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Jurnal Pharmactive
Published by Institut Teknologi dan Kesehatan Bintang Persada
ISSN : -     EISSN : 28293444     DOI : -
Core Subject : Education, Social,
Environmental Science Other
Initially LPPM Institut Teknologi dan Kesehatan Bintang Persada published a journal that aimed to accommodate campus internal lecturers at Institut Teknologi dan Kesehatan Bintang Persada in publishing scientific papers. Because the lecturers who want to carry out publications come from various fields of science, such as Clinical andCommunity Pharmacy, Pharmaceutical Analysis, Herbal Medicine, Pharmaceutical Techology, Management of Pharmacy, etc. the published journal seems not to have a clear focus area (accepting all types of articles). In addition, efforts to improve journal management by LPPM, as well as accreditation demands for scientific periodicals / journals determined by related parties. FOCUS AND SCOPE Clinical and Community Pharmacy Pharmaceutical Analysis Herbal Medicine Pharmaceutical Technology Management of Pharmacy
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 67 Documents
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the PENGARUH KUALITAS PELAYANAN KEFARMASIAN TERHADAP KEPUASAN KONSUMEN PADA APOTEK STAR MEDIKA 1 DAN STAR MEDIKA 2: PENGARUH KUALITAS PELAYANAN KEFARMASIAN TERHADAP KEPUASAN KONSUMEN PADA APOTEK STAR MEDIKA 1 DAN STAR MEDIKA 2 Ni Kadek Putri Satya Jayanti
Journal Pharmactive Vol. 4 No. 2 (2025): Jurnal Pharmactive Oktober
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64036/pharmactive.v4i2.70

Abstract

Consumer satisfaction is an important indicator in assessing the quality of pharmaceutical services in pharmacies, where the appearance of the pharmacy, friendliness of the staff, drug information services, drug availability, and speed of service are the main factors that influence it. The purpose of this study was to determine the effect of pharmaceutical service quality on consumer satisfaction at Star Medika 1 Pharmacy and Star Medika 2 Pharmacy and to identify the most dominant service elements that influence consumer satisfaction. This study used a quantitative method with a descriptive approach and cross-sectional design, involving 120 consumers selected using purposive sampling techniques, where data were collected through questionnaires that had been tested for validity and reliability, then analyzed with the Spearman correlation test using the SPSS 24 application. The results of the study showed that all indicators of service quality had a positive effect on consumer satisfaction. The dimensions of drug availability with a correlation coefficient of r = 0.765 with a significance of 0.000, friendliness of officers with a correlation coefficient of r = 0.757 with a significance of 0.000, drug information service correlation of r = 0.733 with a significance of 0.000, speed of service with a correlation coefficient of r = 0.732 with a significance of 0.000. These four dimensions have the strongest correlation to consumer satisfaction. The results of the study at Star Medika Pharmacy 1 and concluded that the characteristics of respondents were dominated by women aged 31-40 years with private/self-employed jobs who tended to return to shop 2-5 times. All aspects of pharmacy services, especially drug availability, friendliness of officers, drug information service, and speed of service, have a very strong relationship (correlation of 0.7302) and have a positive effect on consumer satisfaction.
HUBUNGAN DATA DEMOGRAFI TERHADAP PENGETAHUAN TENTANG ANTIBIOTIK hasan2002
Journal Pharmactive Vol. 4 No. 2 (2025): Jurnal Pharmactive Oktober
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64036/pharmactive.v4i2.72

Abstract

The irrational use of antibiotics is the main cause of increasing bacterial resistance in the community. Demographic data is thought to influence antibiotic use behavior. This study aims to determine the relationship between demographic data and knowledge about antibiotics in the community. This is a quantitative study with a cross-sectional design. A sample of 218 respondents was selected using convenience sampling and snowball sampling techniques. Data were collected through a questionnaire measuring the level of knowledge about antibiotics and demographic data of the respondents. Data analysis was performed using univariate and bivariate analysis with the Spearman Rank test. Demographic factors such as educational level were significantly associated with knowledge levels and behavior (p < 0.05). Knowledge levels significantly influenced antibiotic usage behavior. Demographic characteristics also play a role in shaping rational antibiotic usage behavior in the community.
PENGARUH PELAYANAN KEFARMASIAN TERHADAP KEPUASAN PASIEN RAWAT JALAN PESERTA BPJS KESEHATAN DI INSTALASI FARMASI PUSKESMAS SAWAN 2 Made Dwike Swari Santi
Journal Pharmactive Vol. 4 No. 2 (2025): Jurnal Pharmactive Oktober
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64036/pharmactive.v4i2.75

