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Jurnal Widya Medika
Published by Universitas Katolik Widya Mandala Surabaya
ISSN : 23380373     EISSN : 26232723     DOI : https://doi.org/10.33508/jwm
Core Subject : Health,
Medicine & Pharmacology
Jurnal Widya Medika is the official publication media of Widya Mandala Surabaya Catholic University, Faculty of Medicine. Jurnal Widya Medika publishes original research articles, case reports, and literature reviews from scientists of various medical education and research institutions, including select scientific works from medical students. All articles published had undergone plagiarism checks, editorial review by the editorial board, and peer review by experts from their respective fields in order to maintain the high standard of articles published in Jurnal Widya Medika.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 184 Documents
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THE EFFECTS OF PINUS MASSONIANA (PINE POLLEN) AS ADJUVANT THERAPY ON LEUKOCYTES, T LYMPHOCYTES, C-REACTIVE PROTEIN, AND D-DIMERS IN HOSPITALIZED COVID-19 PATIENTS Prettysun Ang Melow; Handi Suyono; Maria Magdalena Ano Djoka; Agata Christi Palupi; Steven Hermantoputra; Anton Hariadi; Yudita Wulandari; Sri Purwaningsih
JURNAL WIDYA MEDIKA Vol. 8 No. 1 (2022): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v8i1.3626

Abstract

Introduction: SARS-CoV-2 infection has caused the Corona Virus Disease-19 (COVID-19) pandemic until present day. Pine pollen has been known and used as a medicine and has benefits for immunity. Aim: To determine the effects of Pinus massoniana (pine pollen) as an adjuvant on leukocytes count, T lymphocytes (CD4, CD8) count, plasma C-reactive protein level, plasma D-dimer level in hospitalized COVID-19 patients with moderate-severe clinical manifestation. Materials and Method: We used a double blind pretest-posttest control group design, with 2 groups, namely control (placebo) and treatment. The subjects were selected by simple random sampling, male and female patients aged 20-60 years. Peripheral blood samples were taken before and after treatment. Patients were given pine pollen or placebo 3 x 4 capsules (3 g / day) for 7 days. Data were analyzed by SPSS 23.0 t-test with significant value of p < 0.05. Results: The patients of treatment group were 16 people (13 male, 3 female), average age 46,25 years and control 13 people (10 male, 3 female), average age 47,92 years. The leukocytes count increased not significantly in the treatment group (p=0.499; 8.03%) while control increased significantly (p=0.027; 36.42%). The leukocytes count of control was 4,5 times greater than treatment group. The CD4 count increased significantly in the treatment group (p=0.004; 73.44%) and control (p=0.048; 28.97%), and the it was 2,5 times greater than control. The CD8 count increased significantly in the treatment group (p=0.005; 72.90%) and control (p=0.033; 34.66%), and it was 2,1 times greater than control. CRP levels were significantly reduced in the treatment group (p=0.001; 71.61%) and control (p=0.001; 78.13%). D-dimer levels decreased significantly in the treatment group (p=0.048), while the control increased but not significantly (p=0.200). The D-dimer level in the treatment group decreased by 37.93%, while the control increased by 43.70%. Conclusion: Further research is still needed to explore the effect of pine pollen on cellular immunity which in this case is T lymphocytes, especially CD4 and CD8, and hemostasis (coagulation) especially D-dimer. Pine pollen is beneficial for immune modulation in COVID-19 patients.
THE EFFECT OF CINNAMALDEHYDE MEMBRANE APPLICATION ON THE NUMBER OF MACROPHAGES ON THE INFLAMMATION PROCESS OF LABIAL ULCUS OF WISTAR RATS Chrisdina Puspita Sari; Nunuk Purwanti; Ika Dewi Ana
JURNAL WIDYA MEDIKA Vol. 8 No. 1 (2022): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v8i1.3712

