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INDONESIA
Indonesian Journal Health Science and Medicine
Published by Universitas Muhammadiyah Sidoarjo
ISSN : -     EISSN : 30638186     DOI : https://doi.org/10.21070/ijhsm
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health Veterinary
Focus: The Indonesian Journal on Health Science and Medicine (IJHSM) focus to advance the field of health science and medicine by publishing high-quality, peer-reviewed research articles, reviews, and case studies. Our journal serves as a platform for researchers, clinicians, and healthcare professionals to share innovative findings, critical insights, and emerging trends in the broad domain of health science and medicine. Scope: Clinical Research and Practice Studies on the diagnosis, treatment, and prevention of diseases. Clinical trials and evidence-based practices. Advances in medical technology and therapeutics. Public Health Epidemiology and health statistics. Health policy and management. Community health initiatives and health education. Biomedical Science Research on cellular and molecular biology. Genetics and genomics. Pharmacology and toxicology. Health Care Systems and Services Health care delivery and management. Quality improvement in health care services. Health economics and health informatics. Global Health Health issues affecting populations worldwide. International health regulations and practices. Global health governance and diplomacy. Health Promotion and Disease Prevention Lifestyle and behavioral interventions. Preventive medicine and early detection. Nutritional science and physical activity. Mental Health Research on mental health disorders and treatments. Psychological well-being and mental health promotion. Integration of mental health services in primary care. Innovations in Health Education and Training Medical and health science education methodologies. Training programs for health professionals. Continuing education and professional development.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 268 Documents
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Molecular Detection of OXA-143 beta-lactamase gene in P. aeruginosa: Deteksi molekuler gen beta-laktamase OXA-143 pada P. aeruginosa Abed, Jasim Mohammed; Al-Khamis, Ahmed Ramadan Hadabi; Sameer, Hamid Kadhim; Hassun, Ahmed Faleh
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i2.125

Abstract

Pseudomonas aeruginosa, an opportunistic-bacteria that causes many clinical and hospital infections, struggles to be treated due to its drug resistance. This bacterium resists beta-lactams by producing broad-spectrum beta-lactamases. This study will determine antibiotic resistance and identify the blaOXA-143 gene in clinical P. aeruginosa isolates. This study isolated P. aeruginosa from patients using McConkey agar. Gram staining, oxidase, catalase, MRVP, motility in SIM medium, and fluorescent pigment synthesis on cetrimide agar identified and validated P. aeruginosa isolates. DNA was extracted from isolates using the kit. Primers were created and confirmed using NCBI. PCR was used to detect blaOXA-143. The 16S rRNA gene was PCR-analyzed to confirm the isolates and test the PCR test. P. aeruginosa was isolated from 100 samples: blood (36%), urine (30%), wound (20%), and trachea (14%). Penicillin had 100% resistance in a study of 100 P. aeruginosa isolates, followed by cefixime at 86%. Ipenem, meropenem, calcitin, and cefotaxime had resistance rates of 42%, 40%, 68%, and 50%, respectively. The lowest Cefepim resistance was 34%. In this investigation, 47% of isolates were multidrug-resistant. All isolates were verified by 16SrRNA detection. None of the isolates had the blaOXA-143 gene. Highlights: aeruginosa shows high resistance to multiple antibiotics. 47% isolates were multidrug-resistant, confirmed via 16S rRNA. blaOXA-143 gene was not detected in any isolates. Keywords: P. aeruginosa, beta lactamase, Oxacillinase, blaOXA143
Ovarian Histopathological Lesions by Superovulation Induction Drugs Intake in Female Rats: Lesi Histopatologi Ovarium oleh Asupan Obat Induksi Superovulasi pada Tikus Betina Mazyed, Ibtihal K.; Al-badry, Fatima A.
Indonesian Journal on Health Science and Medicine Vol. 2 No. 3 (2025): Desember
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i3.126

Abstract

This study was conducted to determination the effects of fertility drugs on some sex hormones and the histological changes of the ovary. Forty-two of female rats were used, it divided into sevsn groups, each group containing 6 rats. The first group was fed with distilled water and feed as control group. The second and third groups were received Clomid (50 mg) for one month and two months respectively. The fourth and fifth groups were given Duphaston (10 mg) for one month and two months respectively. The sixth and seventh groups were treated with the Procreation V for one and two months. The results showed a singnificant increasing in levels of sex hormones (estrogen, progesterone and prolactin) in addition to histological damage such as the decline of ovarian follicles with congestion, edema, fibrosis, bleeding, increasing thickness of germinal layers and inflammation, as it was found that exposure to them for a period of two months is the most harmful. Highlights: Drugs increased estrogen, progesterone, and prolactin levels significantly. Histological damage: follicle loss, inflammation, fibrosis, bleeding. Two-month exposure caused the most severe ovarian harm. Keywords: Fertility drugs, ovary, progesterone, histological lesions
A Study Regarding the Basic Anatomy and Physiology of the Eye among Nursing Students: A Cross-Sectional Study: Studi Mengenai Anatomi dan Fisiologi Dasar Mata di Kalangan Mahasiswa Keperawatan: Sebuah Studi Cross-Sectional Hamid, Samahir Sabri; Kareem, Afkar Fadhil; Tiryag, Ali Malik; Abdul-Ra’aoof, Husham Hussain
Indonesian Journal on Health Science and Medicine Vol. 2 No. 2 (2025): Oktober
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i2.127

