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Juvita Herdianty
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INDONESIA
Strada Journal of Pharmacy
Published by Universitas Strada Indonesia
ISSN : 27763544     EISSN : 27979180     DOI : https://doi.org/10.30994/sjp
Core Subject : Health, Science,
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
The journal includes various fields of pharmaceuticals sciences such as: Pharmacology and Toxicology; Pharmacokinetics; Community and Clinical Pharmacy; Pharmaceutical Chemistry; Pharmaceutical Biology; Pharmaceutics; Pharmaceutical Technology; Biopharmaceutics; Pharmaceutical Microbiology and Biotechnology; Alternative Medicines;
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 83 Documents
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Formulation And Evaluation Quality Physique Preparation Lip Tint Extract Sweet Potato ( Ipomoea batatas (L.) Lamb) with Extract Dragon Fruit ( Hylocereus polyrhizus ) As a Natural Lip Pigment Poppy Martha Lowra; Devita Riafinola Andaririt; Sri Rahayu Dwi P; Ivan Junius Mesak
Strada Journal of Pharmacy Vol. 6 No. 2 (2024): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i2.147

Abstract

ABSTRACT Introduction: Lip Tint is one of the stock cosmetics that have role in give role decorative on lip pigment coloring . The rise of use dye synthesis in preparation dangerous liptint​ for lips so use material Sweet Potato Nature ( Ipomoea batatas) (L.) Lamb) which is combined Dragon Fruit ( Hylocereus polyrhizus ) can replace dye synthesis in the preparation. Purpose : to know difference concentration extract sweet potato jalar ( ipomoea Batatas (l.) lamb) combination extract fruit dragon ( hylocereus polyrhizus ) against evaluation quality physical . Method: research experimental formulation stock lip tint with using sweet potatoes concentrations of 10%, 20% and 30% combined fruit dragon 6%. Substance color natural contained in sweet potatoes are keratinoids and in fruit dragon that is anthocyanin . Results: In the study This show that stock lip tint sweet potato concentrations of 10, 20 and 30% combined fruit dragon 6%. Yield liptint that has texture , color , aroma, and Power stickiness , power spread , good viscosity . The pH of the preparation is at a value of 8 but No cause irritation to the skin . The results of the data analysis were obtained No there is significant difference in power test spread , power test adhesion and viscosity test and occurs significant differences in pH and FIII were most preferred by respondents . Conclusion: Research This own conclusion concentration sweet potato extract and extract fruit dragon influence results testing quality physique preparation . Quality test results physique show that stock lip tint with sweet potato concentration of 30% (F III) provides results best .
Antibacterial Activity Test of Combination of Chitosan and Ethanol Extract of Cocoa Leaves (Theobroma Cacao L.) Against Salmonella Typhi Bacteria Saifullah Al Fahmi; Luluk Aniqoh Meliana Putri; Ivan Junius Mesak; Juvita Herdianty
Strada Journal of Pharmacy Vol. 6 No. 2 (2024): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i2.148

Abstract

Introduction:Typhoid fever is a systemic infectious disease caused by the bacterium Salmonella typhi. The increasing antibiotic resistance of Salmonella typhi has spurred interest in natural antibacterial agents. This study examines the antibacterial activity of a combination of chitosan and ethanol extract of cocoa leaves (Theobroma cacao L.) against Salmonella typhi. Methods: The research involved extracting cocoa leaves using ethanol and combining the extract with chitosan. The antibacterial activity was evaluated using the well diffusion method on Salmonella typhi. The combination of chitosan and cocoa leaf extract was tested at various concentrations, and chloramphenicol was used as a positive control. Results: The combination of chitosan and cocoa leaf extract showed significant antibacterial activity, with the best results obtained at higher concentrations. The zone of inhibition for the combination at 600 ppm was comparable to that of the positive control of chloramphenicol. Conclusion: The study suggests that the combination of chitosan and cocoa leaf extract has the potential to be developed as an alternative treatment for typhoid fever, particularly against antibiotic-resistant strains of Salmonella typhi.
Fomulation And Physical Quality Testing Of A Scrub Gel With Ethanol (70%) Extract Of Pineapple Core (Ananas comosus (L.) Merr.) Rizka Nursilah Ode; Juvita Herdianty; Sri Rahayu Dwi P.; Arif Wijayanto
Strada Journal of Pharmacy Vol. 6 No. 2 (2024): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i2.150

