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Mochamad Nashrullah
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Kavling Banar, Pilang, Sidoarjo, Jawa Timur
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INDONESIA
Journal of Medical Genetics and Clinical Biology (JMGCB)
Published by Antis Publisher
ISSN : -     EISSN : 30321085     DOI : https://doi.org/10.61796/jmgcB
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing
Journal of Medical Genetics and Clinical Biology is a peer-reviewed forum for advances at the intersection of human genetics and clinical medicine. The journal welcomes original research, reviews, brief reports, and case reports that translate genomic discoveries into clinical utility—spanning diagnostic workflows, risk stratification, therapeutic decision-making, and implementation in real-world care. Areas of interest include Mendelian and complex disorders, cancer genetics, pharmacogenomics, biomarkers, clinical genomics (panel testing, WES/WGS), bioinformatics and data integration, as well as ethical and counseling considerations. By bridging molecular insights and bedside applications, the journal aims to support precision health and improve outcomes across diverse patient populations.
Arjuna Subject : Imunologi dan Mikrobiologi (semua kategori) - Imunologi dan Mikrobiologi (Lain-Lain)
Articles 372 Documents
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INDUCTION CALLUS OF MORINGA PLANT (MORINGA OLEIFERA) IN VITRO Abdul-Sadah, Zahraa Abbas trad; Ahmed, Rahma Abd Al gabar; Fadhel, Sarah Salam Talib; Ibrahim, Mohammed Allawi Abed; Jiyad, Nawras Saadoun Majbas
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 8 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i8.835

Abstract

This study aims to find an easy and efficient way to induce callus tissue of (Moringa oleifera) in vitro. The seeds were used as explant for cultivation in vitro, these parts were sterilized with sodium hypochlorite (Naocl) at concentrations (0.0, 0.5, 1.0, 2.0%) for a period of time (5,10 ,15, 20 minutes) and mercury chloride solution 0.06,0.07,0.08 0.1 mg/L) and for a period of time (2,3,4,5 minutes). Explant were planted in the medium (Murashige and Skoog (MS) in addition to different concentrations of plant growth regulators (BA, NAA), either individually or in combination. The results showed that the use of sodium hypochlorite solution (NaocL) with a concentration of 2% and a sterilization period of 20 minutes gave the highest sterilization rate of 100% without causing damage to the plant part. Also, the seeds produced callus after 48 days of culture on Ms medium containing the best combination of plant growth regulators (BA 4.0, NAA 0.5 mg/L)
MCDM APPLICATION FOR BACTERIA MEASUREMENT DEVICES Shaalan, Maryam Khalid; Abdulkhalik, Humam Abduljabbar; Amran, Naba Ndhm
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 8 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i8.836

Abstract

This study explores the innovative use of gas sensors to detect bacterial infections. The fundamental reliance of this technique is on monitoring fluctuations in the quantities of biogenic gases produced by bacteria during their growth. Through analysis, these sensors can accurately identify the kind and severity of a disease by detecting chemicals such as ammonia and hydrogen sulphide. Preliminary studies indicate that gas sensors provide a rapid and non-intrusive method for diagnosing bacterial infections. Additionally, they possess a notable level of sensitivity and precision. This technology improves clinical results and reduces the transmission of infections, enabling healthcare personnel to administer the appropriate medications promptly
ESCHERICHIA COLI BACTERIA AND THEIR RESISTANCE PATTERN TO ANTIBIOTICS IN THE MATERNITY AND CHILDREN’S HOSPITAL/BABYLON Mohammed, Jafar Saad Abdul Redha; Shaheed, Ali Hamza Mohammed; Ali, Ahmed Mohammed Abed; Mohammed , Ahmed Raad Abdul Redha; Yousef, Mohamed Waleed Ahmed
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 8 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i8.839

Abstract

This study focused on collecting urine samples from the midstream of urinary tract from patients with urinary tract infection (UTI). It was clear that E. coli isolates dominated the rest of the isolates due to their importance in causing urinary tract infection in women and men. To achieve this goal, 100 midstream urine samples were collected from patients suffering from urinary tract infection in Maternity and Children's Hospital/Babylon from men and women for the period from 11/11/2018 to 1/11/2019. These samples were cultured on eosin medium and solid MacConkey medium to confirm the diagnosis. The disk diffusion method was used to test the sensitivity of the isolates of this bacterium to a number of antibiotics (18 antibiotics) used as treatments. The most important results are summarized as follows: 1. Isolation and diagnosis of 72 isolates carrying the characteristics of E. coli bacteria, with infection predominance in women (60 cases) more than men (19 cases). All E. coli isolates are resistant to antibiotics that affect the cell wall
FEATURES OF THE COURSE OF TUBERCULOSIS OF THE RESPIRATORY SYSTEM IN PATIENTS OF DIFFERENT AGE GROUPS Turdibekov, Khusan Ibragimovich; Khusanovich, Ibragimov Sanjarbek ; Sakhobzhonovna, Zhurabaeva Gulira'no
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 8 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i8.840

