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The International Journal of Medical Science and Health Research
Published by International Medical Journal Corp. Ltd.
ISSN : 30481376     EISSN : 30481368     DOI : -
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary
The International Journal of Medical Science and Health Research, published by International Medical Journal Corp. Ltd. is dedicated to providing physicians with the best research and important information in the world of medical research and science and to present the information in a format that is understandable and clinically useful. Committed to publishing multidisciplinary research that spans the entire spectrum of healthcare and medicine access, The American Journal of Medical Science and Health Research aims at an international audience of pharmacists, clinicians, medical ethicists, regulators, and researchers, providing an online forum for the rapid dissemination of recent research and perspectives in this area.
Arjuna Subject : Kedokteran - Review dan Referensi, Kedokteran
Articles 529 Documents
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The Analysis Study of Diagnostic Approaches in Acute Appendicitis: A Comprehensive Systematic Review Roni Andre Syahputra Damanik; Amran H Sinaga
The International Journal of Medical Science and Health Research Vol. 10 No. 6 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/tm5a2r26

Abstract

Background: Diagnostic approaches for appendicitis have evolved to improve accuracy and reduce negative appendectomy rates. Laboratory markers and imaging modalities have been developed to provide supportive but non-specific information. However, challenges persist in balancing accuracy with concerns like radiation exposure and cost-effectiveness. This systematic review seeks to synthesize existing evidence on diagnostic approaches in acute appendicitis, examining their performance, limitations, and potential for standardized integration into clinical practice. Methods: This systematic review was conducted in accordance with the PRISMA 2020 guidelines, incorporating only full-text, peer-reviewed articles published in English from 2015 to 2025. To maintain the integrity and reliability of the sources, editorial pieces and review articles lacking a Digital Object Identifier (DOI) were excluded. A comprehensive literature search was performed using databases such as ScienceDirect, PubMed, and SAGE Publications to identify relevant studies. Result: An initial search of selected databases identified over 300 potentially relevant studies. After a structured three-phase screening process, only eight met the inclusion criteria for detailed review. These articles underwent rigorous critical appraisal to evaluate their relevance and quality. This ensured that the final analysis was based on strong evidence aligned with the study’s objectives. Conclusion: The effective diagnosis and management of acute appendicitis necessitate an integrated approach involving clinical scoring systems, imaging studies, and evidence-based surgical decision-making. Imaging is crucial for confirmation and planning, while timely surgical intervention is essential. Advancements in diagnostic tools and surgical techniques can improve patient outcomes and reduce healthcare burden.
The Analysis Study of Diagnostic Imaging Performance and Accuracy of Tuberculosis: A Systematic Review Shani Abidi; Handri Andika
The International Journal of Medical Science and Health Research Vol. 10 No. 6 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/bgatf972

Abstract

Background: Tuberculosis (TB) remains a major global health challenge, with its variable clinical presentations often complicating timely and accurate diagnosis. Diagnostic imaging modalities such as chest X-ray, computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography/computed tomography (PET/CT) provide varying degrees of sensitivity and specificity depending on disease location and progression. However, diagnostic accuracy may be influenced by interobserver variability, regional disease prevalence, and coexisting conditions. This systematic review aims to critically evaluate and compare the diagnostic performance and accuracy of various imaging techniques in TB to support evidence-based clinical decision-making. Methods: This review adhered strictly to the PRISMA 2020 guidelines, incorporating only full-text, peer-reviewed articles published in English between 2015 and 2025. To ensure the credibility and traceability of sources, editorial pieces and review articles lacking a Digital Object Identifier (DOI) were excluded. A comprehensive search strategy was implemented across three major academic databases—ScienceDirect, PubMed, and SAGE Publications—to identify studies directly relevant to the research objectives. Result: The initial database search yielded over 100 potentially relevant studies. Through a structured three-phase screening and selection process, eight studies fulfilled the predefined inclusion criteria and were selected for detailed analysis. These studies were rigorously appraised for methodological quality and relevance, ensuring that the final synthesis was based on robust and high-quality evidence. The findings provide critical insight into the strengths and limitations of each imaging modality in the context of TB diagnosis. Conclusion: Diagnostic imaging is a cornerstone in the evaluation of tuberculosis, with each modality offering distinct advantages depending on the clinical scenario. CT thorax demonstrates the highest accuracy for detecting pulmonary TB, while MRI is superior for assessing extrapulmonary manifestations, particularly in the central nervous system and spine. Ultrasonography (USG) serves as a valuable adjunct in evaluating abdominal and pleural involvement. A tailored, context-specific imaging strategy is essential to enhance diagnostic precision and optimize patient management.
The Analysis Study of Efficacy of Pediatric Emergency Care Protocol: A Comprehensive Systematic Review Muhamad Taufan Kurniawan; Mega Rizkina; Dyah Nur Chasanah
The International Journal of Medical Science and Health Research Vol. 11 No. 1 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/dz4rke94

