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INDONESIA
Jurnal Kedokteran Brawijaya
Published by Universitas Brawijaya
ISSN : 02169347     EISSN : 23380772     DOI : http://dx.doi.org/10.21776/ub.jkb
Core Subject : Health,
Medicine & Pharmacology
JKB contains articles from research that focus on basic medicine, clinical medicine, epidemiology, and preventive medicine (social medicine).
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 10 Documents
 1 
Search results for , issue "Vol 20, No 2 (2004)" : 10 Documents clear
RISIKO KENAIKAN HEMATOKRIT TERHADAP TERJADINYA RENJATAN PADA KASUS DEMAM BERDARAH DENGUE Sumakto, Sumakto; Santoso, Nurtjahjo Budi; Nugroho, Susanto; Kawurjan, Siti Lintang
Jurnal Kedokteran Brawijaya Vol 20, No 2 (2004)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (100.827 KB) | DOI: 10.21776/ub.jkb.2004.020.02.2

Abstract

ABSTRACT Shock is life threatening feature of DHF it must be manage properly through close clinical and laboratory observations. This was a pre-eliminary study to evaluate hematocrit (Hct) increased where shock occurs on dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). The WHO criteria was used to diagnose DHF, with two or more clinical criteria with trombocytopenia (≤ 100.000) and Hct increase ≥ 20 %. Examination of hemoglobin (Hb), Hct, thrombocytes and leucocytes were done in RSU Dr. Saiful Anwar Central Laboratory everyday during hospitalized. The increase of Hct percentage and Hct/Hb ratio calculation were based on the result of lowest dan highest Hct and Hb examination. The data obtains was analysed with t-test using SPSS version 10.0 programme. From 30 DHF cases, 23 (76.66%) non DSS and 7 (23.77%) DSS. The average Hct increase in all patients from serial examinations was 21.09% (SD= 2.32%). However, in 7 DSS patients the average Hct increase was 23.79% (SD= 3.84%) higher than the 23 non DSS patients (20.28%; SD= 0.25%). It was observed that the Hct increase in DSS patients was higher than that for non DSS patients. This high Hct level of 23.79% increases the likelihood of shock by 2.5 times compare with an Hct rise of 20.28%. There was a significant difference in the highest and lowest Hct/Hb ratio between DSS and non DSS cases (p= 0.000). Keywords : dengue hemorrhagic fever, dengue shock syndrome, hematocrit increase, Hct/Hb ratio
PENGARUH PEMBERIAN TEMULAWAK PADA LAMBUNG TIKUS YANG MENGALAMI ULKUS PEPTIKUM AKIBAT INDUKSI INDOMETASIN Indraswari, Cokorde Istri; Kalsum, Umi; Sudjari, Sudjari
Jurnal Kedokteran Brawijaya Vol 20, No 2 (2004)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (145.218 KB) | DOI: 10.21776/ub.jkb.2004.020.02.8

Abstract

ABSTRACT The flavonoid content of Curcuma xanthorriza has an anti inflamatory effect. Inflamation is the basic mechanism in the occurrence of indomethacine induced peptic ulcer. The purpose of this research was detect the effect of the administration of Curcuma xanthorriza decoction in reducing the occurrence of indomethacine induced peptic ulcer. The research methodology used post test control group design. Randomly selected sample of 20 male wistar rat were classified into four groups. Group I (positive control, received 30 mg/kg bodyweight indomethacine), group II (dosage 1, received 30 mg/kg bodyweight indomethacine and 1,3 g/kg bodyweight Curcuma xanthorriza  decoction),  group  III  (dosage  2,  received  30  mg/kg  bodyweight  indomethacine  and  2,6  g/kg  bodyweight  Curcuma xanthorriza decoction), and group IV (dosage 3, received 30 mg/kg bodyweight indomethacine and 5,2 g/kg bodyweight Curcuma xanthorriza  decoction).  Indomethacine  and  Curcuma  xanthorriza  was  given  by  intragastric  administration.  The  parameter  to  be measured was the number of macroscopic gastric hemorrage lesion, because gastric hemorrage is the early manifestation of peptic ulcer. The result of this research was there is a significant difference in the number of macroscopic gastric hemorrage lesion between group I and the other three group (F test, p<0,05), and there is no significant difference for those of group II, III, and IV (F test, p>0,05). Conclusion: Curcuma xanthorriza can reduce the occurrence of peptic ulcer. Key words: Indomethacine, Curcuma xanthorriza, Peptic ulcer, Gastric hemorrage lesion
GAMBARAN KLINIS DAN LABORATORIUM SINDROM SYOK DENGUE RAWAT PICU RSU DR. SAIFUL ANWAR MALANG Budhy, Setya; YS, Mardhani; Muid, Masdar
Jurnal Kedokteran Brawijaya Vol 20, No 2 (2004)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (124.301 KB) | DOI: 10.21776/ub.jkb.2004.020.02.3