Abstract

Scrubs are widely used in cosmetic care, primarily for exfoliation to remove dead skin cells. This study used a 70% ethanol extract from pineapple cores (Ananas comosus (L.) Merr.), which contains active compounds such as bromelain, flavonoids, and saponins. These compounds were formulated into a scrub gel that potentially benefits skin health, especially in exfoliation. The aim of this study was to evaluate good physical quality characteristics, including organoleptic properties, homogeneity, pH, viscosity, adhesion, and spreadability, based on varying concentrations of ethanol extract from pineapple cores. This research employed a true experimental method with a post-test only design to determine the best physical quality of scrub gel formulations containing pineapple core extract (Ananas comosus (L.) Merr.) at three extract concentrations: 3%, 5%, and 10%. The physical quality evaluation of the scrub gel, including organoleptic properties, homogeneity, viscosity, adhesion, and spreadability, showed good results and met the standards. However, the pH testing results for the three formulations did not meet the standards, as they were relatively neutral to slightly acidic (6.48-7.58). The hedonic test results indicated that Formulation 2 (5%) received the highest ratings in terms of aroma and texture, while Formulation 1 (3%) and Formulation 3 (10%) also showed a tendency to be preferred in certain aspects, particularly in terms of color and texture. The Kruskal-Wallis test followed by the Mann-Whitney test showed significant differences in pH, viscosity, and adhesion (p-value: 0.46-0.05 ≤ 0.05). Meanwhile, the One-Way ANOVA test on spreadability showed a very significant difference in spreadability, with Formulation 3 and the negative control having the highest spreadability (p-value <0.005). The concentration of pineapple core extract affects the physical and sensory characteristics of the scrub gel, with the addition of active pineapple core extract at a concentration starting from 3% already showing good physical characteristics.
Analysis of Patient Satisfaction with Pharmaceutical Services at Pharmacy Faeyza Farma Banyuwangi Regency Rizalina Fajar Inzani; Fidi Setyawan; Hanik Mariana Dewi; Janik Kurniawati
Strada Journal of Pharmacy Vol. 3 No. 2 (2021): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v3i2.151

Abstract

Pharmaceutical services are an integral part of the health system and are essential in realizing quality health for the community. This study used a quantitative descriptive approach to provide an objective picture of the condition of pharmaceutical services at Faeyza Farma Pharmacy in Banyuwangi Regency. Data were collected through questionnaires distributed to patients and families of patients who visited the pharmacy. Sampling was systematically randomized to ensure the representativeness of the population under study. The results showed that most patients were satisfied with pharmaceutical services at Faeyza Farma Pharmacy, with an average value of the gap between expectations and a tiny realization of -0.06. Based on patient satisfaction standards based on five dimensions, most patients are satisfied with the services at the Faeyza Farma Pharmacy, with an average satisfaction percentage of 80%, which is in the satisfied category. Based on the Importance and Performance Matrix Analysis, all question items in the questionnaire related to the five dimensions of pharmaceutical services at the Faeyza Farma Pharmacy are in quadrant II, which indicates that the service is good and needs to be maintained.
Antibacterial Activity Test of Ethanol Extract of Spoon Leaves (Plantago major. L) Against Pseudomonas aeruginosa Ira Jayani
Strada Journal of Pharmacy Vol. 2 No. 1 (2020): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v2i1.153

