlooked, leading to a decline in the quality of human resources.
Pengaruh Terapi Spiritual Murottal Pada Klien Risiko Perilaku Kekerasan Di Rsj Prof. Dr. Hb Saanin Padang Tahun 2025 Wahyuni Muna Aprilia; Edo Gusdiansyah; Amelia Susanti
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4498

Abstract

The risk of violent behavior is a common psychiatric nursing problem in schizophrenia patients. At Prof. Dr. HB Saanin Mental Hospital in Padang, this prevalence remains high despite patients receiving general therapy, including physical, pharmacological, verbal, and spiritual therapy. An initial survey of ten patients showed that most still experienced physical and emotional symptoms, such as flushing, tense expressions, and verbal outbursts of anger. This suggests the need for additional spiritual interventions, one of which is Quranic recitation therapy. This study aims to determine the effect of spiritual recitation therapy on reducing the risk of violent behavior. This study used a quantitative approach with a pre-experimental design of one group pretest-posttest. The study sample consisted of 30 patients diagnosed with a risk of violent behavior who were treated in the Merpati and Flamboyan Wards of Prof. Dr. HB Saanin Mental Hospital, Padang. The sampling technique used purposive sampling according to the inclusion and exclusion criteria. Data collection was carried out using the RUFA observation sheet and analyzed using the parametric paired t-test. The results of the study showed that the average score of signs and symptoms in patients at risk of violent behavior before being given murottal therapy was 11.83 where the average respondent was in the intensive II category (moderate) while after therapy it increased to 18.40 where the average respondent was in the intensive II category (moderate). The results of the paired t-test showed a p value = 0.000, which means there was a significant influence between before and after murottal spiritual therapy on reducing symptoms of violence in patients. The conclusion of this study is that murottal spiritual therapy is effective in reducing signs and symptoms in patients at risk of violent behavior. Therefore, it is recommended that psychiatric nurses integrate murottal spiritual therapy as an intervention modality in psychiatric nursing practice to accompany generalist therapy for optimal results.
Hubungan Pengetahuan Remaja Dengan Kemampuan Remaja Menjaga Kebersihan Saat Menstruasi Pada Siswi Di Sekolah Menengah Pertama (Smp) Negeri 21 Kota Bengkulu Gita Lestari
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4519

Abstract

Menstruation is a physiological process experienced by every adolescent girl, yet many still lack knowledge and skills in maintaining hygiene during menstruation. This lack of knowledge can impact hygienic behavior and pose a risk of reproductive health problems. The research problem is the continued lack of skills in maintaining menstrual hygiene among female students. The purpose of this study was to determine the relationship between adolescent knowledge and the ability to maintain menstrual hygiene among female students at Junior High School 21 in Bengkulu City. This study used a descriptive analytical design with a cross-sectional approach. Sampling was conducted using total sampling, with 82 respondents. Data analysis used the Chi-square test with continuity correction. Of the 82 respondents, 27 (32.9%) had poor knowledge, and 55 (67.1%) had good knowledge. Thirty-two respondents (39.0%) had poor skills, while 50 respondents (61.0%) had good skills. The chi-square test results showed a p-value of 0.000 (p < 0.05), indicating a significant relationship between adolescents' knowledge and their ability to maintain menstrual hygiene. Suggestions include ongoing reproductive health education programs in schools through the School Health Unit (UKS) and regular counseling, as well as parental support in providing information and guiding menstrual hygiene behaviors at home.
Hubungan Perawatan Payudara Dengan Kejadian Bendungan Asi Pada Ibu Post Partum Di Puskesmas Sukamerindu Kota Bengkulu Teguh Anggraini
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4523

Abstract

The postpartum period is a critical period for breastfeeding mothers during the lactation process. One common problem is breast engorgement, which can disrupt the comfort and smoothness of breastfeeding. Suboptimal breast care is a risk factor for breast engorgement. The research problem is the persistence of postpartum mothers experiencing breast engorgement at the Sukamerindu Community Health Center in Bengkulu City. This study aims to determine the relationship between breast care and breast engorgement among postpartum mothers at the Sukamerindu Community Health Center in Bengkulu City. The research method used a quantitative analytical design with a cross-sectional approach. The sampling technique was purposive sampling, with a sample size of 74 participants. Data were analyzed using univariate and bivariate statistical methods using the chi-square test. The results showed that almost half (45.9%) reported poor breast care practices, and almost the majority (41.9%) experienced breast engorgement among postpartum mothers at the Sukamerindu Community Health Center in Bengkulu City (p-value 0.044). Suggestions to community health centers to continue providing education on correct breast care techniques need to be improved so that mothers can breastfeed comfortably and prevent lactation complications.
Asuhan Keperawatan Pada Pasien Dengan Tuberkulosis Paru (TB Paru) di Ruangan Muzdalifah Rumah Sakit Aisyiyah Pariaman Monica Angriana Putri; Kheniva Diah Anggita; Aulia Asman; Mike Asmaria
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4541

