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INDONESIA
Cermin Dunia Kedokteran
Published by PT. Kalbe Farma Tbk.
ISSN : 0125913X     EISSN : 25032720     DOI : 10.55175
Core Subject : Health,
Health Professions
Cermin Dunia Kedokteran (CDK) is a Medical Journal published since 1974 and affiliated with PT Kalbe Farma Tbk. CDK is intended to help accommodate scientific publications and help increase and disseminate knowledge related to the development of medical science, pharmacy, and public health. CDK covers the disciplines of medicine, pharmacy, and health with several types of articles, namely: 1. Research 2. Literature review 3. Case report 4. Evidence-based case report (EBCR), systematic review 5. Other scientific articles Based on the SK Kemendikbudristek Nomor 152/E/KPT/2023, CDK has obtained Rank 4 (SINTA 4) for Scientific Journals.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 1,371 Documents
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Kesadaran Orang Tua terhadap Aplikasi Berbasis Ponsel Pintar untuk Anak-Anak Tunanetra dan Tuli di Yogyakarta, Indonesia: Penelitian Pratiwi, Karina Satyani; Arjana, Adika Zhulhi; Ratnaningrum, Ayu Yunita; Sabana, Manusama Hasan; Chamidah, Atien Nur
Cermin Dunia Kedokteran Vol 53 No 05 (2026): Mei 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i05.1823

Abstract

Introduction: Smartphone-based applications (SBA) are currently available to help children with visual impairment (VI) and blindness progress to the next level of learning. This study aims to explore parental awareness of SBA to support the learning process of their visually impaired children. Methods: A cross-sectional study involving 27 children with VI and blindness. Parents were sent a questionnaire to be completed. The 20-item questionnaire measured the history of their children’s general and eye health, and SBA awareness and use, if any. Children were examined for general health and current eye conditions. Results: Blindness was 92.9%. The most common cause of blindness was retinopathy of prematurity. The majority went to a special school for the blind. Parents’ education level was mostly high school graduates. Only 22.2% parents were aware of the existence of SBA for children with VI and blindness. Conclusion: Parental awareness regarding smartphone-based applications (SBA) for children with VI and blindness was low.
Penyerapan I-131 yang Tidak Disengaja pada Karsinoma Ovarium pada Seorang Pasien dengan Karsinoma Tiroid yang Terdiferensiasi: Laporan Kasus: Laporan Kasus Sihombing, Amordekhai Imvan Parlindungan; Nugrahadi, Trias; Kartamihardja, Achmad Hussein Sundawa
Cermin Dunia Kedokteran Vol 53 No 05 (2026): Mei 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i05.1919

Abstract

Introduction: Radioactive iodine (I-131) therapy is an essential component in the management of differentiated thyroid carcinoma (DTC) following total thyroidectomy. Post-therapy whole-body scintigraphy (PT-WBS) with I-131 aims to detect residual thyroid tissue, recurrence, or metastatic spread. Radioiodine uptake outside the thyroid region may suggest metastases or false-positive findings, thus requiring careful interpretation. Case: A 47-year-old woman with differentiated thyroid carcinoma (DTC) underwent I-131 therapy. The PT-WBS and single photon emission computed tomography/computed tomography (SPECT/CT) revealed no I-131 uptake in the thyroid bed, but instead showed unexpected I-131 uptake in bilateral ovarian masses. Subsequent histopathological and immunohistochemical evaluation after total hysterectomy with bilateral salpingo-oophorectomy confirmed that the masses were ovarian carcinoma. Discussion: Radioiodine uptake in ovarian carcinoma is extremely rare and may be attributed to the expression of the sodium-iodide symporter (NIS) in the ovarian surface epithelium (OSE). Other contributing factors may include increased tumor vascularity, local inflammation, and enhanced capillary permeability that facilitate iodine retention. Conclusion: This case highlights the importance of considering non-thyroidal malignancies in the interpretation of PT-WBS findings, particularly when atypical uptake is observed.
Persepsi Mahasiswa terhadap Simulasi Pelatihan Resusitasi Jantung Paru dengan Media Virtual Reality di Fakultas Kedokteran Universitas Wahid Hasyim, Semarang, Indonesia: Penelitian Wulandari, Nur Arfa; Herlambang, Penggalih Mahardika; Rido Muid, Rido Muid; Annanto, Gilar Pandu; Firmansyah, Erik; Prasetyo, Sandif
Cermin Dunia Kedokteran Vol 53 No 05 (2026): Mei 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i05.1929

