cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
MEDULA
Contact Email
medulafk@uho.ac.id
Phone
+628114058258
Journal Mail Official
medulafk@uho.ac.id
Editorial Address
Fakultas Kedokteran Universitas Halu Oleo, Kampus Hijau Bumi Tridharma Andonuhu, Kendari 93232
Location
Kota kendari,
Sulawesi tenggara
INDONESIA
MEDULA Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo
Published by Universitas Halu Oleo
ISSN : 23391006     EISSN : 24430218     DOI : https://doi.org/10.46496
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
MEDULA invites contributions to original and fundamental research in the field of health, which must be submitted for peer reviewed articles. The journals focus and scope are contemporary medicine through biomedical research, genetics, and medical technology, Patient care practices, Disease prevention, Disease epidemiology, Family medicine, Health care center management, New drug development through research on the effectiveness of medicinal plants in treating disease, Development of traditional medicines frequently used by local communities, Utilization of marine biota for medicinal purposes, Social aspects related to the implementation of medical education and other relevant fields
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 50 Documents
 1   2   3   4   5 
The Differences in VAS Values Before and After Physiotherapy in Low Back Pain Patients at the Orthopedic Polyclinic, Santa Anna Hospital, Kendari Wa Ode Nur Dian Al Janna; Asriati; Mario Polo Widjaya
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 10 No. 3 (2023): Suplemen
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Low Back Pain (LBP) is an unpleasant condition accompanied by activity limitations caused by pain when moving. Physiotherapy conducted on LBP patients is intended to reduce pain and restore functional abilities. This study aims to determine the differences in VAS values ​​before and after physiotherapy conducted on LBP patients at the Orthopedic Poly of Santa Anna Kendari Hospital. Methods: This observational analytical study used a cross-sectional approach. The study used secondary data in the form of medical records from 30 LBP patients who were undergoing physiotherapy. The observed dependent variable was the VAS value before physiotherapy and the independent variable observed was the VAS value after physiotherapy. The data analysis used the Wilcoxon statistical test. If the value was p≤0.05. Results: The Wilcoxon analysis test showed that there was a significant difference in VAS values ​​(p≤0.05) before and after physiotherapy conducted on LBP patients at the Orthopedic Poly of Santa Anna Kendari Hospital. Conclusion: There is a difference between the VAS values ​​before and after physiotherapy conducted on LBP patients at the Orthopedic Poly of Santa Anna Kendari Hospital.
Difference In VAS Value Before and After Physiotherapy In Osteoarthritis Patients At The Noble Heart General Hospital Kendari Pingki; Muhammad Rustam; La Rangki
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 10 No. 3 (2023): Suplemen
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Osteoarthritis (OA) is a joint disease that most often occurs in adulthood to old age throughout the world, according to the world health organisation (WHO) in 2014 stated that the world's population experiencing osteoarthritis is 335 million people worldwide. Risk factors that affect the incidence of Osteoarthritis include age, gender, obesity, genetics, joint injury, exercise and work, and other risk factors. One of the OA treatments is physiotherapy to reduce the pain intensity of Osteoarthritis sufferers. This study aims to determine the difference in VAS values before and after physiotherapy in Osteoarthritis patients at the Mulia Hati General Hospital Kendari. Method: This study used a descriptive analytic method with a cross sectional approach. This research was conducted at the Mulia Hati General Hospital Kendari from November to December 2022. This sampling uses total sampling that meets the inclusion criteria with a total sample of 37 patients. Data analysis using the Wilcoxon test. Result: The results showed a P value of 0.000 (p value <0.05), so Ha was accepted, which means that the results of the research conducted showed a difference in VAS values before and after physiotherapy. Conclusio:. The conclusion of this study is a decrease in VAS value after physiotherapy is performed at the Mulia Hati General Hospital Kendari.
