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Lombok Medical Journal
Published by Universitas Mataram
ISSN : -     EISSN : 28277686     DOI : -
Core Subject : Health, Science, Engineering,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Mechanical Engineering Public Health
Lombok Medical Journal (LMJ) is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, community or public health research, and medical education to integrate researches in all aspects of human health. This journal publishes original articles, reviews, and case reports. Brief communications containing short features of medicine, latest developments in diagnostic procedures, treatment, or other health issues that is important for the development of health care system are also acceptable. Focus and Scope of Lombok Medical Journal (LMJ): Basic Science, Clinical Research, Community or public health research, Medical Education
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 156 Documents
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A Gambaran Kadar Asam Urat pada Pasien Hemodialisis rutin di RSUD Provinsi NTB: Gambaran Kadar Asam Urat pada Pasien Hemodialisis rutin di RSUD Provinsi NTB Ni Komang Miraditi Miraditi; I Gede Yasa Asmara; Raehanul Bahraen
Lombok Medical Journal Vol. 3 No. 3 (2024): Lombok Medical Journal Volume 3 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i3.3716

Abstract

According to the United States Renal Data System, there were 124,411 patients with end-stage renal disease (ESRD) in 2015, and the number is estimated to increase by 20,000 cases per year. The decline in kidney function in ESRD patients leads to various clinical conditions, one of which is an increase in blood uric acid levels. Studies on patients who have not undergone hemodialysis (HD) found that 86.7% of patients experienced hyperuricemia, compared to 73.3% of patients who had already undergone HD. This study aims to describe the uric acid levels in ESRD patients undergoing HD at the NTB Provincial Hospital. This research used an analytical observational method with a cross-sectional study design based on secondary data (medical records) of ESRD patients undergoing HD at the NTB Provincial Hospital from January to August 2021. The sampling technique used was consecutive sampling. The data obtained were then analyzed using the Statistical Package for Social Sciences (SPSS). Among the 127 samples, the average uric acid level in HD patients was found to be 8.0 mg/dl, with 83 patients (65.4%) having hyperuricemia. More male patients (43 or 51.8%) had hyperuricemia compared to female patients (40 or 48.2%), and the highest incidence of hyperuricemia was found in patients aged 40-59 years, accounting for 67.5%. Bivariate chi-square analysis showed no significant association between uric acid levels and gender (p=0,590), age (p=0,152), duration of HD (p=0,730), or history of anti hyperuricemic treatment (p=0,613). This study concludes that the incidence of hyperuricemia in HD patients is high. Uric acid levels are not associated with age, gender, duration of hemodialysis, or history of anti-hyperuricemic treatment.
Peran Neurorestorasi pada Pasien Post Stroke Ni Nyoman Ayu Susilawati; Rizqi Al Kasiron; Hidzul Mahidza Falah; Rizkia Wiyani Putri; Siska Julia Cindy W; Herpan Syafii H; Catur Ari Setianto
Lombok Medical Journal Vol. 3 No. 3 (2024): Lombok Medical Journal Volume 3 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i3.3960

Abstract

Stroke penyebab utama kecacatan dan kematian ketiga setelah penyakit jantung dan keganasan (Feigin dkk, 2022). Prevalensi stroke di Indonesia (Riskesdas 2018) meningkat 56% dalam 5 tahun (7 kasus/1000 penduduk tahun 2013 menjadi 10,9 kasus/1000 penduduk tahun 2018). Dengan meningkatnya harapan hidup dan faktor risiko stroke, perkiraan jumlah penderita stroke mencapai lebih dari 1 juta orang pada tahun 2050 (Dirjen Yankes, 2024). Neurorestorasi merupakan proses untuk memulihkan, meningkatkan, atau mempertahankan integritas fungsi neurologis dengan strategi neurorestoratif, termasuk fisik (elektronik atau magnetik), kimiawi (obat atau agen kimia), biologis (terapi sel, molekul, bioteknologi, dan rekayasa jaringan), bedah, atau jenis intervensi lainnya, yang dapat memulihkan struktur dan/atau fungsi saraf secara bersamaan. Mekanisme neurorestoratif dalam sistem saraf pusat (SSP) meliputi neuroprotektif, neuromodulasi, neuroplastisitas (neurosinapsis, sirkuit saraf, atau rekonstruksi jaringan), imunomodulasi, regenerasi aksonal, remielinasi, neuroregenerasi (neurogenesis) dan angiogenesis (Huang dan Chen, 2015; Gunduz dkk, 2023).Berbagai metode terapi neurorestorasi dan neurorehabilitasi pasca stroke dapat digunakan meningkatan neuroplastisitas seperti non invasive brain stimulation repetitive transcranial magnetic stimulation (rTMS), transcranial direct current stimulation (tDCS), terapi Stem cell, deep brain stimulation, virtual reality (VR), terapi musik, terapi kovensional seperti terapi fisik, terapi wicara. Terapi kombinasi berbagai modalitas terapi ini terbukti lebih signifikan memberikan hasil yang lebih baik dibandingkan terapi tunggal atau terapi konvensional
Faktor Predisposisi Stigma dan Diskriminasi serta Upaya Peningkatan Kualitas Hidup Pasien terdiagnosis HIV/AIDS Ni Wayan Puspa Wijaya Suryantarini
Lombok Medical Journal Vol. 3 No. 2 (2024): Lombok Medical Journal Volume 3 Nomor 2
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i2.3990

