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Juvita Herdianty
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INDONESIA
Strada Journal of Pharmacy
Published by Universitas Strada Indonesia
ISSN : 27763544     EISSN : 27979180     DOI : https://doi.org/10.30994/sjp
Core Subject : Health, Science,
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
The journal includes various fields of pharmaceuticals sciences such as: Pharmacology and Toxicology; Pharmacokinetics; Community and Clinical Pharmacy; Pharmaceutical Chemistry; Pharmaceutical Biology; Pharmaceutics; Pharmaceutical Technology; Biopharmaceutics; Pharmaceutical Microbiology and Biotechnology; Alternative Medicines;
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 6 Documents
 1 
Search results for , issue "Vol. 5 No. 2 (2023): October" : 6 Documents clear
Antibacterial Test Of Telang Flower Extract (Clitorea Ternatea L.) Against Pseudomonas Aeruginosa Luluk Aniqoh Meliana Putri; Chinthia Devientasaria
Strada Journal of Pharmacy Vol. 5 No. 2 (2023): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v5i2.96

Abstract

The butterfly pea flower is a shrub that can grow and live for years (perennial), can reach a height of 5 meters, has fine hair, and is woody at the base, the flower color is bright blue with a yellowish white color in the middle. Butterfly pea flower (Clitoria ternatea L.) is a plant that has long been used in medicine and has been proven to contain alkaloid and flavonoid secondary metabolite compounds which have antibacterial potential. Antibacterials are substances that can interfere with the growth or even kill bacteria by interfering with the metabolism of harmful microbes. The aim of this research was to determine the inhibitory power of telang flower simplicia extract (Clitoria ternatea L.) on the growth of Pseudomonas aeruginosa bacteria. This research aims to test the activity of butterfly pea flowers, namely by maceration using 70% ethanol solvent. For antibacterial testing using the disk diffusion method. Extracts are made in various concentrations of 10%, 20%, 30%. The positive control used was Chloramphenicol. The results of this research were that the average zone of inhibition of butterfly pea flower extract against Pseudomonas aeruginosa bacteria was 1.48 mm at 10% concentration, 2.41 mm at 20% concentration, and 5.70 mm at 30% concentration. These results show that butterfly pea flower extract has antibacterial activity against Pseudomonas aeruginosa bacteria, although the resulting inhibitory power is not strong. At a concentration of 30% butterfly pea flower extract, it has the greatest inhibitory effect on the growth of Pseudomonas aeruginosa bacteria than concentrations of 10% and 20%.
The Effectivity Of Juwet (Syzygium Cumini) Leaf Ethanolic Extract In Rabbit’s Wound Healing Miranda Susanti Putri
Strada Journal of Pharmacy Vol. 5 No. 2 (2023): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v5i2.97

Abstract

Medical plant which has fewer side effects than chemical drugs, is used by people as an alternative to treat wound. Juwet as a medicinal plant has the potential to be developed as a wound healer. The purpose of this study was to determine the ability or activity of juwet leaf extract (Syzygium cumini) in wound healing. The test was carried out using New Zealand rabbits by making wounds on the rabbit's back which were then divided into 5 treatment groups. The treatment group consisted of Group I given aquadestilata, Group II given povidone iodine, Group III given 25% juwet leaf extract, Group IV given 50% juwet leaf extract, and Group V given 75% juwet leaf extract. The results showed that juwet leaf extract (Syzygium cumini) affected wound healing. Average wound diameter consecutively 6,69±1,34, 5,79±2,19, and 4,50±1,70 on day-7. 0,70±0,99, 0,46±0,65, and 0,00±0,00 on the day-10. Based on the results of the research conducted, it can be concluded that juwet leaf extract (Syzygium cumini) has a wound-healing effect on rabbits and the best concentration of juwet leaf extract (Syzygium cumini) for wound-healing activity is 75%.
Activity Testing Of Katuk Leaf Ethyl Acetate Fraction Gel Preparation (Sauropus Androgynus (L.) Merr.) On Healing Wistar Strain White Rat Burns Mintarti; Juvita Herdianty
Strada Journal of Pharmacy Vol. 5 No. 2 (2023): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v5i2.98