Abstract

Background: Cardiac arrest is a medical emergency requiring immediate action to prevent sudden death. Virtual Reality (VR) technology has been introduced to enhance the effectiveness of cardiopulmonary resuscitation (CPR) training. This study aims to evaluate students’ perceptions of using VR in CPR training simulations at the Faculty of Medicine, Wahid Hasyim University, Semarang. Methods: This study used a cross-sectional design with a descriptive quantitative approach. A total of 30 first-semester students were selected using a purposive sampling technique. Data were collected using a Likert-scale questionnaire based on the Technology Acceptance Model (TAM) that included Perceived Usefulness (PU), Perceived Ease of Use (PEOU), Attitude Toward Using (ATU), and Behavioral Intention to Use (BIU), as well as variables of simulation effectiveness and VR technical difficulty. Data were analyzed descriptively. Results: The average PU score of 4.15 and PEOU score of 4.20 reflect positive perceptions of the added value and ease of use of VR. ATU scored 4.39, and BIU scored 4.08, indicating positive attitudes and strong intentions to continue using VR in CPR training. However, some students reported technical challenges, with an average score of 2.67. Conclusion: Students demonstrated positive perceptions of using VR in CPR training simulations, with high scores across all TAM aspects.
Hubungan antara Obesitas, Pola Makan, dan Nyeri Saat Buang Air Besar pada Anak dengan Konstipasi Fungsional: Tinjauan Literatur: Tinjauan Pustaka Nuridah, Ayu Lilyana; Putri, Awalya Rahma; Anggraeni, Yunita Dewi; Shodikin, Muhammad Ali
Cermin Dunia Kedokteran Vol 53 No 05 (2026): Mei 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i05.1949

Abstract

Background: Functional constipation is defined as delayed or difficult bowel movements lasting ≥2 weeks that cause the patient distress. This study aims to examine the relationship between obesity, dietary patterns, and defecation pain with the incidence of functional constipation in children. Methods: A literature review was conducted using predefined keywords from data sources Google Scholar, PubMed, and ScienceDirect. Inclusion criteria included open-access articles published between 2014 and 2024. A total of 9 articles that met the criteria were further analyzed. Results: Functional constipation is associated with several risk factors, including obesity, unhealthy dietary patterns, and defecation pain. Some studies showed a positive correlation between obesity and functional constipation, although the results varied and were not always statistically significant. Low-fiber, high-fat diets have been reported to impair intestinal motility. Pain during defecation may reinforce the behavior of stool withholding, which ultimately worsens constipation symptoms. Conclusion: This review highlights the importance of factors such as obesity, dietary habits, and defecation pain in preventing and managing functional constipation in children.
Hernia Inguinal Lateral pada Seorang Anak Berusia 13 Tahun: Laporan Kasus: Laporan Kasus Putri, Felicia Vivian Nowi; Leifon, Dave Edgar; Sharon, Sonya Hedva; Soeselo, Daniel Ardian
Cermin Dunia Kedokteran Vol 53 No 05 (2026): Mei 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i05.1970

Abstract

Background: Indirect inguinal hernia, particularly in children, is typically due to the failure of the processus vaginalis closure and is located lateral to the inferior epigastric vessels. Hernias are generally found in children aged 0-5 years, in premature infants, and in elderly individuals aged 75-80 years. In this case, however, the patient is 13 years old, an age that is considered uncommon for the manifestation of a congenital hernia. Case: A 13-year-old boy presented with a one-month history of an intermittent left scrotal bulge. Physical examination in the standing position revealed an elongated lump extending from the left inguinal region down to the left scrotum, which became more prominent during the Valsalva maneuver. The lump was spontaneously reduced when the patient was lying down. The lump had a soft consistency, welldefined margins, a smooth surface, and was reducible on pressure. Two similar-sized testes were palpable in the scrotum. The diagnosis was left indirect inguinal hernia; the patient underwent herniotomy without complications. Postoperative recovery was uneventful with no residual complaints. Discussion: Indirect inguinal hernias in children are generally caused by the persistence of the processus vaginalis and are characterized by a lump that appears when intra-abdominal pressure increases. Diagnosis is clinical, and the definitive treatment is surgery (herniotomy) due to the higher risk of incarceration. Conclusion: This case highlights the importance of early detection and appropriate management in the pediatric population to prevent complications such as incarceration or strangulation.
Efektivitas Suplementasi Lutein dan Zeaxanthin terhadap Perkembangan Atrofi Geografis dan Ketajaman Penglihatan pada Degenerasi Makula Terkait Usia: Tinjauan Sistematis Berdasarkan Uji Klinis: Tinjauan Sistematik Kesumaputri, Komang Diah Kurnia; Dwipayani, Ni Made; Wibawa, I Made Dwi Surya; Agrasidi, Putu Anindya; -, Felicia
Cermin Dunia Kedokteran Vol 53 No 05 (2026): Mei 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i05.2155