Abstract

A comparative analysis of the results of examination of young and elderly patients with respiratory tuberculosis is presented. Statistical data on the forms of tuberculosis, clinical pictures, clinical and laboratory data among this category of patients were obtained. Tuberculosis in adolescents is more often detected during preventive examinations and contact examinations, and among adult youth — when seeking medical help. Unilateral limited processes without destruction or with small cavities, without isolation of mycobacterium tuberculosis, are more typical for adolescents. In adults, tuberculosis is more often accompanied by pulmonary symptoms, intoxication, and complications. It is recommended to take into account the established features when working with these age groups at the stage of the general treatment network for the timely active detection of tuberculosis patients
EVALUATING THE IMPACT OF ENDOCRINE-DISRUPTING CHEMICALS ON FERTILITY IN WILDLIFE: FROM AMPHIBIANS TO MAMMALS Kadhim, Sajjad Jawad; Sahib, Mohsin Abbas; Khlaif, Salam Mohammed; AL-Azzawi, Mustafa Kareem; Zubaidi, Nabaa Abbas
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 8 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i8.841

Abstract

Endocrine-disrupting chemicals are contaminants that interrelate with wildlife's endocrine systems, producing negative influences on reproductive health and growth. Industrial pollutants, medicines and pesticides are between the chemicals that have develop a main source of worry due to of their pervasiveness in the environment and capability to reason ecological damage. This study brings both present data on the effects of EDCs on reproductive health in a diversity of animal species, particularly birds, fish, frogs, and mammals. Amphibians, together their complex life cycles and pored skin are particularly susceptible to EDCs. In relation to studies, contact to chemicals such as atrazine able to damage sexual development, causing in slanted sex proportions and developmental irregularities. Fish, which are significant indicators of marine ecosystem health, exhibition changed sexual development and reproductive disappointments due to of EDCs like estrogenic compounds and PCBs. Birds are harmed via EDCs like DDT, which leading to reproductive failures and eggshell thinning, influencing general population health. Mammals, reaching from little rodents to enormous animals, developmental defects, display lower fertility and behavioral alterations in reply to EDC exposure. Such EDCs clearly and profoundly affect reproductive health via altering gene expression, blocking receptors and mimicking hormones. Studies provide wide-ranging insights for these pathways, while field investigations afford experimental evidence of the effects of EDCs. Bio-monitoring methods, like tissue analysis and health markers, are very important to determining exposure levels and results. Identifying the influence of EDCs on animal reproductive health is significant for conservation initiatives and emerging regulation. Effective regulations might contain limiting the usage of dangerous chemicals and establishing monitoring systems to checked EDC levels in environment and the animals. Conservation efforts must prioritize habitat management and refurbishment because offset the effects of EDCs and safeguard endangered species. This research confirms the requirement for ongoing research and work to address the issues presented via endocrine disruption in animal populations. The research will explore how toxic chemicals disturb nature reproduction via analyzing variations in mating habits, sexual development, and fertility. It will examine how these materials influence hormonal systems via inhibiting receptors and mimicking hormones. Additionally, the research will observe current legislation governing these chemicals, assess their effectiveness, and refer for greater animal protection.
THE ROLE OF RUSTS IN CORROSION AND CORROSION PROTECTION OF IRON AND STEEL Hussein, Lubna Basem Kazim Abdul; Mater, Anwar Abdalmajeed Abdullah; Clinic, Hanin Khaled Mohammed; Alanbar, Dhuha Mazin Fawzi Khalaf; Ali, Saja Muwafaq Freah
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 8 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i8.844