Abstract

HIV/AIDS menjadi salah satu kondisi yang menemui hambatan dalam upaya peningkatan kualitas hidup pasien yakni dengan masih berkembangnya stigma dan diskriminasi HIV/AIDS di kalangan masyarakat. Di samping progresi penyakit yang berdampak terhadap kesehatan fisik dan kehidupan sosial pasien, tekanan akibat stigma dan diskriminasi mengisolasi pasien dengan perasaan takut dan stres yang berlebihan. Masyarakat memiliki sejumlah karakteristik yang menjadi faktor predisposisi munculnya stigma dan diskriminasi tersebut. Peran menyeluruh sektor kehidupan dalam memerangi gejolak stigma dan diskriminasi akan sangat membantu mempercepat penyembuan pasien termasuk memberikan kehidupan yang lebih baik bagi pasien terdiagnosis HIV/AIDS. Dukungan masyarakat dapat berupa peningkatan kesadaran dan pengetahuan melalui sosialisasi, komunitas, dan kampanye terkait HIV/AIDS. Tinjauan pustaka ini merangkum sejumlah bentuk stigma dan diskriminasi yang kerap dihadapi pasien terdiagnosis HIV/AIDS, faktor-faktor di masyarakat yang berhubungan dengan hal tersebut, serta faktor dan upaya peningkatan kualitas hidup pasien melalui penghapusan stigma dan diskriminasi dengan dukungan dari pemerintah, pelayanan kesehatan, dan masyarakat umum.
Visual Impairment in High Flow Carotid-Cavernous Fistula: Case Report Setyawati Asih Putri; I Gusti Lanang Krisna Wiracakra
Lombok Medical Journal Vol. 3 No. 2 (2024): Lombok Medical Journal Volume 3 Nomor 2
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i2.4499

Abstract

Carotid-cavernous fistula (CCF) is the most common abnormal connection between the carotid artery and the cavernous sinus. There are 2 types of CCF: direct and indirect. Direct CCF is a high-flow fistula that occurs due to a tear in the carotid artery, most often caused by penetrating or nonpenetrating head trauma. Visual disturbances can be one of the symptoms of CCF in post-traumatic patients. With proper diagnosis and management, the patient's condition can significantly improve. A 22-year-old man came with symptoms of bilateral chemosis and bilateral proptosis, which had developed progressively for 1 month. The patient had a history of a traffic accident 2 months before with mandibular trauma. The patient had undergone mandibular surgery, but at that time, no neurological symptoms had appeared. Physical examination revealed bilateral chemosis, bilateral proptosis, blurred vision and oftalmoplegi with diplopia. Magnetic Resonance Angiography (MRA) of the head showed features that led to a diagnosis of carotid-cavernous fistula. Cerebral angiography was performed and confirmed there was a high-flow carotid-cavernous fistula. Endovascular intervention was performed, and a decision was made to perform balloon embolization. Four months after the procedure, the patient's complaints improved, blurred vision decreased, and proptosis disappeared. Based on this case report, carotid-cavernous fistula can be used as a differential diagnosis for the cause of visual impairment in post-head trauma patients. Appropriate management can treat the patient's clinical symptoms
Patofisiologi Ensefalitis pada Rabies Safat Wahyudi; Raditya Rachman Landapa
Lombok Medical Journal Vol. 3 No. 2 (2024): Lombok Medical Journal Volume 3 Nomor 2
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i2.4527