Abstract

Introduction: Macrophage is the inflammatory cell that dominates the chronic inflammation. Macrophage plays an important role in phagocytic process and secretion of chemical mediators in the early stage of inflammation. Cinnamaldehyde is the major constituent of cinnamon plant has an anti-inflammatory effect. Cinnamaldehyde can be delivered by membrane-shaped hydrogel polymer made from gelatin to maximize its anti-inflammatory effect. Aim: The objective of this study was to investigate the effect of cinnamaldehyde membrane on the macrophage numbers on the labial ulcer of Wistar rats. Methods: Thirty Wistar Rats were divided into 5 groups, 4 groups as treatment and 1 group as a control. An injury of the labial mucosa of Wistar Rat was made by the application of acetic acid glacial on the labial mucosal surface. The cinnamaldehyde membrane 1%, 4%, K-diclofenac membrane, and DMSO membrane were applied on the wound of the treatment groups, while the DMSO was applied on the control group at one day after injury. Three rats from each group were sacrificed on the 3rd and 6th day. The ulcerative mucosal tissues were collected and processed for histological preparation with Hematoksilin Eosin (HE) staining. The numbers of macrophage was counted in 6 fields using trinocular microscope. The data were analyzed using Two-way Analysis of Variance (Two-way Anova). Result: The result of Two-way Anova showed that there were significance differences between the treatment and control groups, so were the interaction of the treatment and the day. Conclusion: The application of cinnamaldehyde membrane has an effect on the numbers of macrophage on the labial ulcer of Wistar Rats.
BODY IMAGE WITH EATING PATTERNS STUDENTS STIKES SANTA ELISABETH MEDAN Nagoklan Simbolon; Pomarida Simbolon
JURNAL WIDYA MEDIKA Vol. 8 No. 2 (2022): October
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v8i2.3748

Abstract

Background: Students are individual figures who are in the process of changing from childhood to adulthood. These changes occur both physically, biologically as well as psychologically and socially. These physical changes depend on a person's diet which will build a body image or body image to a good or bad direction. This happened at STIKes Santa Elisabeth Medan, namely the eating pattern of 30% of STIKes students was not good. The purpose of the study was to determine the relationship between body image and diet in students at STIKes Santa Elisabeth Medan. Methods: the method used is descriptive analytic by using a cross sectional approach. The sample in this study amounted to 110 people with simple random sampling technique. Data analysis with chi-square test. Results: the results showed that the majority of respondents' body image was negative (71, 8%) and the majority of respondents' eating patterns are sufficient (54.6%). The results of the chi-square statistical test obtained p-value = 0.001 (p < 0.05), so there is a relationship between body image and diet in STIKes Santa Elisabeth Medan students. It is hoped that the campus will provide counseling to students so that body image is controlled.
ASSOCIATION BETWEEN HEART RATE VARIABILITY AND BLOOD PRESSURE IN ELDERLY WORKER Kartika, Ronald Winardi; Susanti, Yosephin Sri; Winata, Susanti Dewi
JURNAL WIDYA MEDIKA Vol. 10 No. 1 (2024): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v10i1.3765

Abstract

Life expectancy increases along with improving health. A good healthy life as an impact that there are still many workers in old age who are still needed. The effect of age and work environment will affect the normal range of time-domain heart rate variability (HRV) in older worker. Heart rate variability test might detect autonomic nervous system influenced by blood pressure level, stress, and working environment. A low HRV value is considered an independent marker of risk of death. However, age-related decline in HRV may limit its predictive value, especially in older workers. It was found that the decrease in HRV decreased with age and length of service. The elevation of HRV at specific wavelengths was correlated with the blood pressure values of hypertension patients; however, in the uncontrolled hypertensive group, the values of SDNN, SDANN, ASDNN, VLF, LF (indicating sympathovagal balance), and HF were significantly lower.
FACTORS ASSOCIATED WITH THE PREVALENCE OF SARCOPENIA IN ELDERLY UNIVERSITY WORKERS Ronald Winardi Kartika; Yosephin Sri Susanti; Susanti Dewi Winata
JURNAL WIDYA MEDIKA Vol. 9 No. 2 (2023): October
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v9i2.3767

