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Svāsthya: Trends in General Medicine and Public Health
Published by PT Mega Science Indonesia
ISSN : -     EISSN : 30630649     DOI : https://doi.org/10.70347/svsthya
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Svāsthya: Trends in General Medicine and Public Health is a multidisciplinary journal and it is published six times (January, March, May, July, September, and November) a year. The objective is to promote articles on general medicine, infection, public health, Global health Infection, Tropical diseases, One health and eco-epidemiology, Biomedical sciences, Epidemiology and clinical epidemiology, Molecular biology, Biology of disease and infection, Environmental health, Epidemiology and biostatistics, Disease, prevention and health promotion, Health technology and innovation, Microbiology, Pharmacological medicine, Traditional medicine, and Diseases in tropics. Svāsthya publishes original research work across all disciplines of medicine and allied sciences, related to infection, public health, global health, tropical infection, one health and diseases in tropics. The journal publishes original articles, short report, case report, review articles, systematic review - meta analysis and letters to the editor. All articles published in Svāsthya are peer-reviewed and published online for immediate access and citation.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 6 Documents
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Search results for , issue "Vol. 2 No. 6 (2025): November 2025" : 6 Documents clear
Dose-dependent effects of cholecalciferol supplementation on hepatocyte ballooning in Sprague–Dawley rats Veonika, Dea Anenta
Svāsthya: Trends in General Medicine and Public Health Vol. 2 No. 6 (2025): November 2025
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v2i6.134

Abstract

Obesity is an accumulation of fat body condition due to calories and energy imbalance. Low vitamin D levels are also associated with lower HDL levels, increased triglyceride levels, and increased triglyceride deposition levels in hepatocytes and liver parenchyma. Vitamin D supplementation has various benefits for obesity, such as by improving lipid profiles, reducing BMI, reducing waist circumference, and reducing hip circumference. This study aims to analyze the histopathological changes in the liver of male rats induced by a high-fat, high-fructose diet and supplemented with cholecalciferol. Thirty male Sprague-Dawley rats aged 6-8 weeks were randomly allocated into 5 groups. The normal control (KN) group only received the BR-2 pellet and PAM ad libitum. The negative control (K-) group received a high-fat, high-fructose diet (HFHF) for 28 days. The P1 group received only HFHS for the first 28 days and was supplemented with cholecalciferol 2500 IU thereafter. The P2 group received only HFHF for the first 28 days and was supplemented with cholecalciferol 5000 IU thereafter. The P3 group received only HFHF for the first 28 days and was supplemented with cholecalciferol 10000 IU thereafter. Histopathological analysis involves analyzing the microscopic image of the liver tissue of the obese rat models after receiving treatment with cholecalciferol for 56 days. After 8 weeks of intervention, cholecalciferol supplementation resulted in different findings on histopathological analysis. After intervention with cholecalciferol, there is no significant difference in the degree of steatosis and lobular inflammation on rat liver histopathology (p>0.05). Cholecalciferol supplementation resulted in a significant difference in hepatocyte ballooning on liver histopathology (p<0.05).  Administration of cholecalciferol at doses of 2,500 IU, 5,000 IU, and 10,000 IU was not significant in improving liver steatosis and lobular inflammation, but could reduce the occurrence of liver ballooning
Validity and reliability of the knowledge and attitude assessment tool for cadres in tsunami-prone areas Ekaputri, Kintan Resqitha; Faizatiwahida, Novia; Andini, Febri Tri; Oktaria, Rina; Mukhlis, Zikri; Nasution, Riska Amalya; Sari, Putri Irwanti
Svāsthya: Trends in General Medicine and Public Health Vol. 2 No. 6 (2025): November 2025
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v2i6.150

