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Jl. Buaran 2 No.30 A, RT.10/RW.13, Klender, Kec. Duren Sawit, Kota Jakarta Timur, Daerah Khusus Ibukota Jakarta 13470
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Jurnal Farmasi Ikifa
Published by Sekolah Tinggi Ilmu Kesehatan IKIFA
ISSN : 2808702X     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology Public Health
Jurnal Farmasi IKIFA adalah forum untuk publikasi karya berkualitas dan orisinal yang membuka diskusi dalam bidang farmasi atau sub-disiplin ilmu lainnya.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 119 Documents
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IDENTIFIKASI KANDUNGAN FORMALIN PADA KUE YANG BEREDAR DI PASAR TRADISIONAL PERUMNAS KLENDER JAKARTA TIMUR Tria Prayoga; Pricillya Maria Loimalitna; Ivan Santoso; Asfiati Asysyifaa
Jurnal Farmasi IKIFA Vol. 2 No. 1 (2023): JURNAL FARMASI IKIFA VOL.2 NO.1 TAHUN 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Abstract

Based on BPOM, in Indonesia there are around 20 million cases of food poisoning per year. Palembang's BPOM agency also found market snacks, kue apem cakes and a number of other foods to contain formalin. BTP (Food Additives) which are often used in food processing are preservatives such as formalin. Formalin is used because it can extend the shelf life of the food. This study aims to test the alleged presence of formaldehyde in samples of wet cakes circulating in Klender Market, East Jakarta. The method used in this study is the identification of formalin compounds by qualitative chemical analysis using Schiff's reagent. In this study, it was found that samples of apem cakes, cucur cakes and putu ayu cakes from the Perumnas Klender Traditional Market, East Jakarta, did not contain formalin compounds.
GAMBARAN KESESUAIAN RESEP RAWAT JALAN JKN TERHADAP FORMULARIUM NASIONAL DI POLIKLINIK RUMAH SAKIT KARTIKA HUSADA JATIASIH Rahmat Widiyanto; Alifa Sabrina; Viquardo Wollyano Xezandrio
Jurnal Farmasi IKIFA Vol. 2 No. 1 (2023): JURNAL FARMASI IKIFA VOL.2 NO.1 TAHUN 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Abstract

In order to meet the basic needs of a good life for the people of Indonesia, the government established the National Social Security System. The Social Security Organizing Agency (BPJS) is an institution formed to organize social security assistance programs in Indonesia. The program is referred to as the National Health Insurance (JKN) program. The National Formulary is a list of selected medicines needed and available in health service facilities as a reference in the implementation of the National Health Insurance (JKN). The benefits of the national formulary for quality control and optimizing services to patients. This research aims to determine the percentage of suitability of JKN outpatient prescriptions to the National Formulary at the Kartika Husada Jatiasih Hospital polyclinic for the January – March 2022 period based on prescription sheets, medicine items for each prescription sheet, and prescribing generic and non-generic medicine. This research is descriptive, which explains how the suitability of the polyclinic JKN outpatient prescription to the National Formulary. The population in this research was all JKN outpatient prescription sheets written by doctors at the polyclinic in January as many as 851 sheets, February as many as 610 sheets, and March as many as 796 prescription sheets. The sampling technique uses total sampling. The results showed that the total percentage of suitability for the January – March 2022 period based on prescription sheets was 53.97%, based on medicine items of 79.74%, and prescribing generic and non-generic medicines of 75.33% generic and non-generic at 24.67%.
MONITORING KADAR GULA DARAH PADA PASIEN DIABETES MELITUS TIPE 2 DENGAN HIPERTENSI DI PUSKESMAS TLOGOSARI KULON KOTA SEMARANG Fef Rukminingsih
Jurnal Farmasi IKIFA Vol. 2 No. 2 (2023): JURNAL FARMASI IKIFA VOL.2 NO.2 OKTOBER TAHUN 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Abstract