Abstract

The most common cause of sarcopenia is a lack of physical activity throughout the day. In addition, there are also other possibilities that could be the cause of this loss of muscle mass, namely: Decreased levels of certain hormones related to muscle. University workers who experience retirement often experience sarcopenia, because when they are still active, university workers are less active and have less protein intake. For this reason, it is necessary to pay attention to the activities of university workers while they are still active and productive at work
RELATIONSHIP OF EPICARDIAL ADIPOSE TISSUE THICKNESS AND NEUTROPHIL TO LYMPHOCYTE RATIO WITH CORONARY LESION SEVERITY IN STABLE CORONARY HEART DISEASE Darwin Indra; Lucia Panda; Edmond Jim; Dewi U. Djafar; Victor G. X. Rooroh; Monique P. F. Rotty
JURNAL WIDYA MEDIKA Vol. 8 No. 1 (2022): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v8i1.3825

Abstract

Introduction: Stable angina pectoris (SAP) is the one of the leading causes of death in men and women from every major ethnic group. Several studies have shown that the neutrophil to lymphocyte ratio (NLR) is a systemic inflammatory marker associated with cardiovascular events. EAT has been considered to have an important role in cardiovascular physiology and pathogenesis. This study aimed to investigate the relationship of EAT thickness and NLR with coronary lesion severity in patients with stable coronary heart disease. Methods: This study was a cross-sectional study conducted at Department of Cardiology and Vascular of Kandou General Hospital, Manado, North Sulawesi, Indonesia, from May to August 2019. The population were patients with SAP who underwent coronary angiography procedures. The relationship between the EAT and NLR and the SYNTAX score were evaluated on a bivariate and multivariate level. Results: A significant linear relationship between EAT thickness and SYNTAX score was found (Pearson r = 0.32; p = 0.014). In addition, after controlling for sex and NLR, the correlation between EAT thickness and SYNTAX score increased to almost 0.7 points for each millimeter increase in EAT (95% CI 3.45 - 10.25; p
CITOMEGALOVIRUS (CMV) ENCEPHALITIS: A CASE REPORT Meryana, Meryana
JURNAL WIDYA MEDIKA Vol. 8 No. 1 (2022): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v8i1.3826

Abstract

Encephalitis results from an inflammatory process in the brain which can be caused by infection, post infection or non-infection processes. The most common etiology is infection, especially by virus. Encephalitis is usually followed by diffuse and or focal neuropsychology dysfunctions of brain and meninges (meningoencephalitis). Symptoms of encephalitis are photophobia, headache or neck stiffness, focal neurological deficits, seizure, decrease of consciousness, behavior disorders, and aphasia. However, some patients may not show predominant neruological deficits or even asymptomatic. Inaccuracy to diagnose the etiology promptly can cause morbidity and mortality due to this disease. The author reports one case of citomegalovirus (CMV) encephalitis with mild symptoms. In this case, a 36-year old man with symptoms of mild fever and mild headache was consulted by an internist to neurologist, because internal examinations couldn’t find the etiology of the patient’s symptoms. The results of laboratory examinations of NS-1, Dengue IgM and IgG Dengue, Salmonella IgM and IgD, hepatitis screening tests, and chest X-ray examination showed normal results. Brain MRI with contrast then was performed with normal result. Cerebrospinal fluid (CSF) analysis showed pleiocytosis, predominantly mononuclear cells. Diagnosis of CMV encephalitis was established by examination of CMV PCR (Polymerase Chain Reaction) of CSF that was positive. The patient was then treated with antiviral agent Gansiklovir 5 mg/kg every 12 hours for 14 days. On the third day of therapy, the patients had been free of symptoms. The patient was discharged form the hospital in good condition.
ACUTE DISSEMINATED ENCEPHALOMYELITIS FOLLOWING A DIPHTHERIA-PERTUSSIS-TETANUS VACCINATION: A CASE REPORT Stephanie Angela Prijanto; Tikto Wahyono; Pipit Soesilowati
JURNAL WIDYA MEDIKA Vol. 8 No. 1 (2022): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v8i1.3827

