Jurnal Pharmactive
Initially LPPM Institut Teknologi dan Kesehatan Bintang Persada published a journal that aimed to accommodate campus internal lecturers at Institut Teknologi dan Kesehatan Bintang Persada in publishing scientific papers. Because the lecturers who want to carry out publications come from various fields of science, such as Clinical andCommunity Pharmacy, Pharmaceutical Analysis, Herbal Medicine, Pharmaceutical Techology, Management of Pharmacy, etc. the published journal seems not to have a clear focus area (accepting all types of articles). In addition, efforts to improve journal management by LPPM, as well as accreditation demands for scientific periodicals / journals determined by related parties. FOCUS AND SCOPE Clinical and Community Pharmacy Pharmaceutical Analysis Herbal Medicine Pharmaceutical Technology Management of Pharmacy
Articles
48 Documents
<![CDATA[PENGARUH METODE PENGOLAHAN TERHADAP PENETAPAN KADAR AKRILAMIDA PADA POPCORN SECARA KROMATOGRAFI CAIR KINERJA TINGGI ]]>
<![CDATA[Iswandi, Iswandi]]>;
<![CDATA[Roshinta Wulandari, Sasongko]]>;
<![CDATA[Anita Nilawati]]>
<![CDATA[ Journal Pharmactive Vol. 2 No. 2 (2023): Jurnal Pharmactive Oktober ]]>
Publisher : <![CDATA[Institut Teknologi dan Kesehatan Bintang Persada ]]>
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DOI: 10.64036/pharmactive.v2i2.33
<![CDATA[Acrylamide is a compound that is known to cause cancer and is potentially carcinogenic in humans. Acrylamide is formed in foods that contain carbohydrates and proteins when exposed to high temperature. One popular food that has the potential to generate acrylamide is popcorn. This research aims to determine the levels of acrylamide in popcorn using different processing methods, namely frying and baking, through High Performance Liquid Chromatography. Popcorn samples were obtained from the frying and oven method at 1560C. Sample preparation was carried out by extraction technique using dichlormethane and ethanol solvents. Acrylamide analysis was performed using High Performance Liquid Chromatography method with column C18, UV – Vis detector, wavelength 210 nm, mobile phase of 85% phosphoric acid in acetonitrile : aquabidest (5 : 95) and flow rate of 0.5 mL/min. Acrylamide testing begins with method validation including linearity, LOD, LOQ, accuracy and precision along with the determination of acrylamide levels. Data analysis using SPSS with the Shapiro – Wilk method and Independent Sample t – test. Based on the research, it was found that the results of method validation on the linearity coefficient were 0.999, the LOD test obtained 0.3933 ppm and LOQ 1.1918 ppm. The accuracy test obtains a recovery value of 97.29% and a precision value of 1.36%. Acrylamide levels for fried popcorn samples obtained an average level of 0,0417 g/kg. Acrylamide levels for oven popcorn samples obtained an average level of 0,0501 g/kg. The results of this study showed that there was no significant difference between fried popcorn and oven popcorn as evidenced by the SPSS test with a sig value of > 0.05.]]>
<![CDATA[UJI TOKSISITAS EKSTRAK ETANOL 96% DAUN MIANA (Plectranthus scutellaroides R.Br) TERHADAP Artemia salina DENGAN METODE BSLT (Brine Shrimp Lethality Test) ]]>
<![CDATA[Puspita Sari, Dyah Ratna Ayu]]>;
<![CDATA[Putu Yudha Ugrasena]]>;
<![CDATA[Ni Putu Ayu Desi Astini]]>;
<![CDATA[I Gede Agus Sindhu A]]>
<![CDATA[ Journal Pharmactive Vol. 2 No. 2 (2023): Jurnal Pharmactive Oktober ]]>
Publisher : <![CDATA[Institut Teknologi dan Kesehatan Bintang Persada ]]>
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DOI: 10.64036/pharmactive.v2i2.34
