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Waras Nurcholis
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Tropical Biopharmaca Research Center (TropBRC) IPB University CRC Building, 2nd Floor, STP Area IPB Taman Kencana Campus Taman Kencana St. No. 3, Bogor West Java, Indonesia 16128
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INDONESIA
Indonesian Journal of Jamu
Published by Institut Pertanian Bogor
ISSN : 24077178     EISSN : 24077763     DOI : https://www.doi.org/10.29244/jji
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Medicine & Pharmacology
Jurnal Jamu Indonesia (JJI) is dedicated to the exchange of information and widespread scientific understanding regarding the development of the world of herbal medicine through the publication of scientific papers. The themes of scientific papers within the scope of JJI include the theme of herbal medicine research from upstream to downstream which is not limited to ethnobotanical research and local knowledge, exploration, conservation, domestication of biological resources related to herbal medicine, variety breeding, development of Good Agricultural and Collection Practices (GACP) for herbal medicine raw materials, development of standards for raw materials and herbal medicine products, development of herbal medicine products, identification of active compounds and their synthesis, working mechanisms for the bioactivity of herbal medicine formulas, social and economic aspects related to the development of herbal medicine.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 193 Documents
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Formulation and Physicochemical Characterization of Herbal Facial Wash Containing Moringa oleifera and Solanum lycopersicum Extracts Novaliana Devianti Sagita; Meylani Sutoro; Syifa Salsabilla; Reza Pratama
Jurnal Jamu Indonesia Vol. 11 No. 3 (2026): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v11i3.471

Abstract

Cleansing products based on plant extracts require acceptable physicochemical properties and retained antioxidant activity. This study formulated a herbal facial wash containing Moringa oleifera leaf extract and Solanum lycopersicum fruit extract and evaluated its physicochemical characteristics and antioxidant activity. Three formulas were prepared with different excipient compositions and assessed for organoleptic properties, pH, viscosity, foaming ability, free alkali content, phytochemical profile, TLC pattern, and DPPH radical-scavenging activity. Phytochemical screening detected flavonoids, tannins, saponins, alkaloids, quinones, and triterpenoids. The selected formulation showed chromatographic bands comparable to the extracts, indicating retention of major constituents after formulation. The IC₅₀ values were 30.891 ± 0.40 µg/mL for M. oleifera extract, 50.532 ± 0.92 µg/mL for S. lycopersicum extract, and 46.350 ± 0.08 µg/mL for the selected facial wash. These results indicate that the extracts can be incorporated into a facial wash with measurable antioxidant activity.
Metabolite Profiling and Cytotoxicity of Bajakah Tampala (Uncaria lanosa var. ferrea) Stem Fractions Against Breast Cancer Cells Mashuri Yusuf; Muhaimin Muhaimin; Riezki Amalia; Iskandar Yoppi
Jurnal Jamu Indonesia Vol. 11 No. 3 (2026): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v11i3.498

Abstract

Bajakah Tampala (Uncaria lanosa var. ferrea (Blume) Ridsdale) has been used in traditional medicine, but its cytotoxic activity against breast cancer cells remains insufficiently characterized. This study evaluated the cytotoxicity of U. lanosa stem fractions against MCF-7 breast cancer cells and profiled metabolites in the most active fraction. The stem extract was fractionated using hexane, ethyl acetate, and water, and cytotoxicity was assessed using the WST-8 assay. Metabolite profiling was performed using UHPLC-HRMS. Among the plant fractions, the hexane fraction showed the lowest IC₅₀ value, 105.37 ± 2.51 µg/mL, followed by the ethyl acetate fraction, 130.58 ± 13.41 µg/mL, and the water fraction, 209.91 ± 16.48 µg/mL. Cisplatin showed a markedly lower IC₅₀ value of 4.50 ± 1.92 µg/mL. UHPLC-HRMS tentatively identified ten metabolites in the hexane fraction. These findings indicate that U. lanosa var. ferrea stem fractions exhibit measurable cytotoxic activity against MCF-7 cells.
Ultrasound-Assisted Extraction Enhances Phenolic, Flavonoid, and Antioxidant Profiles of Spatholobus littoralis Roots Muchammad Reza Ghozaly; Berna Elya; Muhammad Hanafi; Heri Setiawan
Jurnal Jamu Indonesia Vol. 11 No. 3 (2026): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v11i3.501

Abstract

Spatholobus littoralis Hassk. roots contain antioxidant-related compounds whose recovery may be influenced by extraction method and solvent polarity. This study compared ultrasound-assisted extraction and microwave-assisted extraction using n-hexane, ethyl acetate, and 96% ethanol to evaluate their effects on total phenolic content, total flavonoid content, and DPPH radical-scavenging activity. Among the tested conditions, 96% ethanol combined with ultrasound-assisted extraction produced the highest phenolic content, flavonoid content, and antioxidant activity, with values of 89.33 mg GAE/g, 40.10 mg QE/g, and IC₅₀ 72.27 µg/mL, respectively. Strong negative correlations were observed between DPPH IC₅₀ and both total phenolic content (r = −0.961) and total flavonoid content (r = −0.941). These findings indicate that ultrasound-assisted extraction with 96% ethanol was the most effective condition for obtaining antioxidant-rich S. littoralis root extract in this study.

Page 20 of 20 | Total Record : 193

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