Abstract

Padang city is a high-risk area for tsunamis, making the presence of disaster preparedness cadres crucial as the frontline in response. However, many cadres have never received formal training and have limited knowledge and attitudes regarding tsunami emergencies. Cadre competency evaluation has been hampered by the lack of specific, psychometrically tested instruments. This study aimed to test the validity and reliability of tsunami preparedness knowledge and attitudes instruments for cadres in tsunami-prone areas.  This cross-sectional study included 90 respondents. The instrument was developed through a literature review and a qualitative study. Content validity was tested through expert assessment via three expert judgments. The construct validity and reliability were tested on 90 cadres. Instrument validity was assessed via biserial correlation (knowledge) and Pearson’s product‒moment correlation (attitude). Reliability was tested via the Kuder Richardson formula (KR-20) and Cronbach's alpha. The results of the expert judgments on the knowledge and attitude questionnaires were 0.81–1 and 0.75–1, respectively. The construct validity test resulted in 12 knowledge statement items and 12 attitude items that were declared valid, with R values > R values. The reliability test results for the knowledge and attitude questionnaires were 0.630 and 0.737, respectively, indicating that the questionnaire is reliable. This instrument can be used by health workers, community nurses, and policymakers to map cadre capacity accurately and as an evaluation tool before and after providing future disaster training
An overview of hazard identification and risk assessment in industrial safety (2015–2025): A narrative review Aini, Nur; Berliana, Ratih; Badriyah, Lailatul
Svāsthya: Trends in General Medicine and Public Health Vol. 2 No. 6 (2025): November 2025
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v2i6.154

Abstract

Hazard identification and risk assessment (HIRA) is a key element in occupational health and safety (OHS) and industrial safety systems, particularly in high-risk industrial sectors with complex processes and dynamic operations. Over the past decade, various methodological developments have been proposed, but their application remains scattered and not optimally integrated. This narrative review aims to synthesize and critically examine research findings related to the application of HIRA and risk assessment methods in the context of occupational and industrial safety and health. This study employed a narrative-review approach. A structured literature search was conducted through the ScienceDirect database for articles published between 2015 and 2025 via a combination of keywords related to hazard identification, risk assessment, occupational safety, and the industrial context. From the 2,093 publications obtained in the initial stage, a multistep screening process was conducted based on relevance, inclusion criteria, full-text evaluation, and conceptual assessment, ultimately yielding 15 core articles for the qualitative synthesis. The synthesis results revealed that the methodological depth of HIRA implementation significantly impacts the quality of OHS decision-making support. Hybrid methods (e.g., fuzzy Bayesian networks integrated with HFACS) demonstrated 15–30% higher accuracy in hazard prioritization than standalone qualitative matrices did. The effectiveness of the method is highly dependent on the system complexity, hazard characteristics, and maturity level of the organization. This narrative review demonstrates a paradigm shift from HIRA as an administrative obligation to HIRA as a strategic, risk-based tool to support OHS decision-making. An adaptive, integrated, and decision-oriented risk assessment approach provides a stronger foundation for developing an effective and sustainable safety management system.
Inhibitory effect of an ethanol extract of sembung leaves (Blumea balsamifera) on the growth of Helicobacter pylori: In vitro approach Ariastuti, Indria; Suardana, Anak Agung Komang; Wahyudi, I Wayan
Svāsthya: Trends in General Medicine and Public Health Vol. 2 No. 6 (2025): November 2025
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v2i6.156

