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Samsul A Rahman Sidik Hasibuan
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Jurnal Kajian dan Inovasi Ilmu (JKII)
Published by Marasofi International Media and Publishing
ISSN : -     EISSN : 31093442     DOI : https://doi.org/10.64123
Core Subject : Humanities, Education, Social,
Humanities Education Languange, Linguistic, Communication & Media Social Sciences Other
Jurnal Kajian dan Inovasi Ilmu (JKII) bertujuan untuk mendorong diseminasi hasil pemikiran dan penelitian ilmiah lintas disiplin yang berorientasi pada inovasi dalam teori, metode, maupun aplikasi nyata. Fokus utama jurnal ini meliputi kajian konseptual, pendidikan, inovasi teknologi, kebijakan publik, hingga integrasi sains dan teknologi dalam pembangunan berkelanjutan.
Arjuna Subject : Ilmu Sosial - Ilmu Sosial (Lain-Lain)
Articles 12 Documents
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Peran Pemberdayaan UMKM Terhadap Ketahanan Ekonomi Lokal Perspektif Ekonomi Islam Nabila Nurbaya; Anggi Eka Davinata; Irsya Julia Noer Arista; Mashudi
Jurnal Kajian dan Inovasi Ilmu (JKII) Vol. 1 No. 2 (2025): November
Publisher : Marasofi International Media and Publishing (MIMP)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64123/jkii.v1.i2.1

Abstract

Usaha Mikro, Kecil, dan Menengah (UMKM) merupakan salah satu pilar penting dalam membangun ketahanan ekonomi lokal. Penelitian ini bertujuan untuk menganalisis peran pemberdayaan UMKM dalam memperkuat ketahanan ekonomi daerah melalui pendekatan ekonomi Islam. Hasil kajian menunjukkan bahwa pemberdayaan UMKM melalui pelatihan, pembiayaan syariah (seperti mudharabah dan qardhul hasan), serta pendampingan berbasis nilai-nilai syariah mampu meningkatkan kapasitas usaha, mendorong kemandirian ekonomi masyarakat, dan mengurangi ketimpangan. Selain itu, UMKM juga berperan dalam menciptakan lapangan kerja, mendukung pertumbuhan sektor riil, serta memperkuat daya saing lokal. Dalam perspektif ekonomi Islam, pemberdayaan UMKM menjadi sarana mencapai kemaslahatan dan keadilan ekonomi yang berkelanjutan. Oleh karena itu, sinergi antara program pemberdayaan dan prinsip-prinsip syariah sangat diperlukan untuk membangun ekonomi lokal yang tangguh, inklusif, dan bernilai ibadah.
Chemical Structure Profile and Computational Descriptors of Fenbufen Butanamine by PubChem Yuneka Saristiana; Fendy Prasetyawan; Ratna Mildawati; Yogi Bhakti Marhenta; Eka Hayati Rhomah; Mujtahid Bin Abd Kadir
Jurnal Kajian dan Inovasi Ilmu (JKII) Vol. 1 No. 2 (2025): November
Publisher : Marasofi International Media and Publishing (MIMP)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64123/jkii.v1.i2.2

Abstract

Fenbufen Butanamine is a structural derivative of the non-steroidal anti-inflammatory drug (NSAID) Fenbufen, characterized by the addition of a butanamine group to its core structure. This modification is intended to improve the pharmacokinetic and pharmacodynamic properties of the parent compound, potentially enhancing its therapeutic efficacy. In this study, we conducted a detailed computational analysis of Fenbufen Butanamine’s chemical structure and molecular descriptors using data retrieved from the PubChem database. The chemical identity was confirmed by its IUPAC name, InChI, InChIKey, and SMILES notation, which provide precise molecular characterization essential for database referencing and further computational modeling. Key computational descriptors, such as molecular weight, logP, topological polar surface area (TPSA), and the count of hydrogen bond donors and acceptors, were analyzed to assess drug-likeness and predict pharmacokinetic behavior. Our findings indicate that Fenbufen Butanamine possesses a biphenyl core that contributes to hydrophobic interactions, while the butanamine side chain introduces hydrophilic properties. This amphiphilic nature is likely to influence the compound’s solubility, membrane permeability, and binding affinity to biological targets. The computed descriptors suggest favorable properties for oral bioavailability and potential interactions within biological systems. These results serve as a foundational step for in silico drug design and optimization of Fenbufen derivatives. Further experimental and pharmacological studies are warranted to validate these computational predictions and explore the therapeutic potential of Fenbufen Butanamine. 

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