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Fakultas Kedokteran Universitas Halu Oleo, Kampus Hijau Bumi Tridharma Andonuhu, Kendari 93232
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MEDULA Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo
Published by Universitas Halu Oleo
ISSN : 23391006     EISSN : 24430218     DOI : https://doi.org/10.46496
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
MEDULA invites contributions to original and fundamental research in the field of health, which must be submitted for peer reviewed articles. The journals focus and scope are contemporary medicine through biomedical research, genetics, and medical technology, Patient care practices, Disease prevention, Disease epidemiology, Family medicine, Health care center management, New drug development through research on the effectiveness of medicinal plants in treating disease, Development of traditional medicines frequently used by local communities, Utilization of marine biota for medicinal purposes, Social aspects related to the implementation of medical education and other relevant fields
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 50 Documents
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Effect of Ethanol Extract of Miana Leaves (Coleus atropurpureus L. Benth.) on the Growth of Pseudomonas aeruginosa and Staphylococcus epidermidis Sufiah Asri Mulyawati; Angelia Harpahda; Mario Polo Widjaya
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 12 No. 2 (2025): Juli
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

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ABSTRACT Background: Nosocomial infections continue to present a significant challenge in healthcare systems due to their high prevalence and the increasing emergence of antibiotic resistance. The bioactive constituents of miana leaves (Coleus atropurpureus L. Benth.) exhibit potential antibacterial properties, supporting the need to evaluate the effectiveness of their ethanol extract in inhibiting the growth of pathogenic microorganisms. Purpose(s): to evaluate the ability of the ethanol extract of miana leaves (Coleus atropurpureus L. Benth.) to inhibit the growth of Pseudomonas aeruginosa. Methods: A post-test only control group design was employed using miana leaf extract (Coleus atropurpureus L. Benth.) as the treatment variable, cefadroxil as the positive control, and distilled water as the negative control against Pseudomonas aeruginosa, each tested in triplicate, and the antibacterial activity was evaluated using the disc diffusion method at concentrations of 1500 ppm, 2000 ppm, 2500 ppm, and 3000 ppm. Results: The ethanol extract of miana leaves (Coleus atropurpureus L. Benth.) demonstrated strong inhibitory activity against Pseudomonas aeruginosa at concentrations of 1500–3000 ppm, and the One-Way ANOVA results showed a significant difference (p < 0.05), indicating that the extract exhibits a measurable antibacterial effect against Pseudomonas aeruginosa in vitro. Conclusion: The ethanol extract of miana leaves (Coleus atropurpureus L. Benth.) effectively inhibits the growth of Pseudomonas aeruginosa, supported by strong antibacterial activity. Keywords: antibacterial; ethanol extract; Miana leaves (Coleus atropurpureus L. Benth); Pseudomonas aeruginosa
The Effect of Counseling on Mothers Knowledge And Attitudes About Preventing DBD In Children In The Working Area of Poasia Health Center Ryaasti Zalzabila Ramadan; Wa Ode Sitti Asfiah Udu; Arimaswati
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 12 No. 2 (2025): Juli
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ABSTRACT Background. Dengue Hemorrhagic Fever (DHF) is an infectious disease caused by a virus dengue. Poasia Health Center is one of the health centers with the most dengue fever cases. The most patiens occur at ages 4-16 years. DHF cases that occur in children can be caused a lack of knowledge and preventive attitudes carried out within the family. The aim of this research is to determine the effect of counseling on mothers' knowledge and attitudes regarding preventing dengue fever in children in the Poasia Health Center working area. Method. This research is Quasi-Eksperiment with design Without Control Groups Pretest-Posttest Design which was carried out in the Poasia Community Health Center working area. The independent variable being dengue prevention counseling while the dependent variable is the mother's knowledge and attitude. The number of samples in this study is 143 people. Data on maternal knowledge and attitudes were collect using a questionnaire and then analyze using the Wilcoxon test. Results. The dominant age was 20-30 years old with a total of 91 people with a percentage of 63.6% and the dominant last education was high school/equivalent with a total of 53 people with a percentage of 37.1%. A total of 143 respondents experienced an increase in knowledge after the counseling intervention and an increase in attitudes for 140 respondents. The results of testing knowledge and attitude data using the Wilcoxon test showed a value of p= 0.000 (p<0.05). Conclusion. There is an influence of counseling on mothers' knowledge and attitudes regarding preventing dengue fever in children in the Poasia Health Center working area. Keywords: Mother, Dengue Hemorrhagic Fever, Counseling, Knowledge, Attitude
Analysis Of Family Factors, Duration Of Near Work Activities, And Outdoor Activities In Relation To The Degree Of Myopia Among Students At SMPN 1 RAHA In 2025 Saras Dwianugra; Ika Kartika; Nina Indriyani Nasruddin
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 12 No. 2 (2025): Juli
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