Abstract

Pulmonary tuberculosis can cause respiratory problems, significant weight loss, weakness, and even permanent reduction in lung capacity, even death. Pulmonary tuberculosis is the 10th leading cause of death in the world, with Indonesia being the second largest contributor (1.09 million cases) to the total tuberculosis burden. This disease remains a significant health problem, marked by the high incidence rate in various regions, one of which is at Aisyiyah Hospital Pariaman with the highest incidence rate in 2024 of 104 cases. This study aims to understand and provide nursing care to patients with pulmonary tuberculosis. The research method used is a case study conducted by means of observation, interviews, physical examinations and documentation studies, and nursing care was carried out in the Muzdalifah Room, Aisyiyah Hospital, Pariaman City, from February 24, 2026 to February 28, 2026, with 1 patient, namely Mrs. J. After 5 days of nursing care, six nursing problems were identified: ineffective airway clearance, hypovolemia, hyperthermia, nutritional deficits, unstable blood glucose levels, and the risk of infection. Implementation included airway management, effective coughing exercises, hypovolemia management, hyperthermia management, nutritional management, hyperglycemia management, and infection prevention. The results showed an improvement in the patient's health after receiving nursing care. Future efforts to improve education, treatment monitoring, and cross-sectoral collaboration are needed to effectively eradicate pulmonary tuberculosis.
Artikel Review : Pengaruh Penyalutan Terhadap Karakteristik Fisikokimia Tablet Salut Gula atau Enterik Nisful Lailatun Nadiroh; Dwi Roisiyah; Salsabiila Wina Delia; Najwa Firida Rahma; Adela Gerlani Bria; Rusdiana Tri Septiarini; Jihan Fahiroh Nur Arifin; Dewi Rahmawati; Yani Ambari; Dzakiya Zhihrotul Wida
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4596

Abstract

Tablet coating is one of the pharmaceutical technologies that plays an important role in improving the physicochemical characteristics and stability of tablet preparations. This study aims to comprehensively review the effect of coating processes on the physicochemical characteristics and stability of tablets, including mechanical properties, dissolution profiles, and active substance stability during storage. The method used is a literature review of 8 scientific journals obtained from Google Scholar, PubMed, PerpusNas, and ResearchGate databases, published within the last 5–10 years. The results showed that the coating process significantly affected physicochemical characteristics including hardness, friability, disintegration time, dissolution profile, and drug release. In terms of stability, coating protected active substances from environmental influences such as humidity, oxidation, and gastric acid degradation. Among the types of coating studied, enteric coating proved to be the most effective method as it provided maximum protection for acid-sensitive drugs and specifically controlled drug release in the intestine, thereby positively impacting bioavailability and therapeutic efficacy. Sugar coating also contributed to improving physical properties and protecting tablets during storage and distribution. Therefore, selection of appropriate coating type and composition is a critical factor in producing quality, stable, and therapeutically effective tablet preparations.
Asuhan Keperawatan Medikal Bedah Pada Pasien Dengan Diabetes Mellitus Tipe II Di Ruangan Muzdalifah Rumah Sakit Aisyiyah Pariaman Luthfiyah Sukma Asri; Aulia Asman; Mike Asmaria; Kheniva Diah Anggita
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4657

