cover
Contact Name
Dita Arccinirmala
Contact Email
dorotea.arccinirmala@kalbe.co.id
Phone
+6281905203065
Journal Mail Official
CDK@kalbe.co.id
Editorial Address
Redaksi CDK Gedung Kalbe, gedung 2 lantai 2 Jl. Letjen Suprapto Kav. 4. Cempaka Putih - Jakarta 10510
Location
Unknown,
Unknown
INDONESIA
Cermin Dunia Kedokteran
Published by PT. Kalbe Farma Tbk.
ISSN : 0125913X     EISSN : 25032720     DOI : 10.55175
Core Subject : Health,
Cermin Dunia Kedokteran (CDK) is a Medical Journal published since 1974 and affiliated with PT Kalbe Farma Tbk. CDK is intended to help accommodate scientific publications and help increase and disseminate knowledge related to the development of medical science, pharmacy, and public health. CDK covers the disciplines of medicine, pharmacy, and health with several types of articles, namely: 1. Research 2. Literature review 3. Case report 4. Evidence-based case report (EBCR), systematic review 5. Other scientific articles Based on the SK Kemendikbudristek Nomor 152/E/KPT/2023, CDK has obtained Rank 4 (SINTA 4) for Scientific Journals.
Articles 1,336 Documents
Kesadaran Orang Tua terhadap Aplikasi Berbasis Ponsel Pintar untuk Anak-Anak Tunanetra dan Tuli di Yogyakarta, Indonesia: Penelitian Pratiwi, Karina Satyani; Arjana, Adika Zhulhi; Ratnaningrum, Ayu Yunita; Sabana, Manusama Hasan; Chamidah, Atien Nur
Cermin Dunia Kedokteran Vol 53 No 05 (2026): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i05.1823

Abstract

Introduction: Smartphone-based applications (SBA) are currently available to help children with visual impairment (VI) and blindness progress to the next level of learning. This study aims to explore parental awareness of SBA to support the learning process of their visually impaired children. Methods: A cross-sectional study involving 27 children with VI and blindness. Parents were sent a questionnaire to be completed. The 20-item questionnaire measured the history of their children’s general and eye health, and SBA awareness and use, if any. Children were examined for general health and current eye conditions. Results: Blindness was 92.9%. The most common cause of blindness was retinopathy of prematurity. The majority went to a special school for the blind. Parents’ education level was mostly high school graduates. Only 22.2% parents were aware of the existence of SBA for children with VI and blindness. Conclusion: Parental awareness regarding smartphone-based applications (SBA) for children with VI and blindness was low.
Penyerapan I-131 yang Tidak Disengaja pada Karsinoma Ovarium pada Seorang Pasien dengan Karsinoma Tiroid yang Terdiferensiasi: Laporan Kasus: Laporan Kasus Sihombing, Amordekhai Imvan Parlindungan; Nugrahadi, Trias; Kartamihardja, Achmad Hussein Sundawa
Cermin Dunia Kedokteran Vol 53 No 05 (2026): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i05.1919

Abstract

Introduction: Radioactive iodine (I-131) therapy is an essential component in the management of differentiated thyroid carcinoma (DTC) following total thyroidectomy. Post-therapy whole-body scintigraphy (PT-WBS) with I-131 aims to detect residual thyroid tissue, recurrence, or metastatic spread. Radioiodine uptake outside the thyroid region may suggest metastases or false-positive findings, thus requiring careful interpretation. Case: A 47-year-old woman with differentiated thyroid carcinoma (DTC) underwent I-131 therapy. The PT-WBS and single photon emission computed tomography/computed tomography (SPECT/CT) revealed no I-131 uptake in the thyroid bed, but instead showed unexpected I-131 uptake in bilateral ovarian masses. Subsequent histopathological and immunohistochemical evaluation after total hysterectomy with bilateral salpingo-oophorectomy confirmed that the masses were ovarian carcinoma. Discussion: Radioiodine uptake in ovarian carcinoma is extremely rare and may be attributed to the expression of the sodium-iodide symporter (NIS) in the ovarian surface epithelium (OSE). Other contributing factors may include increased tumor vascularity, local inflammation, and enhanced capillary permeability that facilitate iodine retention. Conclusion: This case highlights the importance of considering non-thyroidal malignancies in the interpretation of PT-WBS findings, particularly when atypical uptake is observed.
Persepsi Mahasiswa terhadap Simulasi Pelatihan Resusitasi Jantung Paru dengan Media Virtual Reality di Fakultas Kedokteran Universitas Wahid Hasyim, Semarang, Indonesia: Penelitian Wulandari, Nur Arfa; Herlambang, Penggalih Mahardika; Rido Muid, Rido Muid; Annanto, Gilar Pandu; Firmansyah, Erik; Prasetyo, Sandif
Cermin Dunia Kedokteran Vol 53 No 05 (2026): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i05.1929