Abstract

Objective: to determine the correlation between students' demographic information (age, sex, and stage) and their knowledge of the anatomy and physiology of the eye. Methods: A cross-sectional study was conducted at the College of Nursing at the Bab Al-Zubair Campus in Al-Basrah City. Nursing students are a sample of the study (100), and purposive (non-probability) sampling. The period of the study extended from the 12th of May 2024 to the 10th of February 2025. The questionnaire was constructed by the researchers on reliability (Cronbach’s alpha) for 32 items (0.81) and validity of the questionnaire by 13 experts in the field. Results: The findings of these results indicate that most students (60%) have moderate knowledge about the anatomy and physiology of the eye, and (40%) have good knowledge. Conclusion: The results of the study show that most students only have a moderate knowledge of the anatomy and physiology of the eye Highlights: Assess link between demographics and eye anatomy knowledge. Cross-sectional study using questionnaire with 100 nursing students. Most students had moderate understanding of eye anatomy.. Keywords: Nursing, Students, Anatomy, Physiology, Eye
Study and Microbiologic Analysis of Klebsiella spp. Isolated from Urinary Tract Infections Clinical Samples in Kirkuk City: Studi dan Analisis Mikrobiologi Klebsiella spp. yang Diisolasi dari Sampel Klinis Infeksi Saluran Kemih di Kota Kirkuk Hussein, Rakan A.; Aziz, Fatema W. Abdul
Indonesian Journal on Health Science and Medicine Vol. 2 No. 3 (2025): Desember
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i3.128

Abstract

Background: Klebsiella pneumoniae is a prevalent cause of urinary tract infections (UTIs), which are a serious issue of public health. Since K. pneumoniae strains are developing increasing resistance to antibiotics, prompt and precise diagnosis is necessary for successful treatment. Aim: The purpose of this study was to separate and recognize K. pneumoniae from UTI patients' samples of urine. Additionally, it aimed to assess the efficacy of several diagnostic techniques, such as Vitek 2, biochemical, and phenotypic. Method: The study, which included both governmental and commercial healthcare facilities, was carried out in Kirkuk province, Iraq, between January and October of 2024. Urine samples were taken from 90 UTI patients, representing both sexes and an extensive range of age groups. The study used various diagnostic techniques. For initial identification, phenotypic and biochemical testing were conducted. The automated Vitek 2 system provides quick and precise identification. Results: 33.4% of the urine samples had K. pneumoniae. The age range of 5 to 25 years old had the highest prevalence, and girls were more likely than males to have it. All of the diagnostic methods used in the investigation were successful in confirming every isolate. Conclusion: The study concluded that K. pneumoniae had a major role in the investigated group's UTIs. The results stress the importance of utilizing a variety of techniques for diagnosis in order to accurately and promptly identify this disease, This is necessary for both infection prevention and successful treatment. Highlights: pneumoniae increasingly causes UTIs and resists antibiotic treatment. Urine samples tested using phenotypic, biochemical, and Vitek 2 methods. 4% positive; young females most affected; all methods effective.. Keywords: Klebsiella pneumonia, Phenotypic Identification, Urinary Tract Infections (UTIs), Biochemical Tests.
Undergraduate Nursing Students' Knowledge and Attitudes Towards Dementia: A Cross-Sectional Study in Iraq: Pengetahuan dan Sikap Mahasiswa Keperawatan terhadap Demensia: Sebuah Studi Cross-Sectional di Irak Hammooz, Asmaa
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i2.129