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ABSTRACT Backround. Myopia, or nearsightedness, is a refractive error in which parallel rays of light entering the eye are focused in front of the retina instead of directly on it. This condition is often caused by prolonged near work activities over time. This study aims to identify the factors associated with the degree of myopia among students at SMPN 1 Raha, using samples of students previously diagnosed by a physician or other profesional healthcare. Method. This study employed a quantitative analytic observational method with a cross-sectional approach. Primary data were collected using a questionnaire. A total of 84 respondents were selected using purposive sampling based on inclusion criteria. Data were analyzed using SPSS software with the Chi-Square statistical test. Results. Statistical analysis showed that family history (p = 0.026), prolonged duration of near work activities (>10 hours/day) (p = 0.027), and longer duration of outdoor activities (p = 0.006) were significantly associated with the degree of myopia among students at SMPN 1 Raha. Conclusion. Family history, duration of near work activities, and duration of outdoor activities are factors significantly associated with the degree of myopia in students at SMPN 1 Raha. Keywords. Near Work Activities, Outdoor Activities, Myopia Degree, Family Factors, Junior High School Students.
Relationship between Anxiety and Epigastric Pain and Postprandial Distress Syndrome in Medical Students of Halu Oleo University Kendari Rizqi Rayyan Shaffana; Pranita Aritrina S; Edy Husnul Mujahid
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 12 No. 2 (2025): Juli
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Background: Anxiety is a psychological condition in the form of excessive anxiety that is often experienced by medical students due to the influence of high academic loads being one of the factors causing anxiety disorders involving digestive disorders, triggering the occurrence of Epigastric Pain Syndrome and Postprandial Distress Syndrome. Purpose(s): This study aims to determine whether there is a relationship between anxiety and Epigastric Pain Syndrome and Postprandial Distress Syndrome in students of the Faculty of Medicine, Halu Oleo University. Methods: This study was an observational analytic study using a cross-sectional approach method of Halu Oleo University Faculty of Medicine students from the Class of 2021, 2022, and 2023, obtained a total sample of 190 samples taken using proportional stratified random sampling technique. Data were collected using the Hamilton Anxiety Rating Scale (HARS) and R4-FDDQ (Rome IV Functional Dyspepsia Diagnostic Questionnaire) questionnaires using the Chi Square test. Results: In this study showed a significant relationship between anxiety levels and the incidence of Epigastric Pain Syndrome (EPS) p-value = <0.001 and there was a significant relationship anxiety levels and the incidence of Postprandial Distress Syndrome (PDS) p-value = <0.001 in students of the Faculty of Medicine, Halu Oleo University. Conclusion: There is a significant relationship between anxiety and Epigastric Pain Syndrome and there is a significant relationship between anxiety and Postprandial Distress Syndrome in students of the Faculty of Medicine, Halu Oleo University Kendari
Relationship Between Risk Factors Affecting the Occurrence of Diabetic Ulcer Classification in Patients with Type 2 Diabetes Mellitus in Kendari City Hospital Andi Nur Meilia Jufriyani; Tomy Nurtamin; Adry Leonardy Tendean
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 12 No. 2 (2025): Juli
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Background. Diabetes mellitus is a metabolic disease caused by the body being unable to produce insulin hormone or peripheral insulin resistance. This chronic hyperglycemia condition can cause complications of diabetes mellitus, one of which is diabetic ulcers. Diabetic ulcer is a chronic complication of diabetes mellitus caused by several factors that can affect it. Some of these factors are age, comorbidities, length of suffering and drug compliance which play a role in causing diabetic ulcers. This study aims to determine the relationship between several factors that cause the classification of diabetic ulcers in patients with type 2 diabetes mellitus at Kendari City Hospital. Methods. This study was conducted with observational analytic method with cross sectional approach conducted at Kendari City Hospital with 62 respondents. Data were collected and analyzed using Fischer's exact test with a significant value of p≤ 0.05. Results. This study shows that there is a significant relationship between the age variable and the classification of diabetic ulcers with a p-value of 0.04, a significant relationship between comorbidities and the classification of diabetic ulcers with a p-value of 0.00, there is no significant relationship between the duration of DM and the classification of diabetic ulcers with a p-value of 0.15, and there is a significant relationship in drug compliance and the classification of diabetic ulcers with a p-value of 0.00. Conclusion. There is a significant relationship between three risk factors such as age, comorbidities, and medication compliance with the occurrence of diabetic ulcer classification. And there is no significant relationship between the duration of DM and the occurrence of diabetic ulcer classification in type 2 diabetes mellitus patients at Kendari City Hospital. This underlines the importance of avoiding factors that can cause complications of diabetes mellitus in the form of diabetic ulcers.
