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Juvita Herdianty
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INDONESIA
Strada Journal of Pharmacy
Published by Universitas Strada Indonesia
ISSN : 27763544     EISSN : 27979180     DOI : https://doi.org/10.30994/sjp
Core Subject : Health, Science,
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
The journal includes various fields of pharmaceuticals sciences such as: Pharmacology and Toxicology; Pharmacokinetics; Community and Clinical Pharmacy; Pharmaceutical Chemistry; Pharmaceutical Biology; Pharmaceutics; Pharmaceutical Technology; Biopharmaceutics; Pharmaceutical Microbiology and Biotechnology; Alternative Medicines;
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 96 Documents
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Formulation and Physical Quality Evaluation of Cyperus rotundus L. Water Fraction Gel Alfara Derista Felany; Juvita Herdianty; Devita Riafinola Andaririt; Ivan Junius Mesak
Strada Journal of Pharmacy Vol. 8 No. 1 (2026): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v8i1.202

Abstract

The development of topical preparations from natural ingredients requires rigorous physical quality evaluation to ensure their safety, stability, and efficacy. This study aimed to formulate and evaluate the physical quality of a gel preparation containing the water fraction of Cyperus rotundus L. at various concentrations. The water fraction of the rhizome was formulated into gel preparations with concentrations of 5% (F1), 10% (F2), 15% (F3), and 20% (F4) using Carbopol 940 as a gelling agent. The physical quality evaluation included organoleptic tests, homogeneity, pH, spreadability, adhesion, and viscosity. The results showed that all gel formulas met the established physical quality requirements. An increase in the concentration of the water fraction significantly affected the physical characteristics of the preparation, such as a more intense color, as well as an increase in pH, adhesion, and viscosity. All formulas exhibited a pH suitable for the physiological range of the skin (5.53–6.80), good spreadability (5.49–6.77 cm), and adequate adhesion (>2 seconds). It was concluded that the nut grass rhizome water fraction gel has stable and acceptable physical characteristics, making it a potential candidate for further development as a topical preparation.
The Effects of a Low-Carbohydrate Diet on Glycemic Control and Weight in Patients with Type 2 Diabetes Mellitus: Literature Review Julianti, Tri Budi; Putri, Tania; Dewi Lutfania Syahrani; Javier Ammar; Siti Khadijah; Rizki Nur Azmi
Strada Journal of Pharmacy Vol. 8 No. 1 (2026): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v8i1.241

Abstract

Type 2 diabetes mellitus (T2DM) is an increasing global health problem characterized by chronic hyperglycemia due to insulin resistance and/or insulin secretion deficiency. T2DM management often focuses on glycemic control and weight loss through lifestyle interventions, including diet. Low-carbohydrate diets (LCDs) have been one of the most debated and researched dietary interventions, with claims of improving glycemic control and facilitating weight loss. This literature review aims to synthesize the current scientific evidence on the effect of DRK on glycemic control (HbA1c, fasting glucose) and weight in T2DM patients. A systematic review method will be used to identify, evaluate and summarize relevant studies from electronic databases. The review will present key findings from studies, discuss underlying mechanisms, and identify potential benefits, risks, and limitations of DRK. This literature review is expected to provide a more comprehensive understanding for clinical practitioners, patients, and researchers in considering DRK as a T2DM management strategy.
Analysis of the Relationship Between HIV/AIDS Clinical Stage and Opportunistic Infections at Hospital X Devientasari, Chinthia; Selly Septi Fandinata
Strada Journal of Pharmacy Vol. 8 No. 1 (2026): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v8i1.287

Abstract

Opportunistic infections remain a major cause of morbidity and mortality among people living with Human Immunodeficiency Virus (HIV). The progressive decline in immune function increases susceptibility to infections such as tuberculosis, candidiasis, and toxoplasmosis. The World Health Organization (WHO) clinical staging system is widely used to assess HIV disease progression and is often associated with the occurrence of opportunistic infections. This study aimed to analyze the association between HIV clinical stage and opportunistic infections among HIV/AIDS patients at Hospital X. This study employed an observational analytic design with a cross-sectional approach. Data were obtained from medical records of HIV/AIDS patients, with a total sample of 193 patients selected using total sampling. Statistical analyses included univariate and bivariate analyses using the chi-square test. The majority of patients were in clinical stage III (80.3%). The prevalence of opportunistic infections was 14.0%. The results of the chi-square test showed no significant association between clinical stage and opportunistic infections (p = 0.206). Although opportunistic infections were more frequently observed in advanced stages, the relationship was not statistically significant.
Forced Degradation Study of Flavonoid in Portulaca grandiflora extract using Spectrophotometric UV-Vis Cahyani, Erlien Dwi; Amalia Suharyanto, Titah; Fatmadewi Imawati, Maria
Strada Journal of Pharmacy Vol. 8 No. 1 (2026): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v8i1.288