Abstract

Background: A reduction in cognitive function, or the ability to think, is typically the outcome of dementia, a disorder that can be caused by a number of diseases that progressively harm the brain and break down nerve cells. Objectives: to evaluate the student's knowledge and attitude regarding dementia and to determine the connection between students' demographic traits and their knowledge and attitude. Methods: Undergraduate nursing students participated in a descriptive cross-sectional study. Nonprobability purposive sampling was chosen for (264) students in the College of Nursing University of al-Qadisiyah. In order to engage in the study, the researcher uses an instrument that is divided into three parts: part one is a demographic data form; part two includes information about dementia form includes (30) items, and part three is attitude toward dementia form (9) items. Results: According to the study's findings, students' overall knowledge rating was fair, with a mean score of 0.58. Conclusion: As the student progresses through the academic stages, their knowledge increases and this knowledge is reflected in their attitudes towards dementia, the study showed that the knowledge of the student in the fourth class with, and in the attitudes. Highlights: Dementia reduces cognitive function due to brain cell damage. Assess nursing students’ dementia knowledge, attitude, and demographic influence. Cross-sectional study of 264 students using structured questionnaires. Keywords: Undergraduate Nursing student, dementia, knowledge, attitude.
A Review on the Relationship Between p53 Gene and Viruses in Endometriosis: Tinjauan tentang Hubungan Antara Gen p53 dan Virus pada Endometriosis Khzal, Alaa Mahdy Obaid
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.130

Abstract

Ten percent of pre-menopausal women suffer from endometriosis which manifests as a chronic inflammatory disorder due to complicated and poorly understood pathogenesis. The relationship between P53 tumor suppressor genes and viral infections as causes of endometriosis needs complete evaluation in research. Studies conducted at the molecular level reveal endometriotic lesions display major P53 expression variations while functional regulation and defensive abilities change from somatic mutations and DNA polymorphisms in addition to epigenetic influences that block tumor-suppression operations. Multiple investigations have established that endometriotic tissues carry human papillomavirus (HPV) Epstein-Barr virus (EBV) and cytomegalovirus (HCMV) viral DNA sequences with varying frequency percentages. The proposed mechanisms study how viral oncoproteins activate P53 pathways in endometriosis development by damaging cell death systems and through their influence on inflammatory processes and genomic instability creation and cell motility changes. The review examines how such biological interactions impact endometriosis diagnosis and treatment options. Currently missing components of known analysis become apparent in this research as it points out needed study techniques for understanding the sophisticated relationship between sun-induced skin damage and Human Papillomavirus infections. Highlights: Endometriosis involves disrupted P53 function due to mutations, polymorphisms, and epigenetics. Viral DNA from HPV, EBV, and HCMV is found in endometriotic tissues, implicating infections in disease progression. Viral oncoproteins may alter P53 pathways, affecting inflammation, cell death, and genomic stability. Keywords: Endometriosis, P53 Tumor Suppressor, Human Papillomavirus, Viral Oncoproteins, Inflammation
Factors Influencing Antenatal Care Services Utilization in Primary Health Care Centers in the Second Sector of Basra City Center: Faktor-faktor yang Mempengaruhi Pemanfaatan Pelayanan Antenatal Care di Puskesmas di Sektor Kedua Pusat Kota Basra Hasan, Marwa Abdul-Satar; Abdul-Qader, Rasha Ahmed; Obaid, Hanadi Lazim
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.131

Abstract

This cross-sectional study was conducted to assess the factors influencing the utilization of ANC services. The total sample consisted of 400 cases with a previous history of pregnancy attending ANC for less than one year, was collected from 15 PHCCs in the second sector of Basra city center, through face-to-face interviews and the use of a questionnaire format during the study period which extended from the beginning of February to the end of July 2018. The results of the present study showed that (31.5%) of the participants’ ages were between 20-25 years old. About two-thirds of the studied women (68.5%) lived in the family home of their husbands; (69.0%) of them had a partner of 1–3. Both studied women, and their husbands had the highest percentage of intermediate education, (28.5%) and (29.5%) respectively. The majority of women (93.7%) were housewives, and most of their husbands were self-employed (67.3%). The highest percentage of participants (66.0%) lived in families composed of seven and above members. There were (89.5%) of women had no history of stillbirth. It was suggested that more government efforts be made to target less educated women and to inform them of the advantages of using antenatal care, this proposal also needs to include their husbands and improve family planning services. Government policy should help increase the spread of the media among mothers. Provide ultrasonic examination services (SONAR) in all primary health care centers and finally, further research should be obtained to include both urban and rural areas. Highlights: Majority were housewives, aged 20–25, with intermediate education level. Most lived in large families, husband's home, with 1–3 children. Recommend education, media access, SONAR services, and broader research coverage. Keywords: Factors, Antenatal Care Services, in Primary Health Care Centers.
Relationship Between Pitx2 Snps with Weights and Body Measurements in Goat: Hubungan Antara Pitx2 Snps dengan Bobot dan Ukuran Tubuh pada Kambing Al-Rubaye, Shaimaa G. A.; Al-Zubaidi , Zainab Hussein Kareem; Redha , Huda Muhanna Redha; Kalaf, Ali Ahmed
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.132

