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Dita Arccinirmala
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dorotea.arccinirmala@kalbe.co.id
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+6281905203065
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CDK@kalbe.co.id
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Redaksi CDK Gedung Kalbe, gedung 2 lantai 2 Jl. Letjen Suprapto Kav. 4. Cempaka Putih - Jakarta 10510
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INDONESIA
Cermin Dunia Kedokteran
Published by PT. Kalbe Farma Tbk.
ISSN : 0125913X     EISSN : 25032720     DOI : 10.55175
Core Subject : Health,
Cermin Dunia Kedokteran (CDK) is a Medical Journal published since 1974 and affiliated with PT Kalbe Farma Tbk. CDK is intended to help accommodate scientific publications and help increase and disseminate knowledge related to the development of medical science, pharmacy, and public health. CDK covers the disciplines of medicine, pharmacy, and health with several types of articles, namely: 1. Research 2. Literature review 3. Case report 4. Evidence-based case report (EBCR), systematic review 5. Other scientific articles Based on the SK Kemendikbudristek Nomor 152/E/KPT/2023, CDK has obtained Rank 4 (SINTA 4) for Scientific Journals.
Articles 1,276 Documents
Pemberian SABU (Serum Anti-Bisa Ular) untuk Kasus Gigitan Ular Awitan Lama dengan Komplikasi Disseminated Intravascular Coagulation (DIC) Dedy Kristofer Simangunsong; Hadiki Habib; Eirene Simbolon
Cermin Dunia Kedokteran Vol 51 No 3 (2024): Neurologi
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i3.941

Abstract

Background: Snakebite is a neglected disease in subtropical and tropical countries in Asia, Africa, and Latin America. Snakebite is one of the most common venomous animal bites in the world. Case: A 34-year-old male presented with a history of snakebite two days before with a swollen left gluteus and spontaneous gum bleeding. At the emergency room, the patient was fully conscious with blood pressure of 120/80 mmHg, temperature of 36.8oC, pulse rate of 80 beats per minute, and respiration rate of 18 times per minute. Blood studies showed prolonged prothrombin time (PT) and activated partial thromboplastin time (aPTT), leucocytosis, thrombocytopenia, low hemoglobin, and elevated renal function test. The patient's condition was improved after administration of anti-snake venom, vitamin K injection, transfusion of fresh frozen plasma and packed red cells. He was discharged after three days of hospital stays. Conclusion: Antivenom is the only specific antidote to snake venom; in Indonesia, there is only one local antivenom, commonly known as SABU (serum anti-bisa ular). Inappropriate use of antivenom should be strongly discouraged. Administration of the antivenom should be accompanied by preparedness for anaphylaxis risk.
Diagnosis dan Tata Laksana Perdarahan Batang Otak Primer Henry Hadianto
Cermin Dunia Kedokteran Vol 51 No 3 (2024): Neurologi
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i3.944

Abstract

Primary brainstem hemorrhage is an intracerebral hemorrhage that affects the brainstem, primarily caused by chronic hypertension. Clinical manifestations include decreased consciousness, motor weakness, respiratory problems, hyperthermia, and pupillary abnormalities. Diagnosis is with a head CT scan/MRI, bleeding was found in the mesencephalon, pontine, or medulla oblongata. Management is conservative with stabilization of vital signs, correction of hemostatic abnormalities, and intensive monitoring of neurological symptoms. Surgery is still controversial because of the lack of clinical and research evidence. The prognosis is generally grave depending on the degree of initial loss of consciousness, location, and volume of bleeding.
Komplikasi Okular pada Demam Dengue Haikal Hamas Putra Iqra; Rabiul Priyantono; Mia Purnama
Cermin Dunia Kedokteran Vol 51 No 1 (2024): Kedokteran Umum
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i1.945

Abstract

Ocular complications rarely occur in dengue fever, but were reported increasing. Several studies showed that cross-reactive antibody is responsible for ocular involvement in dengue. Blurred vision, followed by posterior segment involvement was seen in most cases. A simple examination in primary medical care such as the Amsler grid may detect scotoma and metamorphopsia. Early recognition of ocular involvement in dengue cases may prevent morbidity.
Clinical Characteristics, Chest X-Ray and Laboratory Findings of COVID-19 Patients in Leona Kefamenanu Hospital on 2021 : A retrospective study Luzelia Marta Sequeira Saldanha
Cermin Dunia Kedokteran Vol 50 No 12 (2023): Penyakit Dalam
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i12.947