Study of Correlation between Used Cooking Oil and Triglyceride Profile on Hypertension in Coastal Communities in Nambo Village, Kendari Prabowo S. Yuwana; I P. Sudayasa; Tien; Pranita Aritrina
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 10 No. 3 (2023): Suplemen
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: According to the World Health Organization (WHO) in 2008, in Southeast Asia, as many as 36% of adults aged 25 years and over had high blood pressure, and 1.5 million deaths occur each year due to complications of high blood pressure. In Indonesia, hypertension is still a big challenge. This is a health problem with a high prevalence of 25.8% according to Riskesdas data in 2013. Hypertension is a chronic increase in blood pressure 140/90 mmHg. Non-pharmacological therapy needs to be applied to prevent the occurrence of hypertension, namely by modifying lifestyle to control blood pressure. Used cooking oil contains free fatty acids formed from the process of oxidation and hydrolysis, then these free fatty acids reshape saturated fatty acids and trans fatty acids and free radicals, which can cause various disorders such as endothelial dysfunction, which can lead to hypertension. Purpose(s): The purpose of this study was to determine the correlation between the used cooking oil and triglyceride profile with hypertension. Methods: The design of this study was observational analytic with cross-sectional research design. The sample of this study amounted to 96 people with purposive sampling technique. The instrument of this study was Questionnaire to determine the used cooking oil and automatic Spectrophotometer (TRX-7010) to measure triglyceride profiles. Data analysis was performed by chi-square test with significance value p < 0,05. Results: The results of this study showed that there was a correlation between the used cooking oil and hypertension (p = 0.002) and triglyceride profile with hypertension (p = 0.004). Conclusions: Hypertension had a correlation with the used cooking oil and increase in triglycerideprofile.
Correlation Of Age And BMI With The Incident Of Nausea And Vomiting In Patients Post Sectio Caesarian Operation With Spinal Anesthesia In Aliyah Hospital 2 Agussalim Ali; Parawansah; Sulastrianah
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 10 No. 3 (2023): Suplemen
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background. Postoperative nausea and vomiting are one of the complications experienced by patients with anesthesia and surgery. There are many factors that influence this occurrence, including age and BMI, where young age and obese BMI tend to experience postoperative nausea and vomiting. This is based on the fact that older age is easier to control nausea and vomiting than young people and obese BMI has more fat tissue to store anesthetic drugs so that the side effects of drugs can last longer. Method. This study used an observational analytic method with a cross sectional approach carried out at Aliyah Hospital 2. The number of samples in this study were 38 people who were taken using total sampling technique. Data collection was obtained from filling in the observation sheet and then the data was analyzed using the Fisher's Exact Test statistical test. The dependent variable in this study was postoperative nausea and vomiting and the independent variables were age and BMI. Results. The results of this study found that age did not have a significant relationship with the incidence of postoperative nausea and vomiting at Aliyah Hospital 2 (p = 0.298) and BMI had a significant relationship with the incidence of postoperative nausea and vomiting at Aliyah Hospital 2 (p = 0.019). Conclusion. From this study it can be concluded that the incidence of postoperative nausea and vomiting after spinal anesthesia is higher in patients with older age and excessive BMI.
The Impact of the Ethyl Acetate Fraction of Bitter Melon Fruit (Momordica charantia l.) on Insulin Hormone Levels of Diabetic Rats (Rattus norvegicus) Using the Enzyme-Linked Immunosorbent Assay Method Parawansah; Tien; Amiruddin Eso; Muhammad Junaid Azis; Nuralifah
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 10 No. 3 (2023): Suplemen
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: The World Health Organization (WHO) has forecast a rise in the prevalence of diabetes mellitus from 2.8% in 2000 to 4.4% in 2030. Numerous investigations have been undertaken to identify alternate avenues for antidiabetic treatment. Momordica charantia, sometimes referred to as bitter melon, is recognized for its possession of mimic insulin components. The ethanol extracts derived from Momordica charantia have been found to exhibit favorable outcomes in the reduction of blood glucose levels and the stimulation of pancreatic beta cells for the secretion of insulin hormone. Purpose: The purpose of this research is to investigate the impact of bitter melon extract on insulin levels in rats induced with streptozotosin. Method: The present study employed various methodologies to investigate the research question. The present investigation comprised three distinct sets of tests, specifically streptozotosin-induced rats, streptozotosin-induced rats administered with an ethyl acetate fraction of Momordica charantia extract, and non-induced streptozotosin rats. The measurement of insulin levels is conducted using the enzyme-linked immunosorbent assay (ELISA) technique. If the p-value was more than 0.05, an unpaired T-test was employed for data analysis. Result: The research findings indicate that there is no statistically significant distinction in the insulin levels between streptozotosin-induced rats and streptozotosin-induced rats administered with the ethyl acetate fraction of the Momordica charantia extract group (p = 0.081). The insulin levels of streptozotosin-induced rats administered with an ethyl acetate fraction of Momordica charantia extract were found to be statistically similar to those of non-induced streptozotosin rats (p = 0.505). Conclusion: There is no discernible distinction in the insulin levels among streptozotosin-induced rats, streptozotosin-induced rats administered with an ethyl acetate fraction of Momordica charantia extract, and non-induced streptozotosin rats.