Abstract

Background: Pediatric emergencies require unique protocols to manage critically ill or injured children. Pediatric Emergency Care Protocols (PECPs) aim to standardize assessment, triage, and intervention processes, reducing variability and improving patient outcomes. However, adherence and efficacy vary across healthcare settings, particularly in low-resource environments. A systematic review is crucial for evaluating protocols' effectiveness and adaptability. Methods: This systematic review followed PRISMA 2020 guidelines and included only full-text, peer-reviewed articles published in English between 2015 and 2025. Editorials and review papers without a DOI were excluded to ensure source quality. Relevant studies were identified through targeted searches in ScienceDirect, PubMed, and SAGE Publications. Result: An initial search across selected databases produced more than 100 potentially relevant studies. Through a structured three-phase screening process, only eight articles satisfied the predetermined inclusion criteria for detailed examination. These selected studies were subjected to rigorous critical appraisal to assess their contribution to understanding the effectiveness of pediatric emergency care protocols. This systematic approach ensured that the final analysis was based on robust evidence aligned with the study’s objectives and capable of yielding meaningful insights into this complex area. Conclusion: The Pediatric Emergency Care Protocol is a crucial tool in pediatric emergency medicine, ensuring rapid identification and management of life-threatening conditions in children. Its comprehensive disease coverage aligns with international standards, despite challenges like training gaps and limited technology access.
The Analysis Study of Comparative Effectiveness of Different Therapies for Hyperthyroidism: A Comprehensive Systematic Review Luthfiyya Syafiqa Tahany; Sinarty Hartanto
The International Journal of Medical Science and Health Research Vol. 11 No. 1 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/x12tpb19

Abstract

Background: Hyperthyroidism is a condition characterized by excessive thyroid hormone production, which can lead to serious health complications if not properly managed. Available treatments—antithyroid drugs, radioactive iodine therapy, and thyroidectomy—vary in efficacy, safety, and appropriateness depending on individual patient factors. This review aims to systematically assess and compare these therapies to guide evidence-based clinical decision-making. Methods: This review followed PRISMA 2020 requirements and included only peer-reviewed, full-text English papers from 2015 to 2025.  Editorials and review papers lacking DOIs were eliminated to ensure source dependability and citation tracking.  To find articles that fit the review's study topic, PubMed, ScienceDirect, and SAGE Publications were extensively searched. Result: The initial database search identified more than 2,000 potentially relevant studies.  Eight studies met the predefined inclusion criteria and were selected for detailed analysis through a structured three-phase screening and selection process.  The studies underwent thorough evaluation for methodological quality and relevance, guaranteeing that the final synthesis relied on strong and high-quality evidence.  The findings offer essential insights into the strengths and limitations of the comparative effectiveness of various therapies for hyperthyroidism. Conclusion: The effectiveness of hyperthyroidism treatments depends on individual patient factors, clinical conditions, and treatment goals. Antithyroid drugs are suitable for initial therapy, while radioactive iodine and surgery provide more definitive outcomes, each with distinct risks and benefits. This review highlights the importance of personalized, evidence-based approaches to optimize treatment selection and enhance patient care..
Effectiveness of Dual Antiplatelet Therapy (DAPT) to Reduce Stroke Recurrence in Patients with Minor Stroke or High Risk Transient Ischemic Attach (TIA): A Comprehensive Systematic Review Jeremy Jovanie Owen Tobing; Eka Pranata
The International Journal of Medical Science and Health Research Vol. 11 No. 1 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/52smrk12