Abstract

Background: Cardiac arrest is a medical emergency requiring immediate action to prevent sudden death. Virtual Reality (VR) technology has been introduced to enhance the effectiveness of cardiopulmonary resuscitation (CPR) training. This study aims to evaluate students’ perceptions of using VR in CPR training simulations at the Faculty of Medicine, Wahid Hasyim University, Semarang. Methods: This study used a cross-sectional design with a descriptive quantitative approach. A total of 30 first-semester students were selected using a purposive sampling technique. Data were collected using a Likert-scale questionnaire based on the Technology Acceptance Model (TAM) that included Perceived Usefulness (PU), Perceived Ease of Use (PEOU), Attitude Toward Using (ATU), and Behavioral Intention to Use (BIU), as well as variables of simulation effectiveness and VR technical difficulty. Data were analyzed descriptively. Results: The average PU score of 4.15 and PEOU score of 4.20 reflect positive perceptions of the added value and ease of use of VR. ATU scored 4.39, and BIU scored 4.08, indicating positive attitudes and strong intentions to continue using VR in CPR training. However, some students reported technical challenges, with an average score of 2.67. Conclusion: Students demonstrated positive perceptions of using VR in CPR training simulations, with high scores across all TAM aspects.
Hubungan antara Obesitas, Pola Makan, dan Nyeri Saat Buang Air Besar pada Anak dengan Konstipasi Fungsional: Tinjauan Literatur: Tinjauan Pustaka Nuridah, Ayu Lilyana; Putri, Awalya Rahma; Anggraeni, Yunita Dewi; Shodikin, Muhammad Ali
Cermin Dunia Kedokteran Vol 53 No 05 (2026): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i05.1949

Abstract

Latar Belakang: Konstipasi fungsional didefinisikan sebagai keterlambatan atau kesulitan buang air besar yang berlangsung selama ≥2 minggu dan menimbulkan distres. Penelitian ini bertujuan untuk melihat hubungan antara obesitas, pola makan, dan nyeri defekasi terhadap kejadian konstipasi fungsional pada anak. Metode: Tinjauan literatur dari sumber data Google Scholar, PubMed, dan ScienceDirect menggunakan kata kunci yang sudah ditentukan. Kriteria inklusi mencakup artikel akses terbuka yang terbit pada tahun 2014–2024. Sebanyak 9 artikel yang memenuhi kriteria dianalisis lebih lanjut. Hasil: Konstipasi fungsional berhubungan dengan beberapa faktor risiko, termasuk obesitas, pola makan yang tidak sehat, dan nyeri defekasi. Beberapa studi menunjukkan korelasi positif antara obesitas dan konstipasi fungsional, meskipun masih bervariasi dan tidak selalu signifikan. Konsumsi makanan rendah serat dan tinggi lemak dilaporkan berkontribusi terhadap gangguan motilitas usus. Nyeri saat defekasi dapat memperkuat perilaku menahan feses, yang pada akhirnya memperburuk gejala konstipasi. Simpulan: Tinjauan ini menegaskan pentingnya mempertimbangkan faktor obesitas, pola makan, dan nyeri defekasi untuk pencegahan dan tatalaksana konstipasi fungsional pada anak.
Hernia Inguinal Lateral pada Seorang Anak Berusia 13 Tahun: Laporan Kasus: Laporan Kasus Putri, Felicia Vivian Nowi; Leifon, Dave Edgar; Sharon, Sonya Hedva; Soeselo, Daniel Ardian
Cermin Dunia Kedokteran Vol 53 No 05 (2026): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i05.1970