Correlation between Knowledge and Attitude with Malaria Prevention Practices in the Working Area of the Kabawo Public Health Center Arimaswati; Ninis I. Octasari; Ashaeryanto; Indria Hafizah; Pranita Aritrina
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 11 No. 1 (2023): Akhir
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Malaria is still one of the public health problems in Southeast Sulawesi Province. Annual Parasite Incidence (API) in the work area of Kabawo Primary Health Center was 48.90‰ in 2016. Limited public knowledge is an essential determinant of the emergence of malaria and influences community participation in malaria prevention programs. Purpose: This research aims to determine the relationship between knowledge and behavior in malaria prevention practices in the work area of Kabawo Primary Health Center. Methods: This research was an observational analytic design using a cross-sectional approach. The dependent variable in this research was malaria prevention practice, and the independent variable was knowledge and behavior. The research location was in the Kabawo Primary Health Center's working area, with 56 respondents using the total sampling method. Data were obtained by filling out the knowledge questionnaires, behaviors and practices, and interviews. Data analysis used a spearman rank statistical test with a p-value <0.05 and contingency coefficient (r-value). Result: The result of this research of 56 respondents found 22 respondents (39.3%) had good knowledge, good behavior, and good prevention practices, as many as 12 respondents (21.4%) had good knowledge, good behavior, and less of prevention practices, as many as 22 respondents (39,3%) have less knowledge, less behavior and less of prevention practices. Based on the results of the Spearman rank statistical test analysis, it was found that the knowledge and behaviors with malaria prevention practices showed the p-value of 0,000 <0,05 with the value r = 0,647. Conclusion: This research concluded that there was a relationship between knowledge and behaviors to prevention practices in the work area of Kabawo Primary Health Center and had a strong correlation between variables with a positive correlation direction, meaning that the better knowledge and behaviors, the better prevention practices.
Advanced Glycation End-Product (AGEs)Level in a Diabetic Rat Model Treated with Warfarin Anticoagulant Musyarrafah; Halia Wanadiatri; I G.A. Adnyana
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 11 No. 1 (2023): Akhir
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Diabetes mellitus is a chronic disease that is the most seriously cause of macrovascular and microvascular complications that threaten life , expensive and reduces life expectancy. The occurence of cell damage and inflammation due to AGEs and RAGE reactions generally exacerbates the risk of macrovascular complications . Pharmacological therapy given to prevent these complications is the warfarin anticoagulant . the duration of warfarin use can increase the hardening of blood vessels or vascular calcification and is compounded by AGEs accumulation and RAGE activation. Objective: To analyze plasma AGE levels as a risk factor for vascular calcification in DM and non-DM rats models treated with warfarin anticoagulants. Method: This study used a Quasi experimental method with a posttest only control group design. The total sample was 28 samples divided into 4 groups, each group consisting of 7 rats grouped into DM + Aquadest group, DM + Warfarin group, non-DM + Aquadest group , and non-DM + Warfarin group. Plasma AGE levels were measured using the ELISA method and the results were analyzed using Anova. Results: AGE Level in the DM + Warfarin group (Mean= 1.183; SD=0.16) was slightly high than AGE level in normal rat group with Warfarin induction (Mean=1,012; SD=0,02). In the normal rat group treated with Aquadest was slightly low than AGE level in the DM rat group with warfarin induction (Mean=1.147; SD=0.13). Interestingly, There was no difference in plasma AGE levels between groups (p=0,155). Conclusion: AGE levels at the onset of DM are not yet able to progressively activate vascular damage through the AGE/RAGE signaling pathway.
The Impact of Carbonated Sodium Bicarbonate Drinks on Physical Fitness in Adolescents Rahma Badaruddin; Nur A. Salikunna; Moh. Z. Ramadhan; Andi A.M. Tanra; Ikwanul Muslimin
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 11 No. 1 (2023): Akhir
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Physical fitness is a crucial factor for individuals to support their daily physical activities. Soda beverages have gained popularity among adolescents and are believed to affect physical fitness. Objective: This study investigated the influence of soda consumption on the physical fitness of adolescents. Methods: The study included 30 male participants with 18-25 years old who voluntarily participated and willingly provided informed consent. Physical fitness was measured before and after carbonated sodium bicarbonate drinks consumption using the Harvard Step Test. Participants orally consumed NaHCO3 at a dose of 0.3 gr/kg of body weight in carbonated water at a dose of 0.4 ml/kg of body weight. The employed statistical test was the T-test. Results: The average physical fitness score of the participants before soda consumption was 34.37 ± 13.465, while the average score after soda consumption was 51.57 ± 20.100. The T-test yielded a score of 0.001. Conclusion: Based on the statistical analysis, it can be concluded that carbonated sodium bicarbonate drinks can enhance physical fitness in adolescents.