Abstract

Exploration of the effectiveness from magenta purslane herb extract in traditional medicine is still ongoing. Flavonoid is the major compound that allegedly have pharmacology effect in magenta purslane herb extract. To ensure the stability of the flavonoid content in the magenta purslane herb extract, a stability test was carried out using forced degradation. The aim of this study was to determine the effect of forced degradation by acid hydrolysis, alkaline hydrolysis, oxidation and heat substanes on the quercetin content of magenta purslane herb extract using a UV-Vis Spectrophotometer at a wavelength of 424 nm. The results showed in the form of a linear regression equation y=0.0127x + 0.0437 with a value of r2 = 0.9912 with a quercetin content of 10.59 %w/w. It was concluded that statistically there was a significant difference with the decrease content in the acid, base and oxidation forced degradation treatments after 2 consecutive hours of 1,65 %w/w; 3,86 %w/w; 2,38 %w/w whereas no significant reduction was observed under thermal degradation.
The First-Year Effect of Indonesia’s Free Health Screening Program on Drug Planning and Use in Primary Health Centre Wardani, Hanie Kusuma; Adi Wibisono; Janik Kurniawati
Strada Journal of Pharmacy Vol. 8 No. 1 (2026): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v8i1.289

Abstract

Background: The implementation of the Indonesia’s Free Health Screening Program increases healthcare utilization and may alter drug demand in primary healthcare settings. This study aimed to evaluate the conformity between drug planning and actual utilization during Indonesia’s Free Health Screening Program implementation and to assess its implications for drug management efficiency. Methods: This study employed an analytical observational design with a retrospective comparative approach by analyzing Drug Requirement Plans for 2025, drug consumption data from 2023, and actual drug utilization in 2025. Results: The conformity of drugs with the National Formulary was high (88.93–91.89%). However, planning accuracy was suboptimal, with overplanning (50%) and under planning (38%) dominating, and overall item conformity at 81.51%. Increased service utilization due to Indonesia’s Free Health Screening Program significantly influenced changes in drug consumption patterns that were not captured by historical-based planning. Conclusion: The findings indicate that drug planning systems based solely on historical consumption are insufficient in the context of large-scale health programs. Adaptive planning models incorporating real-time data and service utilization trends are required to improve the efficiency of drug management in primary healthcare settings.
Formulation and Determination of Sun Protection Factor (SPF) of Sunscreen Gel Preparations Containing Epigallocatechin Gallate (EGCG) Using the Spectrophotometric Method Oppy Aesaiw
Strada Journal of Pharmacy Vol. 1 No. 1 (2019): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v1i1.123

Abstract

Long-term exposure to the sun causes various kinds of abnormalities in human skin so it requires skin protection from the outside. Sunscreen is a cosmetic therapy that can shield the skin and face against UV radiation, including the potential to induce accelerated ageing, sunburn, and skin cancer. Tea leaf-derived polyphenol compounds, particularly EGCG, have the most potent and plentiful antioxidant action. The objective of this work is to investigate the impact of variations in epigallocatechin gallate (EGCG) levels on the physical properties and effectiveness of sunscreen gel. This study used an experimental design with four EGCG gel formulas (negative control (0%), F1 (0.1%), F2 (0.2%), F3 (0.4%)) and tested with a UV-Vis spectrophotometer with the resulting absorbance calculated using the Mansur formula.The results showed that the SPF value increased with increasing EGCG concentrations (negative control, F1, F2, F3, positive control: 18.94 (moderate), 22.55 (moderate), 29.10 (moderate), 41.58 (high), 48.11 (high)). The highest SPF value on Formulation 3 indicates a high level of sunscreen capability. EGCG gel with a concentration of 0.4% has good physical characteristics (slightly thick texture, odorless, transparent white color, homogeneous, pH 6.57, adhesion 3.30, diffusion 6.36) and the highest SPF value (41.58). The statistical test using Kruskall-Wallis followed by the Man-Whitney test showed a significant difference in a p-value of 0.05.

Page 10 of 10 | Total Record : 96

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