<![CDATA[Medicinal plants are one of the efforts used to control disease. The benefits of medicinal plants have been passed down from generation to generation by our ancestors. One plant that has medicinal properties is miana leaves (Plectranthus scutellaroides R.Br). In this research, the extraction method used was maceration, with 96% ethanol solvent. Miana leaf ethanol extract was screened for phytochemicals and toxicity tested using the Brine Shrimp Lethality Test (BSLT) method. Toxicity tests were carried out at various concentrations of 100 ppm, 250 ppm, 500 ppm, 750 ppm and 1000 ppm. The results of phytochemical screening on miana leaves show that miana leaves contain flavonoid compounds, tannins, saponins, steroids, but do not contain alkaloids and triterpenoids. The 96% ethanol extract of miana leaves (Plectranthus scutellaroides R.Br) has an LC50 value of 511.58 ppm, included in the toxic category with an LC50 value in the range of 30-1000 ppm.]]>
<![CDATA[GAMBARAN PENYIMPANAN SEDIAAN OBAT DI APOTEK X KUTA UTARA KABUPATEN BADUNG ]]>
<![CDATA[Oviani, Gusti Ayu Oviani]]>
<![CDATA[ Journal Pharmactive Vol. 2 No. 2 (2023): Jurnal Pharmactive Oktober ]]>
Publisher : <![CDATA[Institut Teknologi dan Kesehatan Bintang Persada ]]>
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DOI: 10.64036/pharmactive.v2i2.35
<![CDATA[A Pharmacy is a pharmaceutical service facility where practice pharmacy was done by a pharmacist. The drug storage system must comply with pharmaceutical service standards because inappropriate drug storage can affect the quality of the drug. The purpose of this study was to determine the description of the storage of drug preparations at the Kuta Utara X pharmacy. This study uses a quantitative observation design. This study uses samples of all ethical and self service pharmaceutical drugs for indicators of the percentage of expired and damaged drugs, percentage of dead stock drugs, and drug void time. Drug suitability with stock cards using 100 drug samples. The data taken is then analyzed using indicators. The results showed that the suitability of drugs with card stock, namely 86% did not meet the standards (100%); Expired drug that is 0.04% already meets the standard (?0.2%), and the Percentage of dead stock of 1.22% has not met the standard (0%), and the average drug vacancy time is 2 days, it does not meet the standard (0 days).]]>
<![CDATA[GAMBARAN TINGKAT KEPUASAN PASIEN TERHADAP PELAYANAN KEFARMASIAN PADA PASIEN RAWAT JALAN DI UPTD PUSKESMAS MENGWI 1 TAHUN 2021 ]]>
<![CDATA[Ika Indah Indraswari, Putu]]>;
<![CDATA[Kalpika, Putu Eka]]>
<![CDATA[ Journal Pharmactive Vol. 2 No. 2 (2023): Jurnal Pharmactive Oktober ]]>
Publisher : <![CDATA[Institut Teknologi dan Kesehatan Bintang Persada ]]>
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DOI: 10.64036/pharmactive.v2i2.37
<![CDATA[Abstract This study used is an observational method with cross-sectional approach. The sample was collected using purposive sampling technique and using a questionnaire that has been tested for validity and reliability. Research data are presented in the form of percentages and diagrams to describe the distribution and frequency of respondents' characteristics, where research results are presented in tabular form. The results of the questionnaire research were sought whether there was a gap between patient perceptions and expectations of pharmaceutical services at the UPTD Puskesmas Mengwi 1 based on technique ServQual Model. Based on the results of the research that has been carried out, it can be concluded that the level of patient perception and expectation of pharmaceutical services at UPTS Puskesmas Mengwi 1 is the average perception of the patient (respondents) which is 3.40 with a high classification and the average expectation of patients (respondents) is 3, 45 with