Abstract

Background Patients who experience a minor stroke or a high-risk transient ischemic attack (TIA) are at an increased risk of stroke recurrence. Effective secondary prevention strategies are critical to reducing the burden of stroke-related morbidity and mortality. This systematic review aims to evaluate the effectiveness of DAPT in reducing stroke recurrence in patients with minor stroke or high-risk TIA. Methods: The study followed PRISMA 2020 guidelines, reviewing English-language publications from 2015 to 2025. Editorials, duplicate reviews from the same journal, and papers lacking a DOI were excluded. The literature search was conducted using PubMed, SagePub, SpringerLink, and Google Scholar. Result: A total of 1.800 articles were initially identified through online databases (PubMed, SagePub, SpringerLink, and Google Scholar). After three rounds of screening, eight relevant studies were selected for full-text analysis. Conclusion:    DAPT is a superior strategy compared to SAPT in reducing stroke recurrence in patients with minor stroke or high-risk TIA. However, its safety concerns, particularly regarding major bleeding, necessitate careful patient selection and treatment duration optimization. Current data suggest that a 21-day DAPT regimen followed by SAPT offers the best balance of efficacy and safety, particularly in patients with atherosclerotic stroke. Future studies should continue refining treatment approaches to maximize the benefits of DAPT while minimizing risks.
Influenza Vaccine in Children with Cancer Undergoing Chemotherapy Grace Erdiana; Edi Setiawan Tehuteru
The International Journal of Medical Science and Health Research Vol. 12 No. 1 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/eab64w29

Abstract

Influenza is a respiratory tract infection caused by a virus that primarily affects children, especially those under 5 years old. Influenza symptoms are generally mild but can worsen in certain conditions such as in immunocompromised patients, including those with cancer. Cancer patients undergoing chemotherapy experience immune system defects, resulting in an inadequate response to infections. It has been reported that children with cancer who contract influenza have longer hospital stays and are at risk of developing pneumonia and respiratory failure. Administration of the influenza vaccine is the most effective prevention to avoid infection and complications from influenza. The inactivated influenza vaccine has been proven safe and can be given to cancer patients undergoing chemotherapy. The challenge in vaccine administration is convincing parents to continue vaccinating their children with cancer.
Analysis Study of Geriatric Syndrome and Frailty Prevalence in Older Adults: A Systematic Review and Meta-Analysis Pretika Prameswari; Yudhi Hajianto Nugroho; Mutia Juliana
The International Journal of Medical Science and Health Research Vol. 12 No. 1 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/swz60349

Abstract

Background: Geriatric syndromes and frailty are major public health concerns associated with adverse health outcomes in aging populations worldwide. Frailty is a multifactorial condition characterized by increased vulnerability to stressors, leading to higher risks of morbidity, functional decline, hospitalization, and mortality. Objective: This meta-analysis aims to evaluate the prevalence, risk factors, and outcomes of frailty in older adults, as well as the effectiveness of various interventions in mitigating its impact. Methods: A systematic literature search was conducted across major databases to identify studies assessing frailty and geriatric syndromes. Studies were screened based on predefined eligibility criteria, and data were extracted for pooled analysis. Results: The findings indicate that frailty prevalence varies widely across different populations and is strongly associated with advanced age, comorbidities, malnutrition, and sedentary lifestyles. The pooled odds ratio for frailty versus robustness was 0.17 (95% CI: 0.16–0.18, p < 0.00001), indicating a strong negative association, with frail individuals being significantly more vulnerable to adverse health outcomes. However, substantial heterogeneity was observed across studies (I² = 100%), likely due to variations in frailty assessment tools, study populations, and geographic settings. Frailty prevalence ranged from 9.4% in rural Malaysia to 47.1% in Botswana, reflecting socioeconomic and healthcare disparities. Common risk factors included advanced age, female gender, chronic diseases, physical inactivity, and malnutrition. Conclusion: Addressing geriatric syndromes and frailty requires a holistic, multidisciplinary approach integrating early detection, prevention, and individualized interventions. Public health strategies and policy reforms should prioritize frailty screening, community-based support, and interdisciplinary care coordination to enhance the well-being of older adults and alleviate the burden on healthcare systems. Future research should focus on optimizing frailty management strategies and evaluating long-term outcomes in diverse populations.
Effectiveness of Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Patients With End-Stage Renal Disease Arta Pebrina; Agus Harsoyo
The International Journal of Medical Science and Health Research Vol. 12 No. 1 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/njppp262