Diagnosing Performance of Matrix Metalloproteinase-9 (MMP-9) and Alberta Stroke Program Early CT Score (ASPECTS) as The Clinical Degree Predictor of Ischemic Stroke: Which One is Better ? Ashaeryanto; Muhammad Akbar; Muhammad I. Basri; Gita V. Soraya; Ashari Bahar; Cahyono Kaelan
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 11 No. 1 (2023): Akhir
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Matrix metalloproteinase-9 (MMP-9) and Alberta Stroke Program Early CT Score (ASPECTS) are predictors of the ischemic stroke clinical degree. A marker with good performance is needed to estimate the clinical degree following an ischemic stroke attack. Puropose(s): Analyze the comparison of MMP-9 levels with ASPECTS as a predictor of the clinical degree of ischemic stroke. Methods: Analytical study with a prospective cohort design. This study sample consisted of middle cerebral artery ischemic stroke patients at RSUP Dr. Wahidin Sudirohusodo and Network Hospital with a total of 32 patients. The MMP-9 level was measured by using the ELISA method, while ASPECT was assessed based on the head CT scan. Clinical degree assessment according to the National Institute of Health Stroke Scale (NIHSS). Spearman and Receiver Operating Characteristic (ROC) tests were performed to determine sensitivity and specificity. Results: ASPECTS sensitivity and specificity values on NIHSS admission: 85.71% and 90.91%, NIHSS day 14: 70.37% and 100%. Sensitivity and specificity of MMP-9 on NIHSS admission: 72.73% and 76.19%, NIHSS day 14: 100% and 70.73%. Conclusion: ASPECTS has a stronger specificity level than MMP-9 as a predictor of the pure clinical degree of ischemic stroke, and MMP-9 has a stronger sensitivity value than ASPECTS as a predictor pure clinical degree day 14.
Accuracy of Multiparametric Magnetic Resonance Imaging (MRI) in Determining Prostate Malignancy Based on Histopathological Results Hendrick Revian; Mirna Muis; Rafikah Rauf; Muhammad A.A. Palinrungi; Andi A. Zainuddin
MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo Vol. 11 No. 1 (2023): Akhir
Publisher : MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Prostate cancer is the most common malignancy in men in many regions of the world and is the second cause of cancer death in men as well as the third most common urological cancer in Indonesian men. One of the radiology examinations used to detect prostate cancer is multiparametric MRI which is a series of prostate magnetic resonance combining anatomical and functional imaging to detect and characterize prostate lesions. Purposes: This study aims to assess the accuracy of multiparametric prostate MRI in detecting prostate cancer based on the results of histopathological examination. Methods: This research used sensitivity value, specificity value, positive prediction value, and negative prediction value as well as Chi-Square test (P value < 0.05) to assess accuracy in SPSS program version 25. Results: This research was conducted at the central radiology installation of Dr. Wahidin Sudirohusodo Hospital and Hasanuddin University Hospital Makassar from February 2022 to July 2022, with 40 samples were obtained. Most samples were at the age of 60-70 years with 18 samples (45%), the most common lesion site was in the transitional zone with 19 samples (47.5%), multiparametric MRI results were predominant in the PIRADS 2 group with total sample of 18 (45%), PIRADS grading was obtained from benign categories (PIRADS 1 and 2) as much as 18 samples (45%) and from malignancy categories (PIRADS 3-5) with 22 samples (55%). Histopathological examination obtained benign results (BPH and prostatitis) in 21 samples (52.50%) and malignant in 19 samples (47.5%). Conclusion: We found correlation between multiparametric prostate MRI dan histopathological results by using bivariate correlation test with p values < 0.001. Multiparametric prostate MRI sensitivity value 100%, specificity 85.7%, positive prediction value 83.3%, Negative Prediction Value 100%, and accuracy 92.5%.

Page 3 of 5 | Total Record : 50

 1   2   3   4   5 

Filter by Year

2022 2025


Reset
Filter By Issues
All Issue Vol. 13 No. 1 (2025): Desember Vol. 12 No. 2 (2025): Juli Vol. 12 No. 1 (2024): Desember Vol. 11 No. 2 (2024) Vol. 11 No. 1 (2023): Akhir Vol. 10 No. 3 (2023): Suplemen Vol. 10 No. 2 (2023): April Vol. 10 No. 1 (2022): Oktober