Abstract

Typhoid is a bacterial infection disease of Pseudomonas aeruginosa. The irrationality of antibiotics against Pseudomonas aeruginosa is reported to trigger bacterial resistance, thus requiring an alternative antibacterial agent against typhoid. The diversity of Indonesian medicinal plants is still promising as a potential source of antibacterial agent, including sendok leaf. This study was aimed to determine antibacterial activity of ethanol extract of kacapiring leaves and its fractions against Pseudomonas aeruginosa. Subsequent fractionation was carried out using liquid-liquid partition method to obtain n-hexane, ethyl acetate, and etanol-water fractions. Antibacterial test was carried out using disk diffusion method to determine the diameter of inhibitory zone at concentrations of 10%, 15%, 20%, and 25%. The best antibacterial activity was revealed by residue fraction of 25% with inhibition zone diameter of 9,5 mm, respectively. Sendok have moderate antibacterial activity against Pseudomonas aeruginosa.
IN SILICO STUDY OF THE POTENTIAL OF GAMBIR LEAF CATECIN COMPOUNDS (Camellia sinensis L.) AS ANTI-BACTERIAL AGAINST Mycobacterium tuberculosis IN InHA Riska Luthfiani
Strada Journal of Pharmacy Vol. 1 No. 1 (2019): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v1i1.154

Abstract

Isoniazid is an anti-tuberculosis pro-drug by inhibiting mycolic acid in bacterial cell walls which requires activation by inhA and the presence of mutations in the Kat-G gene increases resistance to isoniazid. The disadvantages is that high humidity can cause bacteria to grow quickly. Pathogenic bacteria are one of the causes of infection, both gram-positive bacteria and gram-negative bacteria. One of the diseases caused by bacteria is tuberculosis, which is caused by Mycobacterium tuberculosis. The four compounds of the catechin group from gambir plants, namely Epikatekin (EC), Epigallo catechin (EGC), Epikatekin gallate (ECG), and Epigallokatekin gallate (EGCG), three of which meet the criteria of Lipinski's five laws, namely in EC, ECG and EGC with one violation, namely Hydrogen Bond Donor> 5 where Lipinski's criteria for compounds are said to be good if HBD < 5
Evaluation Of Fulfillment Of Pharmacy Service Standards In Clinical Pharmacy Services For Analgesic Drugs At Wijaya Pharmacy Health Of Kediri District Titis Surya A; Fidi Setyawan; Adi Wibisono; Chinthia Devientasari
Strada Journal of Pharmacy Vol. 6 No. 2 (2024): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i2.161

Abstract

Pharmaceutical services are services related to pharmaceutical preparations such as drugs recommended for the treatment of improving the quality of life of patients. The government has made efforts to improve health services, including the construction of various health facilities such as pharmacies. In accordance with PMK Number 73 of 2016 concerning Standards of Clinical Pharmacy Services in Pharmacies, this study was conducted with the aim of determining the fulfillment of pharmaceutical service standards in clinical pharmacy services for analgesic drugs at the Wijaya Sehat Pharmacy, Kediri Regency, including clinical pharmacy services such as PIS, Counseling, DTM, and MDSE, along with the Attitudes and Behavior of pharmacists during service through patient or respondent perceptions. The research method uses a quantitative method with a cross-sectional research design, the tool used to conduct this study is a questionnaire using a Likert scale 1-4 (strongly agree, agree, disagree, strongly disagree). Sampling using accidental sampling technique of 120 respondents who purchased analgesic drugs. Instrument testing was conducted for validity and reliability in different places before conducting the study. The results obtained were that pharmaceutical services at Wijaya Sehat Pharmacy still carried out 2 services, namely PIS and Counseling, while DTM and MDSE had not been implemented due to limited human resources, there were no complaints related to Side Effects of Drugs (SED), there were no diseases that required DTM, and patients had a comfortable perception during service because pharmacists were polite and
Analysis of Salicylic Acid in Biological Fluids (Serosal) Using Uv-Vis Spectrophotometry Chintia D; Resca S.S.; Anggra I.N.A
Strada Journal of Pharmacy Vol. 6 No. 1 (2024): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i1.163