Type 2 diabetes mellitus (T2DM) is a metabolic disease characterized by hyperglycemia. T2DM is a risk factor for hypertension. T2DM patients with hypertension who have uncontrolled blood glucose levels can cause more serious complications. This study aims to determine blood sugar levels in T2DM patients with hypertension at the Tlogosari Kulon Health Center, Semarang City. This research is a descriptive observational study. Data collection uses purposive sampling technique. The data used is medical record data of T2DM patients with hypertension at the Tlogosari Kulon Health Center, Semarang City for the period September 2022 - February 2023. The inclusion criteria for this study are patients who are ≥ 45 years old, have the results of checking fasting blood sugar levels (FBSL) for 2 consecutive months. Incomplete data will be excluded. The results showed that of the 40 T2DM patients with hypertension, there were 26 female patients and 14 male patients. Most patients were aged 60-69 years, namely 22 people. A total of 30 patients used oral hypoglycemic drugs for less than 5 years. A total of 31 patients (77.5%) received combination therapy with metformin and glimepiride. A total of 12 patients (30%) had fasting blood sugar levels in accordance with the therapy target.
Formulasi Tablet Kunyah Asetosal Dengan Variasi Konsentrasi Gelatin Sebagai Bahan Pengikat Terhadap Uji Fisik Tablet Kinanthi Dwi Utami; Rani Prabandari; Sunarti
Jurnal Farmasi IKIFA Vol. 2 No. 2 (2023): JURNAL FARMASI IKIFA VOL.2 NO.2 OKTOBER TAHUN 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Abstract

Acetosal, a nonsteroidal anti-inflammatory drug that is included in the category of drugs with a dose of 80 mg. In patients with coronary heart disease and severe hypertension, this drug is used as antiplatelet therapy with the aim of preventing stroke. Acetosals are included in the BCS class II category, so efforts are needed to develop formulations that can increase the speed of dissolution and provide a fast effect. This study aims to determine the variation in gelatin concentration as a binding agent to physical properties and determine the best gelatin concentration that meets the dissolution test of acetosal chewable tablets. The method used to make acetosal chewable tablets is direct felt. Acetosal chewable tablets are made into 3 formulas with variations in the concentration of gelatin binders of 2%, 6%, and 10%. The data obtained is then analyzed with one-way ANOVA. The results showed variations in gelatin concentrations of 2%, 6%, and 10% resulting in good physical properties of acetosal chewable tablets. The gelatin concentration of 2% in formula 1 showed the best results with an average test value of uniformity of weight 220.6 ± 1.42 mg, uniformity of diameter size 0.838 ± 0.01 cm, and thickness 0.436 ± 0.01 cm, hardness 4.3 ±0.15 kg, brittleness 0.49 ± 0.32%, crushing time 31 ± 3.0 seconds and dissolution 95.81%. A significant difference in values was found in the hardness test results (p = 0.001) and the time of destruction (p = 0.000). The best percent dissolution is found in Formula 1 with a dissolution value of 95.81%.
EVALUASI PENGGUNAAN OBAT ANTIHIPERTENSI PADA PASIEN HIPERTENSI DI INSTALASI RAWAT JALAN RUMAH SAKIT UMUM BHAKTI ASIH CILEDUG PERIODE OKTOBER-DESEMBER 2021 Suny Koswara Suny
Jurnal Farmasi IKIFA Vol. 2 No. 2 (2023): JURNAL FARMASI IKIFA VOL.2 NO.2 OKTOBER TAHUN 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Abstract

Hypertension is an increase in systolic blood pressure exceeding 140 mmHg and diastolic blood pressure exceeding 90 mmHg in two measurements with an interval of five minutes in a state of sufficient rest or calm (Kemenkes, 2019). The purpose of this study was to determine the rationale for the use of antihypertensive drugs in hypertensive patients at the Outpatient Installation of Bhakti Asih General Hospital, Ciledug, October-December 2021. This study used a descriptive design with retrospective data collection. The data used in this study were medical record sheets of hypertension patients at Bhakti Asih General Hospital Ciledug for the period October-December 2021 with a Cross Sectional approach. This study used a simple random sampling technique and obtained 165 patients who met the inclusion criteria. Based on the results of the study, it is known that the characteristics of adult hypertensive patients based on age are the most elderly age >60 years, namely 95 patients (57.57%) and based on gender the most are women as many as 103 patients (62.42%). The most used class of drugs was the CCB group 69 patients (41.81%), the antihypertensive group that the single therapy was mostly used was 103 patients (66.43%), and the group of combination drugs used was the CCB+ARB group 48 patients ( 29.09%). Evaluation of rational drug prescribing on each criterion, namely 100% Right Patient, 100% Right Indication, 100% Right Drug, 97.58% Right Dose.
UJI AKTIVITAS ANTIINFLAMASI EKSTRAK METANOL, ETIL ASETAT DAN N-HEKSANA DAUN LAMUN (Enhalus Acoroides) PADA TIKUS GALUR WISTAR DENGAN INDUKSI KARAGENAN Fatimah Munawaroh; Rani Prabandari; Galih Samodra; Adita Silvia Fitriana
Jurnal Farmasi IKIFA Vol. 2 No. 2 (2023): JURNAL FARMASI IKIFA VOL.2 NO.2 OKTOBER TAHUN 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Abstract