Abstract

Helicobacter pylori infection is a global health problem with a high prevalence in developing countries and plays a role in the pathogenesis of various gastrointestinal disorders. Antibiotic resistance is a major challenge in the eradication of H. pylori, prompting the exploration of alternative antibacterial agents derived from traditional medicinal plants. To analyze the antibacterial activity of an ethanol extract of sembung leaves (Blumea balsamifera) against Helicobacter pylori growth in vitro. This experimental study used a posttest control group design with five concentrations of the ethanol extract of sembung leaves (10%, 20%, 40%, 60%, and 80%). The extraction was performed via the maceration method with 96% ethanol. Antibacterial activity was tested via the Kirby–Bauer disk diffusion method on Mueller–Hinton agar medium. The inhibition zone diameter data were analyzed via the Kruskal‒Wallis and Mann‒Whitney tests with a 95% confidence level. None of the concentrations of the Sembung leaf ethanol extract produced an inhibition zone against H. pylori, with a diameter of 0 ± 0 mm in all the treatment groups. The positive control exhibited an inhibition zone of 23.15 ± 0.28 mm. The Kruskal‒Wallis test revealed a significant difference (p = 0.000). However, the Mann‒Whitney U test confirmed that there was no significant difference between the negative control and all extract concentrations (p=1.000). Ethanol extracts of Blumea balsamifera leaves at concentrations ranging from 10–80% did not exhibit antibacterial activity against H. pylori in vitro, as determined via the disk diffusion method.
Prevalence, risk factors, and antimicrobial susceptibility of Pasteurella multocida and Mannheimia hemolytica: Insights from Jigjiga, Ethiopia. Ali, Mustafa Ibrahim; Fitwi, Bruk Abraha; Shimelis, Shihun; Hassan, Yahia Y.; Mohomed, Ahmed Abdi; Arog, Hassan Abdi
Svāsthya: Trends in General Medicine and Public Health Vol. 2 No. 6 (2025): November 2025
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v2i6.124

Abstract

Pasteurellosis pneumonia caused by Mannheimia hemolytica and Pasteurella multocida causes significant economic losses in sheep production and has zoonotic potential. However, epidemiological and antimicrobial resistance data from the Somali region are still limited. To estimate the prevalence of M. hemolytica and P. multocida, identify associated risk factors, and evaluate the antimicrobial resistance profile of sheep at the Jigjiga slaughterhouse in Ethiopia. A cross-sectional study was conducted from March to August 2023 in which 384 sheep lung samples at the Jigjiga slaughterhouse. Bacteriological isolation, biochemical identification, and antimicrobial susceptibility testing were performed via the disk diffusion method. Data were analyzed via STATA 16.0 with descriptive statistics, chi-square tests, and multivariate logistic regression analysis. The overall prevalence of Pasteurella spp. isolates was 26.8% (95% CI: 22.46-31.55), with M. hemolytica and P. multocida accounting for 19.79% and 7.03%, respectively. Young sheep had a 2.15-fold greater risk (OR=2.15; 95% CI: 1.33–3.48; P=0.002) than adults did. Poor body condition increased the risk by 2.44 times (OR=2.44; 95% CI: 1.18–5.04; P=0.016) compared with moderate body condition. High sensitivity to gentamicin (100% M. hemolytica, 85.71% P. multocida) and kanamycin (97.36% M. hemolytica, 92.85% P. multocida) was detected. High resistance to oxytetracycline (92.10% M. hemolytica, 100% P. multocida), tetracycline (81.52% vs. 92.85%), penicillin-G (86.84% vs. 85.71%), and ampicillin (73.52% vs. 78.57%) was detected. The prevalence of multidrug resistance reached 81.57% in M. hemolytica isolates and 92.85% in P. multocida isolates. The prevalence of Pasteurellosis in sheep in Jigjiga is quite high, with M. hemolytica being the most dominant species. Antimicrobial surveillance programs, integrated control strategies, and molecular characterization of isolates are needed.
Front and Back Matter for Volume 2 Issue 6, November 2025 Trends in General Medicine and Public Health, Svāsthya
Svāsthya: Trends in General Medicine and Public Health Vol. 2 No. 6 (2025): November 2025
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Volume 2, Issue 6, November 2025 This issue consists of 5 articles contributed by 20 authors affiliated with 9 affiliations from three countries including Indonesia (Universitas Jambi, Universitas Hindu Indonesia, Universitas Jember, Rumah Sakit Umum Pusat (RSUP) Dr. M. Djamil Padang, Politeknik Perkapalan Negeri Surabaya, Poltekkes Kemenkes Pontianak), Somalia (East Africa University), Ethiopia (Jigjiga University, Haramaya University)

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