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The International Journal of Medical Science and Health Research
ISSN : 30481376     EISSN : 30481368     DOI : -
Core Subject : Health,
The International Journal of Medical Science and Health Research, published by International Medical Journal Corp. Ltd. is dedicated to providing physicians with the best research and important information in the world of medical research and science and to present the information in a format that is understandable and clinically useful. Committed to publishing multidisciplinary research that spans the entire spectrum of healthcare and medicine access, The American Journal of Medical Science and Health Research aims at an international audience of pharmacists, clinicians, medical ethicists, regulators, and researchers, providing an online forum for the rapid dissemination of recent research and perspectives in this area.
Articles 400 Documents
Effects of Melatonin Supplementation in Type 2 Diabetes Mellitus Setiawan Nathan, Daniel; Yumilia, Hoo
The International Journal of Medical Science and Health Research Vol. 1 No. 1 (2024)
Publisher : International Medical Journal Corp. Ltd

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Abstract

Background: Diabetes mellitus, a metabolic illness causing hyperglycemia, is primarily caused by insulin resistance. Melatonin, an indolamine, plays a role in the circadian cycle and affects hunger, fullness, and awareness. Melatonin treatment has shown positive effects on glycated hemoglobin, fasting plasma glucose, and insulin levels, but may increase insulin sensitivity and reduce fasting insulin levels. Methods: This systematic review focused on full-text English literature published between 2014 and 2024 using the PRISMA 2020 guidelines. Editorials and review pieces published in the same journal as the submission without a DOI were not accepted. The literature was compiled using PubMed, ScienceDirect, and SagePub, among other online venues. Result: Our study team initially collected more than 100,000 publications using reliable sources including Science Direct, PubMed, and SagePub. Just five publications were found to be directly related to our ongoing systematic examination after a rigorous three-level screening approach. Subsequently, a comprehensive analysis of the complete text was conducted, and additional scrutiny was given to these articles. To facilitate viewing, Table 1 gathers together the literature that was examined for this analysis. Conclusion: Melatonin, a hormone, can affect glycemic control, obesity control, and energy expenditure. It regulates insulin secretion and protects against reactive oxygen species and free radicals. However, high levels can negatively affect insulin sensitivity.
Association of Selenium and Thyroid Cancer: A Comprehensive Systematic Review Setiawan Nathan, Daniel; Yumilia, Hoo
The International Journal of Medical Science and Health Research Vol. 1 No. 1 (2024)
Publisher : International Medical Journal Corp. Ltd

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Abstract

Introduction: Selenium's historical journey from discovery to its role in human health underscores its complex relationship with disease, particularly thyroid cancer. While research suggests a potential link between low selenium levels and thyroid cancer risk, conflicting findings challenge our understanding of selenium's impact, warranting further investigation. This systematic review aims to unravel selenium's intricate interplay with thyroid cancer, navigating through its historical significance, physiological role, and recent epidemiological studies to offer insights into this complex relationship. Method: The researchers in this study followed the 2020 Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines to ensure that their work met the required standards. This was done to ensure the precision and reliability of the conclusions derived from the research. Result: Our search produced 18 results. After looking at the titles and summaries, we found 7 papers that fit our criteria. At first, we excluded several articles because they were written in review style, pilot study, and case reports. But after reading the full papers carefully, we included five papers in our final analysis. These papers included experimental study, cross-sectional study, prospective cohort, and case control. Conclusion: This systematic review explores the relationship between selenium and thyroid cancer, highlighting SBP1 as a potential therapeutic target based on experimental evidence. Clinical studies suggest lower serum selenium levels in females with papillary thyroid cancer, indicating a potential protective effect with higher selenium levels. While the development of a tumor-targeted drug delivery system shows promise for thyroid cancer treatment, a large prospective cohort study found no association between selenium intake and thyroid cancer risk, emphasizing the need for further research, particularly biomarker-based studies.
Association of Metabolic Syndrome and Risk or Development of Chronic Kidney Disease: A Comprehensive Systematic Review Setiawan Nathan, Daniel; Yumilia, Hoo
The International Journal of Medical Science and Health Research Vol. 1 No. 1 (2024)
Publisher : International Medical Journal Corp. Ltd