Abstract

This study was conducted at the Ruminant Research Station, affiliated with the Ministry of Agriculture, from December 1, 2021, to March 5, 2022. The objective was to investigate the relationship between single nucleotide polymorphisms (SNPs) in the Paired-like homeodomain transcription factor A (PITX1) gene and growth traits, including body measurements, in goats. A total of 52 female goats were used, including 16 native and 36 Shami goats. DNA sequencing of a 966 bp fragment from the promoter region of the PITX1 gene revealed four mutations. The SNPs G1198A and G1089A exhibited two genotypes: wild-type GG and heterozygous GA, with the mutant homozygous genotype AA not detected. For the C1194T SNP (referred to in the original text as ClYIT), three genotypes were identified: CC (wild), CT (heterozygous), and TT (mutant). Another SNP, G1003A, presented all three genotypes: GG, GA, and AA. The results showed that birth weight and body measurements, such as heart girth and body length, were significantly affected by the C1194T mutation and varied among genotypes. Most other growth traits, however, were not significantly influenced by breed differences. In detail, the highest dam birth weight was observed in the CC genotype (3.23 kg), while the CT genotype was associated with lower neonate birth weight (3.19 kg). The TT genotype (mutant) recorded the highest values for heart girth (83.4 cm) and body length (79.45 cm) in neonates. Furthermore, the G1003A mutation significantly increased dam birth weight, reaching 3.55 kg in individuals with the mutant AA genotype, although it had no significant effect on other growth traits or body dimensions. Highlights: PITX1 SNPs identified: Four mutations were found in the promoter region, notably C1194T and G1003A. Growth traits affected: C1194T and G1003A SNPs significantly influenced birth weight and body measurements. Genotype impact varies: TT and AA genotypes showed superior values in specific growth traits. Keywords: Pitx2, Goat, Snps, Growth, Traits
Comprehensive Midwifery Care for Mrs. F Through Continuity of Care: Asuhan Kebidanan Komprehensif untuk Ny. F Melalui Kesinambungan Asuhan Dewi, Wistri Cendra Mulya; Hanum, Sri Mukhodim Faridah
Indonesian Journal on Health Science and Medicine Vol. 2 No. 2 (2025): Oktober
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i2.134

Abstract

Introduction Comprehensive midwifery care includes pregnancy, childbirth, postpartum, newborns, and family planning (KB). The aim is to reduce the maternal mortality rate (MMR) in Indonesia through Continuity of Care (COC). This research method uses a descriptive method with case studies, collecting data through interviews, observation, physical examination and documentation. The data was analyzed for midwifery care using the SOAP technique. The results of the mother experiencing back pain during pregnancy were overcome with prenatal yoga. The delivery went normally without complications, the baby was born spontaneously weighing 3,200 grams and an Apgar score of 8-9. In the postpartum period, the mother complained of perineal wound pain and with early ambulation the pain was reduced. When the mother has finished postpartum, she is ready to become an IUD birth control acceptor. The conclusion was that no problems or abnormalities were found, so Mrs. F is categorized as normal/physiological. Highlights: Full cycle midwifery care applied from pregnancy to family planning. Non-pharmacological methods like prenatal yoga proved effective. Case supports COC as a model for safe, physiological maternal care. Keywords: Continuity of Care, Midwifery Care, Comprehensive
Continuing Midwifery Care for Pregnancy With Anemia: Asuhan Kebidanan Berkelanjutan untuk Kehamilan dengan Anemia Agustin, Lilik; Hanum, Sri Mukhodim Faridah
Indonesian Journal on Health Science and Medicine Vol. 2 No. 2 (2025): Oktober
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i2.135

Abstract

Anemia during pregnancy is a significant problem, especially in developing countries. Based on data from 2018 Basic Health Research (Riskesdas), the prevalence of anemia in pregnant women was 48.9% which can cause complications such as low birth weight and postpartum bleeding. One of the midwives' efforts to reduce the prevalence rate of pregnant women with anemia is by providing midwifery care (CoC). ) comprehensive/sustainable. This case study aims to describe the results of implementing CoC midwifery care for pregnant women from postpartum to family planning. Method: This case study of midwifery care uses qualitative methods,  where mother D is given care starting from the third trimester of pregnancy, childbirth, newborns, and postpartum to family planning. The CoC midwifery care given to mother D is standard. Results: After providing midwifery care to Mrs. We want all midwives to be able to provide comprehensive and sustainable midwifery services. Highlights: Prevalence of Anemia: Anemia in pregnant women affects 48.9% of cases, leading to complications like low birth weight and postpartum bleeding. CoC Midwifery Care: Comprehensive and sustainable midwifery care (CoC) has shown promise in reducing anemia and improving maternal health outcomes. Implementation and Implications: The study emphasizes the need for all midwives to provide CoC to enhance maternal well-being and reduce anemia-related risks. Keywords: Continue of Care, Pregnancy, Anemia

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