Identification Of Bacteria Causing Nosocomial Infections In Patients In The Care Ward At Kendari City General Hospital In 2023 Sufiah Asri Mulyawati; Laode Kardin; Nina Indriyani Nasruddin; Edy Husnul Mujahid; Tsalsa Anto Ifdanunnisa
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 13 No. 1 (2025): Desember
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ABSTRACT Background: Bacteria are microorganisms that have a single cell, prokaryotes. Normal skin is usually occupied by bacteria around 102-106 CFU/ml. Purpose(s): This study aims to determine the characteristics of the bacteria from hand swabs in ward patients at the Kendari City Regional General Hospital in 2023. Methods: This research is an observational descriptive study. The research sample was taken from the patients in patient room. The samples obtained were then cultured at the Microbiology Laboratory, Faculty of Medicine, Halu Oleo University. Analyzed descriptively and displayed in tabular form. Results: The results showed that there was growth of bacterial colonies. The bacteria found in the samples from the patient's hand swabs were Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus sp., Bacillus sp., Enterobacter sp. Conclusion: There was growth of bacterial colonies obtained from the results of hand swabs of ward care patients at the Kendari City Regional General Hospital.
Difference in Intraocular Pressure Before and After Cataract Surgery with Glaucoma Complications at Kendari Eye Clinic Amiruddin Eso; Deni Sastra Mandarin; Melvin Manuel Philips
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 13 No. 1 (2025): Desember
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Background: Cataracts and glaucoma are the leading causes of irreversible blindness worldwide and frequently coexist in elderly populations. Cataract-induced structural changes in the anterior segment may impair aqueous humor outflow, resulting in elevated intraocular pressure (IOP) and accelerated optic nerve damage in patients with glaucoma. Purpose(s): This study aimed to analyze differences in IOP before and after cataract surgery among patients with glaucoma complications at Kendari Eye Clinic. Methods: An observational analytic study with a pre–post cross-sectional design was conducted using medical record data from January to June 2024. A total of 100 patients with senile cataracts complicated by glaucoma who underwent phacoemulsification were included using purposive sampling. IOP measurements were obtained using a non-contact tonometer before surgery and at 3 days, 5 days, 12 days, and 1 month postoperatively. Data were analyzed using the Friedman test. Results: The results demonstrated a statistically significant difference in IOP before and after surgery (p < 0.001). Mean IOP increased transiently at 3 days postoperatively but decreased significantly at subsequent follow-up intervals. Conclusion: Phacoemulsification cataract surgery significantly reduces IOP in patients with glaucoma complications, emphasizing its role not only in visual rehabilitation but also in IOP control and glaucoma management.