Abstract

ABSTRACT Dengue shock syndrome (DSS) is a clinical emergency case with still high mortality rate. During five years period (1January 1997?31 December 2001) total case of SSD triaded in PICU room Medical Faculty Brawijaya University/ Saiful Anwar Hospital Malang were thirty two patients. They were referred from Malang regency 9 patients (28%), Malang city 23 patients (72%). The most group age 6 ? 10 years 14 patients (44%), < 5 years 13 patients (41%), 11 ? 14 years 5 patients (15%). SSD is devided in DBD grade III 14 patients (44%), DBD grade IV 18 patients (56%). Laboratory finding total leucocyt count < 4000/mm3 8 patients (25%),  4000 ? 10000/mm3 24 patients (75%). Total thrombocyt < 50000 / mm3 22 patients (69%), 50000 ? 100000/ mm3 10 patients (31%). Hematocrit > 42% all patients (100%). Clinical sign found in SSD patients quickly and fine pulse 14 patients (44%), cold extremities 32 patients (100%), pulse not palpable 18 patients (56%). Blood tension : unmeasured 18 patients (56%), hypotension 18 patients (56%). Death patients 13 (41%) recovery patients 19 (59%). All SSD patients  (100%)  were death by complication of occult bleeding, pulmonary edema, respiratory failure.
EVALUASI HASIL PELATIHAN DAN PENDIDIKAN UNTUK PENANGANAN PRA RUMAH SAKIT TERHADAP PENDERITA CEDERA Soemarko, M.
Jurnal Kedokteran Brawijaya Vol 20, No 2 (2004)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (113.202 KB) | DOI: 10.21776/ub.jkb.2004.020.02.9

Abstract

ABSTRACT The  purpose  of  organized  trauma  system  management  of  pre  hospital  care  of  seriously  injured  patients  is  to  ensure  the  early intervention and transfer savely the patients to the best equipped facility to care of their injuries. The aims this research is to evaluate the results and the effectiveness of the training and education of pre hospital management in Saiful Anwar Hospital.  The method this research are an observational study of injured traffic accident patients preHospital care in Saiful Anwar General Hospital Malang. Training and education have been done intensively and continuously after August 1999 until now. The comparation was between 1st April until 31st Juli 1999 and 1st April until 31st Juli 200. The result of this research, a significant progress in pre hospital treatment, ambulance transportation and communication between field attendance and the trauma center. But significantless of progression in pre hospital medical records. Only reveral system from health center was significant developed. The intensive training and education of pre hospital management to the injured patient had a significant good results. The training and education must be continued and developed for a better results in the future.  Key words : Injured patients, pre hospital care, training and education.
HUBUNGAN ANTARA DERAJAT OBSTRUKSI SERANGAN AKUT ASMA DENGAN KADAR IgE, IFN- DAN IL-4 TOTAL SERUM Kusuma, HMS. Chandra; Kalim, Kusworini Handono; Riawan, Wibi; Muid, Masdar
Jurnal Kedokteran Brawijaya Vol 20, No 2 (2004)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (119.883 KB) | DOI: 10.21776/ub.jkb.2004.020.02.4

Abstract

ABSTRACT Acute bronchial asthma is a common medical emergency the world over. There now exists compelling evidence of a role for Th2-Th1 paradigm in the pathogenesis of asthma in children. We hypothesized that childhood asthma is associated with the activation of  Th2-Th1 lymphocytes whose products regulate at least in part, the expression of IgE, IFN-γ and IL-4 and thereby disease severity. Our aims, therefore were to compare the level of total IgE, total IL-4 and total IFN-γ in serum from asthmatic and non asthmatic control children matched for age and sex, and to attempt to correlate the IgE, IL-4, and IFN-γ total level of serum in the asthmatics children with disease severity. Fifty one children with acute asthma exacerbation were compare with thirty one no asthmatics normal children matched for age and sex. The level of IgE, IL-4, and IFN-γ were measured using Elisa. Asthma severity was assessed by a symptom score and spirometri. The level of IgE and Il-4 in the serum of the asthma were elevated as compared to the non asthmatic normal controls, whereas the IFN-γ was decreased. There was a significant correlation between elevated levels of IgE and IL-4 with the acute asthma exacerbation severity, whereas the decreased level of IFN-γ was not. Conclusions. The increased levels of IgE , IL-4 and the ratio of  IL-4/IFN-γ play a crucial role in the acute asthma exacerbation severity.
AKTIVITAS HEMAGLUTINASI BAKTERI ACINETOBACTER BAUMANNII YANG BERASAL DARI SPESIMEN KLINIK DAN LINGKUNGAN Noorhamdani, Noorhamdani
Jurnal Kedokteran Brawijaya Vol 20, No 2 (2004)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (835.65 KB) | DOI: 10.21776/ub.jkb.2004.020.02.10

