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Jurnal Pharmactive
Published by Institut Teknologi dan Kesehatan Bintang Persada
ISSN : -     EISSN : 28293444     DOI : -
Core Subject : Education, Social,
Environmental Science Other
Initially LPPM Institut Teknologi dan Kesehatan Bintang Persada published a journal that aimed to accommodate campus internal lecturers at Institut Teknologi dan Kesehatan Bintang Persada in publishing scientific papers. Because the lecturers who want to carry out publications come from various fields of science, such as Clinical andCommunity Pharmacy, Pharmaceutical Analysis, Herbal Medicine, Pharmaceutical Techology, Management of Pharmacy, etc. the published journal seems not to have a clear focus area (accepting all types of articles). In addition, efforts to improve journal management by LPPM, as well as accreditation demands for scientific periodicals / journals determined by related parties. FOCUS AND SCOPE Clinical and Community Pharmacy Pharmaceutical Analysis Herbal Medicine Pharmaceutical Technology Management of Pharmacy
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 48 Documents
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EVALUASI PENGGUNAAN ANTIBIOTIK PADA PASIEN ISPA PEDIATRI DI INSTALASI RAWAT INAP PADA SALAH SATU RUMAH SAKIT KOTA TEGAL PERIODE 2024 Apriliani, Amanda Afni
Journal Pharmactive Vol. 4 No. 1 (2025): Jurnal Pharmactive April
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

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Abstract

Acute Respiratory Infections (ARI) are among the most common infectious diseases in pediatric patients and remain a major cause of morbidity and mortality worldwide. The increase in ARI cases is directly associated with the high use of antibiotics, which can contribute to bacterial resistance if not aligned with proper therapeutic guidelines. Therefore, this study aimed to evaluate the pattern and rationality of antibiotic use in pediatric patients with ARI in the hospital's inpatient ward in Tegal City during the 2024 period. This study employed an observational method with a retrospective approach. The evaluation of antibiotic use was conducted using the Gyssens method to determine the appropriateness of use based on rationality categories. The results showed that the most commonly used antibiotics were ceftriaxone (65.5%), cefotaxime (16.2%), and amoxicillin (7.14%). Analysis using the Gyssens method indicated that in 74.02% of cases, more effective antibiotics were available; in 1.94% of cases, more affordable options could have been used; in 18.8% of cases, antibiotics were used for too short a duration; and in 3.24% of cases, incorrect dosages were prescribed. Only 1.94% of cases involved rational antibiotic use. In conclusion, based on the Gyssens method, 98.05% of antibiotic use in this study was considered irrational, while only 1.94% was deemed rational.
HUBUNGAN DATA DEMOGRAFI TERHADAP PENGETAHUAN TENTANG ANTIBIOTIK hasan2002
Journal Pharmactive Vol. 4 No. 1 (2025): Jurnal Pharmactive April
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

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Abstract

The irrational use of antibiotics is the main cause of increasing bacterial resistance in the community. Demographic data is thought to influence antibiotic use behavior. This study aims to determine the relationship between demographic data and knowledge about antibiotics in the community. This is a quantitative study with a cross-sectional design. A sample of 218 respondents was selected using convenience sampling and snowball sampling techniques. Data were collected through a questionnaire measuring the level of knowledge about antibiotics and demographic data of the respondents. Data analysis was performed using univariate and bivariate analysis with the Spearman Rank test. Demographic factors such as educational level were significantly associated with knowledge levels and behavior (p < 0.05). Knowledge levels significantly influenced antibiotic usage behavior. Demographic characteristics also play a role in shaping rational antibiotic usage behavior in the community.
the Pengaruh Kualitas Pelayanan Kefarmasian Terhadap Kepuasan Pasien Di Apotek Desa Blahkiuh: Pengaruh Kualitas Pelayanan Kefarmasian Terhadap Kepuasan Pasien Di Apotek Desa Blahkiuh Niputuekanoviyanti; Trimayasa, Gede; saka, iwan
Journal Pharmactive Vol. 4 No. 1 (2025): Jurnal Pharmactive April
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