Abstract

Unhealthy lifestyles can be seen from the lifestyle of people who tend to be modern, which can be seen from lifestyle, irregular eating patterns, fast food, smoking habits, alcohol consumption and other behaviors that can increase the number of people suffering from degenerative diseases. According to the World Health Organization (WHO), around 422 million people in the world suffer from diabetes. The increase in premature mortality rates by 3% between 2000–2019 and the high risk of complications such as kidney failure and blindness make diabetes a serious chronic disease. In Indonesia, the prevalence reached 10.06% (19.46 million people) and increased to 11.7% based on the 2023 SKI. In West Sumatra, the number of cases increased from 48,616 (2022) to 52,355 (2023/2024), making diabetes the second most common disease. Data at Aisyiyah Pariaman Hospital shows a significant increase in the number of diabetes cases from year to year. The purpose of this Scientific Paper is to provide Nursing Care for Patients with Type II Diabetes. The method used is a case study with 1 patient, this case study was conducted in the Muzdalifah Room of Aisyiyah Pariaman Hospital on January 28 - February 3, 2026, after the assessment, a nursing diagnosis emerged, namely: Instability of blood glucose levels, nutritional deficits, impaired skin/tissue integrity. The evaluation obtained during 5 days of nursing care for the patient was instability of blood glucose levels, nutritional deficits, impaired skin/tissue integrity resolved on the 5th day, and impaired sense of comfort resolved on the 4th day. It can be concluded that with good nursing care can improve the health status of patients. It is hoped that patients and families can care for, anticipate, and provide support in home care, are able to maintain a healthy lifestyle, especially diet, and can utilize the nearest health facilities, so that the patient's blood glucose levels are controlled and the family is protected from disease.
Literatur Review : Pengembangan Sediaan Suppositoria Dari Berbagai Ekstrak Nailah Mutiara Wahid; Jesika Diah Pitaloka; Ria Fitriyanti Putri; Rizka Tri Amanda Hidayat; Zahratul Humaidah; Alvan Andika Permadani; Dewi Rahmawati; Dzakiya Zhihrotulwida; M. Fithrul Mubarak
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4689

Abstract

Suppositories are one of the pharmaceutical dosage forms administered via the rectal or vaginal route and are considered an alternative drug delivery system for patients who cannot take oral medications. The development of herbal-based suppositories has increased due to their perceived safety, minimal side effects, and diverse pharmacological activities. This study aims to review the development of suppository dosage forms based on various plant extracts through a literature review method. The method used in this study is a literature review by collecting and analyzing ten scientific articles discussing the formulation and evaluation of suppositories derived from various plant extracts such as Aloe vera, Amaranthus spinosus, Piper betle, Garcinia mangostana, Areca catechu, Peperomia pellucida, senna, Cynodon dactylon, and Cassia fistula. The analyzed parameters include formulation methods, types of bases used, physical evaluation results, and pharmacological activities. The results show that the fusion (moulding) method is the most commonly used technique in suppository preparation. The bases used include cocoa butter (oleum cacao), polyethylene glycol (PEG), and glycerinated gelatin, each influencing the physical characteristics of the suppositories such as melting point, melting time, hardness, and weight uniformity. In addition, various plant extracts demonstrate different pharmacological activities, including anti-inflammatory, antifungal, antibacterial, laxative, and anthelmintic effects. In conclusion, the development of herbal-based suppositories has significant potential as an effective and innovative drug delivery system. However, further studies, particularly stability testing and clinical trials, are required to ensure their safety and therapeutic effectiveness.
Asuhan Keperawatan Medikal Bedah Pada Pasien Dengan Demam Thypoid Di Ruangan Muzdalifah Rumah Sakit Aisyiyah Pariaman Nina Lusyana; Aulia Asman; Kheniva Diah Anggita; Linda Marni
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4690

Abstract

Typhoid fever is said to be an acute infectious disease of the digestive system caused by the bacteria Salmonella Typhi and is a global infectious disease. According to the World Health Organization (WHO), approximately 11–20 million cases occur each year with a mortality rate of 128,000–161,000 people. In Indonesia, the prevalence of typhoid fever reaches 1.7% with a morbidity rate of around 500 per 100,000 people, and predominantly occurs in children aged 5–14 years. In West Sumatra Province, the incidence rate reaches 1.51% and in Pariaman City it is 1.6%. Data at Aisyiyah Pariaman Hospital shows that in 2025 there were 225. The purpose of this Scientific Paper is to provide Nursing Care to Patient Mr. B, With Typhoid Fever. The method used is a case study with 1 patient, this case study was conducted in the Muzdalifah Room of Aisyiyah Pariaman Hospital on January 28 - February 3, 2026, after the assessment, a nursing diagnosis emerged, namely: Hyperthermia, Risk of Nutritional Deficit, Constipation and Risk of Bleeding. The implementation carried out includes Hyperthermia Management, Nutritional Management, Constipation Management and Prevention of Bleeding. The evaluation obtained during 5 days of nursing care for the patient is that the Risk of nutritional deficit and constipation can be resolved on the 5th day, Hyperthermia and Risk of Bleeding can be resolved in 4 days. It is recommended to patients and families to maintain personal and environmental hygiene, consume hygienic food and drinks, and comply with treatment to prevent recurrence of typhoid fever.
Health Insurance in Developing Countries: A Comparative Analysis of Financing Models, Membership Coverage, and Implementation Challenges in Indonesia, Thailand, and India Rizki Maulida Putri; Muhammad Syifa’ul Qulub; Febrina Putri Khairani; Muhammad Noval Dani Irwan; Jihan Zafira Hakim
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4694

