cover
Contact Name
Reza Pratama
Contact Email
reza.pratama@bku.ac.id
Phone
+6281221673803
Journal Mail Official
jfg@bku.ac.id
Editorial Address
https://journal.bku.ac.id/jfg/index.php/jfg/about/editorialTeam
Location
Kota bandung,
Jawa barat
INDONESIA
Jurnal Farmasi Galenika
ISSN : 24069299     EISSN : 25794469     DOI : https://doi.org/10.70410/jfg
Core Subject : Health,
The aim of JFG is to become a media for the publication of articles on Pharmaceutical and related practice-oriented subjects in the pharmaceutical sciences and technology. The scope of the journal is Pharmaceutical sciences, its research and its application. The journal aims to cover the latest outstanding developments in the field of Pharmaceutical science and Technology but not limited to the following branches: Pharmaceutics Pharmaceutical technogy International Regulatory Validation Techniques Industrial Pharmacy Nanotechnology Novel Drug Delivery Systems Quality Control Quality Assurance BioTechnology Bioinformatics Proteomics Biochemistry Pharmacognosy Herbal technology Pharmacology Toxicology Pharmacy Practice Pharmacoinformatics Phytochemistry Pharmaceutical Analysis Chiral Chemistry Synthetic Chemistry Drug Development Clinical Pharmacy Pharmacogenomics Pharmacetical Engineering
Articles 5 Documents
Search results for , issue "Vol 11 No 1 (2024): Jurnal Farmasi Galenika Vol 11 No 1" : 5 Documents clear
Literature Review Analisis Utilitas Biaya Terapi Adjuvan pada Pasien Kanker Payudara HER-2 Positif Udin, Baha; Yusransyah, Yusransyah; Anita Nugraheni, Diesty
JURNAL FARMASI GALENIKA Vol 11 No 1 (2024): Jurnal Farmasi Galenika Vol 11 No 1
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v11i1.326

Abstract

Breast cancer is one of the diseases that causes death in women in the world. The high costs incurred to control cancer can affect the control of other diseases. One of the therapies given to breast cancer patients is adjuvant therapy. This review article aims to determine the cost utility of adjuvant therapy in Human Epidermal Growth Factor Receptor-2 (HER-2) Positive breast cancer patients in various countries. The article review method used is a literature review by conducting a literature study using the Pubmed and Google Scholar data bases. After conducting a literature study, 37 articles were obtained but only 4 articles met the inclusion and exclusion criteria. The articles used are articles that discuss the comparison of cost-effectiveness with quality of life as a clinical outcome of adjuvant therapy used by HER-2 Positive breast cancer patients. The articles used were conducted in 4 countries, namely the United States, Japan, the Philippines and Brazil. The results of the review of each article used show that each country has different strategies regarding costs for providing adjuvant therapy to HER-2 Positive breast cancer patients. The use of adjuvant therapy with the highest total costs, namely trastuzumab emtansine (T-DM1) in the United States (USD 218,179.98). The highest ICER value in this review article is a comparison of trastuzumab alone with the combination trastuzumab-neratinib (USD 416,106) in the United States. The therapy that produced the highest clinical outcome value of quality of life was T-DM1 (17,310) in Brazil and the United States. There is a comparison of the total cost and effectiveness of adjuvant therapy for HER-2 positive breast cancer. Differences in total costs and cost-effectiveness are influenced by research time, population, policies related to determining minimum treatment costs, currency, and research methods.
Innovation In The Development Of Black Garlic As An Ingredient In Coffee Rumaseuw, Ellen Stephanie; Ave Maria, Roma; Saptaningsih, Monica
JURNAL FARMASI GALENIKA Vol 11 No 1 (2024): Jurnal Farmasi Galenika Vol 11 No 1
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v11i1.327

Abstract

The phenomenon of coffee drinking influences thought patterns, health, and behavior in today's society. The joy of coffee comes from its taste and efficacy. Innovation the raw material for coffee in this study is black garlic with ginger powder added. Black garlic is a processed garlic product that contains an organic sulfur compound called S-allylcysteine sulfoxide, which has antioxidant properties. Another benefit of black garlic is that it can increase your body's stamina/vitality. The addition of ginger powder, which acts synergistically as an antioxidant, also contributes to the flavor of the coffee. This is expected to increase the creation of types of coffee-making ingredients that can improve taste and enhance functional benefits for human health. This study aims to determine the correct formulation of black garlic coffee with added ginger powder to have a positive impact on health. Chemical testing is performed by analyzing components such as: Antioxidants and proximate analysis, polyphenols; have potential applications in food and health products, as well as among herbal ingredients that maintain the body's stamina and vitality. The test process of sample analysis is carried out in the laboratory and the data is analyzed descriptively by presenting tables and plots of the obtained results in relation to the product potential. The technology used to develop Black Garlic Coffee is based on the processing of garlic, which is fermented for a period of time at high temperatures to produce new chemical components and recipes. This reserach have results that antioxidant content and detailed analysis of black garlic coffee could make it a globally competitive and local food that boosts stamina and vitality. This is supported by its antioxidant capacity and IC50% content of 8406.0677 ppm, low fat content of 0.20% and carbohydrate content of 37.03%. This is also supported by the moisture content of 53.02%; Ash content 1.53%; Protein 8.23%. One of the antioxidants present in black garlic coffee is total polyphenols, which have been shown containing 0.21% FeCl3 and Folin-Ciocalteu
Isolasi Dan Karakterisasi Bromelain Bonggol Nanas Dari Limbah Industri (Ananas comosus L. Merr.) Mulyani, Laida Neti; Larasti, Veny; Handayani, Dwi; Herlina, Herlina
JURNAL FARMASI GALENIKA Vol 11 No 1 (2024): Jurnal Farmasi Galenika Vol 11 No 1
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v11i1.328