Inflammation is a response to damage to the tissue and infections that occur in the body's cells. Seagzador leaves Enhalus acoroides) contain secondary metabolites that are thought to have the potential as an anti -inflammatory agent. This study has the aim to understand the effect of the type of solvent on methanol extract, ethyl acetate and n-hexane seagrass leaf (Enhalus acoroides) on the foot edema of the wistar strain mice that is induced by carrageenan and know the value of AUC and %Dai. Anti -inflammatory testing is done by creating artificial edema in the foot of mice through 1%induction of carrageenan. The treatment is given to the test animals with the provisions: Group 1 is used as a negative control by administering 0.5%CMC Na, group 2 acts as a positive control that receives Na Diclofenac while groups 3, 4, and 5 are given methanol extract, ethyl acetate extracts, and N-hexane extract from Enhalus acoroides leaves dose 875 mg/kgBB. From the results of the study it is known that methanol solvents are more effective in inhibiting inflammation compared to extracts originating from ethyl acetate and n-hexane with an AUC value of 0.019 and %DAI of 39.834 %. Keywords: Anti-inflammatory, Enhalus acoroides leaves, %DAI
FORMULASI MASKER GEL PEEL OFF EKSTRAK DAUN SIRSAK (Annona muricata L.) SEBAGAI ANTI JERAWAT Junaedi; Yetri Elisya; Yusmaniar1; Tiara Insyirah Wijaya
Jurnal Farmasi IKIFA Vol. 2 No. 2 (2023): JURNAL FARMASI IKIFA VOL.2 NO.2 OKTOBER TAHUN 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Abstract