Abstract

Universal Health Coverage (UHC) is a key objective in the development of health systems, emphasizing access to quality healthcare services without imposing financial hardship on the population. Indonesia, Thailand, and India implement different health insurance financing models and therefore face diverse implementation challenges. This study aims to compare the financing models, membership coverage, and implementation challenges of the national health insurance systems in these three countries. The research employs a systematic literature review using a document analysis approach. The primary data were obtained from literature reviews, quantitative studies, policy analyses, systematic reviews, and policy reports. The findings indicate that Thailand adopts a tax-funded financing model through the Universal Coverage Scheme (UCS), which has successfully expanded access to healthcare services but continues to face challenges related to service capacity and quality. India has developed various public health insurance schemes; however, the fragmented nature of its system has limited financial protection, resulting in persistently high out-of-pocket expenditures. Meanwhile, Indonesia implements the National Health Insurance (JKN) program based on a social health insurance model supported by government subsidies and contribution-based financing. This approach has achieved broad population coverage despite ongoing challenges related to financial sustainability, contribution compliance among informal sector workers, and disparities in healthcare access across regions. The success of UHC depends not only on achieving high enrollment coverage but also on ensuring sustainable financing, equitable access, high-quality healthcare services, and effective financial protection. The experiences of Thailand, India, and Indonesia demonstrate that each financing model possesses distinct strengths and challenges that can provide valuable lessons for strengthening national health insurance systems. Universal Health Coverage (UHC) merupakan tujuan penting dalam pembangunan sistem kesehatan yang menekankan akses layanan kesehatan yang bermutu tanpa menimbulkan beban finansial bagi masyarakat. Indonesia, Thailand, dan India menerapkan model pembiayaan asuransi kesehatan yang berbeda sehingga menghadapi tantangan implementasi yang beragam. Penelitian ini bertujuan membandingkan model pembiayaan, cakupan kepesertaan, dan tantangan implementasi sistem asuransi kesehatan nasional di ketiga negara. Penelitian ini menggunakan metode systematic literature review dengan menggunakan pendekatan analisis dokumen. Data utama yang diperoleh berasal dari literature review, studi kuantitatif, policy analysis, systematic review, dan laporan kebijakan. Hasil kajian menunjukkan bahwa Thailand menerapkan pembiayaan berbasis pajak melalui Universal Coverage Scheme (UCS) yang mampu memperluas akses kesehatan, namun masih menghadapi kendala pada kapasitas dan kualitas pelayanan. India mengembangkan berbagai skema asuransi publik, tetapi sistem yang terfragmentasi menyebabkan perlindungan finansial belum optimal dan pengeluaran langsung masyarakat (out-of-pocket) masih tinggi. Sementara itu Indonesia mengimplementasikan Jaminan Kesehatan Nasional (JKN) dengan model asuransi sosial yang didukung subsidi pemerintah dan sistem iuran, sehingga berhasil mencapai cakupan kepesertaan yang luas meskipun masih menghadapi tantangan berupa keberlanjutan pembiayaan, kepatuhan pembayaran iuran sektor informal, serta ketimpangan akses layanan antar wilayah. Keberhasilan UHC tidak hanya ditentukan oleh tingginya cakupan kepesertaan, tetapi juga oleh keberlanjutan pembiayaan, pemerataan akses, kualitas pelayanan, dan perlindungan finansial yang efektif. Pengalaman Thailand, India, dan Indonesia menunjukkan bahwa setiap model memiliki kelebihan dan tantangan yang dapat menjadi pembelajaran dalam memperkuat sistem jaminan kesehatan nasional.

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