Abstract

Pharmaceutical services are an essential part of the healthcare system in public health centers (puskesmas), particularly in supporting the success of patient treatment. The Pharmacy Installation at Puskesmas Sawan 2 serves an average of 80–90 outpatients per day, most of whom are BPJS Health participants. However, there are still patient complaints regarding the waiting time for medication services. This study aims to determine the effect of pharmaceutical services on the satisfaction of outpatient BPJS Health participants at the Pharmacy Installation of Puskesmas Sawan 2. This research employed a quantitative method with a cross-sectional design. The sample consisted of 112 respondents selected using purposive sampling. Data were collected through a questionnaire and analyzed using the Spearman correlation test. The results showed a significant but weak correlation in the tangible dimension (p<0.001) and responsiveness (p=0.019), a significant moderate correlation in the assurance (p<0.001) and empathy (p<0.001) dimensions, while the reliability dimension showed no significant correlation (p=0.060). Improving service quality, particularly in terms of responsiveness, is necessary
EVALUASI PENGGUNAAN ANTIBIOTIK PADA PASIEN PEDIATRI RAWAT INAP DI RUMAH SAKIT UMUM GANESHA Ni Kadek Putri Dwiyanti
Journal Pharmactive Vol. 4 No. 2 (2025): Jurnal Pharmactive Oktober
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64036/pharmactive.v4i2.76

Abstract

The use of antibiotics in pediatric patients is often inappropriate and risks causing resistance, prolonging the hospitalization, and effectiveness decreasing. Pediatrics are a group that requires more attention in antibiotic therapy due to the differences in pharmacokinetics and pharmacodynamics compared to adults. This study aims to evaluate the pattern, quality, and quantity of antibiotic use in pediatric patients at Ganesha General Hospital for the period October–December 2024, and relationship between the quality of antibiotic use and the length of hospitalization. The research design is descriptive-analytic retrospective with a quantitative approach. The evaluation of the quality of antibiotic use using Gyssens method, while the quantity using ATC/DDD and DU90% methods. The data were analyzed univariate and bivariate using Chi-Square test. The results on 97 patients showed that cephriaxone was the most used antibiotic (80.8%) with DDD/100 patient value of 51.28. The quality showed 83.51% of antibiotic use was rational (category 0), 16.49% were in category VI (incomplete data) of 7.22%. The results of Chi-Square test showed there was no significant relationship between the quality of antibiotic use and the length of hospitalization (p = 0.410). The conclusion is that there is still a high level of irrational use of antibiotics.
; Evaluasi Penggunaan Antibiotik Pada Pasien Rawat Inap Dengan Pneumonia Di Rumah Sakit Umum Ganesha rinandapriandini18
Journal Pharmactive Vol. 4 No. 2 (2025): Jurnal Pharmactive Oktober
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64036/pharmactive.v4i2.77

Abstract

According to the 2018 Basic Health Research (Riset Kesehatan Dasar), theprevalence of pneumonia in Indonesia increased from 2013 by 0.4%, reaching2.0% in 2018. This indicates that pneumonia remains a significant public healthconcern. This study employed a descriptive-analytic design using a retrospectiveapproach with secondary data to evaluate the quality and quantity of antibiotic usein pneumonia patients. The qualitative aspect of antibiotic use was assessed usingthe Gyssens method, while the quantitative evaluation was conducted using theATC/DDD method. Levofloxacin was found to be the most commonly usedantibiotic, both in parenteral form (34.05 DDD/100) and oral form, indicating itsdominant role as a primary treatment option. According to the 2023 NationalClinical Practice Guidelines (PNPK), 90.26% of antibiotic use was classified asrational (Category 0) based on the Gyssens evaluation, while 9.73% fell intoCategory IVa (there was a more effective alternative available).Chi-Squareanalysis showed a p-value of 0.652 (p > 0.05), indicating that there was nostatistically significant association between the quality of antibiotic use (rationalvs. irrational) and the length of hospital stay (?3 days vs. >3 days).Although thestatistical analysis did not yield a significant result, irrational use of antibiotics stillposes risks such as reduced treatment effectiveness, increased antimicrobialresistance, prolonged hospitalization, higher treatment costs, and potential clinicalcomplications. Therefore, rational antibiotic use remains essential to supporttreatment success and prevent adverse long-term outcomes.
Tinjauan Terapi Empiris Meningitis Nosokomial oleh Enterobacteriaceae Resisten Multidrug Meli, Ayu; putri, melista
Journal Pharmactive Vol. 4 No. 2 (2025): Jurnal Pharmactive Oktober
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64036/pharmactive.v4i2.81