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Abstract

Pelayanan kefarmasian di apotek telah mengalami pergeseran paradigma dari yang berorientasi pada obat (drug oriented) menjadi berorientasi pada pasien (patient oriented), yang dikenal sebagai pharmaceutical care. Penelitian ini bertujuan untuk mengetahui karakteristik pasien di Apotek Desa Blahkiuh serta tingkat kepuasan mereka terhadap penerapan standar pelayanan kefarmasian. Penelitian ini menggunakan pendekatan kuantitatif dengan desain observasional dan metode cross-sectional. Data dikumpulkan melalui survei terhadap 97 responden yang merupakan konsumen apotek, kemudian dianalisis menggunakan uji karakteristik dan uji bivariat untuk melihat hubungan antarvariabel. Hasil penelitian menunjukkan mayoritas responden berusia 17– 27 tahun (54,6%), berjenis kelamin perempuan (50,5%), berpendidikan SMA (62,9%), dan berprofesi sebagai ibu rumah tangga (30,9%). Sebagian besar responden (95,9%) telah berkunjung ke apotek lebih dari lima kali. Uji bivariat menunjukkan bahwa dimensi Reliability (p=0,001), Responsiveness (p=0,001), Assurance (p=0,001), dan Tangible (p=0,025) memiliki hubungan signifikan dengan tingkat kepuasan pasien. Sebaliknya, dimensi Empathy (p=0,261) tidak menunjukkan hubungan yang signifikan. Kesimpulannya, karakteristik responden didominasi oleh pasien berusia 17–27 tahun, perempuan, berpendidikan SMA, dan ibu rumah tangga dengan kunjungan yang tinggi. Sebagian besar dimensi pelayanan kefarmasian, yaitu Reliability, Responsiveness, Assurance, dan Tangible, memiliki hubungan signifikan terhadap kepuasan pasien di Apotek Desa Blahkiuh.
KAJIAN PERESEPAN RACIKAN STUDI RETROSPEKTIF PADA PASIEN PEDIATRI RSUD KABUPATEN TEGAL Nisa, Silviatun
Journal Pharmactive Vol. 4 No. 1 (2025): Jurnal Pharmactive April
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

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Abstract

The treatment of pediatric patients requires special attention because the organ systems of children are immature and continue to develop as they grow, concoction prescriptions are often found in pediatric patients, The demand for concoction prescriptions in pediatric patients arises from various specific needs of the patients such as administering a dose based on body weight, difficulty swallowing. Drug mixtures in concoction prescriptions increase the risk of drug incompatibility and interactions,Tthe research conducted was a cros sectional research with a retrospective approach. The data was 127 prescriptions concocted by outpatients in 2024, analyzed using Medscape stokley’s drug interactions, and literature study. The results showed that of 127 patients with male patients, 71 patients (55.9%) were female while the number of female patients was (44.1%). In the one-year period 52 cases (40.94) were found with dosage inaccuracies and stability problems in two cases (5.51%). From the analysis of 127 prescriptions, it was found that 66 prescriptions (52%) involved drug interactions with a moderate level of severity. The most common interactions occurred in combinations such as Catroptil + Furosemide + Lactosum, Tremenza + Salbutamol + Lactosum, and Phenytoin + Lactosum. Additionally, the potential for pharmaceutical problems was found to be an average of (46.46) Keywords: Drug interactions, pediatric, prescription concoctions.
PROFIL ADVERSE DRUG REACTION OBAT ANTIDIABETES PADA PASIEN PROLANIS DI PUSKESMAS PAGIYANTEN KECAMATAN ADIWERNA Auranisa, Wiwit Baitul
Journal Pharmactive Vol. 4 No. 1 (2025): Jurnal Pharmactive April
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

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Abstract

The use of antidiabetic drugs often results in side effects experienced by patients with type 2 diabetes mellitus, such as dizziness, nausea, tingling sensations, weakness, hypoglycemia, and gastrointestinal disturbances. These side effects commonly occur in patients undergoing long-term therapy. The relationship between drug side effects and drug use can be assessed using the Naranjo algorithm. At Puskesmas Pagiyanten, Prolanis patients are treated under a program implemented by the government in collaboration with BPJS Kesehatan. Indonesia ranks as the fifth country with the highest number of diabetes patients globally, with 19.5 million cases reported in 2021. Puskesmas Pagiyanten recorded 1,046 cases of diabetes mellitus in 2023, which increased to 1,098 cases in 2024. This study aimed to determine the prevalence, types, and probability scores of antidiabetic drug side effects in Prolanis patients with type 2 diabetes mellitus at Puskesmas Pagiyanten, Adiwerna Subdistrict. This research was an observational study with a cross-sectional design, involving 40 Prolanis patients as the sample using total sampling. Data sources included primary data obtained through direct interviews with Prolanis patients and secondary data from medical records. The results showed that the highest prevalence of side effects was found in Metformin users (63%), followed by the combination of Metformin and Glimepiride (38%). According to the Naranjo algorithm, 57.50% of the side effects were categorized as probable, indicating a high likelihood of being related to drug use. Thus, regular monitoring of drug side effects is necessary to improve the safety of long-term therapy in type 2 diabetes mellitus patients.
ANALISIS PENYIMPANAN VAKSIN DI PUSKESMAS KEDIRI I KABUPATEN TABANAN Listiani, Putu Ayu Ratih; Putu Ika Indah Indraswari; Ziyyan Silfia Haani
Journal Pharmactive Vol. 4 No. 1 (2025): Jurnal Pharmactive April
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