a very high classification. Based on thetechnique ServQual modelused, there is a gap between the perception and expectation of the patient (respondent) of -0.05 for pharmaceutical services at the UPTD Puskesmas Mengwi 1. Keywords: Outpatient, Satisfaction, Pharmaceutical Service, Public Health Center Abstrak Penelitian yang digunakan menggunakan metode observasional dengan pendekatan cross-sectional. Pengambilan sampel dilakukan dengan teknik purposive sampling dan menggunakan kuesioner yang telah teruji validitas dan reliabilitasnya. Data penelitian disajikan dalam bentuk persentase dan diagram untuk menggambarkan sebaran dan frekuensi karakteristik responden, dimana hasil penelitian disajikan dalam bentuk tabel. Hasil penelitian kuesioner dicari apakah terdapat kesenjangan antara persepsi dan harapan pasien terhadap pelayanan kefarmasian di UPTD Puskesmas Mengwi 1 berdasarkan teknik ServQual Model. Berdasarkan hasil penelitian yang telah dilakukan dapat disimpulkan bahwa tingkat persepsi dan harapan pasien terhadap pelayanan kefarmasian di UPTS Puskesmas Mengwi 1 rata-rata persepsi pasien (responden) yaitu sebesar 3,40 dengan klasifikasi tinggi. dan rata-rata ekspektasi pasien (responden) sebesar 3,45 dengan klasifikasi sangat tinggi. Berdasarkan teknik model ServQual yang digunakan, terdapat gap antara persepsi dan harapan pasien (responden) sebesar -0,05 terhadap pelayanan kefarmasian di UPTD Puskesmas Mengwi 1.]]>
<![CDATA[FORMULASI DAN UJI MUTU FISIK SABUN TRANSPARAN EKSTRAK ETANOL BONGGOL NANAS (Ananas comosus L.) ]]>
<![CDATA[Listiani, Putu Ayu Ratih]]>
<![CDATA[ Journal Pharmactive Vol. 2 No. 2 (2023): Jurnal Pharmactive Oktober ]]>
Publisher : <![CDATA[Institut Teknologi dan Kesehatan Bintang Persada ]]>
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DOI: 10.64036/pharmactive.v2i2.40
<![CDATA[Bonggol nanas selama ini masih sering dibuang dan dianggap limbah, padahal apabila dijadikan zat aktif dalam sediaan sabun mandi dapat berfungsi untuk melembabkan dan melembutkan kulit. Berdasarkan skrining fitokimia menunjukkan bahwa nanas memiliki kandungan fenolat, flavonoid, tannin, alkaloid dan saponin yang berfungsi sebagai antioksidan yang dapat menangkal efek negatif radikal bebas terhadap kulit. Ekstraksi bonggol nanas dilakukan dengan metode maserasi menggunakan pelarut etanol 96% dan diuapkan menggunakan rotary evaporator sehingga didapatkan ekstrak kental yang berwarna hitam. Ekstrak yang didapatkan kemudian diformulasikan menjadi sediaan sabun transparan. Pengujian mutu fisik sediaan dilakukan untuk memastikan bahwa sediaan yang dibuat telah memuhi persyaratan. Hasil uji mutu fisik meliputi uji organoleptis, tinggi busa, uji pH, hoogenitas dan uji transparansi sabun menunjukkan bahwa sediaan sabun yang dihasilkan telah memenuhi persyaratan dan layak untuk digunakan.. Kata Kunci: Bonggol nanas, sabun transparan, ekstraksi, mutu fisik]]>
<![CDATA[GAMBARAN PENGGUNAAN PPI DAN H2RA PADA PASIEN DISPEPSIA DI INSTALASI GAWAT DARURAT RUMAH SAKIT UMUM NEGARA ]]>
<![CDATA[I Gede Bagus Indra, Marangyana]]>;
<![CDATA[Ella, Yunita]]>
<![CDATA[ Journal Pharmactive Vol. 2 No. 2 (2023): Jurnal Pharmactive Oktober ]]>
Publisher : <![CDATA[Institut Teknologi dan Kesehatan Bintang Persada ]]>
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DOI: 10.64036/pharmactive.v2i2.41