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Abstract

Background: Metabolic syndrome (MetS) encompasses a cluster of metabolic abnormalities including hypertension, hyperlipidemia, hyperuricemia, hyperglycemia, central obesity, and insulin resistance. MetS and chronic kidney disease (CKD) are intricately linked and can influence each other. This study aims to serve a comprehensive systematic review to evaluate the association of MetS and CKD in literatures of the last 10 years.   Methods: The review adhered to PRISMA 2020 standards and analyzed full-text English literature from 2014 to 2024. It excluded editorials, review papers from the same journal, and submissions lacking a DOI. Literature sources included PubMed, SagePub, SpringerLink, and Google Scholar. Result: A total of 488 articles were retrieved from online databases (PubMed, SagePub, SpringerLink and Google Scholar). After three rounds of screening, five articles directly relevant to the systematic review were selected for full-text reading and analysis. Conclusion: The discussion emphasizes the complex link between metabolic syndrome (MetS) and chronic kidney disease (CKD), driven by modern lifestyle habits causing metabolic overload. Kidneys are especially susceptible to MetS effects, but effective treatment strategies are lacking. Further research is needed to understand and address MetS-related kidney damage.
Risk Factor and Management of Peritonitis related to Peritoneal Dialysis in Low Income Countries Setiawan Nathan, Daniel; Sanjaya, Charles
The International Journal of Medical Science and Health Research Vol. 1 No. 1 (2024)
Publisher : International Medical Journal Corp. Ltd

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Abstract

Background: Peritoneal dyalisis (PD) may offer some advantages over hemodyalisis (HD) with regard to quality of life and kidney transplantation outcome and costs savings. Methods: This systematic review focused on full-text English literature published between 2014 and 2024 using the PRISMA 2020 guidelines. Editorials and review pieces published in the same journal as the submission without a DOI were not accepted. The literature was compiled using PubMed, ScienceDirect, and SagePub, among other online venues. Result: Five publications were found to be directly related to our ongoing systematic examination after a rigorous three-level screening approach. Subsequently, a comprehensive analysis of the complete text was conducted, and additional scrutiny was given to these articles. Conclusion: The technologies lead to a decrease in the peritonitis rates but effective training of the patient about catheter care and PD techniques still play an important role in the prevention of PD peritonitis.
Prevalence, Management, and Outcome of Lupus Nephritis: A Ten Years Systematic Review Setiawan Nathan, Daniel; Sanjaya, Charles
The International Journal of Medical Science and Health Research Vol. 1 No. 1 (2024)
Publisher : International Medical Journal Corp. Ltd

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Abstract

Background: Lupus nephritis (LN) occurs in ~50% of patients with SLE and is the most common, but not the only, cause of kidney injury in SLE. Men with SLE tend to have more aggressive disease with higher rates of renal and cardiovascular involvement and are more likely to develop kidney failure than women. Methods: This systematic review focused on full-text English literature published between 2014 and 2024 using the PRISMA 2020 guidelines. Editorials and review pieces published in the same journal as the submission without a DOI were not accepted. The literature was compiled using PubMed, ScienceDirect, and SagePub, among other online venues. Result: Five publications were found to be directly related to our ongoing systematic examination after a rigorous three-level screening approach. Subsequently, a comprehensive analysis of the complete text was conducted, and additional scrutiny was given to these articles. Conclusion: Achieving a complete clinical response to treatment is critical to preserving long-term kidney health.
Diagnostic Imaging of Thoracolumbar Spine Traumas: A Comprehensive Systematic Review Sugih Laksono, Bella; Fauzi Yazidah, Iklima
The International Journal of Medical Science and Health Research Vol. 1 No. 2 (2024)
Publisher : International Medical Journal Corp. Ltd

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Abstract

Background: Thoracolumbar (TL) fractures are among the most common spine injuries encountered in emergency trauma care with burst fractures accounting for 10% to 20% of all spinal fractures. Methods: This systematic review focused on full-text English literature published between 2014 and 2024 using the PRISMA 2020 guidelines. Editorials and review pieces published in the same journal as the submission without a DOI were not accepted. The literature was compiled using PubMed, ScienceDirect, and SagePub, among other online venues. Result: Five publications were found to be directly related to our ongoing systematic examination after a rigorous three-level screening approach. Subsequently, a comprehensive analysis of the complete text was conducted, and additional scrutiny was given to these articles. Conclusion: MRI is more sensitive than other imaging modalities in the diagnosis of soft tissue and spinal cord injuries.
The Effect of Complementary and Alternative Medicine for Treatment of Gliomas: A Comprehensive Systematic Review Putra, Yosie Yulanda; Lestari, Deby Tri; Auliya, Ahsan; Ananda, Astrid; Syarfina, Afdila; Azhari, Ririn; Merisa L, Bella
The International Journal of Medical Science and Health Research Vol. 1 No. 2 (2024)
Publisher : International Medical Journal Corp. Ltd