Abstract

Pharmacokinetics is an aspect of pharmacology that covers the fate of drugs in the body, namely absorption, distribution, metabolism, and excretion (ADME). Overall, bioavailability shows the kinetics and comparison of the levels of active substances that reach the bloodstream to the amount of drug given. Method validation is carried out to determine that the analytical method used is accurate, specific, reproducible, and resistant to the analyte to be analyzed. An analysis model must be validated to verify that its performance parameters are sufficient to overcome the analysis problem. The research method used is included in observational experimental research. Observational experimental research is research conducted by analyzing a compound and testing it. The results of this study obtained a standard curve value of Y = 0.006x + 3.401, r2 = 0.334 with λmax 329 nm. Recovery (% recovery) in the study, the average recovery value of the concentration was 200μg/mL (118.8%); 150 μg/mL (72.1%); 100 μg/mL (131.5%). Systemic error of series concentration 200 μg/mL (-18.8%); 150 μg/mL (278%); 100 μg/mL (-31.5%). Based on the study, validation testing of the method with further precision and accuracy is needed.
Effectiveness of Garlic (Allium Sativum L.) Skin Extract Cream on the Healing of Rabbit (Orytolagus Cuniculus) Burn Wounds Ivan Julianus Mesak; Icho Erinda Timur; Tetty Eka Sugiyanto
Strada Journal of Pharmacy Vol. 5 No. 1 (2023): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v5i1.164

Abstract

Garlic Tuber Skin (Allium sativum L.) contains flavonoids, alkaloids, saponins and tannins. The content of flavonoids, alkaloids, saponins and tannins contained in garlic bulb skin can have an effect on healing skin that has damaged cell tissue due to burns. This study aims to make a cream formulation of garlic bulb peel extract (Allium sativum L.) with various concentrations of 10%, 15% and 20% using adeps lanae cream base, liquid paraffin, stearic acid for the oil phase and TEA, nipagin for the oil phase. water which was then tested for its effectiveness in healing burns in rabbits (Orytolagus cuniculus). The negative control used cream base and the positive control used MEBO cream. The effectiveness test on burns was carried out on the back of a rabbit with a diameter of 1 cm. The wound was smeared twice a day with lidocaine cream and the healing effect was observed for 14 days. The results showed that from the 1st to the 14th day of observation, the burn wound decreased in diameter. It was concluded that cream concentrations of garlic bulb peel extract 10%, 15% and 20% had the fastest healing and wound healing effect on cream with a concentration of 20%.
Analysis of Free Fatty Acid Contents (As Acid Laurat) Pure Coconut Oil (Virgin Coconut Oil /VCO) which Circulates in Kediri City Sri Rahayu Dwi Purnaningtyas
Strada Journal of Pharmacy Vol. 4 No. 2 (2022): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v4i2.167

Abstract

Pure Coconut Oil (Virgin Coconut Oil / VCO) is a vegetable oil that contains medium chain saturated fatty acids. The medium-chain saturated fatty acid that has the highest content in virgin coconut oil is lauric acid. Lauric acid can be directly absorbed by the liver and used as an energy source. This study aims to determine the levels of free fatty acids (as lauric acid) in virgin coconut oil (Virgin Coconut Oil/VCO) according to SNI Standard 7381: 2008. The samples used in this study were pure coconut oil from various brands on the market in Indonesia. Kediri city. This study used an alkalimetry method to identify the free fatty acid levels in the sample. From the results of the analysis on 5 (five) brands of virgin coconut oil, it was found that all samples met the requirements of SNI 7381: 2008 which is a maximum of 0.2%. The results of the analysis of the levels of free fatty acids as lauric acid, the largest 0.1988% and the smallest 0.1643% according to the requirements of SNI.

Page 7 of 9 | Total Record : 83

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