cover
Contact Name
Dita Arccinirmala
Contact Email
dorotea.arccinirmala@kalbe.co.id
Phone
+6281905203065
Journal Mail Official
CDK@kalbe.co.id
Editorial Address
Redaksi CDK Gedung Kalbe, gedung 2 lantai 2 Jl. Letjen Suprapto Kav. 4. Cempaka Putih - Jakarta 10510
Location
Unknown,
Unknown
INDONESIA
Cermin Dunia Kedokteran
Published by PT. Kalbe Farma Tbk.
ISSN : 0125913X     EISSN : 25032720     DOI : 10.55175
Core Subject : Health,
Cermin Dunia Kedokteran (CDK) is a Medical Journal published since 1974 and affiliated with PT Kalbe Farma Tbk. CDK is intended to help accommodate scientific publications and help increase and disseminate knowledge related to the development of medical science, pharmacy, and public health. CDK covers the disciplines of medicine, pharmacy, and health with several types of articles, namely: 1. Research 2. Literature review 3. Case report 4. Evidence-based case report (EBCR), systematic review 5. Other scientific articles Based on the SK Kemendikbudristek Nomor 152/E/KPT/2023, CDK has obtained Rank 4 (SINTA 4) for Scientific Journals.
Articles 1,276 Documents
Peran Probiotik pada Terapi Akne Vulgaris Maichika Susanto
Cermin Dunia Kedokteran Vol 50 No 7 (2023): Kardiovaskular
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i7.958

Abstract

Akne vulgaris merupakan gangguan inflamasi kronis unit kelenjar pilosebasea. Probiotik merupakan mikroorganisme hidup yang dapat menguntungkan tubuh. Teori gut-brain-skin oleh Stokes dan Pilssbury pada tahun 1930 menunjukkan hubungan antara saluran pencernaan, otak, dan kulit. Probiotik berpengaruh baik pada tata laksana akne vulgaris melalui efek anti inflamasinya.   Acne vulgaris is a chronic inflammatory disorder of the pilosebaceous unit. Probiotics are live microorganisms with beneficial effects. The gutbrain-skin theory first described by Stokes and Pillsbury in 1930 showed the relationship between the gastrointestinal tract, brain, and skin. Probiotics have a role on acne vulgaris management due to its anti-inflammatory effect.
Riwayat Merokok sebagai Faktor Risiko Kematian Mendadak akibat Penyebab Kardiovaskular: Laporan Kasus Berbasis Bukti Kemal Akbar Suryoadji; Arfian Muzaki; Hanna Angelia Rahmatullah; Mutiara Intan Permata Sari; Oktavinda Safitry
Cermin Dunia Kedokteran Vol 50 No 7 (2023): Kardiovaskular
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i7.959

Abstract

Latar Belakang: Penyebab kematian mendadak yang utama adalah penyakit kardiovaskular yang dikenal sebagai kematian kardiak mendadak, di mana 80% disebabkan oleh penyakit jantung koroner. Salah satu faktor risiko penyakit jantung koroner adalah merokok. Menurut Riset Kesehatan Dasar (Riskesdas) 2018, prevalensi nasional perokok pada populasi usia >10 tahun sekitar 28,8%. Tinjauan ini akan menelusuri riwayat merokok sebagai faktor risiko kematian kardiak mendadak. Metode: Pencarian artikel dari 3 database, yaitu Pubmed, Cochrane, dan ScienceDirect dengan kata kunci “(Sudden Cardiac Death) AND (Smoking)”. Pencarian berdasarkan kriteria inklusi dan eksklusi serta telaah kritis sesuai panduan untuk studi etiologi. Hasil: Didapatkan 1 artikel systematic review yang memenuhi kriteria, yaitu studi Aune D, et al, (2018). Hasil studi tersebut yaitu pasien dewasa dengan riwayat merokok mempunyai risiko tiga kali lebih besar untuk mengalami kematian kardiak mendadak dibandingkan pasien tanpa riwayat merokok. Simpulan: Risiko kematian kardiak mendadak meningkat tiga kali pada pasien perokok aktif.   Background: The most common cause of death is cardiovascular disease, known as cardiac death; 80% of cardiac deaths were associated with coronary heart disease. One of the risk factors for coronary heart disease is smoking. According to the 2018 Basic Health Research (Riskesdas), the national prevalence of smokers at the age of >10 years is around 28.8%. This review will explore the association of smoking history as a risk factor for cardiac death. Methods: Search articles from 3 databases: Pubmed, Cochrane, and ScienceDirect with the keywords “(Sudden Cardiac Death) AND (Smoking)”. Search based on inclusion and exclusion criteria and critical review according to guidelines for etiological studies. Results: One systematic review article met the criteria, namely the study of Aune D, et al, (2018). Adult patients with a history of smoking have a 3x higher risk of cardiac death compared to patients without a history of smoking. Conclusion: The risk of sudden cardiac death increases three times in patients who are active smokers.
Sindrom Chorea Hiperglikemia Ganglia Basalis: Laporan Kasus Amelia Puspita; I Ketut Sumada; Ni Ketut Candra Wiratni; Desie Yuliani; Ni Made Kurnia Dwi Jayanthi
Cermin Dunia Kedokteran Vol 51 No 7 (2024): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i7.963