Abstract

Burns are a condition of loss or damage to skin tissue due to contact between the skin and a heat source. The ethyl acetate fraction of katuk leaves (Sauropus Androgynus (L.) Merr.) is known to be able to help accelerate the healing process of burns because it contains flavonoids, alkaloids, tannins and saponins. The purpose of this study was to analyze the effect of giving the ethyl acetate fraction of katuk leaves and to find out the best concentration of the fraction in healing burns. This study was a laboratory experimental study using the Post Test Control Only Group Design approach using 25 male white rats divided into 5 groups (each group consisted of 5 rats). The treatment groups were K+ (bioplacenton), K- (base), the ethyl acetate fraction of katuk leaves which consisted of several concentrations, namely F I (5%), F II (10%), F III (20%). The parameters observed were a decrease in the diameter of the burn wound and healing of the skin of the rats. Based on the results of observations of healing of burns, statistically showed a significant difference between groups with a p value <0.05. The best concentration in healing burns on the rat's back was a concentration of 20% with a healing percentage of 83.11%, followed by a concentration of 10% (66.71%), a concentration of 5% (56.00%). The healing activity of burns in the positive control with a healing percentage of 82.35%. So the best burn healing activity was in the ethyl acetate fraction of katuk leaves with a concentration of 20% with a healing percentage of 83.11%.
Testing the Anti-Bacterial Activity of Star Gooseberry Leaves (Souropus Androgynus L) Using the Disc Diffusion Method Using the n-Hexane Fraction Against Propionic Bacterium Acnes Devita Riafinola Andaririt; Ardi Broto
Strada Journal of Pharmacy Vol. 5 No. 2 (2023): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v5i2.100

Abstract

Acne vulgaris or acne, is a common inflammatory condition in the polysebaceous unit that occurs in teenagers and young adults and is characterized by comedones, papules, pustules, and nodules. One of the factors that causes acne is the Propionic bacterium acnes bacteria. One type of plant with antibacterial properties for acne is the Star Gooseberry Leaf plant (Souropus Androgynus L), which contains alkaloids, saponins, tannins, and flavonoids that act as antibacterials. Susanti (2012). This research aimed to obtain data on the antibacterial activity of the compound components contained in the n-hexane fraction of Star Gooseberry Leaves (Souropus Androgynus L) against the Propionic bacterium acnes bacteria, which can be seen from the inhibition zone. The method used was disc diffusion with three groups of control, namely (K(S), K(+), and K(-)). The test bacteria Propionic bacterium acnes, where the Control Sample consists of 4 test concentrations, namely 30 mg, 60 mg, 120 mg, and 240 mg. The positive control used two µg/disc Clindamycin, while the negative control was 2% DMSO. The results of the disc diffusion test of the ethanol fraction of Star Gooseberry Leaves (Souropus Androgynus L) using the disc diffusion method with concentrations of 30 mg/ml and 60 mg/ml did not provide an inhibition zone, the concentration of 120 mg/ml was 11.1 ± 0.10 mm, the concentration was 240 mg/ml was 14.63 ± 0.25 mm. The negative control DMSO 2% did not provide an inhibitory zone diameter, whereas the positive control Clindamycin 2 µg/disk provided an inhibition zone of 25.47 ± 0.70 mm.
The Effect of Maceration and Soxhletation Extraction Methods on The Flavonoid Content of Anting-anting Leaves Extracts (Acalypha indica L.) Using Uv-Vis Spectrophotometry Dita Intan Karisma; Christina Indriasari
Strada Journal of Pharmacy Vol. 5 No. 2 (2023): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v5i2.101

Abstract

Anting-anting (Acalypha indica L) is an annual plant that reaches 30 to 50 cm in height. This plant is often found on mountain slopes, along roadsides, and meadows. Anting-anting leaves (Acalypha indica L) have anti-inflammatory, antibacterial, and antifungal activities. The high content of flavonoids in the leaves of the earrings is efficacious as an antioxidant. This study aims to determine the effect of maceration and soxhletation extraction methods on the levels of flavonoids in the leaves of the anting-anting. This type of research is an experimental study conducted with two extraction methods using 96% ethanol. Qualitative analysis was carried out by color reaction test while quantitative analysis was carried out using a UV-Vis spectrophotometer with the calorimetry method. The standard solution used was quercetin to measure the levels of flavonoids. The results showed that the average level of flavonoids in soxhletation extraction was 5.2266%w/b and in maceration extraction was 5.0084%w/b. The data were tested using the Independent Sample T Test showing a significance value of 0.097 (> 0.05), meaning that there was no significant effect between the maceration and soxhletation extraction methods.
Factors Influencing Satisfaction With Pharmacy Services In Out Patients At DKT Madiun Hospital Hanik Mariana Dewi; Ririn Ernawati; Fidi Setyawan
Strada Journal of Pharmacy Vol. 5 No. 2 (2023): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v5i2.103

Abstract

Patient satisfaction is one of the components used to assess whether a service system is good or bad. The aim of this research is to determine the factors of attitude and waiting time with satisfaction with pharmaceutical services. This type of research is correlation analytic with a cross-sectional approach. The sampling technique was purposive sampling with a sample of 216 patients. Data collection uses questionnaires (attitude and satisfaction) and watches (waiting time). The research results showed that the average waiting time was around 17.49 minutes, as many as 117 (81.9%) respondents from pharmacy staff behaved well and 185 respondents (85.65%) were satisfied with pharmacy services. The Spearman rank statistical test shows that there is a relationship between the officer's attitude and waiting time and satisfaction with pharmaceutical services (p value 0.04 and 0.000 < α = 0.05). Attitudes and waiting times for pharmaceutical services are important factors in improving the quality of pharmaceutical services.

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