<![CDATA[Dyspepsia is a syndrome consisting of pain or discomfort in the pit of the stomach, bloating, nausea, vomiting, belching, feeling full quickly, and feeling full. This disease is one type of disease with a high prevalence in Indonesia and in the world. This study aims to determine the profile and description of the use of PPI and H2RA in dyspeptic patients at the Emergency Unit in Negara General Hospital on January - December 2021. This study was a non-experimental descriptive study with retrospective data collection method. The results of the study showed that the most patients were female by 56% (132 people), age group > 55 years by 27.35% (64 people), private employee occupation by 39.32% (92 people) and the last education was Senior High School by 38.46% (90 people). The most frequently prescribed drugs for dyspeptic patients were oral PPI + H2RA injection by 32.05% (75 people).]]>
<![CDATA[EVALUASI PENYIMPANAN DAN DISTRIBUSI OBAT NARKOTIKA DAN PSIKOTROPIKA DI APOTEK OKE FARMA ]]>
<![CDATA[Trima Yasa, Gede]]>;
<![CDATA[Dwike Swari Santi, Ni Made]]>;
<![CDATA[Deviana Gayatri, Ni Putu Ayu]]>
<![CDATA[ Journal Pharmactive Vol. 2 No. 2 (2023): Jurnal Pharmactive Oktober ]]>
Publisher : <![CDATA[Institut Teknologi dan Kesehatan Bintang Persada ]]>
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DOI: 10.64036/pharmactive.v2i2.42
<![CDATA[Pengelolaan obat yang baik merupakan faktor utama dalam mendukung tingkat kesembuhan penyakit pasien, oleh karena itu pengelolaan obat yang baik harus terlaksana di apotek. Pengelolaan obat yang baik terlebih yaitu pengelolaan jenis obat yang bersifat psikoaktif seperti obat-obatan narkotika dan psikotropika. Kegiatan penyimpanan dan distribusi obat yang kurang baik merupakan masalah yang dapat mengganggu dalam upaya peningkatan mutu obat di apotek. Permasalahan yang sering ditemukan pada sistem penyimpanan dan distribusi diantaranya yaitu tidak menggunakan sistem first in first out (FIFO) atau first expired first out (FEFO), sistem alfabetis, kartu stok, tidak menempatkan obat pada tempat yang semestinya. Apotek adalah sarana atau tempat dilakukan praktek kefarmasian oleh farmasi yang meliputi penyimpanan, pengadaan, serta penyerahan obat kepada pasien dan memberikan penjelasan tentang cara penggunaan obat atau biasa disebut pemberian informasi obat. Tujuan dari penelitian ini adalah Untuk mengetahui evaluasi penyimpanan dan distribusi obat narkotika dan psikotropika di Apotek Oke Farma. Penelitian ini menggunakan medote deskriptif dengan pengambilan data secara crossectional yaitu menggambarkan pengadaan, penerimaan, penyimpanan, pendistribusian, pencatatan, dan pelaporan, serta pemusnahan obat golongan narkotika dan psikotropika di Apotek Oke Farma. Berdasarkan hasil peneitian kesesuain pelaksanaan distribusi dan penyimpanan obat narkotika dan psikotropia di Apotek Oke Farma dengan permenkes no 13 tahun 2015 yaitu pada penyimpanan dinyatakan baik dengan persentase 100% dan pada pendistribusian dinyatakan baik dengan persentase 90%.]]>
<![CDATA[Evaluasi Penggunaan Antibiotik pada Pasien Demam Tifoid Rawat Inap di Rumah Sakit X Denpasar Secara Kuantitatif Menggunakan Metode ATC/DDD ]]>
<![CDATA[Artika, Made Prita]]>
<![CDATA[ Journal Pharmactive Vol. 2 No. 2 (2023): Jurnal Pharmactive Oktober ]]>
Publisher : <![CDATA[Institut Teknologi dan Kesehatan Bintang Persada ]]>
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DOI: 10.64036/pharmactive.v2i2.44
<![CDATA[Demam tifoid adalah penyakit endemis yang disebabkan oleh Salmonella typhi yang menginfeksi saluran pencernaan sehingga mengakibatkan peradangan pada bagian usus halus dan lumen usus. Tahun 2018 jumlah kasus penyakit demam tifoid di seluruh dunia diperkirakan sekitar 20 - 21 juta kasus dengan insidensi 128.000 sampai 161.000 kasus kematian setiap tahunnya. Penelitian ini bertujuan untuk mengetahui profil dan Kuantitas penggunaan antibiotik pada pasien demam tifoid di Instalasi Rawat Inap Rumah Sakit “X” Denpasar. Metode yang digunakan pada penelitian ini adalah observasional dengan pengambilan data secara retrospektif yaitu mengambil data rekam medis periode Januari– Juni tahun 2022. Penelitian ini menggunakan sampel 52 pasien usia 18-55 tahun. Hasil penelitian menunjukan pasien demam tifoid paling banyak terjadi pada pasien jenis kelamin perempuan sebesar 29 (55.77%). Profil penggunaan antibiotik pasien demam tifoid terbanyak yaitu antibiotik cefixime 18 (34.6%) dan kuantitas penggunaan antibiotic berdasarkan metode ATC/DDD melebihi Standar WHO yaitu antibiotic Levofloxacin sebesar 40,75 DDD/100 patient days.]]>