Abstract

Background: Chorea hyperglycemia basal ganglia (C-H-BG) syndrome is an uncommon manifestation of diabetes mellitus seen in patients with poor glycemic control. Case: A 74-year-old poorly controlled diabetic women with acute onset of movement disorder in the form of uncontrolled choreiform movements of her left upper and lower extremity. Her initial glucose level was 289 mg/dL and HbA1C was 9.5%. Discussion: Most C-H-BG patients are older Asian female. Female predisposition is probably related to the estrogen decline during menopause, resulting in gamma-aminobutyric acid (GABA) depletion or dopamine receptors hypersensitivity and enhancement of dopaminergic system. Its pathophysiology has not been entirely defined. Conclusion: C-H-BG is a rare manifestation of poorly controlled diabetes. Early recognition and treatment of elevated blood glucose levels appear to lead to total resolution.
Faktor Prediktif Rekurensi Dini Adenokarsinoma Pankreas Setelah Bedah Reseksi Kuratif: Systematic Review Muhammad Faza Soelaeman; Favian Ariiq Rahmat; Aji Wahyu Wardhana
Cermin Dunia Kedokteran Vol 51 No 6 (2024): Cardiology
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i6.965

Abstract

Introduction: Pancreatic adenocarcinoma stands as one of the most devastating forms of cancer, with a survival rate of less than 5% after 5 years. Despite resection surgery being the only curative option, recurrence occurs in up to 85% of cases. It is crucial to identify factors that can accurately predict the probability of recurrence for more effective management strategies. Method: Following the PRISMA guidelines, a systematic review was carried out by extracting relevant studies from the PubMed MEDLINE database. Results: A total of 1,345 studies were initially identified, and 34 studies were analyzed. A total of thirty-five predictive factors were identified and classified into preoperative and postoperative categories. These factors were be further subdivided into patient characteristics, biomarkers, tumor characteristics, and genetics. The most frequently observed factors were lymph node metastasis, serum CA 19-9 level, and tumor size. Conclusion: Preoperative and postoperative patient characteristics, genetics, biomarkers, and tumor characteristics data can be utilized to predict and implement suitable follow-up strategies aimed at enhancing patient survival rates.
Gambaran Kasus Osteomielitis Kronis di Rumah Sakit Tingkat II Kartika Husada Kabupaten Kubu Raya Provinsi Kalimantan Barat Periode Januari 2015 – Desember 2017 Cahayo Mahandro Mahandro; Ganda MRH Purba; Ery Hermawati
Cermin Dunia Kedokteran Vol 51 No 8 (2024): Penyakit Dalam
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i8.966

Abstract

Osteomyelitis is a bacterial infection in bone or bone marrow. This study was a retrospective descriptive study of chronic osteomyelitis cases at Kartika Husada Level II Army Hospital of Kubu Raya Regency from January 2015 to December 2017 as well as a description of its management. There were 47 subjects taken based on their medical records. Surgical management was done in 39 cases (83.0%), consisting of debridement and sequestrectomy (33 cases), debridement (4 cases), and amputation (2 cases). Surgical management was combined with non-surgical management.
Perilaku Seksual Lesbian, Gay, Biseksual,Transgender, dan Risikonya terhadap Infeksi Menular Seksual Monika Puspitasari; Devi Artami Susetiati; Agnes Sri Siswati
Cermin Dunia Kedokteran Vol 50 No 12 (2023): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i12.968