Abstract

ABSTRACT Acinetobacter baumannii (Acb) is an opportunistic or a nosocomial pathogenic bacterium which attacks immunocompromised host. Colonization and infection often occur while hospitalized and could lead to pneumonia infection, urinary tract infection, meningitis, septicemia, and burn or surgical wound infections. In spite of the steady increase of Acb infection cases, little has been revealed about the Acb infection mechanism. The infection process is initiated by the adhesion of bacteria onto the host’s cell, followed by multiplication, colonization and infection. Adhesion onto the host’s cell is mediated by the adhesin molecule functioning as the virulence factor. Adhesin is usually found in the form of hemaglutinin protein which is bound to the receptor available at the host’s cell surface. Target of research is to know weather the bacterium have hemaglutinin protein, by seeing the ability of agglutination red blood of mice 0.5%. Isolate of Acb coming from clinical specimen consisted of urine 35 isolates, sputum 27 isolates, pus 15 isolates, and blood 1 isolat.
DIARE ROTAVIRUS PADA ANAK DIBAWAH USIA 3 TAHUN YANG DIRAWAT DI RSU DR. SAIFUL ANWAR MALANG TAHUN 2005 (PRELIMINARY STUDY) Santoso, Nurtjahjo Budi; Hamid, Aulia Abdul; Santoso, Sanarto
Jurnal Kedokteran Brawijaya Vol 20, No 2 (2004)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (97.132 KB) | DOI: 10.21776/ub.jkb.2004.020.02.5

Abstract

ABSTRACT Rotavirus is the most common cause of acute diarrhea among children worldwide. The majority of the cases required hospitalization. Epidemiologic pattern and clinical manifestation could be helpful in establishing the proper diagnosis and management. To find out prevalence and the clinical pictures of rotavirus diarrhea among children under three years of ages with acute diarrhea admitted in the Department of Child Health Dr. Saiful Anwar General Hospital. The stools of children under three years of age with acute diarrhea between March 1st and May 1st, 2005 were assessed for rotavirus using Latex agglutination test (Slidex, Rota K2, bio Merieux). Age, sex, clinical sign and symptoms and breast-fed were recorded. The severity of acute diarrhea was estimated using WHO criteria. Statistical analysis were performed using EpiInfo 2000 program with x2 or x2 for trend. From the 40 patients with acute diarrhea were found 16 patients (40%) with rotavirus positive, both male and female were 8 patients (50%). Distribution of rotavirus positive patients in age group were 0-5 months 3/16 (18,7%), 6-11 months 6/16 (37,5%), 12-23 months 6/16 (37,5%) and 24-36 months 1/16 (6,3%). Clinical manifestations showed that most children had fever (75%), vomiting (87.5%) and dehydration (87.5%). Rotavirus infection among breast-fed patients were found less than bottle-fed patients.
PENGARUH KADAR TROMBOSIT, HEMATOKRIT, HEMOGLOBIN DARAH DAN PROTEIN URIN PADA IBU PREEKLAMSI /EKLAMSI TERHADAP NILAI APGAR BAYI YANG DILAHIRKAN Kawuryan, Siti Lintang
Jurnal Kedokteran Brawijaya Vol 20, No 2 (2004)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (111.214 KB) | DOI: 10.21776/ub.jkb.2004.020.02.6

Abstract

ABSTRACT Preclapmsi or eclampsia is one of the risk factor for asfiksia on newborn that can predicted by lower Apgar score. The aim of this research  is  to  know  the  influence  of  the  trombocyte,  hematokrit,  hemoglobin,  and  urinary  protein  examination  of  preclampsi  or eclampsi mother to baby’s Apgar score. This research was a diskriptive-cross sectional retrospective study with Chi- square test, Fisher test x2 for trend statistic analysis. Total sample was 100 which choosen by simple random sampling. The parameter of this study was trombocyte, hematokrit, hemoglobin, and urinary protein examination of preclampsi or eclampsi mother and baby’s Apgar score. There was a significant influence relationship between the raise of blood hematocrit (p=0,0243), the decrease of the blood trombocyte (p= 0,0175) and the high level of proteinuria (p=0,0154) of preclampsi or eclampsi mother  to baby’s Apgar score. In the other hand, hemoglobin (p =0,3589), SGOT (p=0,5447),SGPT (p= 0,4850), Ureum (p = 0,1964), kreatinin (p= 0,3415) level was not significantly influence. The conclusion of this reseach is hematokrit ≥ 38 % and urinary protein ≥ 4+ on preclampsi or eclampsi mother are usefull for predicting lower Apgar score of the neonate with relative risk 7,609. Keyword: preclampsi or eclampsi, trombocyte, hematokrit, hemoglobin, and urinary protein examination, Agar score
POLA DAN SENSITIVITAS TERHADAP ANTIBIOTIK BAKTERI PENYEBAB INFEKSi SALURAN KEMIH ANAK DI RSU DR SAIFUL ANWAR, MALANG Subandiyah, Krisni
Jurnal Kedokteran Brawijaya Vol 20, No 2 (2004)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (161.845 KB) | DOI: 10.21776/ub.jkb.2004.020.02.1