Abstract

Rabies, disebabkan oleh Rabies Lyssavirus, virus neurotropik yang menargetkan neuron dan menyebar sepanjang sel saraf, menghasilkan disfungsi neuronal. Virus ini menunjukkan neurotropisme dan neuro-invasivitas yang kuat, menyebabkan manifestasi neurologis yang parah. Penularan penyakit ini biasanya melalui gigitan hewan yang terinfeksi, memungkinkan virus masuk ke dalam tubuh dan bereplikasi sebelum mencapai otak atau medula spinalis. Rabies muncul dalam dua bentuk yang berbeda, yaitu ensefalitik dan paralitik, dengan rabies ensefalitik lebih umum dan ditandai dengan gejala klasik seperti hidrofobia dan aerofobia. Tanda-tanda awal dapat mencakup kesemutan pada anggota tubuh tanpa gangguan kognitif. Pemahaman terhadap patofisiologi serta interaksi antara virus Rabies dan host, antara lain mekanisme masuknya virus, replikasi, dan penyebaran dalam sistem saraf sangat penting untuk menjelaskan tentang proses perjalanan penyakit, termasuk perubahan perilaku yang terjadi. Pencegahan rabies melibatkan vaksinasi yang tepat waktu setelah paparan, sementara pengobatan pasca-infeksi yang adekuat hingga saat ini masih menjadi tantangan.
Perjalanan Udara pada Pasien Penyakit Paru ObstruktifF Kronik widiasari Komang Sri Rahayu Widiasari; Muhammad Mirsa Nidzarsyah; Mc. Syaiful Ghazi Yamani
Lombok Medical Journal Vol. 3 No. 3 (2024): Lombok Medical Journal Volume 3 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i3.4624

Abstract

ABSTRAK Melalui perkembangan tatalaksana yang memadai bagi pasien PPOK seperti rehabilitasi, terapi oksigen jangka panjang, dukungan oksigen rawat jalan, dan ventilasi non-invasif membantu pasien menjadi lebih aktif secara fisik dan bergerak. Alih-alih hanya berdiam diri di rumah, sebagian besar pasien PPOK biasanya tetap melanjutkan kehidupan sehari-hari, seperti pergi keluar, berolahraga, dan tentu saja bepergian. Dalam beberapa tahun terakhir, perjalanan udara menjadi moda transportasi pilihan pertama karena cepat, praktis, dan semakin murah. Menurut data Bank Dunia, 3,696 miliar orang menggunakan perjalanan udara komersial di seluruh dunia pada tahun 2016. Sekitar 2 miliar penumpang pesawat udara melakukan perjalanan udara setiap tahunnya dan 18-44% nya merupakan pasien PPOK. Sementara itu, efek dari peningkatan ketinggian dapat mengakibatkan hipoksia. Individu yang sehat merespons hipoksia dengan meningkatkan ventilasi, menyeimbangkan perubahan hipobarik tanpa gejala apa pun. Ventilasi dapat ditingkatkan dengan meningkatkan volume tidal dan/atau meningkatkan laju pernapasan. Namun, meningkatkan volume tidal untuk mereka yang menderita PPOK, merupakan tugas yang sulit karena mereka sering mengalami hiperinflasi. Ketinggian dan perjalanan udara bagi pasien PPOK dapat memicu munculnya gejala klinis yang mengganggu selama perjalanan terutama bagi penderita PPOK sedang hingga berat. Metode/tes yang paling umum digunakan untuk evaluasi sebelum penerbangan yaitu saturasi oksigen dengan pulse oximetry, analisis gas darah arteri (AGD), tes fungsi paru (spirometri), tes jalan 6 menit (6 minutes walking test) dan Hypoxic Challenge Testing (HCT). Pengukuran saturasi oksigen merupakan test yang paling mudah dilakukan dan dapat menjadi acuan awal. Menurut literatur jika saturasi oksigen pada penderita PPOK berada di bawah 92% maka harus diresepkan terapi oksigen tambahan. Selain menggunakan pulse oximetry, tes lanjutan yang dapat digunakan untuk menilai kelaikan terbang pada pasien PPOK adalah Hypoxic Challenge Testing. HCT adalah tes yang menjadi tolak ukur dan direkomendasikan oleh British Thoracic Society (dengan hasil HCT PaO2 ≥ 50mmHg atau SpO2 ≥ 85%, oksigen dalam penerbangan tidak diperlukan; PaO2 < 50mmHg atau SpO2 < 85%, oksigen direkomendasikan; dan jika diperlukan titrasi oksigen untuk mempertahankan PaO2 ≥ 50mmHg atau SpO2 ≥85% pada dewasa dan SpO2 90% untuk anak usia 1 tahun keatas) Kata Kunci : Perjalanan Udara, Penerbangan, PPOK, Hypoxic Challenge Testing
Identifikasi Faktor Risiko Perforasi Gaster Pada Pasien Usia 18-33 Tahun di Rumah Sakit Umum Daerah Kabupaten Sumbawa Periode Tahun 2020 Lalu Fahril Ilham; Lalu Fauzan Adi Yuliansyah
Lombok Medical Journal Vol. 4 No. 1 (2025): Lombok Medical Journal Volume 4 Nomor 1
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v4i1.4899