The Relationship Between Sleep Quality and Bedtime With the Incidence of Acne Vulgaris Among 11th Grade Students at SMAN 4 Kendari Indah Sayyidatul Annisa; Siti Andayani; I Putu Sudayasa; Edy Husnul Mujahid; Yenti Purnamasari; Nelly Herfina Dahlan
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 13 No. 1 (2025): Desember
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Background: Acne vulgaris is an inflammatory disease of the pilosebaceous unit that commonly affects adolescents and young adults. The causes of acne vulgaris are multifactorial, involving various internal and external factors, among which sleep quality and bedtime are significant contributors. Poor sleep quality and late bedtime may lead to a decrease in melatonin levels. Reduced melatonin levels can result in increased androgen hormone synthesis, which in turn stimulates sebaceous gland activity and contributes to the development of acne vulgaris. Purpose(s): This study aims to determine the relationship between sleep quality and bedtime with the incidence of acne vulgaris among 11th-grade students at SMAN 4 Kendari. Methods: This study is an observational analytic research with a cross-sectional approach. The sampling method used was simple random sampling, involving a total of 90 students. Data on sleep quality and bedtime were collected through questionnaires, while the incidence of acne vulgaris was assessed through facial screening. Data were analyzed using the chi-square statistical test. Results: Based on the results of the chi-square test using statistical software, a p-value of 0.01 was obtained. A p-value <0.05 indicates that the null hypothesis (H0) is rejected and the alternative hypothesis (Ha) is accepted. Conclusion: There is a relationship between sleep quality and bedtime with the incidence of acne vulgaris among 11th-grade students at SMAN 4 Kendari (p-value = 0.01).
Completeness of Informed Consent Documentation in the Medical Records of Surgical Patients at Hospital X Kendari Fatma Kurniasih; Juminten Saimin; Waode Sitti Asfiah Udu
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 13 No. 1 (2025): Desember
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Background: An informed consent form is essential to ensure that a patient comprehends all the provided information before making a decision and giving consent. It is crucial for patients to understand the proposed medical actions thoroughly. Completing informed consent forms is vital as they serve as legal documentation to protect patients from any medical procedures and ensure healthcare protection in case of unforeseen harmful events. Purpose(s): This research aims to assess the completeness of informed consent forms in the medical records of surgical patients at Hospital X Kendari in 2024. Methods: This research is an observational descriptive study with a cross-sectional approach. It was conducted at Hospital X Kendari, utilizing 92 samples of informed consent forms for surgical procedures in 2023. Data collection was carried out using checklist sheets. Results: The results showed that the completion of informed consent forms was 90% complete for the identity identification component, 85% for the important report component, 99% for the declaration of consent to action component, and 97% for the authentication component. Conclusion: The analysis of the overall completeness of informed consent foms for surgical patients in 2023 showed a completion rate of 93%.
Holistic Diagnosis and Comprehensive Management of a 30-Year-Old Pregnant Woman (Mrs. N) with High-Risk Pregnancy due to Chronic Energy Deficiency and Anemia at Bangetayu Community Health Center, Semarang Fatuh Rohman; Ratnawati; Aris Maulana
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 13 No. 1 (2025): Desember
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ABSTRACT Background: High-risk pregnancy conditions, such as chronic energy deficiency (CED) and anemia, are significant public health concerns impacting both maternal and fetal outcomes. Purpose(s): This research aims to conduct a more in-depth study on the case of chronic energy deficiency (CED) and anemia in patient Ms. N at Sembungharjo Village, Bangetayu Health Center, Semarang. Methods: This case study examines a 30-year-old woman (Mrs. N) with a 28-week pregnancy complicated by CED (upper arm circumference 22.5 cm) and anemia (hemoglobin 10.1 g/dL) at Bangetayu Community Health Center, Semarang. A holistic diagnostic approach involving medical history, nutritional status, and family and environmental factors was carried out. Interventions included iron and folic acid supplementation, fortified food provision, and intensive health education—targeting both the patient and her family. Results: Results showed the patient’s knowledge and dietary practices were key contributors to persistent nutritional deficiencies. Functional family support and multidisciplinary collaboration between the health centre team, community cadres, and family members were emphasized for effective management. The study underlines the necessity of early nutritional and preventive interventions during pregnancy to mitigate risks of stunting and adverse neonatal outcomes. Conslusion: Comprehensive, community-oriented, and family-centered care is vital for improving health in high-risk pregnancies at the primary care level.

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