Abstract

Latar belakang: Hernia inguinalis indirek, khususnya pada anak, terjadi karena kegagalan penutupan processus vaginalis dan terletak lateral terhadap pembuluh epigastrika inferior. Hernia umumnya didapatkan pada usia 0–5 tahun, pada bayi prematur, serta pada lansia usia 75–80 tahun. Namun demikian, pasien pada kasus ini berusia 13 tahun, usia yang tergolong tidak umum untuk manifestasi hernia kongenital. Kasus: Anak laki-laki 13 tahun dengan keluhan benjolan hilang timbul pada skrotum kiri sejak satu bulan yang lalu. Pemeriksaan fisik saat posisi berdiri terlihat benjolan lonjong dari inguinal kiri hingga skrotum kiri yang makin menonjol dengan Valsalva test. Saat berbaring, benjolan bisa dimasukkan kembali. Benjolan teraba kenyal, berbatas tegas, permukaan licin, dan reponibel saat ditekan. Testis teraba 2 buah dengan ukuran sama di skrotumnya. Diagnosis hernia inguinalis indirek sinistra; pasien menjalani prosedur herniotomi tanpa komplikasi. Pemulihan pascaoperasi baik tanpa keluhan lanjutan. Pembahasan: Hernia inguinalis indirek pada anak umumnya disebabkan oleh persistensi processus vaginalis dan ditandai benjolan yang muncul saat peningkatan tekanan intraabdomen. Diagnosis bersifat klinis dan tata laksana definitif adalah pembedahan (herniotomi) karena risiko inkarserasi lebih tinggi. Simpulan: Laporan kasus ini menekankan pentingnya deteksi dini dan intervensi tepat pada populasi anak, untuk mencegah komplikasi seperti inkarserasi atau strangulasi.
Efektivitas Suplementasi Lutein dan Zeaxanthin terhadap Perkembangan Atrofi Geografis dan Ketajaman Penglihatan pada Degenerasi Makula Terkait Usia: Tinjauan Sistematis Berdasarkan Uji Klinis: Tinjauan Sistematik Kesumaputri, Komang Diah Kurnia; Dwipayani, Ni Made; Wibawa, I Made Dwi Surya; Agrasidi, Putu Anindya; -, Felicia
Cermin Dunia Kedokteran Vol 53 No 05 (2026): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i05.2155

Abstract

Introduction: Geographic atrophy (GA) is an advanced form of dry age-related macular degeneration (AMD) that can cause severe central vision loss if its progression extends to the foveal area. Currently, therapeutic options for GA remain limited, with safety profiles requiring further evaluation. Lutein and zeaxanthin, as the main components of the Age-Related Eye Disease Study (AREDS2) formula, have become the focus of current research. Both are antioxidants concentrated in the macula, which exert protective effects on retinal structures and reduce oxidative stress. This systematic review aims to evaluate the effectiveness of oral lutein and zeaxanthin supplementation on GA progression and visual acuity in AMD patients. Methods: Literature searches were conducted across four biomedical databases based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol. A total of four studies met the inclusion criteria and were analyzed qualitatively. Results: The analysis showed that oral supplementation of lutein (10 mg/day) and zeaxanthin (2 mg/day) may reduce the progression of non-central GA and stabilize or improve visual acuity in patients with AMD. Lutein at doses of 10 mg and 20 mg demonstrated similar effectiveness in improving visual acuity through an increase in macular pigment optical density (MPOD). Conclusion: Based on the findings of this systematic review, oral supplementation with lutein (10 mg/day) and zeaxanthin (2 mg/day), as incorporated in the AREDS2 formulation, appears to slow the progression of non-central GA and preserve foveal integrity (foveal sparing). Further long-term studies are required to confirm the clinical benefits and long-term safety.

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