Abstract

Introduction: Geographic atrophy (GA) is an advanced form of dry age-related macular degeneration (AMD) that can cause severe central vision loss if its progression extends to the foveal area. Currently, therapeutic options for GA remain limited, with safety profiles requiring further evaluation. Lutein and zeaxanthin, as the main components of the Age-Related Eye Disease Study (AREDS2) formula, have become the focus of current research. Both are antioxidants concentrated in the macula, which exert protective effects on retinal structures and reduce oxidative stress. This systematic review aims to evaluate the effectiveness of oral lutein and zeaxanthin supplementation on GA progression and visual acuity in AMD patients. Methods: Literature searches were conducted across four biomedical databases based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol. A total of four studies met the inclusion criteria and were analyzed qualitatively. Results: The analysis showed that oral supplementation of lutein (10 mg/day) and zeaxanthin (2 mg/day) may reduce the progression of non-central GA and stabilize or improve visual acuity in patients with AMD. Lutein at doses of 10 mg and 20 mg demonstrated similar effectiveness in improving visual acuity through an increase in macular pigment optical density (MPOD). Conclusion: Based on the findings of this systematic review, oral supplementation with lutein (10 mg/day) and zeaxanthin (2 mg/day), as incorporated in the AREDS2 formulation, appears to slow the progression of non-central GA and preserve foveal integrity (foveal sparing). Further long-term studies are required to confirm the clinical benefits and long-term safety.
Pendekatan Klinis Sindrom Takotsubo: Tinjauan Pustaka Pramudya, Ricky
Cermin Dunia Kedokteran Vol 53 No 06 (2026): Juni 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i06.1349

Abstract

Takotsubo syndrome (TTS) or cardiomyopathy due to stress is defined as a syndrome of acute systolic and diastolic dysfunction of the left ventricle, usually associated with emotional or profound physical stress. The incidence of Takotsubo syndrome has increased dramatically during the COVID-19 pandemic, which is closely related to psychological stressors such as social isolation, financial problems, and anxiety. Increased sympathetic stimulation with massive catecholamine release plays a major role in the pathogenesis of Takotsubo cardiomyopathy. An accurate history of the emotional and physical events preceding the onset of symptoms is the most important diagnostic tool. In the acute phase, most complaints are typical chest pain similar to myocardial infarction, while others come with symptoms of heart failure, such as dyspnea, orthopnea and/or acute pulmonary edema or syncope. An important clinical marker of Takotsubo cardiomyopathy is an increase in N-terminal prohormone of brain natriuretic peptide (NT proBNP), which has been shown to be directly related to elevated blood catecholamine concentrations, a marker of sympathetic overreaction, and the severity of left ventricular dysfunction with associated systemic complications, such as pulmonary edema. Supportive and symptomatic treatment should be provided in the acute phase. Patients with Takotsubo cardiomyopathy have a good prognosis, with left ventricular function recovering within days and fully recovering within 3–4 weeks.
Perbedaan Kelembapan Kulit Sebelum dan Sesudah Pemberian Suplemen Kolagen pada Mahasiswi Fakultas Kedokteran di Jakarta: Penelitian Septiani Wibowo, Jessie; Ekowati, Ana Lucia; Wijaya, Lorettha; Dewi, Kardiana Purnama
Cermin Dunia Kedokteran Vol 53 No 06 (2026): Juni 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i06.1579

