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Contact Name
Waras Nurcholis
Contact Email
wnurcholis@apps.ipb.ac.id
Phone
+628179825145
Journal Mail Official
jurnaljamuindonesia@apps.ipb.ac.id
Editorial Address
Tropical Biopharmaca Research Center (TropBRC) IPB University CRC Building, 2nd Floor, STP Area IPB Taman Kencana Campus Taman Kencana St. No. 3, Bogor West Java, Indonesia 16128
Location
Kota bogor,
Jawa barat
INDONESIA
Indonesian Journal of Jamu
ISSN : 24077178     EISSN : 24077763     DOI : https://www.doi.org/10.29244/jji
Jurnal Jamu Indonesia (JJI) is dedicated to the exchange of information and widespread scientific understanding regarding the development of the world of herbal medicine through the publication of scientific papers. The themes of scientific papers within the scope of JJI include the theme of herbal medicine research from upstream to downstream which is not limited to ethnobotanical research and local knowledge, exploration, conservation, domestication of biological resources related to herbal medicine, variety breeding, development of Good Agricultural and Collection Practices (GACP) for herbal medicine raw materials, development of standards for raw materials and herbal medicine products, development of herbal medicine products, identification of active compounds and their synthesis, working mechanisms for the bioactivity of herbal medicine formulas, social and economic aspects related to the development of herbal medicine.
Articles 212 Documents
Antihypertensive Jamu Supplementation Improves Blood Pressure and Renal Oxidative Stress Markers in Fructose-Fed Rats Sri Teguh Rahayu; Aprilita Rina Yanti Eff; Yonatan Eden; Anna Yuliana
Jurnal Jamu Indonesia Vol. 11 No. 5 (2026): Jurnal Jamu Indonesia (In Progress)
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v11i5.510

Abstract

High fructose consumption induces hypertension and renal oxidative stress, and herbal supplements (jamu) are potential agents for reversing this damage. This study examined the antihypertensive and antioxidant activity of a jamu formulation by measuring blood pressure and renal superoxide dismutase (SOD), glutathione (GSH), and malondialdehyde (MDA) levels in fructose-induced rats. Thirty Sprague-Dawley rats were divided into six groups: jamu at 0.01 (A1), 0.02 (A2), and 0.03 g/kg body weight (BW) (A3); captopril as the positive control (PC); negative control (NC); and normal control (SC). Rats received 10% fructose for 8 weeks to induce hypertension, continuing concurrently during the 2-week treatment period (weeks 9–10). Jamu supplementation significantly reduced blood pressure and MDA levels and increased SOD activity and GSH levels compared with the NC group (p < 0.05). Two weeks of jamu administration exerted antihypertensive and antioxidant effects, improving blood pressure control and renal oxidative stress markers in fructose-fed rats.
Analysis of Antioxidant Activity, Total Phenolic and Flavonoid Contents of Ethyl Acetate Extracts from Carica papaya L. Seeds and Peels Gemmy Sarina; Mellova Amir; Atalia Defira Wardhani; Nurjannah Bachri
Jurnal Jamu Indonesia Vol. 11 No. 5 (2026): Jurnal Jamu Indonesia (In Progress)
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v11i5.578

Abstract

Papaya seeds and peels are underutilized by-products containing antioxidant-associated phytochemicals. This study compared ethyl acetate extracts of Carica papaya L. seeds and peels prepared using matrix-specific ultrasound-assisted extraction conditions. Total phenolic content was determined by the Folin–Ciocalteu method, total flavonoid content by the aluminum chloride colorimetric method, and antioxidant activity by the DPPH assay. Peel extract contained higher total phenolic and flavonoid contents than seed extract, at 12.076 ± 0.091 versus 6.699 ± 0.087 mg GAE/g and 75.983 ± 1.089 versus 39.604 ± 1.169 mg QE/g, respectively. DPPH IC₅₀ values were 91.78 ± 0.99 ppm for peel, 815.79 ± 3.77 ppm for seed, and 6.62 ± 0.01 ppm for ascorbic acid. Under the extraction conditions applied, peel showed greater antioxidant-associated responses than seed, although the comparison should not be interpreted as intrinsic tissue superiority.

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