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Abstract

Background: Since the majority of GBM patients are aware that there is no known cure, it makes sense that they would want to know about complementary, alternative, and CIM therapies. Methods: This systematic review focused on full-text English literature published between 2014 and 2024 using the PRISMA 2020 guidelines. The literature was compiled using PubMed, ScienceDirect, and SagePub, among other online venues. Result: Five publications were found to be directly related to our ongoing systematic examination after a rigorous three-level screening approach. Conclusion: complementary and alternative medicine methods to comfor patients with gliomas with the medication side effects that taking control of the disease. The findings of this systematic review helped to educate the providers and patients to stimulate more research according to complementary and alternative medicine for treatment of gliomas.
Diagnostic Imaging Performance of Acute Cholecystitis: A Ten Years Systematic Review Laksono, Bella Sugih; Yazidah, Iklima Fauzi
The International Journal of Medical Science and Health Research Vol. 1 No. 2 (2024)
Publisher : International Medical Journal Corp. Ltd

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Abstract

Background: Acute cholecystitis is a common surgical emergency and ultrasound (US) is currently considered the first-line diagnostic imaging test. The relative accuracy of computed tomography (CT) in detecting acute cholecystitis has received little attention in the literature. Methods: This systematic review focused on full-text English literature published between 2014 and 2024 using the PRISMA 2020 guidelines. Editorials and review pieces published in the same journal as the submission without a DOI were not accepted. The literature was compiled using PubMed, ScienceDirect, and SagePub, among other online venues. Result: Five publications were found to be directly related to our ongoing systematic examination after a rigorous three-level screening approach. Subsequently, a comprehensive analysis of the complete text was conducted, and additional scrutiny was given to these articles. Conclusion: Ultrasound (US) is a good imaging modality for the diagnosis of acute cholecystitis with discriminative power.
Comparison of Efficacy and Outcome of Minimally Invasive versus Open Surgery for Intradural-Extramedullary Spine Tumors: Systematic Review Putra, Yosie Yulanda; Lestari, Deby Tri; Auliya, Ahsan; Ananda, Astrid; Syarfina, Afdila; Azhari, Ririn; Merisa L, Bella
The International Journal of Medical Science and Health Research Vol. 1 No. 2 (2024)
Publisher : International Medical Journal Corp. Ltd

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Abstract

Background:  While traditional wide-incision approaches pose risks of long-term spinal instability, minimally invasive techniques, increasingly favored since the late 1990s, require further investigation regarding their safety and efficacy compared to open approaches for Intradural extramedullar (ID-EM) tumor resection. Methods: This systematic review focused on full-text English literature published between 2014 and 2024 using the PRISMA 2020 guidelines. The literature was compiled using PubMed, ScienceDirect, and SagePub, among other online venues. Result: Employing a meticulous three-tier screening approach, we identified only five papers that were directly pertinent to our ongoing systematic assessment. Subsequently, we conducted a comprehensive examination of the entire text and further selected articles; retrospective study, retrospective analysis, retrospective observational study; comparative, prospective cohort, and retrospective cohort study. Conclusion: The minimally invasive transspinous approach demonstrates safety and efficacy comparable to open surgery, with reduced intraoperative blood loss, but further randomized studies are needed to assess their cost-effectiveness and wider adoption. Although minimally invasive tubular retractor surgery shows favorable outcomes, particularly in reducing postoperative paraspinal muscle fatty degeneration and analgesic consumption, larger studies are warranted to confirm its long-term effects on pain reduction and patient outcomes. As these techniques gain traction, their potential benefits in improving patient care will become increasingly apparent.
Diagnosis, Management, and Outcome of Stroke Infark: A Ten Years Systematic Review Halim, Stevanie S; Zaskia, Nanda Ayu
The International Journal of Medical Science and Health Research Vol. 1 No. 2 (2024)
Publisher : International Medical Journal Corp. Ltd

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Abstract

Background: Treatment for Ischemic stroke has shown promising results with antiplatelet therapy and ginkgo biloba extracts, but clopidogrel and aspirin resistance may increase bleeding risk. Ticagrelor, a novel antiplatelet drug, shows efficacy. Methods: Using the PRISMA 2020 principles, this systematic review concentrated on full-text English literature published between 2014 and 2024. Among other internet resources, PubMed, ScienceDirect, and SagePub were used to compile the literature. Result: Following a thorough three-level screening process, six publications were determined to be closely connected to our current comprehensive review. Following that, an extensive examination of the entire text was carried out, and these articles were subjected to further inspection. Conclusion: Antiplatelet therapy's efficacy and safety in treating ischemic stroke are limited due to short symptom onset, high price, and low accessibility. Combining antiplatelet therapy with rt-PA for better outcomes is recommended. Neuroprotective agents like ginkgo diterpene lactone meglumine show potential for improving functional outcomes and reducing bleeding risks.

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