Abstract

Introduction: COVID-19 can be life-threatening in older age group and those with comorbidities. This is a study on the clinical characteristics of COVID-19 patients in rural field hospitals in Indonesia. Method: A retrospective, non-experimental study on COVID-19 patients in LeonaKefamenanu Hospital, East Nusa Tenggara, Indonesia from January 2021 to December 2021. Multivariable logistic regression analysis was used to analyze the factors associated with severe COVID-19. Results: During the period, 153 patients were registered, 66 (43.1%) were male; mostly 40 to 59 years of age. The most common symptom was cough 144 (94.1%), followed by fever (n=105, 68.9%), fatigue (n=92, 60.1%), and nausea (n=80, 52.3%). Most patients had normal leukocyte, lymphocyte, and platelet counts; 17.6% of patients had hypokalemia, more frequently seen in severe cases (p<0.029). Most patients had an abnormality in their chest x-ray on admission (63.4%) and all were severe COVID-19. Multivariatelogistic regression analysis showed that age ≥60 years (OR = 8.98, 95%CI: 1.81–44.56, p =0.007) and dyspnea (OR = 16.83, 95%CI: 1.95–144.69, p =0.010) were independently associated with severe cases. Fatigue (OR = 4.606, 95%CI: 1.589–13.354, p <0.005) was also independently associatedwith disease deterioration. Conclusion: Age ≥60 years, fatigue, and dyspnea were associated with severe cases in Leona Kefamenanu Hospital, East Nusa Tenggara, Indonesia.
Flecainide sebagai Antiaritmia untuk Fibrilasi Atrium dan Aritmia Lainnya Lyon Clement
Cermin Dunia Kedokteran Vol 51 No 4 (2024): Oftalmologi
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i4.948

Abstract

Atrial fibrillation (AF) is one of the most common arrhythmias globally, and its prevalence is projected to increase, including in Indonesia. AF progression is related to lower quality of life and less responsive to therapy or even becomes irreversible. The progression of AF is significantly slower with the rhythm control strategy than with the rate control strategy alone. The options for therapy in Indonesia are limited to amiodarone and propafenone. Amiodarone is one of the most common drugs prescribed for AF rhythm control, but associated with multiple organ toxicities, thus increasing the risk of multiple side effects, especially on long-term usage, potentially leading to drug discontinuation. Flecainide is an antiarrhythmia with a favourable effectiveness and safety profile, especially for AF management, used for acute cardioversion, long-term rhythm control, and as a therapeutic modality for AF with preexcitation syndrome. Flecainide is a potential drug to address the unmet needs of amiodarone as a long-term management for AF.
Assessment of Knowledge, Attitude, and Practice (KAP) towards Hypertension in the Elderlies Rahmadia Kusumamardhika; Anis Puspita Utami; Hendro Darmawan
Cermin Dunia Kedokteran Vol 50 No 7 (2023): Kardiovaskular
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i7.951