Abstract

Gastric perforation is the leakage of stomach acid into the abdominal cavity which will cause peritonitis and is an emergency. The risk of mortality due to the disease is 10 times greater than other acute abdominal diseases. One of the efforts to prevent gastric perforation is to know the risk factors that can increase the possibility of this disease. This study uses a retrospective descriptive method. Samples were taken using the total sampling technique. The data used are secondary data using medical record data from patients diagnosed with gastric perforation with an age range of 18-33 years in the 2020 period at the Sumbawa Regency Regional General Hospital. A total of 13 people suffered from gastric perforation at the age of 18-33 years with an average age of respondents of 23 years. All respondents were of different genders (100%). A total of 12 people (92.3%) had a smoking habit and 8 people (61.5%) consumed alcohol. There was 1 person (7.6%) with a history of Gastroesophageal Reflux Disease (GERD) and 5 people (38.4%) suffered from peptic ulcers disease. 15.4% of respondents had a history of consuming Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and 92.3% with a history of consuming traditional herbal medicine containing Curcumae rhizoma, Zingiberis rhizoma, Zingeberis aromaticae, and caffeine. In this study, all respondents were male and the average age was 23 years in the age range of 18-33 years. Risk factors found in respondents were smoking habits, alcohol consumption, history of Gastroesophageal Reflux Disease (GERD) and peptic ulcers disease, consumption of NSAIDs and traditional herbal medicine containing Curcumae rhizoma, Zingiberis rhizoma, Zingeberis aromaticae, and caffeine which have relaxing side effects and become addictive after consuming them.
Kedaruratan Kesehatan Masyarakat akibat Cacar Monyet (Mpox) Hamsu Kadriyan
Lombok Medical Journal Vol. 3 No. 3 (2024): Lombok Medical Journal Volume 3 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i3.5315

Abstract

With the declaration of a public health emergency concerning Mpox (monkeypox), vigilance and mitigation measures are necessary to prevent the adverse effects of this condition. In Indonesia, 88 new cases have been reported, primarily of the Clade II variant. However, new Mpox variants, such as Clade Ia and Ib, have also been identified. This situation requires careful attention and multidisciplinary management to achieve optimal outcomes.
Peran Insulin-like Growth Factor-1 (IGF-1) terhadap Penyakit Kardiovaskular Fitrianisa Faradina Zubadi; Herpan Harahap; Legis Saputri; Arina Windri Rivarti
Lombok Medical Journal Vol. 3 No. 3 (2024): Lombok Medical Journal Volume 3 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i3.5379

Abstract

Insulin-like growth factor 1 (IGF-1) is a major regulator of somatic growth that mediates the effects of growth hormone (GH). IGF-1 receptors are expressed by three major cells involved in the pathogenesis of atherosclerosis, namely endothelial cells, macrophages, and smooth muscle cells. Recent in vivo studies have discussed the effects of IGF-1 on the pathogenesis of atherosclerosis. This paper will discuss the relationship and role of IGF-1 in heart and blood vessel disease.
Hyperthyroid Status with Glycemic Control in Patients with type 2 Diabetes Mellitus at Peripheral Hospital Jolanda Nahak; Julency
Lombok Medical Journal Vol. 4 No. 1 (2025): Lombok Medical Journal Volume 4 Nomor 1
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v4i1.5413

Abstract

By 2030, it is estimated that the number of patients with type 2 diabetes mellitus (T2DM) in Indonesia will increase from 8.4 million to 21.3 million. Thyroid dysfunction (TD) has an impact on the glycemic control of patients with T2DM. This case report explores a case of a T2DM patient, with hyperthyroidism and glycemic control in a peripheral hospital, including Pre Hospital, Intra Hospital, and Post Hospital status. In this case, a 25-year-old woman presented with typical thyroid symptoms accompanied by a significant increase in blood glucose, the patient was carried out strict glycemic control in the ward, although no treatment was carried out in the intensive care unit (ICU) due to limited facilities, but on the fourth day of treatment the patient's clinical condition improved and blood glucose level was controlled. In our report, in pre-, intra, and post-hospital, type 2 DM patients with hyperthyroid status, following glycemic control before, during, and after hospitalization, we found that routine blood glucose levels monitoring had a positive impact on the patient's clinical condition in these 3 time periods. Therefore, it is essential to screen for TD in T2DM patients as each of the high cardiovascular risks in patients with diabetes mellitus and thyroid.

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