Abstract

Nosocomial meningitis is a hospital-acquired infection of the meninges, frequently occurring after neurosurgical interventions and associated with high mortality. Multidrug-resistant Enterobacteriaceae (MDRE) are a major cause of this infection, presenting challenges in selecting effective empirical antibiotic therapy. This review examines the clinical features, pathogen distribution, and empirical treatment strategies in nosocomial meningitis caused by MDRE, based on a cohort study from two neurosurgical centers in Northern China. Klebsiella pneumoniae was identified as the dominant pathogen, with blaKPC as the most prevalent resistance gene. Mortality risk increased in patients with external ventricular drainage and low Glasgow Coma Scale scores. Most patients received a combination of prophylactic, empirical, and definitive antibiotic therapies. These findings underscore the importance of risk-based treatment strategies and molecular diagnostics to optimize empirical therapy, reduce mortality, and combat antimicrobial resistance in nosocomial meningitis. Keywords: meningitis nosocomial, MDRE, Klebsiella pneumoniae
RESISTENSI ANTIBIOTIK DAN STRATEGI FARMAKOLOGIS TERBARU: INTEGRASI BUKTI GLOBAL DAN LOKAL dewi mega, dewi
Journal Pharmactive Vol. 5 No. 1 (2026): Jurnal Pharmactive April
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64036/pharmactive.v5i1.82

Abstract

Antimicrobial resistance (AMR) continues to be a global threat, especially in nosocomial infections that are increasingly difficult to treat. This study summarizes findings from ten international and national journals discussing various aspects of antibiotic resistance from 2020 to 2025, covering the prevalence of multidrug-resistant pathogens, the rationality of antibiotic use, and future therapeutic innovations. In China, resistance in hospital-acquired infections shows an increasing trend, particularly in Pseudomonas aeruginosa and Acinetobacter baumannii. Corynebacterium striatum has also been reported as an emerging invasive pathogen with a global increase in cases since 1976. In Indonesia, local studies have noted the high prevalence of multidrug-resistant Klebsiella pneumoniae and the misuse of empirical antibiotics not based on pharmacokinetics. Additionally, the use of nebulized antibiotics shows potential for preventing Gram-negative infections in critically ill patients. Innovative therapeutic approaches, including new-generation antibiotics based on biotechnology such as CRISPR and phage therapy, show potential in combating resistance. Resistance control programs, such as routine antibiogram evaluation and healthcare worker education, are key to mitigation efforts. This review emphasizes the need for integration between clinical, microbiological, and pharmacological policy approaches to sustainably control antibiotic resistance. By combining global and national data, this article provides a comprehensive overview of the current landscape of antibiotic resistance and the prospects for more specific, adaptive, and rational therapies in the future.
Tinjauan Sistematis Penggunaan Antibiotik Reserve pada Infeksi Nosokomial: Efektivitas, Keamanan, dan Tantangan Implementasi : Efektivitas, Keamanan, dan Tantangan Implementasi yesi
Journal Pharmactive Vol. 5 No. 1 (2026): Jurnal Pharmactive April
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64036/pharmactive.v5i1.83