Abstract

Introduction: Adequate nutrition, including collagen supplements and the use of moisturizers, can improve skin hydration. This study aims to determine the effects of collagen supplements and several factors such as history of keratosis and atopic dermatitis, sun exposure, bathing habits, and water intake on skin moisture. Methods: This is a descriptive-analytical study with consecutive sampling involving 29 female students aged 19–21 years who met the inclusion and exclusion criteria. The participants were given collagen supplements for 12 weeks, and skin moisture was measured at weeks 0, 4, 8, and 12 using the skin analyzer SK-8 on the upper left arm. Results: This study showed that the average skin moisture level was 32.02% before supplementation and 68.37% after supplementation, indicating a significant difference (p < 0.001). Factors such as history of keratosis and atopic dermatitis, sun exposure, bathing habits, and water intake were not related to skin moisture. Conclusion: These findings suggest that collagen supplementation may contribute to improved skin hydration under the studied conditions.
Hipertermia Maligna: Tinjauan Pustaka: Tinjauan Pustaka Pandrya, Carla Oktaviani; Anderson Surya, Kevin
Cermin Dunia Kedokteran Vol 53 No 06 (2026): Juni 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i06.1746

Abstract

Malignant hyperthermia (MH) is a life-threatening syndrome triggered by inhaled anesthetics and depolarizing muscle relaxants like succinylcholine, leading to uncontrolled skeletal muscle hypermetabolism. This condition is marked by massive calcium release from the endoplasmic reticulum, causing muscle rigidity, increased temperature, and metabolic disturbances. The genetic basis of MH is linked to mutations in the CACNA1S gene, which encodes a subunit of the dihydropyridine receptor (DHPR), which is essential to muscle calcium regulation. The condition is often triggered during surgeries requiring general or regional anesthesia, particularly in individuals with a family history of MH. Clinical manifestations may include hypercapnia, tachycardia, acidosis, rhabdomyolysis, and multi-organ dysfunction. Early diagnosis remains challenging because MH may resemble other hypermetabolic conditions and can progress rapidly if left untreated. Treatment involves the administration of dantrolene, a post-synaptic muscle relaxant that reduces excitation-contraction coupling (ECC) and mitigates hypermetabolism. Early recognition and prompt dantrolene administration are vital for successful management.
Eksplorasi Tingkat Stres dan Strategi Coping Mahasiswa Kedokteran Tingkat Akhir yang Mengalami Stagnasi dalam Penyusunan Skripsi: Studi Kualitatif di FK Universitas Tanjungpura: Penelitian Lo, Anggraini Millennia; Yuniarni, Desni; Armyanti, Ita
Cermin Dunia Kedokteran Vol 53 No 06 (2026): Juni 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i06.1752

Abstract

Introduction: Final-year medical students often face significant academic pressure during the thesis-writing process, which can lead to stress and stagnation in academic progress. This stagnation reflects the tension between academic demands, internal pressures, and environmental factors that affect students’ psychological balance. Unmanaged stress may cause emotional, physical, and cognitive strain, as well as the use of maladaptive coping strategies that hinder academic productivity. This study aims to explore the levels of stress, stress responses, the nature of stress, and coping strategies among final-year medical students experiencing stagnation in thesis completion. Method: This research employed a qualitative, phenomenological approach to understand the subjective experiences and meanings of academic stress among medical students. Participants were selected through purposive sampling, comprising 10 final-year medical students who met the criteria for thesis stagnation. Data were collected through semi-structured in-depth interviews and analyzed using thematic analysis to identify patterns in stress experiences and coping mechanisms. Results: The findings indicate that most participants experienced moderate to severe stress, reflected in emotional responses (anxiety, frustration, and loss of motivation), physical symptoms (fatigue, sleep disturbance, and psychosomatic complaints), and cognitive impacts (difficulty concentrating, overthinking, and procrastination). The nature of stress varied between positive stress (eustress), which enhanced motivation, and negative stress (distress), which hindered progress. Coping strategies were classified as adaptive (seeking social support, prayer, and time management) and maladaptive (avoidance, withdrawal, and delay). Institutional barriers, including bureaucratic constraints, academic hierarchy, and limited psychosocial support, were found to exacerbate thesis stagnation. Conclusion: High stress levels among final-year medical students are associated with complex stress responses and a tendency toward maladaptive coping when academic and emotional support is lacking. Therefore, medical institutions need to implement time and stress management training, psychosocial mentoring, and an early academic warning system to foster a supportive learning environment and prevent stress from escalating during the thesis-writing process.

Page 134 of 138 | Total Record : 1371

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