Abstract

Waste of pineapple stem (Ananas comusus L. Merr.) has not been optimally utilized, although it is known that pineapple contain bromelain enzym. This research aimed to isolation and characterization bromelain from pineapple stem. Enzim was extracted from pineapple stem to produce crude enzim of bromelain. Isolation bromelain was done by amonium sulphate precepititation and continued by dialysis. Characterization to determined molecular weight, protein content and protease activity. The result of fractionation by amonium precipitation showed the highest specific activity on amonium sulphate 40-60% fraction 1011,98 U/mg. Caharacterization of purified bromelain showed that molecular weight of bromelain is 23,69 dan 24,72 kD with proteint content 2,78 mg/mL and protease activity is 2833,33 U/mL. This study concluded that the pineapple stem has bromelain enzym with the protease activity.
Hubungan Tingkat Pengetahuan Dan Sikap Masyarakat Tentang Dagusibu Obat Di Desa Lebakwangi Kecamatan Arjasari Kabupaten Bandung Roni, Asep; Sri Mas Hartini, Ni Nyoman; Dista Asmarani, R. Mayang
JURNAL FARMASI GALENIKA Vol 11 No 1 (2024): Jurnal Farmasi Galenika Vol 11 No 1
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v11i1.329

Abstract

DAGUSIBU is an effort to improve health for the community which is carried out through health service activities by pharmaceutical staff. DAGUSIBU (Get, Use, Save, Throw Away) is a Drug Awareness Family Movement Program initiated by the Indonesian Pharmacists Association to achieve public understanding and awareness of the correct use of drugs. Based on the results of Riskesdas Basic Health research in 2013, it shows that 35.2% of households store medicines for self-medication. Referring to the 35.2% of households that store medicines, 35.7% of them store hard medicines, and 27.8% of them store antibiotics and 86.1% of these antibiotics were obtained without a prescription. The aim of this research is to find out to what extent the general public in Lebakwangi Village, located in Arjasari District, Bandung Regency, knows about Dagusibu medicine. The method used in this research is descriptive quantitative using a One Group Pretest and Posttest design with an accidental sampling approach. The results of the research showed that having a level of knowledge in the good category regarding DAGUSIBU Medicine had increased by 27%, and having a level of attitude towards DAGUSIBU Medicine in the good category had increased by 16%. The level of public knowledge is related to attitudes. Based on the results of the Spearman correlation test, it shows a p value of 0.048.
Uji Aktivitas Antioksidan Ekstrak Buah Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl.) Yang Diformulasikan Kedalam Sediaan Masker Gel Zaelani, Diki; Pratama, Reza; Japar Sodik, Jajang; Hilda Restu, Afria
JURNAL FARMASI GALENIKA Vol 11 No 1 (2024): Jurnal Farmasi Galenika Vol 11 No 1
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v11i1.330

Abstract

This study utilizes the Phaleria macrocarpa fruit (Phaleria macrocarpa (Scheff.) as an active ingredient in gel mask formulation due to its widespread use as a medicinal plant and its antioxidant properties that can inhibit free radicals. The research began with the collection of the fruit from the experimental garden in Lembang-Bandung, identified as Phaleria macrocarpa (Scheff.) Boerl. Extraction was conducted using the maceration method with 96% ethanol for 3x24 hours. Phytochemical screening results indicated the presence of alkaloids, flavonoids, tannins, triterpenoids, and steroids. Antioxidant activity of the gel masks was tested using the DPPH immersion method, resulting in IC50 values of 60.18 ppm, 57.18 ppm, and 54.82 ppm for three different formulations. The pure extract had an IC50 of 45.11 ppm. The gel masks remained stable despite changes in pH and viscosity, with formulation 2 being the most preferred according to the hedonic test. In conclusion, the Phaleria macrocarpa gel mask exhibits effective antioxidant activity and good stability.

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