Abstract

Introduction: Acute disseminated encephalomyelitis (ADEM) is a rare, acute progressive autoimmune disease that occurs in the brain and spinal cord, in response to infection or immunization. Myelin autoantigens could share similar antigenic determinants with a pathogen and cross-react with a human’s antibody, causing demyelination of the nerve sheath. Identifying ADEM is essential to treat the patient and reduce any sequelae. Case description: An 11-year-old male was brought to the ER with one day of weakness of the face and the left side of the body. Along with that, the patient vomited, complained of headache and fever. One day prior, the patient received a Diphtheria-Pertussis-Tetanus Vaccination at his elementary school. A head computer tomography (CT) scan with contrast was done and showed multiple hypodense lesions in the bilateral internal capsule, bilateral lateral periventricular, subcortex of the right frontal lobe, and right cerebellum, with suspicion of ADEM. Discussion: There were many clinical signs of patients with ADEM, depending on the lesion. Brain and cerebellar lesions can cause irritability, confusion, coma, incoordination, and gait problems. Spine lesions can cause numbness and paralysis of the limbs. Lesions in the cranial nerve can cause dysarthria, blurry vision, double vision, and facial weakness. Conclusion: The prognosis for ADEM is good and often has improvement within a month. However, some patients need to undergo supportive therapy as appropriate. Further follow-up needs to be done to evaluate the disease progression, as ADEM may be manifesting as Multiphasic ADEM or any other demyelinating disease.
PANCOAST TUMOR : A CASE REPORT Epriyanto Tri Darmadi; Ivan Tjokrowinoto
JURNAL WIDYA MEDIKA Vol. 8 No. 2 (2022): October
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v8i2.3864

Abstract

Introduction: Pancoast tumor, or superior sulcus tumor, is defined as a tumor that grows on the thoracic inlet or grows on a pleuropulmonary peak that is found beyond the initial cost. These tumors may invade upper ribs, muscle, vertebral, subclavian vessels, the inferior portion of brachial plexus, sympathetic nervous system, and stellate ganglion. Pancoast tumors are mostly caused by non-small cell lung cancer. Case description: A 59-year-old man came to the emergency room with complaints about a lack of pain in his left chest. Other symptoms reported by the patient include chest discomfort, stiffness, pain rising and subsiding on the left arm that may spread back and forth, and weight loss. Chest CT Scan with contrast shows a heterogeneous mass appears at the tip of the left lung, pushing the upper lobe of the left lung, bronchiectasis at the lower lobe of the left lung, destruction of the left coastal bones 1, 2, and 3, and tracheobronchial supero-inferior lymphadenopathy. Anatomical pathology results round cell tumors favor adenocarcinoma with poorly differentiated metastasis Discussion: Diagnosis of Pancoast tumor is supported by patient symptoms, imaging results, and biopsies. This patient's complaints and symptoms are unusual, leading doctors to believe that the cause is not a Pancoast tumor. Keep in mind that Pancoast Tumors aren't the only thing that can cause Pancoast syndrome, though they are the most common. The results of this patient's biopsy rule out other causes of Pancoast tumor and are consistent with the cause of Pancoast tumors, namely adenocarcinoma, a type of non-small cell lung cancer. Conclusion: Chronic and progressive complaints and unintentional weight loss become "red flags" that may indicate the start of the malignancy process. A good clinical approach can help detect these tumors early, improving the patient's prognosis.
CLINICIAN’S VIEW ON THE IMPORTANCE OF RADIOLOGY REPORT IN THEIR DAILY PRACTICE Astawa, Gregorius Adista Enrico; Meilani, Yohana F. Cahya Palupi
JURNAL WIDYA MEDIKA Vol. 8 No. 2 (2022): October
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v8i2.3952

Abstract

Bacground: A radiology report is a medicolegal document and formal communication between a radiology radiologist and referring physician/clinician. The failure of radiologists to communicate good quality reports often occurs in the process of patient diagnosis. This study aims to determine the clinician’s view on the importance of radiology reports in patient management of their daily practice in Papua and West Papua. Method: One hundred and eighty-four general practitioners and internship doctors answered an online questionnaire distributed randomly. Forty-five indicators assessed the accessibility to radiology reports, the importance of radiology reports, attached clinical information, clinician satisfaction, structure, and content of radiology reports. This study has seven variables with six paths tested using the Structural Equation Modeling (PLS-SEM) analysis method based on Partial Least Squares based using SmartPLS. Result: Data analysis showed that radiology reports, clinical information, clinician satisfaction, and structure of radiology reports had a positive and significant effect on patient management, while accessibility and content of radiology reports had no significant effect on patient management. Conclusion: Clinicians thought the radiology report was an important medical document that has a role in patient management of their daily practice.

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