Abstract

Introduction: The role of knowledge, attitude, and practice (KAP) in hypertension is crucial in controlling prevalence and preventing longterm complications against cardiovascular diseases. Method: Cross-sectional study on the elderlies with hypertension in Wijayakusuma Geriatric Outpatient Main Clinic, Bogor using valid KAP questionnaire. Results: The sample was 100 elderly hypertensive patients, 33% were male and 67% were female with an average of 67.43+5.13 years of age. As many as 75% of patients with controlled hypertension, 68% with obesity, 56% with hypertension less than 5 years, 54% had a family history of hypertension, and 2% had a history of smoking. The comorbidities were diabetes (40%), congestive heart disease (15%), and stroke (12%). The average knowledge is 81.88+16.8% (very good), the average attitude is 67.33+25.06% (good), and practice average 95+11.79% (very good). Knowledge is associated with education level (p=0.008) and hypertension duration (p=0.05). Attitudes are associated with controlled hypertension (p=0.008), whereas practice is related to age < 70 years (p=0.05). There is a relationship between knowledge and attitude (p=0.029). Conclusion: The role of KAP on hypertension in the elderly with hypertension are adequate, but can be improved.   Pendahuluan: Peran pengetahuan, sikap, dan perilaku (PSP) pada hipertensi penting untuk mengontrol prevalensi dan mencegah komplikasi jangka panjang. Metode: Studi cross-sectional menggunakan kuesioner yang valid terkait PSP pada pasien lanjut usia (lansia) hipertensi di poliklinik Klinik Utama Geriatri Wijayakusuma, Bogor. Hasil: Didapatkan 100 orang pasien terdiri dari 33% laki-laki dan 67% perempuan dengan rerata umur 67,43±5,13 tahun. Sebanyak 75% pasien dengan hipertensi terkontrol, 68% dengan obesitas, 56% dengan hipertensi di bawah 5 tahun, 54% memiliki riwayat hipertensi pada keluarga, dan 2% dengan riwayat merokok. Komorbid adalah diabetes (40%), penyakit jantung kongestif (15%), dan stroke (12%). Rerata pengetahuan adalah 81,88±16,8% (sangat baik), rerata sikap adalah 67,33±25,06% (baik), dan rerata perilaku adalah 95±11,79% (sangat baik). Pengetahuan berkaitan dengan tingkat pendidikan (p=0,008) dan durasi hipertensi (p=0,05). Sikap berkaitan dengan hipertensi terkontrol (p=0,008) dan terkait pada kelompok usia ≤ 70 tahun (p=0,05). Terdapat hubungan antara pengetahuan dan sikap (p=0,029). Simpulan: Peran PSP terkait hipertensi pada lansia sudah adekuat tetapi dapat ditingkatkan. 
Tinjauan atas Age-related Macular Degeneration Anak Agung Fridami Dewi
Cermin Dunia Kedokteran Vol 50 No 7 (2023): Kardiovaskular
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i7.953

Abstract

Age-related macular degeneration (AMD) merupakan penyakit degeneratif makula yang mengakibatkan gangguan penglihatan sentral pada usia lanjut. AMD yang didapatkan pada sekitar 5,8% individu dengan kebutaan, merupakan penyebab kebutaan keempat terbanyak di dunia. Faktor risiko AMD meliputi usia, genetik, merokok, dan nutrisi. AMD diklasifikasikan menjadi AMD non-neovaskular (dry) dan neovaskular (wet). Pada tahap awal AMD sering tidak bergejala, pada tahap lanjut dapat ditemukan hilang penglihatan sentral disertai distorsi visual dengan gambaran drusen, geographic atrophy, atau neovaskularisasi koroid pada pemeriksaan fundus. Pencitraan retina diperlukan untuk menentukan tata laksana sesuai derajat penyakit. Penanganan AMD non-neovaskular saat ini ditekankan pada observasi dan kemampuan pasien untuk mengenali perubahan fungsi visual serta deteksi dini neovaskularisasi koroid. Modifikasi gaya hidup, seperti berhenti merokok dan suplementasi nutrisi, dapat dilakukan untuk mencegah progresivitas AMD. Terapi anti-VEGF (vascular endothelial growth factor) saat ini merupakan pilihan untuk tata laksana AMD neovaskular.   Age-related macular degeneration (AMD) is a macular degenerative disease causing impaired central vision in elderly. AMD occurs in approximately 5.8% of individuals with blindness; it is the fourth leading cause of blindness in the world. The risk factors of AMD include age, genetics, smoking, and nutrition. AMD is classified into non-neovascular (dry) and neovascular (wet) AMD. Early AMD is often asymptomatic, loss of central vision with visual distortion can happen in the later stages. Drusen, geographic atrophy, or choroidal neovascularization can be observed in fundus examination. Retinal imaging is needed to determine management according to the stage of the disease. Current management of non-neovascular AMD is emphasized through observation and the patient’s ability to recognize changes in visual function as well as early detection of choroidal neovascularization. Lifestyle modifications such as smoking cessation and nutritional supplementation can prevent the progression of AMD. Anti-VEGF (vascular endothelial growth factor) therapy is currently an option for the management of neovascular AMD.
Efek Neurologis Hipernatremia Carmenita; Budi Riyanto Wreksoatmodjo
Cermin Dunia Kedokteran Vol 50 No 7 (2023): Kardiovaskular
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i7.954