Abstract

Introduction: Coronary artery disease (CAD) is highly prevalent in patients with end-stage renal disease (ESRD), posing significant treatment challenges. Percutaneous Coronary Intervention (PCI) and Coronary Artery Bypass Grafting (CABG) are the main revascularization strategies, but their comparative effectiveness and safety in ESRD patients remain unclear. Methods: A comprehensive review of 13 studies, including randomized controlled trials, observational cohorts, and meta-analyses, was conducted. Studies were selected based on adult ESRD populations comparing PCI and CABG outcomes, focusing on mortality, major adverse cardiac events (MACE), repeat revascularization, quality of life, and complications. Results: Short-term mortality was consistently lower with PCI (e.g., 1.2% vs. 15.4% at 30 days in Wang et al., 2020). Acute renal failure incidence was also lower after PCI (2.3%) compared to CABG (7.7%) in CKD patients (Giustino et al., 2018). Long-term outcomes, including all-cause mortality and MACE, were generally comparable between PCI and CABG across multiple studies. However, in patients with diabetes and CKD, CABG showed superior 10-year survival (44.2% vs. 64.3% mortality; Gao et al., 2020). Repeat revascularization rates were often higher after PCI, though some studies reported similar complete revascularization success. Quality of life improvements were noted with PCI in early CKD stages but not in advanced stages. Discussion: PCI offers a safer short-term profile with fewer complications, while CABG may provide better long-term survival in select high-risk subgroups. Differences in complication profiles and patient comorbidities should guide treatment choice. Conclusion: Treatment decisions for ESRD patients with CAD should be individualized, balancing short-term safety and long-term benefits, ideally within a multidisciplinary framework.
The Efficacy of Radiofrequency in Tonsillectomy Procedures: A Comprehensive Systematic Review Anika Istika; Revy Octarian Palmendha
The International Journal of Medical Science and Health Research Vol. 12 No. 2 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/r5am7272

Abstract

Background: Tonsillectomy, a common surgical procedure, has seen advancements in radiofrequency (RF) technology, aiming to improve postoperative outcomes by reducing intraoperative bleeding, postoperative pain, and recovery time. However, the efficacy of RF in tonsillectomy remains a topic of ongoing research, requiring further evaluation for optimal patient care. Methods: This systematic review adhered to PRISMA 2020 principles and focused exclusively on full-text papers published in English between 2015 and 2025.   Editorials and review articles without a DOI were omitted to preserve the integrity of high-quality sources.   A literature review was conducted utilizing esteemed databases like ScienceDirect, PubMed, and SagePub to discover relevant studies. Result: The preliminary database search yielded over 500 relevant publications on the topic. Following a comprehensive three-stage screening process, eight papers met the specified inclusion criteria and were selected for in-depth analysis. Each study underwent a comprehensive critical assessment, enabling a thorough understanding of the efficacy of radiofrequency in tonsillectomy procedures. This methodical method guaranteed that the analysis relied on high-quality evidence, corresponded with the study's aims, and was capable of producing substantial insights into this intricate relationship. Conclusion: Radiofrequency tonsillectomy is a surgical technique that enhances postoperative comfort, reduces risks, and supports faster return to normal activity. However, long-term outcomes and recurrence rates require further exploration. Standardized protocols for radiofrequency tonsillectomy are essential for improving patient outcomes and redefining otolaryngologic surgery standards.
The Prognostic Value of Global Longitudinal Strain (GLS) in Predicting Outcomes in Coronary Artery Disease Jason Wirandy Haryanto; Kevin Jonatan Sandi; Clement Panduwinata; Nathaniel Hiwandika
The International Journal of Medical Science and Health Research Vol. 12 No. 2 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/k835wn64

Abstract

Introduction: Coronary artery disease (CAD) is a leading cause of morbidity and mortality worldwide. Global Longitudinal Strain (GLS) has emerged as a promising echocardiographic parameter for assessing left ventricular function and predicting clinical outcomes in CAD patients. Methods: The study followed PRISMA 2020 guidelines, reviewing English-language publications from 2015 to 2025. Editorials, duplicate reviews from the same journal, and papers lacking a DOI were excluded. The literature search was conducted using PubMed, SagePub, Semanthic Scholar, and Google Scholar. A systematic review of recent literature was conducted, focusing on studies that evaluated the prognostic value of GLS in CAD. Data were extracted regarding GLS measurements, clinical outcomes, and risk stratification. Results: The findings indicate that impaired GLS is significantly associated with adverse outcomes, including myocardial infarction, heart failure, and increased mortality. GLS provides incremental prognostic information beyond traditional measures such as left ventricular ejection fraction (LVEF), enhancing risk stratification in CAD patients. Discussion: GLS serves as a sensitive marker for detecting subclinical myocardial dysfunction, allowing for earlier intervention strategies. Its ability to predict adverse events underscores its potential role in routine clinical practice for managing CAD. Conclusion: GLS is a valuable tool in the assessment of cardiac function and risk stratification in patients with CAD. Incorporating GLS into clinical practice may improve patient outcomes through timely identification of high-risk individuals.

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