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Abstract

Vaccines are biological products that stimulate the body's immunity and are very susceptible to damage, so they require special handling to maintain their quality. One of them is that proper storage of vaccines is very important because this can have an impact on its potency. This study aims to evaluate the effectiveness of vaccine storage at the Kediri 1 Tabanan Community Health Center using three main indicators: facilities and infrastructure, condition of the refrigerator, and vaccine storage system. Descriptive observational research with a semi-quantitative study design is the methodology employed. The analysis's findings indicate that the facilities and infrastructure indicators scored 81.81%, placing them in the good category. With a percentage of 87.5%, the refrigerator condition indicator is also in the good range. Aside from that, the indicators of the vaccine storage system performed well, with an 85.71% percentage. In summary, the Kediri 1 Tabanan Community Health Center's overall vaccination storage falls within the "good" category. Despite the fact that there is still room for advancement to achieve complete vaccine storage optimization
FORMULASI SABUN PADAT EKSTRAK BEKATUL BERAS MERAH (Oryza nivara) DENGAN METODE COLD PROCESS SEBAGAI ANTIBAKTERI TERHADAP Staphylococcus aureus Ni Luh Gde Mona Monika; Yunita, Ella; Ratih Listiani, Putu Ayu
Journal Pharmactive Vol. 4 No. 1 (2025): Jurnal Pharmactive April
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

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Abstract

Red Rice Bran (Oryza nivara) is one of the natural ingredients that contains flavonoids, tannins, alkaloids, and terpenoids that are able to provide antibacterial activity. The purpose of this study is to determine the antibacterial activity of solid soap preparations of 96% ethanol extract of brown rice bran by cold process method against Staphylococcus aureus bacteria. The extraction process is carried out by the maceration extraction method, namely by using 96% ethanol solvent. The antibacterial activity test of the extract was carried out using Staphylococcus aureus test bacteria with variations in the concentration of ethanol extract of brown rice bran which were 1.5%, 2.5%, and 3.5%. The antibacterial activity test of solid soap of brown rice bran extract was carried out using Staphylococcus aureus test bacteria with F0, F1, F2 and F3 formulations. The method used for the antibacterial activity test was diffusion with Kirby-baurer disc paper discs using Mueller Hilton agar media. The results of the antibacterial activity test of solid soap preparations of 96% ethanol extract of brown rice bran by cold process method have antibacterial activity with moderate inhibitory power against Staphylococcus aureus bacteria. The inhibition comes from the soap base, the addition of extracts to the 2%, 2.5%, 3% concentration variations does not provide an increase in inhibition against the growth of Staphylococcus aureus bacteria.
TINJAUAN DIGITAL MARKETING TERHADAP MINAT BELI DAN KEPUTUSAN PEMBELIAN PRODUK KOSMETIK Gusti Ayu Oviani; Murti, Ida Bagus Teguh Teja; Yogatama, I Made Wahyu
Journal Pharmactive Vol. 4 No. 1 (2025): Jurnal Pharmactive April
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

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Abstract

The implementation of digital marketing makes it easier for potential consumers to obtain product information and conduct online transactions for various products, including cosmetics. Several studies have investigated the relationship between digital marketing and purchasing interest and decisions for cosmetic products, yielding positive results. By understanding how digital marketing influences purchasing interest and purchasing decisions comprehensively, businesses can design more effective and consumer-oriented marketing strategies. The method used in this review is a literature study by searching for articles from primary data sources over the past five years using related keywords. Articles included in this review were those that met the inclusion and exclusion criteria. The results of the study of 14 articles are presented in a table based on the author's name, year, title, objectives, methods, and findings. The relationship between digital marketing and purchasing interest and purchasing decisions for cosmetic products indicates that digital marketing has a positive and significant contribution in influencing consumers. Efforts are needed to improve digital literacy for both businesses and the public to optimally adapt to digital marketing platforms.

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