Abstract

Nosocomial pneumonia, including ventilator-associated pneumonia (VAP), is one of the most common infections in hospitals and carries high morbidity and mortality rates. The increasing prevalence of multiresistant (MDR) pathogens has complicated the treatment of these infections and demands more innovative and evidence-based therapeutic approaches. This literature review aims to summarize the latest findings from ten recent studies related to treatment strategies for nosocomial pneumonia and VAP, particularly regarding the identification of MDR pathogens, the development of new therapeutic molecules, and the treatment approaches implemented. The review results indicate that prompt and appropriate empiric therapy, the use of biomarkers to guide therapy, and the application of newer-generation antibiotics play a crucial role in infection control. Furthermore, the implementation of prevention programs and microbiological surveillance are key to minimizing the spread of antimicrobial resistance. In conclusion, the treatment of nosocomial pneumonia and VAP must be carried out in an integrated, multidisciplinary approach that includes early detection, therapy tailored to local resistance patterns, and strengthening hospital prevention policies.
Tinjauan Pendekatan Terbaru dalam Pengobatan Pneumonia Nosokomial dan Ventilator-Associated Pneumonia (VAP): Pendahuluan, Metode Penelitian, Hasil dan Pembahasan, Kesimpulan (Diikuti dengan Daftar Pustaka) Prasanti, Amanda
Journal Pharmactive Vol. 5 No. 1 (2026): Jurnal Pharmactive April
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64036/pharmactive.v5i1.88

Abstract

Nosocomial pneumonia, including ventilator-associated pneumonia (VAP), is one of the most common infections in hospitals and carries high morbidity and mortality rates. The increasing prevalence of multiresistant (MDR) pathogens has complicated the treatment of these infections and demands more innovative and evidence-based therapeutic approaches. This literature review aims to summarize the latest findings from ten recent studies related to treatment strategies for nosocomial pneumonia and VAP, particularly regarding the identification of MDR pathogens, the development of new therapeutic molecules, and the treatment approaches implemented. The review results indicate that prompt and appropriate empiric therapy, the use of biomarkers to guide therapy, and the application of newer-generation antibiotics play a crucial role in infection control. Furthermore, the implementation of prevention programs and microbiological surveillance are key to minimizing the spread of antimicrobial resistance. In conclusion, the treatment of nosocomial pneumonia and VAP must be carried out in an integrated, multidisciplinary approach that includes early detection, therapy tailored to local resistance patterns, and strengthening hospital prevention policies.
KESESUAIAN RESEP PASIEN UMUM RAWAT JALAN POLI ANAK DAN POLI OBGYN DENGAN FORMULARIUM RSU X Oviani, Gusti Ayu; Gayatri, Ni Putu Ayu Deviana; Yunita, Ella
Journal Pharmactive Vol. 4 No. 2 (2025): Jurnal Pharmactive Oktober
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The appropriate and guideline-based use of medications is an important factor in providing optimal pharmaceutical care to outpatient patients in the Pediatric and Obstetrics and Gynecology clinics at X General Hospital. Therefore, it is necessary to conduct research to evaluate the suitability of prescriptions. This study aims to evaluate the suitability of outpatient prescriptions in the Pediatric and Obstetrics and Gynecology clinics with the Formulary of X General Hospital (X General Hospital Formulary). The research method used in this study was prospective observational research. The collected data were analyzed descriptively. The study was conducted at X General Hospital in April 2023. The sample of this study consisted of 69 prescriptions from the Pediatric clinic and 50 prescriptions from the Obstetrics and Gynecology clinic, which were selected using purposive sampling technique and met the inclusion criteria while not meeting the exclusion criteria. The results of the analysis showed that 88% of the prescriptions in the Obstetrics and Gynecology clinic and 88.41% of the prescriptions in the Pediatric clinic were in accordance with the X General Hospital Formulary. The suitability analysis based on drug items showed that approximately 91.43% of the drug items in the Obstetrics and Gynecology clinic and 93.24% of the drug items in the Pediatric clinic were in accordance with the X General Hospital Formulary. Some drug items that were not in accordance with the formulary in the Obstetrics and Gynecology clinic were Utrogestan, Folamil Genio, and Folac, as they had not been requested by the attending physician, while in the Pediatric clinic, Nasacort, FG Troches, Opicort, Prednicort, Ceftik, and Salbuven were not in accordance due to being rarely prescribed (death stock), rarely prescribed in patient therapy (slow moving), and not requested by the attending physician.

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