Acne is an inflammation of the skin due to increased production of sebum, keratinocytes, and the growth of Propionibacterium Acne bacteria so that pores are clogged. Soursop leaves (Annona Muricata L.) have a secondary metabolite that functions as an antibacterial, namely flavonoids. This study aims to determine the formulation of a peel-off gel mask from soursop leaf extract (Annona Muricata L.) which has the best characteristics. The physical evaluation includes organoleptic, pH, viscosity, dispersal power, adhesion, drying time, and stability test for 12 days of storage at temperatures of 4ºC and 40ºC. Research using experimental methods. Soursop leaf extract was extracted using percolation. The study was conducted using a peel-off gel mask preparation using concentration differences of 5%, 10%, and 15%. Based on the research that has been carried out, formula 4 is more preferred than other formulas because the results of the physical evaluation test of formula 4 meet all requirements. For the drying time test on formula 1 before and after the stability test, and formula 2 before the stability test the results did not meet the requirements, while for the dispersion test on formula 3 after the stability test, the results did not meet the requirements.
IDENTIFIKASI RHODAMIN B PADA PRODUK KOSMETIK YANG BEREDAR SECARA ONLINE Harpolia Cartika; Khairun Nida; Yetri Elisya
Jurnal Farmasi IKIFA Vol. 2 No. 2 (2023): JURNAL FARMASI IKIFA VOL.2 NO.2 OKTOBER TAHUN 2023
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The results of the routine supervision of the POM Agency, Red Dye K3 and Rhodamin B are often misused in cosmetic products. Rhodamine B is a textile dye that is quite harmful to the health of the human body, because it can cause irritation to the respiratory tract, damage to the liver, and cancer. This research aims to identify the presence of Rhodamin B in eyeshadow, lipstick, and blush circulating online, which using 5 samples for each products. The research method is an experimental method using Thin Layer Chromatography (TLC) to obtain hRf values ​​and calculate rhodamine B levels using UV-Vis Spectrophotometry 254 nm and 366 nm. The results showed that from the fifteen samples studied, 7 samples had an Rf value between 0.61-0.67 with a comparison standard Rf value of Rhodamine B of 0.62. The seven samples consisted of 1 sample of positive blush containing rhodamine B with value of 1.68%, 3 samples of positive eye shadow with values of 2.35%, 3.29%, and 3.26%, and 3 samples of positive lipstick with values of 1.17%, 1.22%, and 0.47%. This shows that 7 out of 15 cosmetic samples contain the harmful substance rhodamine B.
Hubungan Faktor Demografi dengan Pengetahuan Cara Penggunaan Obat Bebas dan Bebas Terbatas di Kelurahan Penggilingan Charles; Meiana Dwi Andini; Guruh Subagya
Jurnal Farmasi IKIFA Vol. 2 No. 2 (2023): JURNAL FARMASI IKIFA VOL.2 NO.2 OKTOBER TAHUN 2023
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Various health problems, especially those related to drugs, are still found in society. Starting from wrong use, drug abuse, the occurrence of drug side effects from the mildest to fatal. In order to avoid these negative impacts, it is necessary to provide adequate information to the public regarding how to obtain medicines correctly, use medicines correctly, store medicines correctly, and dispose of medicines correctly. Correct use of drugs will increase the success of therapy, incorrect use will increase therapy failure. People's efforts to treat themselves are known as self-medication. Self-medication can be a source of medication errors due to limited public knowledge of drugs and their use. The aim of this research is to determine the relationship between demographic factors and knowledge of how to use over-the-counter drugs and limited over-the-counter drugs in the community in Palasan Village, East Jakarta. This research is a non-experimental research with a total of 196 respondents. This research method is quantitative research. Based on the research results, it is known that overall 110 respondents (56%) had sufficient knowledge regarding the use of free and over-the-counter medicines, 64 respondents (33%) had good knowledge and 22 respondents (11%) had poor knowledge. Statistical tests show that there is no relationship between demographics and limited knowledge of how to use over-the-counter and over-the-counter drugs in the Pisiran sub-district, East Jakarta
Pembuatan Sediaan Lipstik Padat dari Pewarna Alam Antosianin Indri Astuti Handayani; Ika Agustina; Rakhmadhan Niah
Jurnal Farmasi IKIFA Vol. 2 No. 2 (2023): JURNAL FARMASI IKIFA VOL.2 NO.2 OKTOBER TAHUN 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Abstract

Latar belakang: Lipstik salah satu kosmetik dekoratif yang dapat meningkatkan penampilan seseorang dengan memperindah bibir dengan warna yang menarik, melindungi bibir tidak kering, dan dapat menampilkan sisi baik serta menyamarkan bentuk pada bibir. Dengan perkembangan gaya hidup penggunaan pewarna alami mulai menggantikan pewarna sintetis, salah satu pigmen warna yang terdapat pada bahan alami yang dapat digunakan adalah antosianin. Antosianin merupakan senyawa flavonoid yang larut dalam air, dapat digunakan sebagai pewarna alami pada produk makanan dan berbagai aplikasi lainnya. Tujuan :Penelitian ini bertujuan untuk mengetahui hasil evaluasi fisika dan kimia sediaan lipstik padat dari ekstrak beras hitam (Oryza sativa L. indica), beras ketan hitam (Oryza sativa var. glutinosa), beras merah (Oryza Nivara). Metode: Metode ekstraksi yang digunakan adalah maserasi selama 180 menit pada suhu 300C dengan pelarut etanol 96% menghasilkan ekstrak kental. Pembuatan sediaan lipstik padat dilakukan dengan menggunakan dua formula yaitu F0 (basis) dan F1 (ekstrak 25%). Hasil: Penelitian ini menunjukkan warna lipstik yang dihasilkan bervariasi, padat dan homogen, setelah dilakukan uji nyata semua sediaan menunjukkan olesan yang nyata. pH sediaan lipstik berada pada pH 3-4. Kesimpulan pH lipstik belum masuk ke persyaratan yang baik untuk sediaan lipstik.

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