Abstract

Aktivitas otak memerlukan kondisi yang optimal, termasuk lingkungan elektrolit yang ideal. Salah satu elektrolit utama dalam tubuh yang juga penting untuk aktivitas otak adalah natrium. Hipernatremia yang tidak terkoreksi dapat menyebabkan berbagai manifestasi klinis yang bervariasi mulai dari rasa haus, kelemahan, eksitabilitas neuromuskular, hiperrefleks, letargi, confusion, kejang, atau koma. Oleh karena itu, penyebab, gejala, diagnosis, dan penanganan yang tepat perlu untuk mencegah penurunan kualitas hidup pasien.   Brain activities need optimal conditions, including an ideal electrolyte environment. One of the main electrolytes in the body that is also essential for brain activity is sodium. Uncorrected hypernatremia may manifest in symptoms of thirst, weakness, neuromuscular excitability, hyperreflexia, lethargy, confusion, seizure, and coma. Therefore, the causes, symptoms, diagnosis, and appropriate treatment are necessary to prevent a decline in the patient’s quality of life.
Persalinan En Caul pada Kehamilan Kembar Raymond Surya; Ekarini Aryasatiani
Cermin Dunia Kedokteran Vol 50 No 7 (2023): Kardiovaskular
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i7.955

Abstract

Pendahuluan: Persalinan en caul merupakan persalinan dengan bayi dilahirkan di dalam cairan amnion yang utuh. Kasus: Seorang wanita berusia 34 tahun dengan gravida 4 para 3 hamil 37 minggu datang ke IGD dengan keluhan keluar air-air sejak 3 jam sebelum masuk RS. Pemeriksaan menunjukkan kehamilan kembar presentasi lintang-lintang. Pasien diputuskan dilahirkan secara operasi seksio sesarea atas indikasi ketuban pecah dan posisi bayi lintang. Bayi pertama yang dilahirkan adalah laki-laki dengan berat 2.600 gram skor Apgar (Apgar score/AS) 7/9. Bayi kedua dilahirkan secara en caul dengan jenis kelamin laki-laki dengan berat 2.400 gram AS 7/9. Simpulan: Persalinan en caul lebih menguntungkan pada persalinan prematur, dan dapat juga dilakukan pada persalinan cukup bulan tanpa efek negatif pada bayi.   Introduction: En caul birth is a delivery with an intact amniotic membrane covering a newborn’s body. Case: A 34-year-old gravida 4 para 3, 37 weeks of gestation presented to the Emergency Department due to membrane rupture 3 hours before admission. The examination revealed a twin pregnancy with a transverse-transverse presentation. A cesarean section was performed because of transverse presentation and membrane rupture. The first baby boy was born with 2,600 grams bodyweight and Apgar score (AS) of 7/9. The second baby boy was born en caul with 2,400 grams bodyweight and AS of 7/9. Conclusion: En caul birth is possible in preterm delivery, can also be performed in full-term labor without negative effects on the baby.
Leiner’s Disease (Erythroderma Desquamativum) in a Baby Boy Ayudhia Giovanny Halim; Kun Anggi Yunanto; I Gede Mahardhita
Cermin Dunia Kedokteran Vol 50 No 7 (2023): Kardiovaskular
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i7.957

Abstract

Background: Leiner’s disease (erythroderma desquamativum) is a disorder in infants; it is a complication of seborrheic dermatitis with universal and scaly erythema (erythroderma). The case is a baby boy aged 1 month 18 days with white scaly skin for 10 days and fever for 3 days prior to hospital admission. The prognosis is good with the risk of severe infections such as pneumonia, meningitis, and sepsis if not properly treated.   Latar Belakang: Penyakit Leiner (erythroderma desquamativum) adalah gangguan pada bayi yang merupakan komplikasi dermatitis seboroik; biasanya ditemukan eritema universal dan skuama (eritroderma). Kasus pada seorang bayi laki-laki berumur 1 bulan 18 hari dengan kulit kemerahan serta bersisik putih kekuningan sejak 10 hari sebelum masuk RS dan demam selama 3 hari. Prognosis baik dengan risiko infeksi berat seperti pneumonia, meningitis, dan sepsis jika tidak diterapi dengan baik.

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