Abstract

The processes of atmospheric corrosion of iron and steel and the properties of corrosion products (rusts) are modeled based on a quantitative evaluation of the chemical reactions pertaining to corrosion to elucidate the conditions with which corrosion-protective rust films form. in the initial stage of corrosion, in the rusts, the pH of the aquatic system is maintained at 9.31 owing to an equilibrium with iron (II) hydroxide and the rate of air-oxidation at this pH is very fast, and that dense, self-repairing rust films form, protecting the underlying iron and steel. However, after corrosion stops, the rust film deteriorates due to the dissolution and shrinkage by aging, and the deteriorated rust film separates the anode and cathode reaction products (Fe2+ and OH- ions) to cause crevice corrosion. The air-oxidation of iron (II) in anode channels without the presence of OH- ions results in strongly acidic solutions (pH 1.41), causing acid-corrosion. It is proposed that good catalysts (e.g. copper (II) and phos-phate ions) accelerate the air-oxidation at low pH, delaying the crevice- and acid-corrosion stages. Further, it is argued that iron compounds with negative charges due to the non- stoichiometric proportions of the lattice oxide ions and metal ions (solid oxoanions of iron) exhibit stable cation-selective permeability even with a drop in pH. Rust films including such compounds would stop the passage of aggressive anions and act to protect iron and steel.
PSYCHOLOGICAL TREATMENT APPROACHES FOR OBSESSIVE-COMPULSIVE DISORDERS DURING THE COVID-19 PANDEMIC Yunuskhodjaeva, Khilolakhon; Ibodullayev, Zarifboy; Maxamatjanova, Nodira
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 8 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i8.845

Abstract

This study investigates the psychocorrection of obsessive-compulsive disorders (OCD) exacerbated by the COVID-19 pandemic. The research involved a cohort of 40 patients diagnosed with OCD, whose symptoms intensified during the pandemic. Participants underwent a series of psychocorrective interventions, including cognitive-behavioral therapy (CBT), exposure and response prevention (ERP), and mindfulness-based techniques. The efficacy of these interventions was assessed through pre- and post-treatment evaluations using standardized OCD symptom scales and patient self-reports. Results indicated significant improvements in OCD symptoms and overall mental well-being. Patients reported reduced anxiety and compulsive behaviors, and increased ability to manage obsessive thoughts. The findings suggest that targeted psychocorrective strategies can be effective in alleviating pandemic-induced exacerbations of OCD, highlighting the importance of adapting therapeutic approaches to current global health crises
PRP THERAPY SIGNIFICANTLY REDUCES URINARY INCONTINENCE SEVERITY AND IMPROVES QUALITY OF LIFE Muzafarovna, Mukhammadzhonova Mohidil
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 8 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i8.846

Abstract

This study explores the efficacy of Platelet-Rich Plasma (PRP) therapy in treating urinary incontinence (UI) among women in Samarkand, Uzbekistan. Despite existing treatments, UI remains a significant concern, and PRP therapy's regenerative potential offers a promising alternative. Addressing a knowledge gap in long-term efficacy and quality of life impacts, a mixed-methods approach was employed, assessing 120 participants using ICIQ-SF, UDI-6, and SF-36 scores. Results indicated significant improvements in UI severity and overall quality of life, suggesting that PRP therapy could be a valuable, minimally invasive treatment. Further research is needed to optimize protocols and assess long-term outcomes
STRATEGY FOR THE INDUSTRIALIZATION OF DAIRY CATTLE BREEDING IN DEVELOPING COUNTRIES Bekzod, Djurayev; Chori , Kulmatov; Shukhrat, Nematjanov
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 8 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i8.847

Abstract

The industrialization of livestock products, including dairy farming, is one of the important issues in the context of population growth and global climate change. Also, a number of problems, such as meeting the population's demand for quality food and ensuring food safety, require the application of scientific achievements to the sector and increase investment attractiveness. Milk production in our republic poses a difficult question of introducing industrial technologies to animal husbandry while fully meeting the demands of the domestic market. If we take into account that 85% of the milk produced in our republic is produced by farmers' farms, we can understand that the intensification of the dairy sector is significantly complicated. At the same time, it is possible to reduce the cost of products and rational use of resources by improving the activity of livestock farmers.
OSTEOARTHRITIS - RISE OF AN UNRECOGNIZED EPIDEMIC Pradhan, Anmol Basudev
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 8 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i8.853

Abstract

Osteoarthritis (OA) is a degenerative joint disease characterized by the breakdown of cartilage, leading to pain, stiffness, and reduced mobility. Despite being the most common form of arthritis, OA is often underrecognized and undertreated. This article explores the rise of OA, its prevalence in developed versus developing nations, and the multifaceted factors contributing to its increasing incidence. We delve into the relationship between OA and nutritional factors, the impact of genetically modified foods and pesticides, and advancements in treatment options. By examining the latest research, we aim to highlight the need for greater awareness and more effective management strategies for this growing public health concern

Page 19 of 38 | Total Record : 372

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