Abstract

Lesbian, gay, bisexual, transgender (LGBT) face many gaps in sexual health aspects, including an increased risk of human immunodeficiency virus (HIV infection), sexually transmitted infections (STIs), and pregnancy. LGBT often experience social stigmatization, isolation, and rejection, even from their respective parents. Risk of STIs is related to sexual orientation, sexual anatomy, and sexual behaviour. LGBTs sexual activity may vary and with multiple partners, who are vulnerable to transmission of STIs and HIV infection. Health care providers are responsible for an open discussion regarding sexual health issues; including sexual orientation, sexual behavior, and gender identity.
Efektivitas Citicoline sebagai Terapi Gangguan Kognitif pada Stroke Iskemik Akut Lothar Matheus Manson Vanende Silalahi; Pradita Sri Mitasari
Cermin Dunia Kedokteran Vol 51 No 2 (2024): Dermatologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i2.971

Abstract

Background: Cognitive impairment in acute ischemic stroke is associated with disability, poor functional outcome, and mortality, hence requires effective management. Citicoline is one of pharmacotherapy for central nervous system disorders. This study aims to evaluate current evidence of the effectiveness of citicoline for cognitive impairment in acute ischemic stroke. Methods: Systematic review and meta-analysis on randomized controlled trials searched in PubMed, Cochrane, and Google Scholar databases. Screening was done on 518 articles according to inclusion and exclusion criteria, 3 articles were qualified for review. Results: Cano-Cuenca, et al, (2015) found that citicoline was associated with a mini-mental state examination (MMSE) score of >25 at 12 weeks. Pinzon & Asanyi (2018) found that the use of citicoline can prevent cognitive impairment at 6 and 12 months, especially in attention and temporal orientation. Bonvicini, et al, (2022) found that citicoline is associated with good cognitive outcomes as measured with global cognitive impairment. Conclusion: Citicoline is effective as a therapy for cognitive impairment in acute ischemic stroke.
Potensi Citicoline sebagai Terapi Neuroproteksi dan Neuroregenerasi pada Stroke Iskemik Akut Zalfa Nihamuyassari Kanilla; Maryam Azizah; Fery Luvita Sari
Cermin Dunia Kedokteran Vol 51 No 3 (2024): Neurologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i3.974

Abstract

Ischemic stroke, caused by a blockage in the brain’s blood vessels, is a critical emergency that requires immediate treatment. This study examined the efficacy of citicoline as an adjunct therapy to improve outcomes in acute ischemic stroke. A comprehensive search of four databases (Cochrane Library, ScienceDirect, PubMed, and Google Scholar) was conducted, identifying a total of 5265 articles. Three clinical trials were selected for critical appraisal. Agarwal demonstrated a larger reduction in stroke infarct volume in the citicoline group (4.22 cm3) compared to the placebo group (2.63 cm3) (p=0.483). On day 90, the citicoline group exhibited superior results in mRS scores of 0-2 (p=0.732), NIHSS scores of 0-2 (p=0.934), Barthel index ≥95 (p=0.564), and patient mortality (p=0.468). Seifaddini’s study revealed improved peak systolic velocity and mean arterial flow velocity in the cerebrovascular system. Enrico’s study showed improved mean short afferent latency inhibition in the cholinergic circuits of the citicoline group (p=0.004). Citicoline proves effective as an adjuvant neuroprotective and neuroregenerative therapy for acute ischemic stroke.
Diagnosis dan Tata Laksana Dissociated Vertical Deviation Saphira Evani; Ni Made Ayu Surasmiati; I Wayan Eka Sutyawan
Cermin Dunia Kedokteran Vol 51 No 4 (2024): Oftalmologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i4.975

Abstract

Dissociated vertical deviation (DVD) is characterized by an upward deviation of one eye in the absence of any compensatory movement in the other eye. This condition is often seen in strabismus and can cause visual disturbances such as double vision and amblyopia. Its underlying causes are believed to be related to abnormalities of the visual pathways to control eye movements. Treatment options include observation, conservative management, and surgical intervention, depending on the severity and underlying cause. 
Peran Sucralfate Topikal dalam Mengurangi Nyeri Pasca-Hemoroidektomi Jessica Nathania; Shania Sutanto Jaya; Anthony Yauwono
Cermin Dunia Kedokteran Vol 51 No 5 (2024): Kedokteran Umum
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i5.976

Abstract

Hemorrhoids are one of the most common perianal cases and may cause lower gastrointestinal bleeding. Most cases can be treated with medications and/or simple procedures. Surgical intervention is required in advanced stages or complicated cases. However, this procedure is often associated with postoperative pain. Topical sucralfate is known to reduce postoperative pain.

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