<![CDATA[Antibacterial Activity of 96% Ethanol Extract from Red Rice Bran (Oryza nivara) Against Escherichia coli: Uji Aktivitas Antibakteri Ekstrak Etanol 96% Bekatul Beras Merah (Oryza nivara) terhadap Escherichia coli ]]>
<![CDATA[Ni Luh Gde Mona Monika]]>;
<![CDATA[Ni Wayan Rika Kumara Dewi]]>;
<![CDATA[Ni Putu Gita Puspita Sari]]>
<![CDATA[ Journal Pharmactive Vol. 2 No. 2 (2023): Jurnal Pharmactive Oktober ]]>
Publisher : <![CDATA[Institut Teknologi dan Kesehatan Bintang Persada ]]>
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DOI: 10.64036/pharmactive.v2i2.45
<![CDATA[Red rice bran is a by-product produced from rice milling in Jatiluwih village, Tabanan, Bali which has secondary metabolites that have the potential to inhibit bacterial activity. The purpose of this study was to determine the potential of 96% ethanol extract of red rice bran to inhibit bacterial growth Escherichia coli. The research method started with the extraction process by maceration method using 96% ethanol solvent. The viscous extract obtained was then subjected to phytochemical screening which showed the presence of compounds flavonoid, alkaloid, and tannin. Antibacterial activity test using disc diffusion method paper disk, measured by looking at the clear zone formed and analyzed using the mean test. The antibacterial activity test results of red rice bran extract at concentrations of 20% (8.63 mm) and 25% (9.93 mm) were categorized as moderate, concentration 30% (10.33 mm) was categorized as strong inhibition. Positive control in this study using chloramphenicol 250 mg which resulted in an inhibition zone of 21.42 mm in the strong inhibition zone category. Comparison of the antibacterial activity of the 96% ethanol extract of red rice bran showed significant difference with p value <0.05.]]>
<![CDATA[ANALISIS TINGKAT KEPUASAN KONSUMEN TERHADAP KUALITAS PELAYANAN OBAT TANPA RESEP DI APOTEK CAHAYA FARMA ]]>
<![CDATA[Listiani, Putu Ayu Ratih]]>;
<![CDATA[Gusti Ayu Oviani]]>
<![CDATA[ Journal Pharmactive Vol. 3 No. 1 (2024): Jurnal Pharmactive April ]]>
Publisher : <![CDATA[Institut Teknologi dan Kesehatan Bintang Persada ]]>
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DOI: 10.64036/pharmactive.v3i1.46
<![CDATA[Apotek merupakan sarana pelayanan kefarmasian tempat dilakukan praktik kefarmasian dan penyaluran perbekalan obat kepada masyarakat. Kepuasan konsumen dapat mempengaruhi minat untuk kembali ke apotek yang sama. Penelitian ini dilakukan untuk menganalisis tingkat kepuasan konsumen terhadap kualitas pelayanan obat tanpa resep diapotek. Penelitian ini dilakukan di Apotek Cahaya Farma dengan jumlah sampel 60 orang pengambilan sampel dilakukan dengan metode accidental sampling. Instrumen penelitian yang digunakan berupa kuesioner tingkat kepuasan konsumen terhadap kualitas pelayanan kefarmasian. Hasil penelitian dari seluruh dimensi konsumen sangat puas teradap kualitas pelayanan obat tanpa resep di Apotek Cahaya Farma dengan nilai kualitas pelayanan pada dimensi kehandalan sebesar 4,2, pada dimensi daya tanggap sebesar 4,57, pada dimensi jaminan sebesar 4,48, pada dimensi empati sebesar 4,53, dan pada dimensi bukti fisik sebesar 4,54. Sehingga diperoleh nilai rata-rata dari 5 dimensi adalah 90,5 yang masuk dalam katagori sangat puas]]>