Abstract

ABSTRACT Urinary tract infection (UTI) is one of the most common bacterial infections affecting children. Early recognition and prompt treatment of UTIs are important to prevent progression of infections and to avoid late sequeale. The aim of the study was to identify the bacterial agents of urinary tract infections in children and to study sensitivity to antibiotics. Urinary specimens were collected from children suffering from urinary tract infections, who were either inpatients or outpatients between January 1999 and December 2003. Of a total of 563 urine specimens, bacteriuria was found in 276 (49.02%) of patients. Females showed a higher prevalence of infection (51.1%) than  males  (48.9%).  Mean  age  was  63  months,  median age  was  60  months  (range  1  month  to  12  years).  The microorganisms isolated  from  children  included  Escherichia  coli  (48.9%),  Acinetobacter  anitratus  (9.8%),  Klebsiella  pneumoniae  (9.4%), Staphylococcus positive coagulase (5.8%), Proteus mirabilis (4.7%), others (21.4%). Escherichia coli was sensitive to nitrofurantoin (74.8%),  nalidixic  acid  (69.6%),  cefotaksim  (48.9%),  Amoxcillin  clavulanat  acid  (37.8%),  fosfomicin  (35.6%),  gentamicin  (34.1%), ceftriaxone (31.8%), amikacin (19.2%), cotrimoxazole (15.6%), ciprofloxacin (11.1%), cefuroxim (3.7%), netilmicin (8.9%), amoxcilin (2.9%),  chloramphenicol  (2.2%),  ampicilin  (2.2%).  Resistant  to  ampicillin  dan  chloramphenicol  97.8%.  Acinetobacter  anitratus sensitive to nalidixic acid (62.96%), Amoxcillin clavulanat acid (48.15%), gentamicin (40.74%), co-trimoxazole (33.33%), nitrofurantoin (25.93%), amoxcilin (25.93%), amikacin (11.11%), netilmycine (11.11%), ampicillin (7.40%), ciprofloxacin (7.40%), cefotaxim (7.4%), ceftriaxon (7.4%), cefuroxim (3.7%).
PENATALAKSANAAN SINDROMA MAYER ROKITANSKY KUSTER HAUSER (SINDROMA MRKH) DENGAN SINDROMA KLIPPEL FEIL Wiyasa IW, Arsana; Mukminah, Aisyatul
Jurnal Kedokteran Brawijaya Vol 20, No 2 (2004)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (106.457 KB) | DOI: 10.21776/ub.jkb.2004.020.02.7

Abstract

ABSTRACT It was reported that a 19 year old woman, suffered from Muller duct agenesis. The patient came to RSSA, complained about primary amenorrhea and assimetrical of head position. Tuba, uterus and 2/3 proximal vagina were not formed. Both of ovaries seemed normal. Based on vaginal sondage, the vagina canal is only 1.5 cm. Secondary sexual characteristics developed normally. By skull and cervical X – ray, it was found fusion of vertebrae cervical 3, 4. The vagina and the uterus are not present, but the tuba and the ovarium are normal; this case is known as Mayer Rokitansky Kuster Hauser Syndrome. Moreover, it is accompanied by another congenital defect, i.e. fusion of vertebrae cervical 3 and 4, which is called Klippel Feil Syndrome. In the exploration, it was found that there was a constitution of cromosom 46,XX. It has been done hormonal examination: FSH, LH, estrogen, prolactin and was obtained testosteron < 127.8 ng/dl. The patient was grews up as a woman. Her behavior, attitude, emotion and sexual behavior are likely a woman.  We plan to perform and suggest her to adopts a child. To treat the Klippel Feil, it is important prevention of the neck trauma and complication of neurology and arthritis. Key word : Mayer Rokitansky Kuster Hauster Syndrome, Klippel Feil Syndrome, vaginoplasty

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